Human Polyomaviruses

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Polyomaviruses and Human Diseases

Author : Nasimul Ahsan
Publisher : Springer Science & Business Media
ISBN 13 : 0387329579
Total Pages : 383 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Polyomaviruses and Human Diseases by : Nasimul Ahsan

Download or read book Polyomaviruses and Human Diseases written by Nasimul Ahsan and published by Springer Science & Business Media. This book was released on 2007-06-25 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science never solves apr oblem without creating ten more Geor ge Bernard Shaw How prophetic the above words prove to be when applied to the advances of 20th century medicine. Prior to Banting and Best, chnicians were unaware of the ravages of diabetes, patients simply wasted away and died. Following the purifica tion of insulin, clinicians now had to deal with diabetic retinopathy, diabetic neph ropathy and all the other complications of long-term diabetes. A little over 50 years ago, the first successful human kidney transplant was performed in Boston. The first 30 years of the experience had successes when compared to the alternative but were a constant struggle to get even 50% of the grafts from deceased donors to survive more than a year. However, the science continued to advance knowledge of the immune response. With this came more and increasingly powerful tools for the clinician. Suddenly, success rates of 80-90% at one year were attainable. With this success came new problems, new complications and clinicians now had to worry about the long-term consequences of their therapy as patients were surviving with functional grafts for extended periods. A particular infectious complication evolved with the application of ever more powerful immunosuppressant drugs. Astute clinicians noted that occasionally cellular rejections seemed to get worse with steroids. Despite their best efforts and the use of powerful drugs, patients lost their grafts to overwhelming interstitial infiltrates not seen before.

Human Polyomaviruses

Author : Kamel Khalili
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 720 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Human Polyomaviruses by : Kamel Khalili

Download or read book Human Polyomaviruses written by Kamel Khalili and published by Wiley-Liss. This book was released on 2001-10-11 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of human polyomaviruses has evolved profoundly in the last fifteen years, creating an urgent need for an updated resource. Drs. Khalili and Stoner have collected the contributions of renowned researchers and clinicians in this cutting-edge volume.

Molecular Virology of Human Pathogenic Viruses

Author : Wang-Shick Ryu
Publisher : Academic Press
ISBN 13 : 0128009993
Total Pages : 441 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular Virology of Human Pathogenic Viruses by : Wang-Shick Ryu

Download or read book Molecular Virology of Human Pathogenic Viruses written by Wang-Shick Ryu and published by Academic Press. This book was released on 2016-03-30 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author's more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. - Presents viruses within their family structure - Contains recommended journal articles with perspectives to put primary literature in context - Includes integrated recommended reading references within each chapter - Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor's manual, study guide, and test bank

Human Polyomaviruses

Author : Kamel Khalili
Publisher : John Wiley & Sons
ISBN 13 : 0471461024
Total Pages : 714 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Human Polyomaviruses by : Kamel Khalili

Download or read book Human Polyomaviruses written by Kamel Khalili and published by John Wiley & Sons. This book was released on 2004-03-24 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Polyomaviruses Molecular and Clinical perspectives Edited by Kamel Khalili and Gerald L. Stoner Our understanding of human polyomaviruses has evolved profoundly in the last fifteen years, creating an urgent need for an updated resource. Drs. Khalili and Stoner have collected the contributions of renowned researchers and clinicians in this cutting-edge volume. Human Polyomaviruses: Molecular and Clinical Perspectives presents in-depth analyses, comprehensive reviews, and timely assessments of recent discoveries and ongoing controversies focused on these important viral pathogens. Beginning with an historical perspective, this book covers up-to-date investigations into the molecular biology and pathogenesis of human polyomaviruses. All aspects of these persistent infections are subsequently covered, including clinical issues, from diagnosis to information on treatment and drug trials. Central topics are: BK virus JC virus Simian virus 40 (SV40) and its potential as a human pathogen Progressive multifocal leukoencephalopathy (PML) This reference is a superb indoctrination for graduate students, medical students, high-level undergraduates, and anyone engaged in the study of DNA viruses and their molecular biology, evolution, transmission, and pathological potential.

