Iarc Monographs On The Evaluation Of The Carcinogenic Risk Of Chemicals To Man V4 Some Aromatic Amines Hydrazine And Related Substances N Nitroso Compounds And Miscellaneous Alkylating Agents The Views Of The Iarc Working Group On The Evaluation Of The Carcinogenic Risk Of Chemicals To Man Which Met In Lyon 18 25 June 1973

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Tobacco and Public Health

Author : Peter Boyle
Publisher :
ISBN 13 : 9780198526872
Total Pages : 840 pages
Book Rating : 4.5/5 (268 download)

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Book Synopsis Tobacco and Public Health by : Peter Boyle

Download or read book Tobacco and Public Health written by Peter Boyle and published by . This book was released on 2004 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively covers the science and policy issues relevant to one of the major public health disasters of modern times. It pulls together the aetiology and burden of the myriad of tobacco related diseases with the successes and failures of tobacco control policies. The book looks at lessons learnt to help set health policy for reducing the burden of tobacco related diseases. The book also deals with the international public health policy issues which bear on control of the problem of tobacco use and which vary between continents. The editors are an international group distinguished in the field of tobacco related diseases, epidemiology, and tobacco control. The contributors are world experts drawn from the various clinical fields. This major reference text gives a unique overview of one of the major public health problems in both the developed and developing world. The book is directed at an international public health and epidemiology audience includng health economists and those interested in tobacco control.

Peroxisome Proliferation and Its Role in Carcinogenesis

Author :
Publisher : World Health Organization
ISBN 13 :
Total Pages : 104 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Peroxisome Proliferation and Its Role in Carcinogenesis by :

Download or read book Peroxisome Proliferation and Its Role in Carcinogenesis written by and published by World Health Organization. This book was released on 1995 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art consensus report on what is known about peroxisome proliferation, the mechanisms involved, and their relevance to carcinogenesis. Peroxisomes are single, membrane-limited, cytoplasmic organelles that are found in cells of animals, plants, fungi, and protozoa. Peroxisome proliferators include certain hypolipidaemic drugs, phthalate ester plasticizers, industrial solvents, herbicides, food flavours, leukotriene D4 antagonists, and hormones. Numerous studies in rats and mice have demonstrated the hepatocarcinogenic effects of peroxisome proliferators, and these compounds have been unequivocally established as carcinogens. Since humans are exposed to peroxisome proliferators to a significant extent, assessment of the adverse biological effects of this group of compounds, and particularly their potential carcinogenicity, has become an important issue. The report has two parts. The first records the consensus reached by a group of eleven experts, including several of the leading investigators in this field. Questions addressed include the mechanisms by which peroxisome proliferators exert their carcinogenic effects in rodents, the relevance of animal studies to the evaluation of carcinogenic risk in humans, and the potential use of peroxisome proliferation as a biological marker for liver cancer. The report concludes that compounds inducing peroxisome proliferation in rats and mice have little, if any, effect on human liver. The report also issues advice on the interpretation of peroxisome proliferation, demonstrated in animal studies, when evaluating the carcinogenic risk to humans. The second part consists of three background papers presented by members of the working group.

How Tobacco Smoke Causes Disease

Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide

Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher :
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by . This book was released on 1999 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Potential Industrial Carcinogens and Mutagens

Author : L. Fishbein
Publisher : Elsevier
ISBN 13 : 0080874630
Total Pages : 545 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Potential Industrial Carcinogens and Mutagens by : L. Fishbein

Download or read book Potential Industrial Carcinogens and Mutagens written by L. Fishbein and published by Elsevier. This book was released on 2011-08-30 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Potential Industrial Carcinogens and Mutagens

Autoxidation in Food and Biological Systems

Author : M.G. Simic
Publisher : Springer Science & Business Media
ISBN 13 : 1475793510
Total Pages : 652 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Autoxidation in Food and Biological Systems by : M.G. Simic

Download or read book Autoxidation in Food and Biological Systems written by M.G. Simic and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: The material presented in this book deals with basic mechanisms of free radical reactions in autoxidation processes and anitoxidant suppression of autoxidation of foods, biochemical models and biologi cal systems. Autoxidation in foods and corresponding biological effects are usually approached separately although recent mechanistic developments in the biochemistry and free radical chemistry of per oxides and their precursors tend to bring these two fields closer. Apparent ability of antioxidants in diets to reduce the inci dence of cancer has resulted in scrutiny of autoxidized products and their precursors as possibly toxic, mutagenic and carcinogenic agents. Mechanisms of any of these effects have been barely ad dressed. Yet we know now that free radicals, as esoteric as they were only a few decades ago, are being discovered in foods, biochem ical and biological systems and do play a role in the above-mentioned causalities. The purpose of the Workshop and the resulting book was to give a unifying approach towards study of beneficial and deleterious effects of autoxidation, based on rigorous scientific considerations. It is our hope that the material presented in this book will not only provide a review of the "state of the art" of autoxidation and anti oxidants, but also reflect the interaction which occurred during the Workshop between workers using model sytems, and food and biological systems.

Cigars

Author : National Cancer Institute (U.S.)
Publisher :
ISBN 13 :
Total Pages : 258 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cigars by : National Cancer Institute (U.S.)

Download or read book Cigars written by National Cancer Institute (U.S.) and published by . This book was released on 1998 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identifies upward trend in cigar use as potential serious public health problem.

Oxford Textbook of Cancer Biology

Author : Francesco Pezzella
Publisher : Oxford University Press
ISBN 13 : 0198779453
Total Pages : 505 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Oxford Textbook of Cancer Biology by : Francesco Pezzella

Download or read book Oxford Textbook of Cancer Biology written by Francesco Pezzella and published by Oxford University Press. This book was released on 2019-05-02 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.

Some Non-nutritive Sweetening Agents

Author :
Publisher :
ISBN 13 :
Total Pages : 208 pages
Book Rating : 4.:/5 (251 download)

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Book Synopsis Some Non-nutritive Sweetening Agents by :

Download or read book Some Non-nutritive Sweetening Agents written by and published by . This book was released on 1980 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Air Pathway Analysis

Author :
Publisher :
ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Air Pathway Analysis by :

Download or read book Air Pathway Analysis written by and published by . This book was released on 1993 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Review of Human Carcinogens. F. Chemical Agents and Related Occupations

Author : International Agency for Research on Cancer
Publisher : International Agency for Research on Cancer
ISBN 13 :
Total Pages : 636 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis A Review of Human Carcinogens. F. Chemical Agents and Related Occupations by : International Agency for Research on Cancer

Download or read book A Review of Human Carcinogens. F. Chemical Agents and Related Occupations written by International Agency for Research on Cancer and published by International Agency for Research on Cancer. This book was released on 2012-09-24 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 100 compiles information on tumor sites and mechanisms of carcinogenesis. About half of the agents classified in Group 1 were last reviewed more than 20 years ago, before mechanistic studies became prominent in evaluations of carcinogenicity. In addition, more recent epidemiological studies and animal cancer bioassays have demonstrated that many cancer hazards reported in earlier studies were later observed in other organs or through different exposure scenarios. Much can be learned by updating the assessments of agents that are known to cause cancer in humans. Accordingly, IARC has selected A Review of Human Carcinogensto be the topic for Volume 100. It is hoped that this volume, by compiling the knowledge accumulated through several decades of cancer research, will stimulate cancer prevention activities worldwide, and will be a valued resource for future research to identify other agents suspected of causing cancer in humans. Volume 100 was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Metals, particles, and fibres; Radiation; Personal habits and household exposures; Chemical agents and related occupations. Because the scope of Volume 100 is so broad, its Monographs are focused on key information. Each Monograph presents a description of a carcinogenic agent and how people are exposed, critical overviews of the epidemiological studies and animal cancer bioassays, and a concise review of the agent's toxicokinetics, plausible mechanisms of carcinogenesis, and potentially susceptible populations, and life-stages. Details of the design and results of individual epidemiological studies and animal cancer bioassays are summarized in tables. Short tables that highlight key results are printed in Volume 100, and more extensive tables that include all studies appear on the Monographs programe website (http://monographs.iarc.fr/). For a few well-established associations (for example, tobacco smoke and human lung cancer), it was impractical to include all studies, even in the website tables. In those instances, the rationale for inclusion or exclusion of sets of studies is given.

Cancer

Author : Vincent T. DeVita
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781744508
Total Pages : 3144 pages
Book Rating : 4.7/5 (445 download)

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Book Synopsis Cancer by : Vincent T. DeVita

Download or read book Cancer written by Vincent T. DeVita and published by Lippincott Williams & Wilkins. This book was released on 2005 with total page 3144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines molecular biologic techniques including proteomics, genomics, targeted therapies, RNA interference, cDNA arrays, and tissue arrays. This book contains sections discussing bioinformatics and societal issues in oncology, including regulatory issues, telemedicine, and international differences in oncology.

Toxicology

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (729 download)

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Book Synopsis Toxicology by :

Download or read book Toxicology written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Casarett & Doull's Essentials of Toxicology

Author : CURTIS. WATKINS KLAASSEN (JOHN.)
Publisher :
ISBN 13 : 9781259255359
Total Pages : 524 pages
Book Rating : 4.2/5 (553 download)

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Book Synopsis Casarett & Doull's Essentials of Toxicology by : CURTIS. WATKINS KLAASSEN (JOHN.)

Download or read book Casarett & Doull's Essentials of Toxicology written by CURTIS. WATKINS KLAASSEN (JOHN.) and published by . This book was released on 2015-09-16 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: