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Author : P. A. Bastenie
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)
Download or read book Immunity and Autoimmunity in Diabetes Mellitus written by P. A. Bastenie and published by . This book was released on 1974 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Thomas Dyrberg
Publisher : Springer Science & Business Media
ISBN 13 : 364275239X
Total Pages : 148 pages
Book Rating : 4.6/5 (427 download)
Download or read book The Role of Viruses and the Immune System in Diabetes Mellitus written by Thomas Dyrberg and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in diabetes has accelerated in two areas, both of which are being reviewed in CTMI. The first is the use of a variety of animal models; the second is basic research in human investigation, islet cell antigens, and mapping of genes as sociated with susceptibility to disease. Dr. Thomas Dyrberg accepted editorial responsibility for this volume, which covers the first area. A second book, to be published later in the year, is edited by Drs. Brekkeskov and Hansen (CTMI 164, see page VI for contents). Although the contributors to both volumes represent the international scientific community, the editors are from the Hagedorn Research Laboratory in Denmark. Work at this institute and the Steno Memorial Hospital has been dedicated to research in diabetes for decades, and the insti tutions were appointed WHO Collaborating Centres for Re search and Training on the Pathogenesis of Diabetes Mellitus in 1983. It is worth noting that while addressing the hypothesis of the role of class II major histocompatibility glycoproteins in autoimmune diabetes (insulin-dependent diabetes, IDDM) a number of investigators established animal models in which class II molecules were expressed under the control of the rat insulin promoter. While generating interesting information on 100M, the finding of immunologic tolerance in such transgenic mice has attracted the attention of several basic immunologic laboratories for quite different reasons. Thus, we are reminded again of the Pasteur dictum that "chance favors the prepared mind. " Michael B. A. Oldstone, M. D.
Author : Gerald Michael Addison
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (164 download)
Download or read book Immunity and autoimmunity in diabetes mellitus written by Gerald Michael Addison and published by . This book was released on 1974 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Domenico Andreani
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.3/5 (91 download)
Download or read book Immunotherapy of Type 1 Diabetes written by Domenico Andreani and published by John Wiley & Sons. This book was released on 1989 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent national, European and international diabetes meetings have seen controversial discussions on the potential benefit and also on ethical aspects of immune intervention in patients with Type 1 diabetes or in persons with a high risk of developing the disease.
Author : Fredda Ginsberg-Fellner
Publisher : Springer Science & Business Media
ISBN 13 : 146123218X
Total Pages : 448 pages
Book Rating : 4.4/5 (612 download)
Download or read book Autoimmunity and the Pathogenesis of Diabetes written by Fredda Ginsberg-Fellner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been a challenge for us to edit this volume of Endocrinology and Metabo lism: Progress in Research and Clinical Practice. The topic of the pathogenesis of insulin-dependent, type I diabetes mellitus is particularly appropriate for this series, since advances in this area have been made, to a large extent, by applying state-of-the-art laboratory techniques to clinical samples. Over the last several years, a number of lines of evidence have been gathered, suggesting that classic type I diabetes mellitus results from the autoimmune des truction of pancreatic beta-cells in genetically susceptible individuals. This hypothesis is particularly appealing because it offers a rational approach to the prevention of diabetes by immunosuppression. We have tried to present a balanced, authoritative summary of the information currently available to support the autoimmune hypothesis for the pathogenesis of human type I diabetes, to place this information in historical perspective, to include relevant information from animal models of type I diabetes in which more invasive experimentation is ethical, and, finally, to update the reader on the current status of attempts to intervene in the progression of diabetes with immunosuppressive drugs. New York, New York Fredda Ginsberg-Fellner Robert C. McEvoy Contents Preface.. . . .. .. .. . . . . . . . . . . . . ... . . . . . . . . . . . .. . . . . . . .. . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Xl . . . . . . . . . . . . . 1. The Autoimmune Hypothesis of Insulin-Dependent Diabetes: 1965 to the Present . . . . . . . . . . . . ..................... . . . . . .
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : R.C. Kennedy
Publisher : Elsevier
ISBN 13 : 0080534430
Total Pages : 557 pages
Book Rating : 4.0/5 (85 download)
Download or read book Idiotypes in Medicine: Autoimmunity, Infection and Cancer written by R.C. Kennedy and published by Elsevier. This book was released on 1997-11-19 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
Author : Matthias G. Von Herrath
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805572409
Total Pages : 371 pages
Book Rating : 4.8/5 (55 download)
Download or read book Molecular Pathology of Type 1 Diabetes Mellitus written by Matthias G. Von Herrath and published by Karger Medical and Scientific Publishers. This book was released on 2001-01-01 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Type 1 diabetes as well as multiple sclerosis are thought to be T cell mediated autoimmune diseases that involve a detrimental action of inflammatory cytokines and autoaggressive T lymphocytes. They still pose many unsolved puzzles, and the precise etiology as well as prevention have remained elusive. It is clear that genetic factors can predispose for developing diabetes, however, based on significant disease discordance found in monozygotic twins, additional environmental factors have to be postulated. Viruses are good candidates because they induce strong cellular and humoral immune responses, but no single etiologic agent has been identified. Several animal models are presented which have been used to study the activation of naive autoreactive lymphocytes. It is shown that regulation of the autoaggressive process occurs prior to clinical diabetes and is mediated by a complete network of cytokines, as well as regulatory circuits/cells. The spreading of autoimmunity to self-antigens not involved in the initial phase of islet destruction is not necessarily detrimental and can carry benefits. Therapeutically, counter-regulation of aggressive responses has been demonstrated via various means in animal models preventing diabetes or rejection of transplanted islets.
