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Immune And Receptor Assays In Theory And Practice
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Book Synopsis Immune and Receptor Assays in Theory and Practice by : Patrick Englebienne
Download or read book Immune and Receptor Assays in Theory and Practice written by Patrick Englebienne and published by CRC Press. This book was released on 1999-12-28 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past ten years, employment of immuno- and receptor- assays has grown dramatically. Now used in the pharmaceutical industry for automated screening programs, in the agro-food industry for on-line processing control and food adulteration detection, and in clinical laboratories, they are fully integrated analytical tools. However, the literature often covers only one type of assay or just one of the many systems available. Immune and Receptor Assays in Theory and Practice gathers and organizes the available information to help you establish the best assay for your application. This composite presents the fundamentals of both techniques and introduces practical examples of equation use, antibody and receptor purification, antigen labeling, immunization, and establishment of antibodies for long-term storage. It contrasts the many different assay designs and addresses market trends as the context for developing immuno-assay goals. In addition, this volume summarizes the biochemical and physical properties involved in antibody- and receptor-ligand interactions and reagent manufacture. This is the first, single-volume synthesis of both immuno- and receptor-assays. With theoretical background and practical examples, Immune and Receptor Assays in Theory and Practice allows you to base your experiment on proven techniques, components, and applications for the most reliable results.
Book Synopsis Chronic Fatigue Syndrome by : Patrick Englebienne
Download or read book Chronic Fatigue Syndrome written by Patrick Englebienne and published by CRC Press. This book was released on 2002-02-27 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Fatigue Syndrome (CFS) is a complex, debilitating disorder, yet few current scientific biomedical books are available on the subject. The nonspecific symptoms, lack of diagnostic tests, and uncertainty as to the cause or causes of CFS make the disease that much more baffling. Chronic Fatigue Syndrome: A Biological Approach represents a monu
Book Synopsis Development and Application of Biomarkers by : Roger L. Lundblad
Download or read book Development and Application of Biomarkers written by Roger L. Lundblad and published by CRC Press. This book was released on 2016-04-19 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: First introduced to biomedical research in 1980, the term biomarker has taken on a life of its own in recent years and has come to mean a number of things. In biomedical science, biomarker has evolved to most commonly mean a characteristic that can be used either as a diagnostic or a prognostic, but most significantly as a screening indicator for p
Download or read book Phage Display written by Tim Clackson and published by OUP Oxford. This book was released on 2004-03-04 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book is designed to enable researchers to design and undertake all aspects of a phage display project, from designing an experimental strategy and constructing a library to performing selections and analyzing the results.All of the protocols and chapters are extensively cross-referenced, allowing readers to move beyond the specific examples provided in order to customize the procedures for their own protein or selection system of interest. Phage Display is an up-to-date, comprehensive and integrated experimental guide to the technique, which is essential reading for anyone currently using, or wishing to use the technique for basic research and drug discovery.
Book Synopsis Biotechnology of Plasma Proteins by : Roger L. Lundblad
Download or read book Biotechnology of Plasma Proteins written by Roger L. Lundblad and published by CRC Press. This book was released on 2012-08-08 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fractionation of human blood plasma can be considered to be a mature industry, with the basic technology, alcohol fractionation, dating back at least to the 1940s. Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to the development of recombinant therapeutic proteins. Discussing the role of plasma proteins in current biotechnology, Biotechnology of Plasma Proteins describes the protein composition of human plasma, the fractionation of plasma to obtain therapeutic proteins, and the analysis of these products. It delineates the path from plasma products to recombinant products, and highlights products from albumin, intravenous immunoglobins, and coagulation. It offers a comprehensive review of current techniques for the analysis of proteins including electrophoresis, chromatography, spectrophotometry, mass spectrometry, and updates not published since 1975. Key Topics Protein Composition of Plasma Proteomic methods for plasma protein analysis Plasma protein biomarkers Validation of biomarkers Assays for plasma biomarkers Methods for the Analysis of Protein Products Assay development and validation Electrophoresis Chromatography Immunoassay Mass spectrometry Raman spectroscopy Plasma Fractionation: Historical and Modern Methods Development of Cohn alcohol fractionation Industrial methods Development of chromatographic methods Plasma Protein Products of Therapeutic Value Albumin Intravenous immunoglobulin Coagulation products Growth factors Wound management
