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Humoral And Cell Mediated Immune Response Of Channel Catfish Ictalurus Punctatus To Edwardsiella Ictaluri
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Book Synopsis Humoral and Cell-mediated Immune Response of Channel Catfish, Ictalurus Punctatus, to Edwardsiella Ictaluri by : Somsak Vinitnantharat
Download or read book Humoral and Cell-mediated Immune Response of Channel Catfish, Ictalurus Punctatus, to Edwardsiella Ictaluri written by Somsak Vinitnantharat and published by . This book was released on 1991 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Antigen Presenting Cells-Mediated Innate and Adaptive Immune Responses to Live Attenuated Edwardsiella Ictaluri Vaccines in Channel Catfish by :
Download or read book Antigen Presenting Cells-Mediated Innate and Adaptive Immune Responses to Live Attenuated Edwardsiella Ictaluri Vaccines in Channel Catfish written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccination against intracellular pathogens requires generation of pool of memory T cells, which can respond upon infection and mediate immune responses by either killing of infected host cells or induce killing mechanisms in infected cells. T cell-inducing vaccines aim to deliver the antigen to antigen presenting cells (APCs) by presenting on MHC molecules thus bridging innate and adaptive immunity. The intracellular pathogen Edwardsiella ictaluri causes enteric septicemia of catfish (ESC), which is a devastating disease in catfish industry. E. ictaluri can survive in professional phagocytes and use them as an infection source. Two new live attenuated vaccine (LAV) strains, EiDELTAevpB and ESC-NDKL, were developed by our group. However, the role of LAVs in phagocytosis, bacterial killing, and antigen presentation is unexplored. Therefore, further research is necessary to determine immune responses in channel catfish against LAVs. The long-term goal of this project is to identify immunological APC-dependent mechanisms that underscore E. ictaluri pathogenesis to enable development of effective control strategies for ESC. The overall goal of this project is to assess the role of three professional APCs, dendritic cells (DCs), macrophages and B cells in the LAV-induced innate and adaptive immune responses in catfish. The central hypothesis is that efficacious LAV strains will enhance phagocytosis and microbial killing, and promote the generation of T cells that regulate and control protective B cell-mediated immunity. The rationale for this research is that more detailed knowledge about phenotype and function of catfish APCs will not only help gain insight into the evolution of vertebrate adaptive immune system but will provide valuable information for development and optimization of immunotherapies and vaccination protocols for aquaculture use. In this study, we first identified DC-like cells in immune-related organs of catfish an
Book Synopsis Antigen Presenting Cells-mediated Innate and Adaptive Immune Responses to Live Attenuated Edwardsiella Ictaluri Vaccines in Channel Catfish by : Adef Kordon
Download or read book Antigen Presenting Cells-mediated Innate and Adaptive Immune Responses to Live Attenuated Edwardsiella Ictaluri Vaccines in Channel Catfish written by Adef Kordon and published by . This book was released on 2018 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immune Response and Antibody Characterization of the Channel Catfish (Ictalurus Punctatus) to a Naturally Pathogenic Bacterium and Virus by : Charles M. Heartwell
Download or read book Immune Response and Antibody Characterization of the Channel Catfish (Ictalurus Punctatus) to a Naturally Pathogenic Bacterium and Virus written by Charles M. Heartwell and published by . This book was released on 1975 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Partial antibody characterization indicates that specific channel catfish immunoglobulins are macroglobulins with characteristics like those of most fish immunoglobulins and similar to those of human immunoglobulin-M.
Book Synopsis Innate and Adaptive Immune Responses of Channel Catfish to Edwardsiella Ictaluri Wild Type and Live Attenuated Vaccine Candidates by : Ozgur Erdogan
Download or read book Innate and Adaptive Immune Responses of Channel Catfish to Edwardsiella Ictaluri Wild Type and Live Attenuated Vaccine Candidates written by Ozgur Erdogan and published by . This book was released on 2020 with total page 57 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edwardsiella ictaluri causes enteric septicemia of catfish (ESC), a devastating disease in the channel catfish industry. Our research group has developed several E. ictaluri live attenuated vaccine (LAV) candidates (Ei(delta)evpB, Ei(delta)evpB(delta)fur, Ei(delta)evpB(delta)hfq, Ei(delta)evpB(delta)fur(delta)hfq), which were able to stimulate an immune response in vaccinated channel catfish and reduce ESC. However, innate, and adaptive immune responses in the lymphoid tissues of channel catfish to these LAVs are not known well. The overall goal of the project is to determine the role of adaptive and innate immune responses in catfish after vaccination with LAVs. Analysis of innate and adaptive immune-related gene expressions showed that the LAVs induced expression of adaptive immune-related genes in lymphoid tissues with less inflammation compared to wild type control. Also, the LAVs induced the expression of IgM in the sera of catfish.
