Monitoring Human Tissues for Toxic Substances

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Publisher : National Academies Press
ISBN 13 : 0309044375
Total Pages : 224 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Monitoring Human Tissues for Toxic Substances by : National Research Council

Download or read book Monitoring Human Tissues for Toxic Substances written by National Research Council and published by National Academies Press. This book was released on 1991-02-01 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.

Handbook of Human Tissue Sources. A National Resource of Human Tissue Samples

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Author :
Publisher :
ISBN 13 :
Total Pages : 263 pages
Book Rating : 4.:/5 (227 download)

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Book Synopsis Handbook of Human Tissue Sources. A National Resource of Human Tissue Samples by :

Download or read book Handbook of Human Tissue Sources. A National Resource of Human Tissue Samples written by and published by . This book was released on 1999 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: One aspect of the recent and rapid advances in biological and medical research is that human tissue is being used in an increasing variety of new ways. Now that techniques exist to extract DNA from minuscule archival samples, Including frozen blood or tissue samples and even paraffin-embedded tissue blocks, genetic tests could potentially be performed on virtually any size stored tissue sample. These technological advances, which have been so instrumental in recent biomedical discoveries, have also raised several legal, ethical, and societal issues, including concerns about privacy and informed consent.

Human Tissue Samples: NIH Research Policies and Practices, Serial No. 109-119, 109-2 Hearings, *

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (823 download)

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Book Synopsis Human Tissue Samples: NIH Research Policies and Practices, Serial No. 109-119, 109-2 Hearings, * by : United States. Congress. House. Committee on Energy and Commerce

Download or read book Human Tissue Samples: NIH Research Policies and Practices, Serial No. 109-119, 109-2 Hearings, * written by United States. Congress. House. Committee on Energy and Commerce and published by . This book was released on 2006* with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Case Studies of Existing Human Tissue Repositories

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Author :
Publisher : Rand Corporation
ISBN 13 : 0833035932
Total Pages : 247 pages
Book Rating : 4.8/5 (33 download)

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Book Synopsis Case Studies of Existing Human Tissue Repositories by : Elisa Eiseman

Download or read book Case Studies of Existing Human Tissue Repositories written by Elisa Eiseman and published by Rand Corporation. This book was released on 2003-12-19 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Case studies of twelve existing human biospecimen repositories performed to evaluate their utility for genomics- and proteomics-based cancer research and to identify "best practices" in collection, processing, annotation, storage, privacy, ethical concerns, informed consent, business plans, operations, intellectual property rights, public relations, marketing, and education that would be useful in designing a national biospecimen network.

HUMAN TISSUE SAMPLES: NIH RESEARCH POLICIES AND PRACTICES... HEARINGS... SERIAL NO. 109-119... COMMITTEE ON ENERGY AND COMMERCE, U.S. HOUSE O.

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (664 download)

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Book Synopsis HUMAN TISSUE SAMPLES: NIH RESEARCH POLICIES AND PRACTICES... HEARINGS... SERIAL NO. 109-119... COMMITTEE ON ENERGY AND COMMERCE, U.S. HOUSE O. by : United States. Congress. House. Committee on Energy and Commerce

Download or read book HUMAN TISSUE SAMPLES: NIH RESEARCH POLICIES AND PRACTICES... HEARINGS... SERIAL NO. 109-119... COMMITTEE ON ENERGY AND COMMERCE, U.S. HOUSE O. written by United States. Congress. House. Committee on Energy and Commerce and published by . This book was released on 2007* with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cells and Surveys

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Publisher : National Academies Press
ISBN 13 : 0309171431
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cells and Surveys by : National Research Council

Download or read book Cells and Surveys written by National Research Council and published by National Academies Press. This book was released on 2001-01-19 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: What can social science, and demography in particular, reasonably expect to learn from biological information? There is increasing pressure for multipurpose household surveys to collect biological data along with the more familiar interviewer-respondent information. Given that recent technical developments have made it more feasible to collect biological information in non-clinical settings, those who fund, design, and analyze survey data need to think through the rationale and potential consequences. This is a concern that transcends national boundaries. Cells and Surveys addresses issues such as which biologic/genetic data should be collected in order to be most useful to a range of social scientists and whether amassing biological data has unintended side effects. The book also takes a look at the various ethical and legal concerns that such data collection entails.

Human Tissue Samples

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Publisher : Scholar's Choice
ISBN 13 : 9781296011826
Total Pages : 296 pages
Book Rating : 4.0/5 (118 download)

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Book Synopsis Human Tissue Samples by : United States Congress House of Represen

Download or read book Human Tissue Samples written by United States Congress House of Represen and published by Scholar's Choice. This book was released on 2015-02-14 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Human tissue samples

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Author :
Publisher :
ISBN 13 :
Total Pages : 294 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Human tissue samples by : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations

Download or read book Human tissue samples written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations and published by . This book was released on 2006 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Body Bazaar

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Author :
Publisher : Crown
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Body Bazaar by : Lori B. Andrews

Download or read book Body Bazaar written by Lori B. Andrews and published by Crown. This book was released on 2001 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This disturbing and eye-opening book explores the growing trade in human DNA, blood, tissues, bones, embryos, and other commodities of the burgeoning new biotechnology market.

