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Immediate Early Genes In Sensory Processing Cognitive Performance And Neurological Disorders
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Book Synopsis Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders by : Raphael Pinaud
Download or read book Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders written by Raphael Pinaud and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a compilation of the most up-to-date literature on the topic of immediate early genes (IEGs). It reviews and details experiments and theories that challenge the reader to expand their view on how IEG research is currently being used to advance our understanding of static and active brain circuits. In addition, the book explores roles of IEGs in clinical neuropathology.
Book Synopsis Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction by : L. Kaczmarek
Download or read book Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction written by L. Kaczmarek and published by Gulf Professional Publishing. This book was released on 2002-07-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: That molecular neurobiology has become a dominant part of neuroscience research can be credited to the discovery of inducible gene expression in the brain and spinal cord. This volume deals with genes, whose expression patterns in the vertebrate central nervous system were the first to be revealed and then the most extensively investigated over the last 15 years. Immediate early genes (IEG) and their protein products, especially those acting as regulators of transcription (inducible transcription factors, ITF) have proven to be very valuable tools in functional neuroanatomy and neurophysiology, as they are rapidly and transiently induced in specific neurons in response to various modes of stimulation. Thus, they have been used to map neuronal populations selectively responsive to a variety of conditions, such as sensory and learning experience, electrical stimulation of specific circuits, seizures, and neurodegeneration. This single volume, written by the most prominent authors in the field, brings together for the first time information about the most widely studied IEG/ITF in a whole variety of phenomena of neuronal activation. It starts with a critical appraisal of the technologies employed for the studies on gene, protein, and transcription factor activity in the nervous system. Several chapters present exhaustive examples of expression patterns of the ITF in "vocal" avian brain, mammalian brain sensory regions, areas involved in regulation of circadian rhythms, and the spinal cord. The next parts cover functional and regular aspects of individual IEG/ITF expression: c-fos in learning and memory, c-jun and others in neuropathology and neuronal stress responses, Elk-1, egr family, and CREB in neuronal plasticity and learning. This volume will be useful as a major reference on this topic. Furthermore, it attempts to unravel the seemingly overwhelming complexity of the phenomena of gene expression in the central nervous system.
Book Synopsis Brain Aromatase, Estrogens, and Behavior by : Jacques Balthazart
Download or read book Brain Aromatase, Estrogens, and Behavior written by Jacques Balthazart and published by Oxford University Press. This book was released on 2012-09-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well known that the class of steroid hormones known as estrogens have powerful effects on organs related to reproduction such as the uterus and the breast. What is less well known is that estrogens also profoundly modulate brain function and behavior. Estrogens, such as estradiol, can occur in brain as the result of ovarian secretion of the hormone into the blood that then finds its way to the brain. In male vertebrates, the testes secrete androgens, such as testosterone, into the blood and this class of steroid hormones can be converted into estrogens in the brain via the action of the enzyme aromatase which is expressed in the male brain in many species. Finally estradiol can be synthesized de novo from cholesterol as it has been shown in a variety of species that all the enzymes required to synthesize estrogens are expressed in the brain. This book collects chapters by experts in the field that considers, how estradiol is synthesized in the brain and what its effects are on a variety of behaviors. Special attention is paid to the enzyme aromatase that is distributed in discrete regions of the brain and is highly regulated in a sex specific and seasonal specific manner. Recently it has become clear that estrogens can act in the brain at two very different time scales, one is rather long lasting (days to weeks) and involves the modulation of gene transcription by the hormone-receptor complex. A second mode of action is much quicker and involves the action of estrogens on cell membranes that can result in effects on second messenger systems and ultimately behavior within minutes. Thus this book highlights novel views of estrogen action that are still under-appreciated namely that estrogens have significant effects on the male brain and that they can act on two very different times scales. This volume will be of interest to both basic researchers and clinicians interested in the action of estrogens.
Book Synopsis The Role of Immediate Early Genes in Neuropsychiatric Illness by : Amelia L. Gallitano
Download or read book The Role of Immediate Early Genes in Neuropsychiatric Illness written by Amelia L. Gallitano and published by Frontiers Media SA. This book was released on 2020-03-30 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg
Book Synopsis Rapid Eye Movement Sleep by : Birendra N. Mallick
Download or read book Rapid Eye Movement Sleep written by Birendra N. Mallick and published by Cambridge University Press. This book was released on 2011-07-14 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spanning over half a century of investigation into Rapid Eye Movement (REM) sleep, this volume provides comprehensive coverage of a broad range of topics in REM sleep biology. World renowned researchers and experts are brought together to discuss past and current research and to set the foundation for future developments. Key topics are covered in six sections from fundamental topics (historical context and general biology) to cutting-edge research on neuronal regulation, neuroanatomy and neurochemistry, functional significance and disturbance in the REM sleep generating mechanism. A reference source for all aspects of REM sleep research, it also incorporates chapters on neural modelling, findings from non-human species and interactions between brain regions. This is an invaluable resource, essential reading for all involved in sleep research and clinical practice.