Author : Immunology of Diabetes Society. Congress
Publisher :
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.X/5 (4 download)
Download or read book Immunology of Diabetes written by Immunology of Diabetes Society. Congress and published by . This book was released on 2002 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers included here examine all aspects of diabetes immunology, including studies on the genetics, pathogenesis, prediction, prevention and treatment of the disease. A particular emphasis is given to the human model of the disease as well as to advances in the broader fields of immunology and autoimmunity.
Download or read book IMMUNITY AND AUTOIMMUNITY IN DIABETES MELLITUS- PROCEEDINGS OF THE FRANCQUI FOUNDATION COLLOQUIUM. written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : George S. Eisenbarth
Publisher : CRC Press
ISBN 13 : 1351090348
Total Pages : 359 pages
Book Rating : 4.3/5 (51 download)
Download or read book Immunotherapy of Diabetes and Selected Autoimmune Diseases written by George S. Eisenbarth and published by CRC Press. This book was released on 2019-08-08 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important text will be the first devoted to a detailed analysis of immunotherapy as it applies to Type I diabetes and the pathogenesis and therapy of other specific autoimmune diseases (including uveitis, multiple sclerosis, myasthenia gravis, Cogan's syndrome, Graves' ophthalmopathy, and gonadal disorders).
Author : Mark A. Sperling
Publisher :
ISBN 13 : 9781416027539
Total Pages : 0 pages
Book Rating : 4.0/5 (275 download)
Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : George S. Eisenbarth
Publisher : Springer Science & Business Media
ISBN 13 : 1603274782
Total Pages : 573 pages
Book Rating : 4.6/5 (32 download)
Download or read book Immunoendocrinology: Scientific and Clinical Aspects written by George S. Eisenbarth and published by Springer Science & Business Media. This book was released on 2010-12-13 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunoendocrinology is a rapidly developing field of research that seeks to understand the intersection of the immune and endocrine systems. Immunoendocrinology: Scientific and Clinical Aspects explores in detail the current knowledge of immunoendocrinology, namely endocrine disorders produced by disorders of immune function. Chapters cover both basic pathophysiology informed by studies of animal models as well as current understanding of multiple related clinical diseases—their pathophysiology, diagnosis, and therapy. Immunoendocrinology: Scientific and Clinical Aspects captures the central role of immunoendocrinologic processes in the pathogenesis of not only type 1 diabetes but in a range of other autoimmune and endocrine disorders.
Author : Nadir R. Farid
Publisher : CRC Press
ISBN 13 : 9780849368974
Total Pages : 240 pages
Book Rating : 4.3/5 (689 download)
Download or read book The Immunogenetics of Autoimmune Diseases written by Nadir R. Farid and published by CRC Press. This book was released on 1990-11-21 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex
Author : Arnaud Zaldumbide
Publisher : Frontiers Media SA
ISBN 13 : 2889746712
Total Pages : 149 pages
Book Rating : 4.8/5 (897 download)
Download or read book Autoimmune Diabetes: Molecular Mechanisms and Neoantigens written by Arnaud Zaldumbide and published by Frontiers Media SA. This book was released on 2022-03-14 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Giuseppe Orlando
Publisher : Academic Press
ISBN 13 : 0128148322
Total Pages : 560 pages
Book Rating : 4.1/5 (281 download)
Download or read book Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas written by Giuseppe Orlando and published by Academic Press. This book was released on 2019-11-10 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 2, sets a new standard in transplant and regenerative medicine. The book details the state-of-the-art in modern islet auto-transplantation, also discussing current progress in regenerative medicine research in diabetes medicine. Regenerative medicine is changing the premise of solid organ transplantation, hence this volume catalogs technologies being developed and methods being implemented. Bioengineering and regenerating beta cells, clinical pancreas and islet transplantation, tissue engineering, biomaterial sciences, stem cell biology and developmental biology are all addressed and applied directly to diabetes medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Addresses imaging, treatment, scaffold technology, the use of stem cells to generate insulin, 3D printing, and more Offers an update on the progress of regenerative medicine research aimed at beta cell replacement for the treatment of diabetes
Author : Giuseppe Orlando
Publisher : Academic Press
ISBN 13 : 0128148349
Total Pages : 890 pages
Book Rating : 4.1/5 (281 download)
Download or read book Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas written by Giuseppe Orlando and published by Academic Press. This book was released on 2019-11-09 with total page 890 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 1, sets a new standard in transplant and regenerative medicine. The book details the-state-of-the-art in modern whole pancreas and islet transplantation, including donor selection, immunosuppression, complications, allograft pathology, and more. As regenerative medicine is changing the premise of solid organ transplantation, this volume catalogs the technologies being developed and the methods being implemented to bioengineer or regenerate the endocrine pancreas in order to more effectively treat diabetes. Edited and authored by unparalleled leaders in the field, this new volume argues for a much needed synergy between organ transplantation and regenerative medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Includes sections that address donor selection, immunosuppression, complications, allograft pathology, and more Offers an update on the progress of regenerative medicine research aimed at beta cells replacement in the treatment of diabetes
