The Theory and Practice of 3D PET

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Publisher : Springer Science & Business Media
ISBN 13 : 9401734755
Total Pages : 180 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis The Theory and Practice of 3D PET by : B. Bendriem

Download or read book The Theory and Practice of 3D PET written by B. Bendriem and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of 3D methodology has recently been receiving increasing attention at many PET centres, and this monograph is an attempt to provide a state-of-the-art review of this methodology, covering 3D reconstruction methods, quantitative procedures, current tomography performance, and clinical and research applications. No such review has been available until now to assist PET researchers in understanding and implementing 3D methodology, and in evaluating the performance of the available imaging technology. In all the chapters, the subject matter is treated in sufficient depth to appeal equally to the physicist or engineer who wishes to establish the methodology, and to PET investigators with experience in 2D PET who wish to familiarize themselves with the concepts and advantages of 3D, and to be made aware of the pitfalls.

Image Reconstruction for High-resolution PET

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (66 download)

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Book Synopsis Image Reconstruction for High-resolution PET by : Guillem Pratx

Download or read book Image Reconstruction for High-resolution PET written by Guillem Pratx and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular imaging can interrogate subtle molecular disease signatures non-invasively in living subjects. Positron emission tomography (PET), one particular molecular imaging modality, is able to sense molecular signals deep within tissue. Although PET is well suited for imaging signals associated with cancerous lesions in humans, it is still unable to resolve very small (

Novel Spatiotemporal Image Reconstruction for High Resolution PET Imaging in Neuroscience

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (17 download)

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Book Synopsis Novel Spatiotemporal Image Reconstruction for High Resolution PET Imaging in Neuroscience by : Georgios Angelis

Download or read book Novel Spatiotemporal Image Reconstruction for High Resolution PET Imaging in Neuroscience written by Georgios Angelis and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Novel PET Systems and Image Reconstruction with Actively Controlled Geometry

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Publisher :
ISBN 13 :
Total Pages : 124 pages
Book Rating : 4.:/5 (13 download)

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Book Synopsis Novel PET Systems and Image Reconstruction with Actively Controlled Geometry by : Ke Li (Electrical engineer)

Download or read book Novel PET Systems and Image Reconstruction with Actively Controlled Geometry written by Ke Li (Electrical engineer) and published by . This book was released on 2017 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron Emission Tomography (PET) provides in vivo measurement of imaging ligands that are labeled with positron emitting radionuclide. Since its invention, most PET scanners have been designed to have a group of gamma ray detectors arranged in a ring geometry, accommodating the whole patient body. Virtual Pinhole PET incorporates higher resolution detectors being placed close to the Region-of-Interest (ROI) within the imaging Field-of-View (FOV) of the whole-body scanner, providing better image resolution and contrast recover. To further adapt this technology to a wider range of diseases, we proposed a second generation of virtual pinhole PET using actively controlled high resolution detectors integrated on a robotic arm. When the whole system is integrated to a commercial PET scanner, we achieved positioning repeatability within 0.5 mm. Monte Carlo simulation shows that by focusing the high-resolution detectors to a specific organ of interest, we can achieve better resolution, sensitivity and contrast recovery.In another direction, we proposed a portable, versatile and low cost PET imaging system for Point-of-Care (POC) applications. It consists of one or more movable detectors in coincidence with a detector array behind a patient. The movable detectors make it possible for the operator to control the scanning trajectory freely to achieve optimal coverage and sensitivity for patient specific imaging tasks. Since this system does not require a conventional full ring geometry, it can be built portable and low cost for bed-side or intraoperative use. We developed a proof-of-principle prototype that consists of a compact high resolution silicon photomultiplier detector mounted on a hand-held probe and a half ring of conventional detectors. The probe is attached to a MicroScribe device, which tracks the location and orientation of the probe as it moves. We also performed Monte Carlo simulations for two POC PET geometries with Time-of-Flight (TOF) capability. To support the development of such PET systems with unconventional geometries, a fully 3D image reconstruction framework has been developed for PET systems with arbitrary geometry. For POC PET and the second generation robotic Virtual Pinhole PET, new challenges emerge and our targeted applications require more efficiently image reconstruction that provides imaging results in near real time. Inspired by the previous work, we developed a list mode GPU-based image reconstruction framework with the capability to model dynamically changing geometry. Ordered-Subset MAP-EM algorithm is implemented on multi-GPU platform to achieve fast reconstruction in the order of seconds per iteration, under practical data rate. We tested this using both experimental and simulation data, for whole body PET scanner and unconventional PET scanners. Future application of adaptive imaging requires near real time performance for large statistics, which requires additional acceleration of this framework.