Human Polyomaviruses

Author : Ugo Moens
Publisher : Nova Science Pub Incorporated
ISBN 13 : 9781606928127
Total Pages : 95 pages
Book Rating : 4.9/5 (281 download)

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Book Synopsis Human Polyomaviruses by : Ugo Moens

Download or read book Human Polyomaviruses written by Ugo Moens and published by Nova Science Pub Incorporated. This book was released on 2009 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human polyomaviruses are non-enveloped viruses with a circular double-stranded DNA genome of approximately 5,000 base pairs. The members BK virus and JC virus were first isolated in 1971 and are very common in the human population. Simian virus 40 (SV40), although originally isolated from rhesus macaques and accidentally introduced in the human population during massive poliovirus vaccination, may represent a third member of the polyomaviruses that can have man as a natural host. Primary infection with BK or/and JC virus occurs during early childhood. Subsequently, these viruses establish a seemingly life-long harmless latent infection. However, virus reactivation can occur especially in immunocompromised individuals and JC virus has been recognised as the cause of progressive multifocal leukoencephalopathy, while BK virus-associated interstitial nephritis has become an emerging complication in renal transplant patients. The genomes of human polyomaviruses encode two functional classes of proteins: the regulatory proteins large T-antigen, small t-antigen, and agnoprotein, and the structural proteins VP1, VP2 and VP3 that form the capsid. The regulatory proteins can modulate the expression and/or activity of cellular proteins involved in signal transduction, cell cycle regulation, and chromosomal functions. Therefore, they all possess oncogenic potential. Consistent with this, human polyomaviruses are capable of transforming human cells and inducing tumours in rodents, and are implicated in human malignancies. This book focuses on the etiological role of human polyomaviruses in cancer and highlights the mechanisms by which the viral regulatory proteins may contribute to neoplastic transformation of the infected host cells. Possible therapeutic strategies against these viruses will also be discussed.

Infections Causing Human Cancer

Author : Harald zur Hausen
Publisher : John Wiley & Sons
ISBN 13 : 3527609296
Total Pages : 531 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Infections Causing Human Cancer by : Harald zur Hausen

Download or read book Infections Causing Human Cancer written by Harald zur Hausen and published by John Wiley & Sons. This book was released on 2007-09-24 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen (Nobel Prize in Physiology/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses play a role in the development of this type of cancer.

Principles and Practice of Clinical Virology

Author : Arie J. Zuckerman
Publisher : John Wiley & Sons
ISBN 13 : 0470020962
Total Pages : 912 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Principles and Practice of Clinical Virology by : Arie J. Zuckerman

Download or read book Principles and Practice of Clinical Virology written by Arie J. Zuckerman and published by John Wiley & Sons. This book was released on 2004-08-13 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: The knowledge and practice of clinical virology continues to expand. This new fifth edition has thirty-six comprehensive chapters, each of which has been extensively revised or rewritten, with the addition of new colour plates. This updated version takes into account knowledge accumulated in molecular biology with its applications for laboratory diagnosis, immunisation and antiviral chemotherapy. Each chapter highlights the clinical features and epidemiological patterns of infection. Similarly, in response to the global concern of the threat posed by new viruses, a new chapter on Emerging Infections is included. There is also new material on Hospital Acquired Infections, including some advice relating to SARS, that will be of benefit to those dealing with the day-to-day management of patients in hospital.

Fenner and White's Medical Virology

Author : Christopher J. Burrell
Publisher : Academic Press
ISBN 13 : 0123751578
Total Pages : 605 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Fenner and White's Medical Virology by : Christopher J. Burrell

Download or read book Fenner and White's Medical Virology written by Christopher J. Burrell and published by Academic Press. This book was released on 2016-11-09 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. - Features updated and expanded coverage of pathogenesis and immunity - Contains the latest laboratory diagnostic methods - Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control

Diagnostic Microbiology of the Immunocompromised Host

Author : Randall T. Hayden
Publisher : John Wiley & Sons
ISBN 13 : 1683673190
Total Pages : 1576 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Diagnostic Microbiology of the Immunocompromised Host by : Randall T. Hayden

Download or read book Diagnostic Microbiology of the Immunocompromised Host written by Randall T. Hayden and published by John Wiley & Sons. This book was released on 2016-08-01 with total page 1576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategies for providing optimal care to this high-risk patient group The immunocompromised patient population is increasing throughout the world. Major advances in transplantation techniques have expanded access to lifesaving therapies and improved outcomes in these high-risk populations. An understanding of the biology of these infections, host conditions, and the limitations of technologies used to detect and quantify such pathogens is critical to optimal care. This new edition of Diagnostic Microbiology of the Immunocompromised Host covers all aspects of state-of-the-art diagnostics for infectious complications in the immunocompromised patient. Editors Randall Hayden, Karen Carroll, Yi-Wei Tang and Donna Wolk, assembled the contributions of a team of preeminent authors to discuss a broad range of topics, including relevant aspects of host biology, antineoplastic, and transplantation techniques and the basis of immunosuppressive conditions ranging from diabetes to age-related immunosuppression approaches, interpretations, and limitations of laboratory diagnosis of infections by a wide range of specific etiologic agents laboratory diagnosis of infections of specific organ systems, such as respiratory tract infections, gastrointestinal tract infections, and central nervous system infections special topics such as prosthetic devices and catheters, healthcare acquired infections, and morphologic considerations (anatomic pathology) future diagnostic technologies and their potential impact on the field Diagnostic Microbiology of the Immunocompromised Host is a resource for laboratory medicine specialists, pathologists, technologists, students, and clinical care professionals who are involved or interested in the care of the immunocompromised host. If you are looking for online access to the latest clinical microbiology content, please visit www.wiley.com/learn/clinmicronow.

Infections of the Central Nervous System

Author : Fabrice Chretien
Publisher : John Wiley & Sons
ISBN 13 : 1119467799
Total Pages : 894 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Infections of the Central Nervous System by : Fabrice Chretien

Download or read book Infections of the Central Nervous System written by Fabrice Chretien and published by John Wiley & Sons. This book was released on 2020-01-08 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: Der neue Band aus der Reihe International Society of Neuropathology wurde anlässlich der British Medical Association (BMA) Awards 2019 wärmstens empfohlen. Die Herausgeber sind Experten des Fachgebiets und beschreiben Infektionen des Nervensystems mit ihren klinischen, pathologischen und genetischen Eigenheiten. Auch seltene Erkrankungen werden in übersichtlichen Kapiteln erläutert, zusammen mit Definitionen, mikrobiologischen Eigenschaften, Epidemiologie, klinischen Ausprägungen, Labortests, Pathologie, Genetik und Behandlungsoptionen.

A Practical Guide to Clinical Virology

Author : L. R. Haaheim
Publisher : John Wiley & Sons
ISBN 13 : 0470856874
Total Pages : 306 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis A Practical Guide to Clinical Virology by : L. R. Haaheim

Download or read book A Practical Guide to Clinical Virology written by L. R. Haaheim and published by John Wiley & Sons. This book was released on 2003-04-04 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Second Edition of A Practical Guide to Clinical Virology is a practical, highly illustrated, quick reference guide to clinical virology. It brings together the essentials of the subject in a entertaining and informative style, describing in turn the clinical features, the symptoms and signs of each of the viral diseases, as well as summarising the epidemiology, laboratory diagnosis and therapy in each case. This book also includes general chapters on classification, diagnosis of infection, antiviral drugs, vaccines and different clinical syndromes. Key Features: Chapter summaries for quick reference Cartoon illustrations Comprehensive coverage Clear and concise format Each chapter is easy to read and well organised, ensuring that this is an invaluable textbook for all medical, biomedical, microbiology and applied biology students. In addition, it provides an excellent reference for nurses, occupational health and infection control departments, public health and diagnostic laboratories.

Clinical Infectious Diseases Study Guide

Author : Joseph Domachowske
Publisher : Springer Nature
ISBN 13 : 3030508730
Total Pages : 357 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Clinical Infectious Diseases Study Guide by : Joseph Domachowske

Download or read book Clinical Infectious Diseases Study Guide written by Joseph Domachowske and published by Springer Nature. This book was released on 2020-08-05 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is meticulously designed for the busy student, trainee, or seasoned physician looking to enhance or refresh skills in infectious diseases. It is intended to provide a solid resource for students and physicians in need of a concise yet comprehensive background of the material. Each chapter begins with a summary of the topic, a brief case description, definitions, critical teaching points, and tables, figures, photos, and other visual materials to reinforce learning. The chapters take a systems based approach to infections before concluding with the essentials of diagnostic microbiology to leave users with a practical toolkit for real-world clinics. Authored by two expert educators and dual infectious diseases and pediatrics specialists, Clinical Infectious Diseases Study Guide is the only updated study guide designed for medical students, fellows, residents, and trainees who need a strong foundation in infectious diseases. This includes infectious disease specialists in both adult and pediatric care, various internal medicine subspecialists, and hospitalists.

Clinical Virology

Author : Douglas D. Richman
Publisher : John Wiley & Sons
ISBN 13 : 1555819435
Total Pages : 1489 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Clinical Virology by : Douglas D. Richman

Download or read book Clinical Virology written by Douglas D. Richman and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 1489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential reference of clinical virology Virology is one of the most dynamic and rapidly changing fields of clinical medicine. For example, sequencing techniques from human specimens have identified numerous new members of several virus families, including new polyomaviruses, orthomyxoviruses, and bunyaviruses. Clinical Virology, Fourth Edition, has been extensively revised and updated to incorporate the latest developments and relevant research. Chapters written by internationally recognized experts cover novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, organized into two major sections: Section 1 provides information regarding broad topics in virology, including immune responses, vaccinology, laboratory diagnosis, principles of antiviral therapy, and detailed considerations of important organ system manifestations and syndromes caused by viral infections. Section 2 provides overviews of specific etiologic agents and discusses their biology, epidemiology, pathogenesis of disease causation, clinical manifestations, laboratory diagnosis, and management. Clinical Virology provides the critical information scientists and health care professionals require about all aspects of this rapidly evolving field.

Transplant Infections

Author : Per Ljungman
Publisher : Springer
ISBN 13 : 3319287974
Total Pages : 983 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Transplant Infections by : Per Ljungman

Download or read book Transplant Infections written by Per Ljungman and published by Springer. This book was released on 2016-10-03 with total page 983 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients undergoing hematotopoietic or solid organ transplantation increases, a deep understanding of the field of transplant infectious diseases grows increasingly vital. With its extensively revised and updated review of surgical infections, treatment, prevention, and practice, this book is the ultimate guide to advances in the field of transplant infections that are rapidly implemented into practice both in diagnostic technologies, new therapies, new transplant practices, and challenges such as the threat of multiresistant bacteria and the increasing use of transplantation in the developing parts of the world. Written by experts in their fields, this book is the only comprehensive source of cutting-edge information on transplant infections and has been a trusted guide to medical professionals worldwide for nearly two decades. Transplant Infections is of paramount value to infectious disease specialists, transplant physicians, medical students, fellows, residents, and all medical professionals working with surgical patients.

Immunization Safety Review

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309086108
Total Pages : 118 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Immunization Safety Review by : Institute of Medicine

Download or read book Immunization Safety Review written by Institute of Medicine and published by National Academies Press. This book was released on 2003-12-26 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.

DNA Tumor Viruses

Author : Blossom Damania
Publisher : Springer Science & Business Media
ISBN 13 : 0387689451
Total Pages : 805 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis DNA Tumor Viruses by : Blossom Damania

Download or read book DNA Tumor Viruses written by Blossom Damania and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.

Human Papillomavirus

Author : M.K. Ramírez-Fort
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318025275
Total Pages : 282 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Human Papillomavirus by : M.K. Ramírez-Fort

Download or read book Human Papillomavirus written by M.K. Ramírez-Fort and published by Karger Medical and Scientific Publishers. This book was released on 2014-03-13 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human papillomavirus (HPV) infection transcends multiple fields of science and medicine. The management of HPV-related disease is demanding and often requires a persistent multimodal approach involving various medical disciplines. In this volume, experts present a comprehensive view of HPV research with an emphasis on clinical presentations, diagnosis, management and vaccine development. The state of the art in molecular biology is provided in addition to discussions on clinical morphology and the utility of dermatoscopy in identifying HPV disease. In a multidisciplinary approach to dermatological, plastic and reconstructive, gynecological, otolaryngological and colorectal management, different treatment strategies are highlighted. Finally, Dr. Neil Christensen discusses viral immunology, and the difficulties and successes in the development of an HPV vaccine. Bringing together basic science and clinical information on HPV, this book is an excellent resource and reference for all researchers and clinicians who encounter human papillomavirus-related disease.