Human Ss Defensins In Airway Epithelial Cells And Leukocytes

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Mechanisms of Epithelial Defense

Author : Dieter Kabelitz
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805578628
Total Pages : 203 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Mechanisms of Epithelial Defense by : Dieter Kabelitz

Download or read book Mechanisms of Epithelial Defense written by Dieter Kabelitz and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Epithelial defense against infectious agents relies on the recognition of microbial products by pattern recognition receptors and the local production of antimicrobial peptides. This book provides a state-of-the-art overview of the basic characteristics and clinical relevance of antimicrobial peptides, with special emphasis on their role in skin, intestinal and lung inflammation. The evolutionary significance of antimicrobial peptides is highlighted by an in-depth analysis of their structure, activity and gene regulation in Drosophila melanogaster. Toll-like receptors are an important class of pattern recognition receptors, whose roles in recognizing bacterial molecular patterns and in the intracellular signalling pathways involved in the differentiation and function of dendritic cells are discussed. Finally, this book also addresses the role of intraepithelial lympho cytes in epithelial defense, notably of T cells which form a link between innate and adaptive immune responses. The combined analysis of epithelial and lymphoid cells and effector mechanisms sheds new light on the epithelial defense system in physiological and pathophysiological conditions. Immunologists, dermatologists, microbiologists, and infectious disease specialists will greatly benefit from the wealth of new findings presented by leading investigators.

Culture of Epithelial Cells

Author : R. Ian Freshney
Publisher : John Wiley & Sons
ISBN 13 : 0471459127
Total Pages : 480 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Culture of Epithelial Cells by : R. Ian Freshney

Download or read book Culture of Epithelial Cells written by R. Ian Freshney and published by John Wiley & Sons. This book was released on 2004-03-24 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: "...a wonderful compendium of current in vitro approaches that will be a useful resource to those just starting to work with an epithelial cell system as well as those that have been working with them for years and years." --Pharmaceutical Research This completely revised and expanded new edition provides detailed descriptions of fundamental and practical aspects relating to the in vitro cultivation of disparate types of epithelia. In recent years, the use of epithelial cell culture in cell biology and tissue engineering has increased dramatically. This revision reflects those advances by including new chapters on the culture of animal and human hepatocytes, kidney epithelium, and bladder epithelium. Each chapter provides an introductory review of the principles and advantages of the particular method, followed by detailed protocols, practical tips, alternate methods, and a useful list of materials and suppliers.

Airway Epithelium

Author : Stephen G. Farmer
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Airway Epithelium by : Stephen G. Farmer

Download or read book Airway Epithelium written by Stephen G. Farmer and published by . This book was released on 1991 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Host Response Mechanisms in Infectious Diseases

Author : Heiko Herwald
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 380557486X
Total Pages : 268 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Host Response Mechanisms in Infectious Diseases by : Heiko Herwald

Download or read book Host Response Mechanisms in Infectious Diseases written by Heiko Herwald and published by Karger Medical and Scientific Publishers. This book was released on 2003 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last decade of intensive research in the field of infectious diseases has resulted in a better conceptual understanding of the molecular mechanisms behind the host-parasite interactions that lead to establishment and progression of the disease. However, with the discovery of an increasing number of species-specific virulence mechanisms and novel host defense strategies, the picture is becoming more and more complex. This volume of the book series Contributions to Microbiology presents a number of selected articles dealing with bacterial and viral pathogens and the resulting host response to infection with these microorganisms. As novel therapeutic anti-bacterial and anti-viral strategies are primarily focused on significant pathophysiological mechanisms, this publication will not only attract the interest of scientific and medical professionals, but will also be of importance for students in the field of microbiology, infectious diseases, cell biology and immunology.