Pragmatic Image Reconstruction for High Resolution PET Scanners

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Publisher :
ISBN 13 :
Total Pages : 258 pages
Book Rating : 4.:/5 (55 download)

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Book Synopsis Pragmatic Image Reconstruction for High Resolution PET Scanners by : Ki Sung Lee

Download or read book Pragmatic Image Reconstruction for High Resolution PET Scanners written by Ki Sung Lee and published by . This book was released on 2003 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Emission Tomography

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Publisher : Elsevier
ISBN 13 : 0080521878
Total Pages : 597 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Emission Tomography by : Miles N. Wernick

Download or read book Emission Tomography written by Miles N. Wernick and published by Elsevier. This book was released on 2004-12-07 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: PET and SPECT are two of today's most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the world's fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging.*Contains thorough tutorial treatments, coupled with coverage of advanced topics*Three of the four holders of the prestigious Institute of Electrical and Electronics Engineers Medical Imaging Scientist Award are chapter contributors*Include color artwork

High Resolution Image Reconstruction Method for a Double-plane PET System with Changeable Spacing *Supported by Knowledge Innovation Project of The Chinese Academy of Sciences (KJCX2-EW-N06).

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (15 download)

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Book Synopsis High Resolution Image Reconstruction Method for a Double-plane PET System with Changeable Spacing *Supported by Knowledge Innovation Project of The Chinese Academy of Sciences (KJCX2-EW-N06). by :

Download or read book High Resolution Image Reconstruction Method for a Double-plane PET System with Changeable Spacing *Supported by Knowledge Innovation Project of The Chinese Academy of Sciences (KJCX2-EW-N06). written by and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Breast-dedicated positron emission tomography (PET) imaging techniques have been developed in recent years. Their capacities to detect millimeter-sized breast tumors have been the subject of many studies. Some of them have been confirmed with good results in clinical applications. With regard to biopsy application, a double-plane detector arrangement is practicable, as it offers the convenience of breast immobilization. However, the serious blurring effect of the double-plane PET, with changeable spacing for different breast sizes, should be studied. We investigated a high resolution reconstruction method applicable for a double-plane PET. The distance between the detector planes is changeable. Geometric and blurring components were calculated in real-time for different detector distances, and accurate geometric sensitivity was obtained with a new tube area model. Resolution recovery was achieved by estimating blurring effects derived from simulated single gamma response information. The results showed that the new geometric modeling gave a more finite and smooth sensitivity weight in the double-plane PET. The blurring component yielded contrast recovery levels that could not be reached without blurring modeling, and improved visual recovery of the smallest spheres and better delineation of the structures in the reconstructed images were achieved with the blurring component. Statistical noise had lower variance at the voxel level with blurring modeling at matched resolution, compared to without blurring modeling. In distance-changeable double-plane PET, finite resolution modeling during reconstruction achieved resolution recovery, without noise amplification.

Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy

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Publisher : Springer
ISBN 13 : 4431558942
Total Pages : 328 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy by : Yuji Kuge

Download or read book Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy written by Yuji Kuge and published by Springer. This book was released on 2016-04-02 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled “Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. “The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medical therapy and drug development, and was also a good opportunity to discuss the future perspective of nuclear medicine and molecular imaging by worldwide leaders in the field. Molecular imaging technologies have been rapidly developed worldwide in recent years. Among those developments, nuclear medicine has come to play an important role in quantitative analysis of biological process in vivo as well as in wide clinical use. With the current progress of nuclear medicine and molecular imaging, this modality has been applied for treatment monitoring and predicting its outcome with the use of optimal imaging biomarkers and suitable quantitative analysis. Truly, a new era has arrived with clinical use of nuclear medicine and molecular imaging for personalized medicine. This volume will benefit a wide variety of researchers in life science including those working in drug development, molecular imaging, and medical therapy as well as physicians who utilize diagnostic imaging.

Positron Emission Tomography

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Publisher : Springer Science & Business Media
ISBN 13 : 1846280079
Total Pages : 381 pages
Book Rating : 4.8/5 (462 download)

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Book Synopsis Positron Emission Tomography by : Dale L. Bailey

Download or read book Positron Emission Tomography written by Dale L. Bailey and published by Springer Science & Business Media. This book was released on 2006-07-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. In recent years, PET has moved from high-end research imaging tool used by the highly specialized to an essential component of clinical evaluation in the clinic, especially in cancer management. Previously being the realm of scientists, this book explains PET instrumentation, radiochemistry, PET data acquisition and image formation, integration of structural and functional images, radiation dosimetry and protection, and applications in dedicated areas such as drug development, oncology, and gene expression imaging. The technologist, the science, engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will find this book invaluable. This book is primarily repackaged content from the Basic Science section of the 'big' Valk book on PET. It contains new, completely revised and unchanged chapters covering the "basic sciences" section of the main book - total 18 chapters: 2 new (chapters 1, 16) 8 completely revised (chapters 4, 5, 8, 13, 14, 15, 17, 18) 3 minor corrections (chapters 2, 6, 11) 5 unchanged (chapters 3, 7, 9, 10, 12)

Mathematical Methods in Image Reconstruction

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Publisher : SIAM
ISBN 13 : 0898716225
Total Pages : 226 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis Mathematical Methods in Image Reconstruction by : Frank Natterer

Download or read book Mathematical Methods in Image Reconstruction written by Frank Natterer and published by SIAM. This book was released on 2001-01-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with a superior understanding of the mathematical principles behind imaging.

Image Reconstruction for a High Resolution PET-insert Scanner

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Publisher :
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.:/5 (233 download)

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Book Synopsis Image Reconstruction for a High Resolution PET-insert Scanner by : Debashish Pal

Download or read book Image Reconstruction for a High Resolution PET-insert Scanner written by Debashish Pal and published by . This book was released on 2008 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Physics of PET and SPECT Imaging

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Publisher : CRC Press
ISBN 13 : 1315356783
Total Pages : 519 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Physics of PET and SPECT Imaging by : Magnus Dahlbom

Download or read book Physics of PET and SPECT Imaging written by Magnus Dahlbom and published by CRC Press. This book was released on 2017-02-17 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: PET and SPECT imaging has improved to such a level that they are opening up exciting new horizons in medical diagnosis and treatment. This book provides a complete introduction to fundamentals and the latest progress in the field, including an overview of new scintillator materials and innovations in photodetector development, as well as the latest system designs and image reconstruction algorithms. It begins with basics of PET and SPECT physics, followed by technology advances and computing methods, quantitative techniques, multimodality imaging, instrumentation, pre-clinical and clinical imaging applications.

Residual Correction Algorithms for Statistical Image Reconstruction in Positron Emission Tomography

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Publisher :
ISBN 13 : 9781124025315
Total Pages : pages
Book Rating : 4.0/5 (253 download)

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Book Synopsis Residual Correction Algorithms for Statistical Image Reconstruction in Positron Emission Tomography by : Lin Fu

Download or read book Residual Correction Algorithms for Statistical Image Reconstruction in Positron Emission Tomography written by Lin Fu and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron emission tomography (PET) is a radionuclide imaging modality that plays important roles in visualizing, targeting, and quantifying functional processes in vivo. High-resolution and quantitative PET images are reconstructed by solving large-scale inverse problems with iterative methods that incorporate accurate physics and noise modeling of the imaging process. The computation demands of PET image reconstruction are rapidly increasing as higher-resolution detectors, larger imaging field-of-view, and dynamic or adaptive data acquisition modes are being adopted by modern PET scanners. The trend of the increase in the computation demands is even faster than Moore's law that describes the exponential growth in the number of transistors placed on an integrated circuit. In this project a residual correction mechanism is introduced to PET image reconstruction to create computationally efficient yet accurate tomographic reconstruction algorithms. By using residual correction, reconstruction methods are able to adopt a more simplified physical model for fast computation while retaining the accuracy of the final solution. Residual correction can accelerate existing image reconstruction packages. It allows iterative reconstruction with more accurate physical models which are currently impractical due to the high computation cost. Two illustrative applications of the residual correction approach are provided. One is image reconstruction with an object-dependent Monte Carlo based physics model. The other is image reconstruction using an ultra fast GPU-accelerated simplified geometric model.