Stored Tissue Samples

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Publisher : University of Iowa Press
ISBN 13 : 9781587293245
Total Pages : 396 pages
Book Rating : 4.2/5 (932 download)

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Book Synopsis Stored Tissue Samples by : Robert F. Weir

Download or read book Stored Tissue Samples written by Robert F. Weir and published by University of Iowa Press. This book was released on 1998 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Deadly Monopolies

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Publisher : Anchor
ISBN 13 : 0767931238
Total Pages : 450 pages
Book Rating : 4.7/5 (679 download)

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Book Synopsis Deadly Monopolies by : Harriet A. Washington

Download or read book Deadly Monopolies written by Harriet A. Washington and published by Anchor. This book was released on 2012-11-13 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the award-winning author of Medical Apartheid, an exposé of the rush to own and exploit the raw materials of life—including yours. Think your body is your own to control and dispose of as you wish? Think again. The United States Patent Office has granted at least 40,000 patents on genes controlling the most basic processes of human life, and more are pending. If you undergo surgery in many hospitals you must sign away ownership rights to your excised tissues, even if they turn out to have medical and fiscal value. Life itself is rapidly becoming a wholly owned subsidiary of the medical-industrial complex. Deadly Monopolies is a powerful, disturbing, and deeply researched book that illuminates this “life patent” gold rush and its harmful, and even lethal, consequences for public health. Like the bestselling The Immortal Life of Henrietta Lacks, it reveals in shocking detail just how far the profit motive has encroached in colonizing human life and compromising medical ethics.

Conducting Biosocial Surveys

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Publisher : National Academies Press
ISBN 13 : 0309157064
Total Pages : 124 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Conducting Biosocial Surveys by : National Research Council

Download or read book Conducting Biosocial Surveys written by National Research Council and published by National Academies Press. This book was released on 2010-10-02 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen a growing tendency for social scientists to collect biological specimens such as blood, urine, and saliva as part of large-scale household surveys. By combining biological and social data, scientists are opening up new fields of inquiry and are able for the first time to address many new questions and connections. But including biospecimens in social surveys also adds a great deal of complexity and cost to the investigator's task. Along with the usual concerns about informed consent, privacy issues, and the best ways to collect, store, and share data, researchers now face a variety of issues that are much less familiar or that appear in a new light. In particular, collecting and storing human biological materials for use in social science research raises additional legal, ethical, and social issues, as well as practical issues related to the storage, retrieval, and sharing of data. For example, acquiring biological data and linking them to social science databases requires a more complex informed consent process, the development of a biorepository, the establishment of data sharing policies, and the creation of a process for deciding how the data are going to be shared and used for secondary analysis-all of which add cost to a survey and require additional time and attention from the investigators. These issues also are likely to be unfamiliar to social scientists who have not worked with biological specimens in the past. Adding to the attraction of collecting biospecimens but also to the complexity of sharing and protecting the data is the fact that this is an era of incredibly rapid gains in our understanding of complex biological and physiological phenomena. Thus the tradeoffs between the risks and opportunities of expanding access to research data are constantly changing. Conducting Biosocial Surveys offers findings and recommendations concerning the best approaches to the collection, storage, use, and sharing of biospecimens gathered in social science surveys and the digital representations of biological data derived therefrom. It is aimed at researchers interested in carrying out such surveys, their institutions, and their funding agencies.

Dissecting the Molecular Anatomy of Tissue

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783540220060
Total Pages : 252 pages
Book Rating : 4.2/5 (2 download)

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Book Synopsis Dissecting the Molecular Anatomy of Tissue by : Rodrigo F. Chuaqui

Download or read book Dissecting the Molecular Anatomy of Tissue written by Rodrigo F. Chuaqui and published by Springer Science & Business Media. This book was released on 2005-01-12 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.

Sample Preparation in LC-MS Bioanalysis

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Publisher : John Wiley & Sons
ISBN 13 : 111927429X
Total Pages : 384 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Sample Preparation in LC-MS Bioanalysis by : Wenkui Li

Download or read book Sample Preparation in LC-MS Bioanalysis written by Wenkui Li and published by John Wiley & Sons. This book was released on 2019-03-12 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in the footsteps of the previously published Handbook of LC-MS Bioanalysis, this book is a thorough and timely guide to all important sample preparation techniques used for quantitative Liquid Chromatography–Mass Spectrometry (LC-MS) bioanalysis of small and large molecules. LC-MS bioanalysis is a key element of pharmaceutical research and development, post-approval therapeutic drug monitoring, and many other studies used in human healthcare. While advances are continually being made in key aspects of LC-MS bioanalysis such as sensitivity and throughput, the value of research/study mentioned above is still heavily dependent on the availability of high-quality data, for which sample preparation plays the critical role. Thus, this text provides researchers in industry, academia, and regulatory agencies with detailed sample preparation techniques and step-by-step protocols on proper extraction of various analyte(s) of interest from biological samples for LC-MS quantification, in accordance with current health authority regulations and industry best practices. The three sections of the book with a total of 26 chapters cover topics that include: Current basic sample preparation techniques (e.g., protein precipitation, liquid-liquid extraction, solid-phase extraction, salting-out assisted liquid-liquid extraction, ultracentrifugation and ultrafiltration, microsampling, sample extraction via electromembranes) Sample preparation techniques for uncommon biological matrices (e.g., tissues, hair, skin, nails, bones, mononuclear cells, cerebrospinal fluid, aqueous humor) Crucial aspects of LC-MS bioanalytical method development (e.g., pre-analytical considerations, derivation strategies, stability, non-specific binding) in addition to sample preparation techniques for challenging molecules (e.g., lipids, peptides, proteins, oligonucleotides, antibody-drug conjugates) Sample Preparation in LC-MS Bioanalysis will prove a practical and highly valuable addition to the reference shelves of scientists and related professionals in a variety of fields, including pharmaceutical and biomedical research, mass spectrometry, and analytical chemistry, as well as practitioners in clinical pharmacology, toxicology, and therapeutic drug monitoring.

Anatomy & Physiology

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Publisher :
ISBN 13 : 9781955101158
Total Pages : pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Anatomy & Physiology by : Lindsay Biga

Download or read book Anatomy & Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text

Handbook of LC-MS Bioanalysis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111867135X
Total Pages : 709 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Handbook of LC-MS Bioanalysis by : Wenkui Li

Download or read book Handbook of LC-MS Bioanalysis written by Wenkui Li and published by John Wiley & Sons. This book was released on 2013-09-03 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromolecules The field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results. Presenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on routine projects, but also explores advanced and emerging technologies such as high-resolution mass spectrometry and dried blood spot microsampling. Handbook of LC-MS Bioanalysis features contributions from an international team of leading bioanalytical scientists. Their contributions reflect a review of the latest findings, practices, and regulations as well as their own firsthand analytical laboratory experience. The book thoroughly examines: Fundamentals of LC-MS bioanalysis in drug discovery, drug development, and therapeutic drug monitoring The current understanding of regulations governing LC-MS bioanalysis Best practices and detailed technical instructions for LC-MS bioanalysis method development, validation, and stability assessment of analyte(s) of interest Experimental guidelines and protocols for quantitative LC-MS bioanalysis of challenging molecules, including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and photosensitive and autooxidative compounds With its focus on current bioanalytical practice, Handbook of LC-MS Bioanalysis enables bioanalytical scientists to develop and validate robust LC-MS assay methods, all in compliance with current regulations and standards.

The Ethical and Legal Regulation of Human Tissue and Biobank Research in Europe

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Author :
Publisher : Universitätsverlag Göttingen
ISBN 13 : 3863950313
Total Pages : 183 pages
Book Rating : 4.8/5 (639 download)

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Book Synopsis The Ethical and Legal Regulation of Human Tissue and Biobank Research in Europe by : Nils Hoppe

Download or read book The Ethical and Legal Regulation of Human Tissue and Biobank Research in Europe written by Nils Hoppe and published by Universitätsverlag Göttingen. This book was released on 2011 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Human tissue and biobank research is of increasing importance for understanding the causes of widespread diseases and developing effective therapies. However, while the success of biobank research depends on the availability of a large number of samples and the consolidation of collections across country borders is very desirable from the perspective of researchers, the legal and ethical requirements for the procurement, storage and use of human tissue samples are rather heterogeneous across different countries. Moreover, the lack of comprehensive supranational regulation on human tissue and biobanking can be seen as posing a serious threat to transnational biomedical research. Against this background, it was one of the aims of the EU-funded Tiss.EU project ('Evaluation of Legislation and Related Guidelines on the Procurement, Storage and Transfer of Human Tissues and Cells in the European Union--an Evidence-Based Impact Analysis') to analyse the ethical and legal regulation of human tissue and biobank research across the 27 European Member States plus Switzerland. The results of nine international workshops and three conferences are gathered in this volume. While the country reports evaluate the implementation of ethical and legal guidelines at a national level, point out their strengths and deficits, and, where required, create an evidence base for the revision of said legislation, the conference reports address more general ethical and legal issues in this field. The volume is completed by a final presentation of project's results"--Publisher's description