Book Synopsis Recognition of Carbohydrates in Biological Systems, Part A: General Procedures by : Y. C. Lee
Download or read book Recognition of Carbohydrates in Biological Systems, Part A: General Procedures written by Y. C. Lee and published by Elsevier. This book was released on 2003-09-15 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition of carbohydrates in biological systems has been gaining more and more attention in recent years. Although methodology for studying recognition has been developing, there is no volume that covers the wide area of methodology of carbohydrate recognition. This volume, Recognition of Carbohydrates in Biological Systems, Part A: General Procedures, and its companion, Volume 363, present state-of-the-art methodologies, as well as the most recent biological observations in this area. Covers the isolation/synthesis of substances used in studying interactions involving carbohydrates Discussed the methodology for measuring such interactions Biological roles for such interactions are also covered
Book Synopsis Application of Solution Protein Chemistry to Biotechnology by : Roger L. Lundblad
Download or read book Application of Solution Protein Chemistry to Biotechnology written by Roger L. Lundblad and published by CRC Press. This book was released on 2009-05-12 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the versatility of the author's science and the depth of his experience, Application of Solution Protein Chemistry to Biotechnology explores key contributions that protein scientists can make in the development of products that are both important and commercially viable, and provides them with tools and information required for successfu
Book Synopsis Proteolysis in the Interstitial Space by : Salvatore V. Pizzo
Download or read book Proteolysis in the Interstitial Space written by Salvatore V. Pizzo and published by CRC Press. This book was released on 2016-08-19 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most clinical laboratory tests utilize interstitial and extravascular such as blood, urine, cerebral spinal fluid (CSF), and saliva. For example, CSF is monitored in the context of cancer for both diagnostic and therapeutic reasons. And yet, our understanding of the makeup of interstitial fluids, their relationships to disease, as well as their commercial importance in therapeutics and diagnostics remains rudimentary. Although sometimes perceived as static, interstitial and extravascular fluids are surprisingly dynamic. More than half of serum albumin is in the extravascular space. These fluids move rapidly between the intravascular and extravascular spaces - one entire plasma volume is exchanged very nine hours. In the first half of the book, the authors cover fundamental concepts of interstitial fluids, including their composition and function. They then further review the mechanisms by which interstitial fluids are regulated, characterizing the importance of hyaluronan – a major constituent of interstitial spaces and an a component of synovial fluid; and, outlining the regulation of proteolysis in the interstitial space. In the second half of the book, the authors focus on the coagulation system. This system has been studied extensively in the context of vascular spaces. But many of its components exist in the interstitial spaces. Chapters are devoted to the fibrinolytic system, kallikrein, matrix metalloproteinases, coagulation factors, and protease inhibitors – all are interstitial. By covering a unique array of topics with broad application to biomedical scientists, this book expands our understanding of the importance of interstitial spaces and the fluids that move through and reside in this extravascular environment.
Book Synopsis Evaluating Endocrine Disruption in Receiving Waters by : P. V. Cline
Download or read book Evaluating Endocrine Disruption in Receiving Waters written by P. V. Cline and published by IWA Publishing. This book was released on 2003-01-01 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, concerns have been raised that low concentrations of chemicals may alter the normal functions of the endocrine system, resulting in potentially significant adverse effects on growth, reproduction, and/or development. For domestic wastewater discharges to surface water bodies, estrogenic activity of effluents has been suggested by chemical analysis, biomarkers, and /or in vitro assays. Chemical Measurements. Using sensitive analytical techniques, natural or synthetic hormones and chemicals that mimic estrogen, have been detected in some domestic wastewater effluents and associated watersheds at low concentrations. Biomarkers. Several studies have demonstrated physiological changes in fish that may be attributed to exposure to estrogenic compounds. These include the presence of vitellogenin protein in male fish and/or intersex conditions. In vitro assays. The Yeast Estrogen Screen (YES) has been used to characterize estrogenicity of effluents, influents, biosolids and surface waters. This two-year WERF project explored approaches to evaluate the potential for biomarker formation as a result of effluent exposures, and the subsequent relevance of the emerging assays and physiological measurements on potential adverse impacts to individuals or populations of fish in the receiving streams. The endocrine system is complex, and many factors can influence the physiological measurements, including methods, sex, age, reproductive status, seasonal and circadian rhythms, diet, temperature, etc. and produce transient changes in physiology but no significant effect on the individual.
