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Author : Catherine Marie Smith
Publisher :
ISBN 13 :
Total Pages : 358 pages
Book Rating : 4.:/5 (319 download)
Download or read book I. Studies Toward the Total Synthesis of Iminosugars written by Catherine Marie Smith and published by . This book was released on 2002 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 364 pages
Book Rating : 4.:/5 (94 download)
Download or read book Studies Towards the Total Synthesis of Thapsigargin written by and published by . This book was released on 1994 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sharlene Jolley
Publisher :
ISBN 13 :
Total Pages : 132 pages
Book Rating : 4.:/5 (4 download)
Download or read book Studies Toward the Total Synthesis of the Gonioheptolides written by Sharlene Jolley and published by . This book was released on 1998 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Philippe Compain
Publisher : John Wiley & Sons
ISBN 13 : 9780470517444
Total Pages : 482 pages
Book Rating : 4.5/5 (174 download)
Download or read book Iminosugars written by Philippe Compain and published by John Wiley & Sons. This book was released on 2007-10-22 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iminosugars form undoubtedly the most attractive of carbohydrate mimics reported so far. In these structures, the substitution of the endocyclic oxygen of sugars by a basic nitrogen atom leads to remarkable biological properties and raises many challenges in organic synthesis. Since the discovery of their biological activity as glycosidase inhibitors in the 1970’s, these polyvalent molecules have progressively made their way from the laboratory to the clinic. The impressive series of discoveries in the field over the past ten years indicates clearly that it is “a boom time” for iminosugar chemistry and biology. The scope of their profile as inhibitors has been extended to a number of enzymes such as phosphorylases, glycosyltransferases or metalloproteinases, and iminosugars now constitute lead compounds for the development of new therapeutic agents for a wide range of diseases including diabetes, viral infections, lysosomal storage disorders and tumor metastasis. Latest developments, from iminosugar synthesis to their use in clinical studies, are presented in this book, which contains contributions from over fifteen of the major chemists, biochemists and drug developers in this rapidly expanding field. An extensive table correlating the structures of more than 600 iminosugars of therapeutic interest with their biological activities is also included in the book and should prove particularly useful to aid with the design and the discovery of novel bioactive substances. Iminosugars: From Synthesis to Therapeutic Application provides a unique resource for academic and industrial researchers working in the field of iminosugars and glycomimetics of biological and/or therapeutic interest: organic chemists, medicinal chemists, carbohydrate chemists and medical scientists.
Author : Steven Howard Shaber
Publisher :
ISBN 13 :
Total Pages : 208 pages
Book Rating : 4.:/5 (111 download)
Download or read book Studies Directed Toward the Synthesis of Mitosenes written by Steven Howard Shaber and published by . This book was released on 1983 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ramakrishnan Chidambaram
Publisher :
ISBN 13 :
Total Pages : 458 pages
Book Rating : 4.:/5 (26 download)
Download or read book Part 1. Total Synthesis of Menaquinones 1 and 2 and Studies to Determine the Effects of Lewis Acids on the Quinone-forming Reaction. Part 2. Synthesis of Alkylidene Cyclopentenediones. Part 3. Total Synthesis of (+ - ) - Royleanone written by Ramakrishnan Chidambaram and published by . This book was released on 1989 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth Stanley Matthews
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (682 download)
Download or read book The Total Synthesis of (")-renieramycin G and Studies Toward the Synthesis of (")-lemonomycin and (")-saframycin B written by Kenneth Stanley Matthews and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Benjamin Eric Blass
Publisher :
ISBN 13 :
Total Pages : 490 pages
Book Rating : 4.:/5 (338 download)
Download or read book Studies Directed Towards the Total Synthesis of Rhizoxin written by Benjamin Eric Blass and published by . This book was released on 1994 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul John Brann
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (872 download)
Download or read book Studies Toward the Synthesis of (-)-anisomycin written by Paul John Brann and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies Towards the Total Synthesis of Lactonamycin written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marco Brito-Arias
Publisher : Springer Nature
ISBN 13 : 3030978540
Total Pages : 543 pages
Book Rating : 4.0/5 (39 download)
Download or read book Synthesis and Characterization of Glycosides written by Marco Brito-Arias and published by Springer Nature. This book was released on 2022-04-22 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition is a comprehensive and extended study about the best known approaches for preparing the main types of glycosides, covering the classic and more recent glycosylation reactions used for preparing simple and challenging glycosides currently used as potent antiviral and antineoplastic drugs, or fluorogenic substrates used for enzymatic detection in cell biology. Besides, this new edition provides more examples of the glycosidic methodologies followed for preparing complex glycoconjugates such as glycoproteins and glycosphingolipids and gangliosides used as adjuvants or as synthetic vaccines candidates. Also, additional mechanistic evidence is presented for better understanding of the glycosylation reaction, trying to identify the variables mainly depending on protecting and leaving groups, as well as catalyst and reaction condition which altogether directs the anomeric stereo control. A chapter on the glycoside hydrolysis is included in view of the increasing interest in the use of biomass as a natural and renewable source for obtaining important intermediates or products used in food or valuable materials. The author includes information in the characterization of glycosides section with the aim of giving additional tools for the structural assignment through NMR, X-Ray and mass spectra techniques.
Author :
Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)
Download or read book American Doctoral Dissertations written by and published by . This book was released on 2002 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Amelia Pilar Rauter
Publisher : Royal Society of Chemistry
ISBN 13 : 1788010035
Total Pages : 276 pages
Book Rating : 4.7/5 (88 download)
Download or read book Carbohydrate Chemistry written by Amelia Pilar Rauter and published by Royal Society of Chemistry. This book was released on 2017-12-12 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Chemistry demonstrates the interdisciplinary nature of modern carbohydrate research, and benefits any researcher who wishes to learn about the latest developments in the carbohydrate field.
Author : Pher G. Andersson
Publisher : Springer Science & Business Media
ISBN 13 : 364215333X
Total Pages : 244 pages
Book Rating : 4.6/5 (421 download)
Download or read book Iridium Catalysis written by Pher G. Andersson and published by Springer Science & Business Media. This book was released on 2011-01-05 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the contents: Robert H Crabtree: Introduction and History. - Montserrat Diéguez, Oscar Pàmies and Carmen Claver: Iridium-catalysed hydrogenation using phosphorous ligands. - David H. Woodmansee and Andreas Pfaltz: Iridium Catalyzed Asymmetric Hydrogenation of Olefins with Chiral N,P and C,N Ligands. - Ourida Saidi and Jonathan M J Williams: Iridium-catalyzed Hydrogen Transfer Reactions. - John F. Bower and Michael J. Krische: Formation of C-C Bonds via Iridium Catalyzed Hydrogenation and Transfer Hydrogenation. - Jongwook Choi, Alan S. Goldman: Ir-Catalyzed Functionalization of CH Bonds. - Mark P. Pouy and John F. Hartwig: Iridium-Catalyzed Allylic Substitution. - Daniel Carmona and Luis A. Oro: Iridium-catalyzed 1.3-dipolar cycloadditions.
Author :
Publisher : Elsevier
ISBN 13 : 0444632824
Total Pages : 491 pages
Book Rating : 4.4/5 (446 download)
Download or read book Studies in Natural Products Chemistry written by and published by Elsevier. This book was released on 2014-03-05 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry.The series also covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of natural products. - Describes the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents exciting sources of new pharmacophores
Author :
Publisher :
ISBN 13 :
Total Pages : 902 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2007 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Peter H. Seeberger
Publisher : Springer
ISBN 13 : 3319086758
Total Pages : 242 pages
Book Rating : 4.3/5 (19 download)
Download or read book Carbohydrates as Drugs written by Peter H. Seeberger and published by Springer. This book was released on 2014-11-14 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