Book Synopsis Essential Leadership by : Daniel Augusto Motta
Download or read book Essential Leadership written by Daniel Augusto Motta and published by BMI Editora e Publicações LTDA. This book was released on 2017-11-10 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: To the writer, Essential Leadership in based on three pillars —Personal Excellence, Individual Essence and Organization Transformation. Within this framework, a leader must understand, define, and impact an organization's strategy, seeing to its development and survival. Organizational objectives must be clear and aligned, and this is the mission of every leader, whatever the structure's size and complexity. To this end, leaders need to be aware of their three vectors —Adherence to Beliefs and Values, Consistent Productivity and Emotional Bond. ELOS Essential Leadership Skills for Organizational Strategy methodology is based on six elos, and each one has four drivers. The elos that need to be fully understood and cultivated are Competitive Environment, Value Proposition, Organization Essence, Strategic Execution, Essential Leadership and Performance Catalysts. This book also contains a rich, in-depth analysis of Europe's, China's and India's past, and points out to leaders the direction and the steps needed to redefine and achieve organizational goals. Forewords by two top executives and testimonials from six others are a testament to Motta's theory.
Book Synopsis From Neurons to Neighborhoods by : National Research Council
Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Book Synopsis Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics by : Carl Faingold
Download or read book Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics written by Carl Faingold and published by Academic Press. This book was released on 2013-12-26 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Book Synopsis Advanced Imaging Methods in Neuroscience by : João O. Malva
Download or read book Advanced Imaging Methods in Neuroscience written by João O. Malva and published by Frontiers Media SA. This book was released on 2022-01-11 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Highly Sensitive Brain by : Bianca P. Acevedo
Download or read book The Highly Sensitive Brain written by Bianca P. Acevedo and published by Academic Press. This book was released on 2020-05-16 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Highly Sensitive Brain is the first handbook to cover the science, measurement, and clinical discussion of sensory processing sensitivity (SPS), a trait associated with enhanced responsivity, awareness, depth-of-processing and attunement to the environment and other individuals. Grounded in theoretical models of high sensitivity, this volume discusses the assessment of SPS in children and adults, as well as its health and social outcomes. This edition also synthesizes up-to-date research on the biological mechanisms associated with high sensitivity, such as its neural and genetic basis. It also discusses clinical issues related to SPS and seemingly-related disorders such as misophonia, a hyper-sensitivity to specific sounds. In addition, to practical assessment of SPS embedded throughout this volume is discussion of the biological basis of SPS, exploring why this trait exists and persists in humansand other species. The Highly Sensitive Brain is a useful handbook and may be of special interest to clinicians, physicians, health-care workers, educators, and researchers. Presents a neurobiological perspective of sensory processing sensitivity (SPS) Provides assessment criteria and measurement tools for highly sensitive children and adults Discusses the health and social outcomes of being highly sensitive in children and adults Examines clinical issues related to high sensitivity Offers practical applications and a future vision for integrating high sensitivity in our society
Book Synopsis The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy by : Udo Rüb
Download or read book The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy written by Udo Rüb and published by Springer. This book was released on 2015-09-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.
Book Synopsis Lateralized Brain Functions: Methods in Human and Non-Human Species by : Lesley J. Rogers
Download or read book Lateralized Brain Functions: Methods in Human and Non-Human Species written by Lesley J. Rogers and published by Neuromethods. This book was released on 2019-02 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Associative Memory Cells: Basic Units of Memory Trace by : Jin-Hui Wang
Download or read book Associative Memory Cells: Basic Units of Memory Trace written by Jin-Hui Wang and published by Springer Nature. This book was released on 2019-09-10 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on associative memory cells and their working principles, which can be applied to associative memories and memory-relevant cognitions. Providing comprehensive diagrams, it presents the author's personal perspectives on pathology and therapeutic strategies for memory deficits in patients suffering from neurological diseases and psychiatric disorders. Associative learning is a common approach to acquire multiple associated signals, including knowledge, experiences and skills from natural environments or social interaction. The identification of the cellular and molecular mechanisms underlying associative memory is important in furthering our understanding of the principles of memory formation and memory-relevant behaviors as well as in developing therapeutic strategies that enhance memory capacity in healthy individuals and improve memory deficit in patients suffering from neurological disease and psychiatric disorders. Although a series of hypotheses about neural substrates for associative memory has been proposed, numerous questions still need to be addressed, especially the basic units and their working principle in engrams and circuits specific for various memory patterns. This book summarizes the developments concerning associative memory cells reported in current and past literature, providing a valuable overview of the field for neuroscientists, psychologists and students.
Book Synopsis Progress of Theoretical Physics by :
Download or read book Progress of Theoretical Physics written by and published by . This book was released on 2008 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cognitive Enhancement in Schizophrenia and Related Disorders by : Matcheri Keshavan
Download or read book Cognitive Enhancement in Schizophrenia and Related Disorders written by Matcheri Keshavan and published by Cambridge University Press. This book was released on 2019-03-21 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide on how to assess and treat schizophrenia and related disorders using cognitive rehabilitation.
Book Synopsis Invertebrate Learning and Memory by : Martin Giurfa
Download or read book Invertebrate Learning and Memory written by Martin Giurfa and published by Elsevier Inc. Chapters. This book was released on 2013-06-18 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: The behavior of insects transcends elementary forms of adaptive responding to environmental changes. We discuss examples of exploration, instrumental and observational learning, expectation, learning in a social context, and planning of future actions. We show that learning about sensory cues allows insects to transfer flexibly their responses to novel stimuli attaining thereby different levels of complexity, from basic generalization to categorization and concept learning consistent with rule extraction. We argue that updating of existing memories requires multiple forms of memory processing. A key element in these processes is working memory, an active form of memory considered to allow evaluation of actions on the basis of expected outcome. We discuss which of these cognitive faculties can be traced to specific neural processes and how they relate to the overall organization of the insect brain.