Book Synopsis Environmental Health Perspectives by :
Download or read book Environmental Health Perspectives written by and published by . This book was released on 2000 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Frontiers in Drug Design and Discovery by : Atta-ur- Rahman
Download or read book Frontiers in Drug Design and Discovery written by Atta-ur- Rahman and published by Bentham Science Publishers. This book was released on 2010-12-13 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Frontiers in Drug Design and Discovery" is an Ebook series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery inclu
Book Synopsis Biochemistry and Molecular Biology Compendium by : Roger L. Lundblad
Download or read book Biochemistry and Molecular Biology Compendium written by Roger L. Lundblad and published by CRC Press. This book was released on 2019-11-11 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an accessible resource offering practical information not found in more database-oriented resources. The first chapter lists acronyms with definitions, and a glossary of terms and subjects used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. There follows chapters on chemicals employed in biochemistry and molecular biology, complete with properties and structure drawings. Researchers will find this book to be a valuable tool that will save them time, as well as provide essential links to the roots of their science. Key selling features: Contains an extensive list of commonly used acronyms with definitions Offers a highly readable glossary for systems and techniques Provides comprehensive information for the validation of biotechnology assays and manufacturing processes Includes a list of Log P values, water solubility, and molecular weight for selected chemicals Gives a detailed listing of protease inhibitors and cocktails, as well as a list of buffers
Book Synopsis Potato Breeding: Theory and Practice by : John E. Bradshaw
Download or read book Potato Breeding: Theory and Practice written by John E. Bradshaw and published by Springer Nature. This book was released on 2021-04-09 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: The potato (Solanum tuberosum) is the world’s fourth most important food crop after maize, rice and wheat with 377 million tonnes fresh-weight of tubers produced in 2016 from 19.2 million hectares of land, in 163 countries, giving a global average yield of 19.6 t ha-1 (http://faostat.fao.org). About 62% of production (234 million tonnes) was in Asia (191), Africa (25) and Latin America (18) as a result of steady increases in recent years, particularly in China and India. As a major food crop, the potato has an important role to play in the United Nations “2030 Agenda for Sustainable Development” which started on 1 January 2016 (http://faostat.fao.org). By 2030 the aim is to “ensure access by all people, in particular the poor and people in vulnerable situations, including infants, to safe, nutritious and sufficient food all year round”. By then, the world population is expected to reach 8.5 billion and continue to increase to 9.7 billion in 2050. For potatoes, the need is to increase production and improve nutritional value during a period of climate change, a key aspect of which will be the breeding of new cultivars for a wide range of target environments and consumers. The aim of the book is to help this endeavour by providing detailed information in three parts on both the theory and practice of potato breeding. Part I deals with the history of potato improvement and with potato genetics. Part II deals with breeding objectives, divided into improving yield, quality traits and resistance to the most important diseases and pests of potatoes. Part III deals with breeding methods: first, the use of landraces and wild relatives of potato in introgression breeding, base broadening and population improvement; second, breeding clonally propagated cultivars as a way to deliver potato improvement to farmers’ fields; third, as an alternative, breeding potato cultivars for propagation through true potato seed; and fourth, gene editing and genetic transformation as ways of making further improvements to already successful and widely grown cultivars. Included are marker-assisted introgression and selection of specific alleles, genomic selection of many unspecified alleles and diploid F1 hybrid breeding.
Book Synopsis Immunochemistry of Solid-Phase Immunoassay by : John E. Butler
Download or read book Immunochemistry of Solid-Phase Immunoassay written by John E. Butler and published by CRC Press. This book was released on 1991-07-23 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunochemistry of Solid-Phase Immunoassay fills a niché in the field of immunoassay and immunology. Although solid-phase immunoassay constitutes a major technology in biology and medicine, there is no comprehensive source devoted to the immunochemical principles involved. As a result, this book will benefit students, technicians, and researchers who use this technology, as well as immunodiagnostic and biotech companies who develop the technology. The book is not a methods manual; instead, it incorporates the concepts, data, and opinions of more than 25 investigators working in this field. Topics discussed include: the chemistry of solid-phases, the behavior or antibodies and antigens on solid phases, membrane solid-phases, reaction kinetics, antigen quantitation, enzyme systems, photophysics, immunochemical considerations in data analyses, multianalyte assays and occupancy concepts, antibody quantitation, streptavidin, a review of data analysis software, and solid-phase peptide immunoassay.
Book Synopsis A History of Immunology by : Arthur M. Silverstein
Download or read book A History of Immunology written by Arthur M. Silverstein and published by Academic Press. This book was released on 2009-05-30 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an immunologist, this book traces the concept of immunity from ancient times up to the present day, examining how changing concepts and technologies have affected the course of the science. It shows how the personalities of scientists and even political and social factors influenced both theory and practice in the field. With fascinating stories of scientific disputes and shifting scientific trends, each chapter examines an important facet of this discipline that has been so central to the development of modern biomedicine. With its biographical dictionary of important scientists and its lists of significant discoveries and books, this volume will provide the most complete historical reference in the field. • Written in an elegant style by long-time practicing immunologist • Discusses the changing theories and technologies that guided the field • Tells of the exciting disputes among prominent scientists • Lists all the important discoveries and books in the field • Explains in detail the many Nobel prize-winning contributions of immunologists
Book Synopsis Proceedings of the National Academy of Sciences of the United States of America by : National Academy of Sciences (U.S.).
Download or read book Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.). and published by . This book was released on 2007 with total page 1340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Magnetic Biosensor Using a High Transition Temperature SQUID by : Helene Lila Grossman
Download or read book Magnetic Biosensor Using a High Transition Temperature SQUID written by Helene Lila Grossman and published by . This book was released on 2003 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