Cummings Otolaryngology - Head and Neck Surgery E-Book

Author : Paul W. Flint
Publisher : Elsevier Health Sciences
ISBN 13 : 0323278205
Total Pages : 4198 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Cummings Otolaryngology - Head and Neck Surgery E-Book by : Paul W. Flint

Download or read book Cummings Otolaryngology - Head and Neck Surgery E-Book written by Paul W. Flint and published by Elsevier Health Sciences. This book was released on 2014-11-28 with total page 4198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its 6th edition, Cummings Otolaryngology remains the world's most detailed and trusted source for superb guidance on all facets of head and neck surgery. Completely updated with the latest minimally invasive procedures, new clinical photographs, and line drawings, this latest edition equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. Be certain with expert, dependable, accurate answers for every stage of your career from the most comprehensive, multi-disciplinary text in the field! Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. Experience clinical scenarios with vivid clarity through a heavily illustrated, full-color format which includes approximately 3,200 images and over 40 high quality procedural videos. Get truly diverse perspectives and worldwide best practices from a multi-disciplinary team of contributors and editors comprised of the world’s leading experts. Glean all essential, up-to-date, need-to-know information. All chapters have been meticulously updated; several extensively revised with new images, references, and content. Stay at the forefront of your field with the most updated information on minimally-invasive surgical approaches to the entire skull base, vestibular implants and vestibular management involving intratympanic and physical therapy-based approaches, radiosurgical treatment of posterior fossa and skull base neoplasms, and intraoperative monitoring of cranial nerve and CNS function. Apply the latest treatment options in pediatric care with new chapters on pediatric sleep disorders, pediatric infectious disease, and evaluation and management of the infant airway. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference. Manage many of the most common disorders with treatment options derived from their genetic basis. Assess real-world effectiveness and costs associated with emergent technologies and surgical approaches introduced to OHNS over the past 10 years. Incorporate recent findings about endoscopic, microscopic, laser, surgically-implantable, radiosurgical, neurophysiological monitoring, MR- and CT-imaging, and other timely topics that now define contemporary operative OHNS. Take it with you anywhere! With Expert Consult, you'll have access the full text, video clips, and more online, and as an eBook - at no additional cost!

Nasal Physiology and Pathophysiology of Nasal Disorders

Author : Özlem Önerci Celebi
Publisher : Springer Nature
ISBN 13 : 3031123867
Total Pages : 588 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Nasal Physiology and Pathophysiology of Nasal Disorders by : Özlem Önerci Celebi

Download or read book Nasal Physiology and Pathophysiology of Nasal Disorders written by Özlem Önerci Celebi and published by Springer Nature. This book was released on 2023-02-20 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised and expanded second edition provides a comprehensive and up-to-date overview of nasal physiology and pathophysiology. With the help of numerous tables, schematic drawings, and color photographs, it helps readers gain a better understanding of the impact of structural changes and the process of disease development, and to make treatment decisions. Each chapter has been written by a leading expert in the field and addresses one important aspect in an accessible way. Covering all four functions of the nose: respiration, defense, olfaction and cosmesis, the book discusses the various techniques for the clinical evaluation of nasal function as well as current trends and future directions in nasal physiologic research. This second edition also includes additional chapters on rhinomanometry, local nasal inflammation, T cells and B cells, and artificial intelligence for the nose. Given its scope, the book is a valuable resource for both experienced otorhinolaryngologists and novices in the field.

Contemporary Oral Microbiology and Immunology

Author : Jørgen Slots
Publisher : Mosby Elsevier Health Science
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Contemporary Oral Microbiology and Immunology by : Jørgen Slots

Download or read book Contemporary Oral Microbiology and Immunology written by Jørgen Slots and published by Mosby Elsevier Health Science. This book was released on 1992 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fetal and Neonatal Physiology E-Book

Author : Richard A. Polin
Publisher : Elsevier Health Sciences
ISBN 13 : 143773636X
Total Pages : 2202 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Fetal and Neonatal Physiology E-Book by : Richard A. Polin

Download or read book Fetal and Neonatal Physiology E-Book written by Richard A. Polin and published by Elsevier Health Sciences. This book was released on 2011-08-13 with total page 2202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease.

Mucosal Immunology

Author : Jiri Mestecky
Publisher : Elsevier
ISBN 13 : 0080454267
Total Pages : 1995 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Mucosal Immunology by : Jiri Mestecky

Download or read book Mucosal Immunology written by Jiri Mestecky and published by Elsevier. This book was released on 2005-02-02 with total page 1995 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mucosal immunology is so important since most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes. Mucosal Immunology, now in its third edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective and excellent organization. - The most comprehensive text on mucosal immunology from internationally recognized experts in the field - Includes exceptional color illustrations, new research data, original theory and information on all mucosal diseases - Contains nine new chapters and an expanded appendix

Fetal and Neonatal Physiology

Author : Richard A. Polin
Publisher : Elsevier Health Sciences
ISBN 13 : 141603479X
Total Pages : 2213 pages
Book Rating : 4.4/5 (16 download)

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Book Synopsis Fetal and Neonatal Physiology by : Richard A. Polin

Download or read book Fetal and Neonatal Physiology written by Richard A. Polin and published by Elsevier Health Sciences. This book was released on 2011-01-01 with total page 2213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease. Access the complete contents and illustrations online at expertconsult.com - fully searchable! Get the latest developments and a full understanding of the distinct physiology of the fetus and newborn so you can treat and manage sick newborns and preemies.

Immunity Against Mucosal Pathogens

Author : Michael Vajdy
Publisher : Springer Science & Business Media
ISBN 13 : 1402084129
Total Pages : 521 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Immunity Against Mucosal Pathogens by : Michael Vajdy

Download or read book Immunity Against Mucosal Pathogens written by Michael Vajdy and published by Springer Science & Business Media. This book was released on 2008-07-09 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surprisingly what separates us from the open environment all around us sometimes is a single layer of epithelial cells. It is at these seemingly fragile sites that most pathogens, including HIV, influenza, emerging and biodefense agents, gain access to our inside milieu. While there are major similarities between the cells and the immune responses generated at the mucosal membranes of the gastrointestinal and respiratory tracts together with the genitourinary tract, there are also important differences. Knowledge of these differences and similarities is required in order to understand the interactions between us, as the host, and the pathogens that attack through each tract, and how our immune system reacts to each of them. Whether we want to devise rational prophylactic or therapeutic vaccines or treatments to either prevent or treat mucosal infections we must acquire such knowledge. This is the rationale behind putting this book together. This book will provide the readers in the areas of vaccinology, virology, bacteriology, epidemiology, immunology and mucosal immunology within academia (undergraduate, graduate, post doctoral fellows and professors), as well as preclinical and clinical scientists in vaccine and drug industries a thorough appreciation of the mucosal immune system and its importance in protecting humans against mucosal pathogens.

Development of the Gastrointestinal Tract

Author : Ian R. Sanderson
Publisher : PMPH-USA
ISBN 13 : 9781550090819
Total Pages : 344 pages
Book Rating : 4.0/5 (98 download)

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Book Synopsis Development of the Gastrointestinal Tract by : Ian R. Sanderson

Download or read book Development of the Gastrointestinal Tract written by Ian R. Sanderson and published by PMPH-USA. This book was released on 2000 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors chronicle the development of the gastrointestinal system b eginning with the embryology of the gastrointestinal tract through dev elopment of cells to hormones and enzymes. Each section provides detai led explanation of that stage of development so residents and clinicia ns can better understand the interrelationships of each structure. Spe cial attention is given to the latest cellular information and gene pr omoters in the regulation of intestinal development. Coverage of defec ts due to trauma and infections is also included.

Coronavirus Replication and Reverse Genetics

Author : Luis Enjuanes
Publisher : Springer Science & Business Media
ISBN 13 : 3540267654
Total Pages : 261 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Coronavirus Replication and Reverse Genetics by : Luis Enjuanes

Download or read book Coronavirus Replication and Reverse Genetics written by Luis Enjuanes and published by Springer Science & Business Media. This book was released on 2005-10-25 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book provides essential information on these viruses and the development of vaccines to control coronavirus infections.

Physiology of the Gastrointestinal Tract, Two Volume Set

Author : Hamid M. Said
Publisher : Academic Press
ISBN 13 : 0123820278
Total Pages : 2250 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Physiology of the Gastrointestinal Tract, Two Volume Set by : Hamid M. Said

Download or read book Physiology of the Gastrointestinal Tract, Two Volume Set written by Hamid M. Said and published by Academic Press. This book was released on 2012-07-04 with total page 2250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis, celiac disease, Crohn's disease, peptic ulcer, stomach ulcer, viral hepatitis, colorectal cancer and liver transplants. The new edition is a highly referenced and useful resource for gastroenterologists, physiologists, internists, professional researchers, and instructors teaching courses for clinical and research students. - 2013 Highly Commended BMA Medical Book Award for Internal Medicine - Discusses the multiple processes governing gastrointestinal function - Each section edited by preeminent scientist in the field - Updated, four-color illustrations

Antibiotics in Laboratory Medicine

Author : Daniel Amsterdam
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1469883635
Total Pages : 1196 pages
Book Rating : 4.4/5 (698 download)

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Book Synopsis Antibiotics in Laboratory Medicine by : Daniel Amsterdam

Download or read book Antibiotics in Laboratory Medicine written by Daniel Amsterdam and published by Lippincott Williams & Wilkins. This book was released on 2014-08-08 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics in Laboratory Medicine has been a mainstay resource for practitioners/providers, investigators, and pharmaceutical researchers of new anti-infective compounds for the past 30 years. This edition includes new chapters on the predictive value of in vitro laboratory testing and the improvement of patient care in the hospital environment through antimicrobial stewardship.

Sensing the Environment: Regulation of Local and Global Homeostasis by the Skin's Neuroendocrine System

Author : Andrzej T. Slominski
Publisher : Springer Science & Business Media
ISBN 13 : 3642196837
Total Pages : 128 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Sensing the Environment: Regulation of Local and Global Homeostasis by the Skin's Neuroendocrine System by : Andrzej T. Slominski

Download or read book Sensing the Environment: Regulation of Local and Global Homeostasis by the Skin's Neuroendocrine System written by Andrzej T. Slominski and published by Springer Science & Business Media. This book was released on 2012-06-02 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The skin, the body’s largest organ, is strategically located at the interface with the external environment where it detects, integrates and responds to a diverse range of stressors, including solar radiation. It has already been established that the skin is an important peripheral neuroendocrine-immune organ that is closely networked with central regulatory systems. These capabilities contribute to the maintenance of peripheral homeostasis. Specifically, epidermal and dermal cells produce and respond to classical stress neurotransmitters, neuropeptides and hormones, production which is stimulated by ultraviolet radiation (UVR), biological factors (infectious and non-infectious) and other physical and chemical agents. Examples of local biologically active products are cytokines, biogenic amines (catecholamines, histamine, serotonin and N-acetyl-serotonin), melatonin, acetylocholine, neuropeptides including pituitary (proopiomelanocortin-derived ACTH, b-endorphin or MSH peptides, thyroid stimulating hormone) and hypothalamic (corticotropin-releasing factor and related urocortins, thyroid-releasing hormone) hormones, as well as enkephalins and dynorphins, thyroid hormones, steroids (glucocorticoids, mineralocorticoids, sex hormones, 7-δ steroids), secosteroids, opioids and endocannabinoids. The production of these molecules is hierarchical, organized along the algorithms of classical neuroendocrine axes such as the hypothalamic pituitary adrenal axis (HPA), hypothalamic-thyroid axis (HPT), serotoninergic, melatoninergic, catecholaminergic, cholinergic, steroid/secosteroidogenic, opioid and endocannabinoid systems. Disruptions of these axes or of communication between them may lead to skin and/or systemic diseases. These local neuroendocrine networks also serve to limit the effect of noxious environmental agents to preserve local and consequently global homeostasis. Moreover, the skin-derived factors/systems can also activate cutaneous nerve endings to alert the brain to changes in the epidermal or dermal environments, or alternatively to activate other coordinating centers by direct (spinal cord) neurotransmission without brain involvement. Furthermore, rapid and reciprocal communications between epidermal and dermal and adnexal compartments are also mediated by neurotransmission including antidromic modes of conduction. Lastly, skin cells and the skin as an organ coordinate and/or regulate not only peripheral but also global homeostasis.

Allergy and Allergic Diseases

Author : A. Barry Kay
Publisher : John Wiley & Sons
ISBN 13 : 144430092X
Total Pages : 2184 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Allergy and Allergic Diseases by : A. Barry Kay

Download or read book Allergy and Allergic Diseases written by A. Barry Kay and published by John Wiley & Sons. This book was released on 2009-01-26 with total page 2184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reserve your copy now This two volume book is an outstanding reference source on allaspects of allergy and allergic diseases. Covering virtually everyallergic condition, from the immunological and molecular basis ofthe allergic response to future trends in allergic diseaseprevention, this new international editorial team (A.B.Kay, JeanBousquet, Pat Holt and Allen Kaplan) have completely revised andupdated the text, from both a scientific and clinical perspective.References will continue to be added to the text until it goes topress making this the most up-to-date book available in thefield. This second edition consists of more than 1,800 pages containedwithin 98 chapters. The price includes a fully searchable companion CD ROM with thecomplete text and over 300 images from the book in full colour.