Investigation of PET Image Reconstruction and Data Correction Techniques with Emphasis on an Accelerated Monte Carlo Simulation for Correction and Evaluation of PET

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Publisher :
ISBN 13 :
Total Pages : 574 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Investigation of PET Image Reconstruction and Data Correction Techniques with Emphasis on an Accelerated Monte Carlo Simulation for Correction and Evaluation of PET by : Clay Houghton Holdsworth

Download or read book Investigation of PET Image Reconstruction and Data Correction Techniques with Emphasis on an Accelerated Monte Carlo Simulation for Correction and Evaluation of PET written by Clay Houghton Holdsworth and published by . This book was released on 2002 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Basic Science of PET Imaging

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Publisher : Springer
ISBN 13 : 3319400703
Total Pages : 621 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Basic Science of PET Imaging by : Magdy M. Khalil

Download or read book Basic Science of PET Imaging written by Magdy M. Khalil and published by Springer. This book was released on 2016-11-07 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.

A Four-dimensional Image Reconstruction Framework for PET Under Arbitrary Geometries

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Publisher :
ISBN 13 :
Total Pages : 132 pages
Book Rating : 4.:/5 (98 download)

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Book Synopsis A Four-dimensional Image Reconstruction Framework for PET Under Arbitrary Geometries by : Aswin John Mathews

Download or read book A Four-dimensional Image Reconstruction Framework for PET Under Arbitrary Geometries written by Aswin John Mathews and published by . This book was released on 2014 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron Emission Tomography (PET) is a functional imaging modality with applications ranging from the treatment of cancer, studying neurological diseases and disease models. Virtual-Pinhole PET technology improves the image quality in terms of resolution and contrast recovery. The technology calls for having a detector with smaller crystals placed near a region of interest in a conventional whole-body PET scanner. The improvement is from the higher spatial sampling of the imaging area near the detector. A prototype half-ring PET insert built to study head-and-neck cancer imaging was extended to breast cancer imaging. We have built a prototype half-ring PET insert for head-and-neck cancer imaging applications. In the first half of this work, we extend the use of the insert to breast imaging and show that such a system provides high resolution images of breast and axillary lymph nodes while maintaining the full imaging field of view capability of a clinical PET scanner. We are focused on designing unconventional PET geometries for specific applications. A general purpose 4D PET reconstruction framework was created to estimate the radionuclide uptake in the subject. Quantitative estimation in PET requires precise modeling of PET physics. Data acquired in a PET scanner is well modeled as a Poisson counting process. Reconstruction given the forward model is implemented using MAP-OSEM. The framework is capable of reconstructing PET data under arbitrary position of the detector elements and different crystal sizes. A novel symmetry finding algorithm is created to reduce the system matrix size, without loss of resolution. The framework motivates investigation into different PET system geometries for different applications, as well as optimizing the design of PET systems. A generalized normalization procedure was developed to model unknown components. The programs are parallelized using OpenMP and MPI to run on small workstations as well as super-computing clusters. The performance of our reconstruction framework is presented through four novel and unconventional PET systems, each designed specifically for a different geometry. The Virtual-Pinhole half-ring system is a half-ring insert integrated into a Siemens Biograph-40, for head and neck imaging. The Flat-panel system is a modular insert system integrated into the Biograph-40, designed for breast cancer imaging. The MicroInsert II is the second generation full ring insert device, integrated into the MicroPET scanner to improve the resolution and contrast recovery of the MicroPET scanner. The Plant PET system is a PET system designed to image plants vertically, and integrated into a plant growth chamber. The improvement in speed/memory from symmetry finding is as high as a factor of 50 in some cases. Further improvements to the framework and state of the field are also discussed.

Statistical Tomographic Image Reconstruction Methods for Randoms-precorrected PET Measurements

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Publisher :
ISBN 13 :
Total Pages : 410 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Statistical Tomographic Image Reconstruction Methods for Randoms-precorrected PET Measurements by : Mehmet Yavuz

Download or read book Statistical Tomographic Image Reconstruction Methods for Randoms-precorrected PET Measurements written by Mehmet Yavuz and published by . This book was released on 2000 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: