Human Experimentation and Research

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Publisher : Routledge
ISBN 13 : 1351772384
Total Pages : 1160 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis Human Experimentation and Research by : George F. Tomossy

Download or read book Human Experimentation and Research written by George F. Tomossy and published by Routledge. This book was released on 2017-07-12 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title was first published in 2003: As new medical technologies and treatments develop with increasing momentum, the legal and ethical implications of research involving human participants are being called into question as never before. Human Experimentation and Research explores the philosophical foundations of research ethics, ongoing regulatory dilemmas, and future challenges raised by the rapid globalisation and corporatisation of the research endeavour. This volume brings together some of the most significant published essays in the field. The editors also provide an informative introduction, summarizing the area and the relevance of the articles chosen.

The Arctic Aeromedical Laboratory's Thyroid Function Study

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Publisher : National Academies Press
ISBN 13 : 0309588847
Total Pages : 98 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis The Arctic Aeromedical Laboratory's Thyroid Function Study by : Committee on Evaluation of 1950s Air Force Human Health Testing in Alaska Using Radioactive Iodine-131

Download or read book The Arctic Aeromedical Laboratory's Thyroid Function Study written by Committee on Evaluation of 1950s Air Force Human Health Testing in Alaska Using Radioactive Iodine-131 and published by National Academies Press. This book was released on 1996-02-09 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the 1950s, with the Cold War looming, military planners sought to know more about how to keep fighting forces fit and capable in the harsh Alaskan environment. In 1956 and 1957, the U.S. Air Force's former Arctic Aeromedical Laboratory conducted a study of the role of the thyroid in human acclimatization to cold. To measure thyroid function under various conditions, the researchers administered a radioactive medical trace, Iodine-131, to Alaska Natives and white military personnel; based on the study results, the researchers determined that the thyroid did not play a significant role in human acclimatization to cold. When this study of thyroid function was revisited at a 1993 conference on the Cold War legacy in the Arctic, serious questions were raised about the appropriateness of the activity--whether it posed risks to the people involved and whether the research had been conducted within the bounds of accepted guidelines for research using human participants. In particular, there was concern over the relatively large proportion of Alaska Natives used as subjects and whether they understood the nature of the study. This book evaluates the research in detail, looking at both the possible health effects of Iodine-131 administration in humans and the ethics of human subjects research. This book presents conclusions and recommendations and is a significant addition to the nation's current reevaluation of human radiation experiments conducted during the Cold War.

The Patient as Partner

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Publisher :
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Patient as Partner by : Robert M. Veatch

Download or read book The Patient as Partner written by Robert M. Veatch and published by . This book was released on 1987 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the essays included are edited and revised versions of essays originally written from 1971-1983.

The Ethics and Politics of Human Experimentation

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Publisher : CUP Archive
ISBN 13 : 9780521416276
Total Pages : 340 pages
Book Rating : 4.4/5 (162 download)

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Book Synopsis The Ethics and Politics of Human Experimentation by : Paul Murray McNeill

Download or read book The Ethics and Politics of Human Experimentation written by Paul Murray McNeill and published by CUP Archive. This book was released on 1993-05-28 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author finds that these committees are predominantly influenced by members of research institutions and by the researchers themselves. Yet researchers, and their institutions, stand to gain considerable benefits from the experiments they conduct. Dr McNeill argues that committees of review, as they are presently constituted, cannot be relied on to ensure an equitable balance between the interests of researchers and the interests of the human subjects experimented on. He proposes a radically different rationale and model for committee review.

Human Experimentation and Medical Ethics

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Publisher :
ISBN 13 :
Total Pages : 524 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Human Experimentation and Medical Ethics by : Zbigniew Bańkowski

Download or read book Human Experimentation and Medical Ethics written by Zbigniew Bańkowski and published by . This book was released on 1982 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: references throughout

The Use of Human Beings in Research

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Publisher : Springer Science & Business Media
ISBN 13 : 9400927053
Total Pages : 301 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis The Use of Human Beings in Research by : S.F. Spicker

Download or read book The Use of Human Beings in Research written by S.F. Spicker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, which has developed from the Fourteenth Trans Disciplinary Symposium on Philosophy and Medicine, September 5-8, 1982, at Tel Aviv University, Israel, contains the contributions of a group of distinguished scholars who together examine the ethical issues raised by the advance of biomedical science and technology. We are, of course, still at the beginning of a revolution in our understanding of human biology; scientific medicine and clinical research are scarcely one hundred years old. Both the sciences and the technology of medicine until ten or fifteen years ago had the feeling of the 19th century about them; we sense that they belonged to an older time; that era is ending. The next twenty-five to fifty years of investigative work belong to neurobiology, genetics, and reproductive biology. The technologies of information processing and imaging will make diagnosis and treatment almost incomprehensible by my generation of physicians. Our science and technology will become so powerful that we shall require all of the art and wisdom we can muster to be sure that they remain dedicated, as Francis Bacon hoped four centuries ago, "to the uses of life." It is well that, as philosophers and physicians, we grapple with the issues now when they are relatively simple, and while the pace of change is relatively slow. We require a strategy for the future; that strategy must be worked out by scientists, philosophers, physicians, lawyers, theologians, and, I should like to add, artists and poets.

Ethical Research

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Publisher : Oxford University Press, USA
ISBN 13 : 0190224177
Total Pages : 611 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Ethical Research by : Ulf Schmidt

Download or read book Ethical Research written by Ulf Schmidt and published by Oxford University Press, USA. This book was released on 2020 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the heart of research with human beings is the moral notion that the experimental subject is altruistic, and is primarily concerned for the welfare of others. Beneath the surface, however, lies a very different ethical picture. Individuals participating in potentially life-saving research sometimes take on considerable risks to their own well-being. Efforts to safeguard human participants in clinical trials have intensified ever since the first version of the World Medical Association's Declaration of Helsinki (1964) and are now codified in many national and international laws and regulations. However, a comprehensive understanding of how this cornerstone document originated, changed, and functions today does not yet exist in the sphere of human research. Ethical Research brings together the work of leading experts from the fields of bioethics, health and medical law, the medical humanities, biomedicine, the medical sciences, philosophy, and history. Together, they focus on the centrality of the Declaration of Helsinki to the protection of human subjects involved in experimentation in an increasingly complex industry and in the government-funded global research environment. The volume's historical and contemporary perspectives on human research address a series of fundamental questions: Is our current human protection regime adequately equipped to deal with new ethical challenges resulting from advances in high-tech biomedical science? How important has the Declaration been in non-Western regions, for example in Eastern Europe, Africa, China, and South America? Why has the bureaucratization of regulation led to calls to pay greater attention to professional responsibility? Ethical Research offers insight into the way in which philosophy, politics, economics, law, science, culture, and society have shaped, and continue to shape, the ideas and practices of human research.

History and Theory of Human Experimentation

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Author :
Publisher : Franz Steiner Verlag Wiesbaden GmbH
ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis History and Theory of Human Experimentation by : Ulf Schmidt