Book Synopsis Vaccination and Immune Response of Channel Catfish (Ictalurus Punctatus) Against Virulent Aeromonas Hydrophila by : Basant Mahmoud Ali Gomaa
Download or read book Vaccination and Immune Response of Channel Catfish (Ictalurus Punctatus) Against Virulent Aeromonas Hydrophila written by Basant Mahmoud Ali Gomaa and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virulent Aeromonas hydrophila (vAh) is a causative agent of motile Aeromonas septicemia (MAS) in catfish. There are limitations in the current therapeutic and preventative strategies against vAh. The pathogenesis of MAS as well as the immune response of catfish to vAh infection are poorly understood. The aim of this study is to: 1) develop a dual live attenuated vaccine against MAS and enteric septicemia of catfish caused by Edwardsiella ictaluri; and 2) evaluate the vAh bacterial load and gene expression patterns in catfish tissues following vAh infection. Previously, six recombinant vAh proteins (outer membrane protein, TonB-dependent receptor, three fimbrial proteins, and an ATPase) were identified to have vaccine efficacy against MAS, and live attenuated E. ictaluri vaccine strain ESC-NDKL1 was identified as an effective vector for expressing vAh antigens. A total of 29 recombinant ESC-NDKL1 strains have been constructed with the integration of one, two, or three genes encoding vAh antigens into the ESC-NDKL1 chromosome. Vaccine efficacy of the constructed strains was evaluated in channel catfish fingerlings. Four recombinant ESC-NDKL1 strains expressing two vAh antigens (ESC-NDKL1::atpase::fimMrfG, ESC-NDKL1::fim::fimMrfG, ESC-NDKL1::tdr::fimMrfG, and ESC-NDKL1::fim::ompA) showed significant protection against MAS with relative percent of survival (RPS) values of 55.72%, 60.18%, 61.74%, and 54.81%. Four triple recombinant ESC-NDKL1 strains (ESC-NDKL1::fimMrfG::ompA::fimA, ESC-NDKL1::atpase::fimMrfG::ompA, ESC-NDKL1::fim::fimMrfG::ompA and ESC-NDKL1::atpase::tdr::fim) showed the best protection with RPS values of 77.93%, 63.18%, 67.74%, and 82.35%. To gain a better understanding of vAh pathogenesis, catfish fingerlings were intraperitoneally injected with vAh strain ML09-119. The anterior kidney, liver, and spleen were collected for determination of vAh distribution and expression of thirteen pro-inflammatory, innate, and adaptive immune-related genes using real-time PCR. Results revealed that vAh spread into catfish tissues within 2 hours and peaked at 12 hours post-infection. vAh infection initiated a strong inflammatory response in catfish tissues. Additionally, our research revealed that surviving catfish were able to develop a primary immune response and possibly generation of memory B cells against MAS. Such information will facilitate the development of vaccines and therapeutic drugs for preventing and treating MAS outbreaks in catfish aquaculture.
Book Synopsis Immune Response of Channel Catfish to the Edwardsiella Ictaluri Endotoxin by : Jean-Yves Mevel
Download or read book Immune Response of Channel Catfish to the Edwardsiella Ictaluri Endotoxin written by Jean-Yves Mevel and published by . This book was released on 1985 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Ontogeny of the Lymphoid Organs and the Immune Response to Edwardsielle Ictaluri, in Channel Catfish, Ictalurus Punctatus, Fry and Fingerlings by : Lora Jane Petrie-Hanson
Download or read book Ontogeny of the Lymphoid Organs and the Immune Response to Edwardsielle Ictaluri, in Channel Catfish, Ictalurus Punctatus, Fry and Fingerlings written by Lora Jane Petrie-Hanson and published by . This book was released on 1998 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Responses of Channel Catfish, Ictalurus Punctatus, T-lymphocytes to Outer Membrane Proteins of Edwardsiella Ictaluri by : Marlin Ann Lawson
Download or read book Responses of Channel Catfish, Ictalurus Punctatus, T-lymphocytes to Outer Membrane Proteins of Edwardsiella Ictaluri written by Marlin Ann Lawson and published by . This book was released on 1998 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effects of Edwardsiella Ictaluri Infection on Transcriptional Expression of Selected Immune Relevant Genes in Channel Catfish, Ictalurus Punctatus by : Banu Elibol Flemming
Download or read book Effects of Edwardsiella Ictaluri Infection on Transcriptional Expression of Selected Immune Relevant Genes in Channel Catfish, Ictalurus Punctatus written by Banu Elibol Flemming and published by . This book was released on 2006 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Aspects of the Host Response of Channel Catfish, Ictalurus Punctatus, to Edwardsiella Ictaluri by : Paul R. Waterstrat
Download or read book Aspects of the Host Response of Channel Catfish, Ictalurus Punctatus, to Edwardsiella Ictaluri written by Paul R. Waterstrat and published by . This book was released on 1988 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Channel Catfish, Ictalurus Punctatus, T-lymphocyte Mitogenic Responses to Outer Membrane Proteins and LPS of the Gram Negative Rod Bacterium, Edwardsiella Ictaluri by : Barry Revis Hamilton
Download or read book Channel Catfish, Ictalurus Punctatus, T-lymphocyte Mitogenic Responses to Outer Membrane Proteins and LPS of the Gram Negative Rod Bacterium, Edwardsiella Ictaluri written by Barry Revis Hamilton and published by . This book was released on 1995 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Detection of Edwardsiella Ictaluri Antibodies in Channel Catfish, Ictalurus Punctatus, by Rapid Enzyme-linked Immunosorbent Assay Following Infection and Vaccination by : Carolyn J. Ashfield
Download or read book Detection of Edwardsiella Ictaluri Antibodies in Channel Catfish, Ictalurus Punctatus, by Rapid Enzyme-linked Immunosorbent Assay Following Infection and Vaccination written by Carolyn J. Ashfield and published by . This book was released on 1995 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mucosal Health in Aquaculture by : Benjamin H. Beck
Download or read book Mucosal Health in Aquaculture written by Benjamin H. Beck and published by Academic Press. This book was released on 2015-02-17 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mucosal Health in Aquaculture is an essential reference on mucosal health for the diverse aquaculture community. Rich in explanatory figures and schematics, the book includes important concepts such as structural and cellular composition of mucosal surfaces in fish and shellfish, known functional roles of molecular and cellular actors during pathogen invasion, impacts of nutrition on the mucosal barriers, impacts of chemical treatments on mucosal surfaces, mucosal vaccines and vaccination strategies, and more. The health of cultured aquaculture species is critical in establishing the sustainable growth of the aquaculture industry worldwide, and mucosal health is of particular interest to those working in aquaculture because mucosal surfaces (skin, gill, intestine, reproductive tissues) constitute the first line of defense against pathogen invasion. Mucosal Health in Aquaculture captures the latest research on mucosal barriers in aquaculture species and their impacts on nutrition and immunity to ensure sustainable aquaculture development. Includes research case studies to exhibit the importance of various integrated approaches to mucosal health Examines the latest scientific methods and technologies to maximize efficiencies for healthy fish production for farming Brings together the latest knowledge and research on mucosal barriers and mechanisms from world-wide experts in mucosal health Utilizes detailed diagrams and figures to enhance comprehension
Book Synopsis The Immune Response in Channel Catfish (Ictalurus Punctatus) by : Phillip Richard Staley
Download or read book The Immune Response in Channel Catfish (Ictalurus Punctatus) written by Phillip Richard Staley and published by . This book was released on 1972 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Response and Correlated Response to Selection of Channel Catfish, Ictalurus Punctatus, for Resistance to Edwardsiella Ictaluri, Flexibacter Columnaris, Low Levels of Dissolved Oxygen, and Toxic Level of Nitrite by : Phillip Lynch Waters
Download or read book Response and Correlated Response to Selection of Channel Catfish, Ictalurus Punctatus, for Resistance to Edwardsiella Ictaluri, Flexibacter Columnaris, Low Levels of Dissolved Oxygen, and Toxic Level of Nitrite written by Phillip Lynch Waters and published by . This book was released on 2001 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Immune Response of Channel Catfish, Ictalurus Punctatus (Rafinesque), to Ichthyophthirius Multifiliis by : Sopa Areerat
Download or read book The Immune Response of Channel Catfish, Ictalurus Punctatus (Rafinesque), to Ichthyophthirius Multifiliis written by Sopa Areerat and published by . This book was released on 1974 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