Download or read book History and Theory of Human Experimentation written by Ulf Schmidt and published by Franz Steiner Verlag Wiesbaden GmbH. This book was released on 2007 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite having been revised and criticised over the years, the Declaration of Helsinki remains one of the most important and internationally known ethics codes worldwide. Yet we know relatively little about its historical origins or about the prolonged revision process which accompanied this "living document". The chapters presented in this volume look at the history and theory of human experimentation, assess the role of the Helsinki Declaration in an international context, and illustrate specific issues about the history and practice of research ethics through a number of case studies in the United States, Asia and Europe. To this day, the Declaration is one of the most important landmarks in human subject research which is aimed at protecting experimental subjects in society. The current volume offers a better and historically-informed understanding of the Declaration to ensure that the existing safeguards are not only preserved but developed and improved in the future. Die 1964 veroffentlichte Deklaration zu Helsinki ist einer der wichtigsten und international bekanntesten Kodizes zur Forschungsethik, dessen Entstehungsgeschichte von steter Kritik und zahlreichen Uberarbeitungen begleitet wurde. Dennoch weiss man relativ wenig uber die historischen Wurzeln und Novellierungsprozesse dieses "gewachsenen Dokuments" der Medizingeschichte. Bis zum heutigen Tag ist die Deklaration einer der bedeutendsten Wegweiser fur die Forschung am Menschen, deren grundsatzliches Ziel es ist, Versuchspersonen in medizinischen Experimenten zu schutzen. Der Band beleuchtet Geschichte und Theorie der Experimente am Menschen, untersucht die Rolle der Deklaration im internationalen Kontext und illustriert spezifische Themen zur Geschichte und Praxis der Forschungsethik anhand von Fallstudien zu den USA, Asien und Europa. Ausserdem geben die Studien Einblick in die Entstehungsgeschichte der Deklaration - nicht nur um die bestehenden Standards zum Schutz von Versuchspersonen zu bewahren, sondern auch um diese zukunftig weiterzuentwickeln und zu verbessern. Aus dem Inhalt Ulf Schmidt / Andreas Frewer: History and Ehtics of Human Experimentation: the Twisted Road to Helsinki. An Introduction History and Theory of Medical Research Ethics Ulrich Trohler: The Long Road of Moral Concern: Doctors' Ethos and Statute Law Relating to Human Research in Europe Dietrich von Engelhardt: The Historical and Philosophical Background of Ethics in Clinical Research Ulf Schmidt: The Nuremberg Doctors' Trial and the Nuremberg Code Till Barnighausen: Communicating "Tainted Science" The Japanese Biological Warfare Experiments on Human Subjects in China The Helsinki Declaration in an International Context Susan E. Lederer: Research Without Borders: The Origins of the Declaration of Helsinki Povl Riis: Forty Years of the Declaration of Helsinki: Progress in Medical Ethics? Kati Myllymaki: Revising the Declaration of Helsinki: An Insiders' View Robert Carlson / Kenneth Boyd / David Webb: The Interpretation of Codes of Medical Ethics: Some Lessons from the Fifth Revision of the Declaration of Helsinki David Willcox: Medical Ethics and Public Perception: The Declaration of Helsinki and its Revisions in 2000 Dominique Sprumont / Sara Girardin / Trudo Lemmens: The Helsinki Declaration and the Law: An International and Comparative Analysis History and Ethics of Research - International Perspectives Andreas Frewer: History of Medicine and Ethics in Conflict: Research on National Socialism as Moral Problem Ulf Schmidt: Medical Ethics and Human Experiments at Porton Down: Informed Consent in Britain's Biological and Chemical Warfare Experiments John Williams: The Declaration of Helsinki. The Importance of Context Jonathan D. Moreno: Helsinki into the Future. An Epilogue Key Documents on the History of Research Ethics Circular of the Reich Minister of the Interior Concerning Guidelines for New Therapy and Human Experimentation (Berlin, 1931) - The Nuremberg Code (1947) - World Medical Association: Declaration of Helsinki I (1964) - World Medical Association: Declaration of Helsinki II (Tokyo, 1975) - Council of Europe: Convention on Human Rights and Biomedicine (Oviedo, 1997) - World Medical Association: Declaration of Helsinki (2004)

Ethics and Regulation of Clinical Research

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Publisher : Yale University Press
ISBN 13 : 9780300042887
Total Pages : 484 pages
Book Rating : 4.0/5 (428 download)

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Book Synopsis Ethics and Regulation of Clinical Research by : Robert J. Levine

Download or read book Ethics and Regulation of Clinical Research written by Robert J. Levine and published by Yale University Press. This book was released on 1988-01-01 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of human subjects in medical and scientific research has given rise to troubling ethical questions. How should human subjects be selected for experiments? What should they be told about the research in which they are involved? How can their privacy be protected? When is it permissible to deceive them? How do we deal with subjects such as children, fetuses, and the mentally infirm, for whom informed consent is impossible? In this book, Dr. Robert J. Levine reviews federal regulations, ethical analysis, and case studies in an attempt to answer these questions. His book is an essential reference for everyone--members of institutional review boards, scientists, philosophers, lawyers--addressing the ethical issues involved. "[Levine's] experience as a clinician, IRB chairman, writer and editor of a journal devoted exclusively to issues faced by IRBS makes him uniquely qualified to bring together the legal, ethical, and practical dimensions. . . [The book] is sophisticated but readable. . . [and] should be on every IRB administrator's desk and in every medical ethics library."--Norman Fost, M.D., The New England Journal of Medicine "Levine. . . is one of the foremost historians of contemporary clinical science. . . . His book is at once a guide to primary sources for the history of clinical research in the late twentieth century and a pioneering secondary source about that history."--Daniel M. Fox, Bulletin of the History of Medicine "You will be charmed by the [book's] elegance and lucidity and. . . persuaded of its relevance to doctors in any country."--Alex Paton, British Medical Journal "Should be of wide interest to those keen to see advances in medical research brought into general medical practice."--Gilbert Omenn, Issues in Science and Technology

Research on Human Subjects

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Author :
Publisher : Russell Sage Foundation
ISBN 13 : 1610440250
Total Pages : 270 pages
Book Rating : 4.6/5 (14 download)

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Book Synopsis Research on Human Subjects by : Bernard Barber

Download or read book Research on Human Subjects written by Bernard Barber and published by Russell Sage Foundation. This book was released on 1973-03-01 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: How are human subjects treated in biomedical research? What are the expressed standards and self-reported behavior of biomedical researchers in regard to what has sometimes been called their "animal of necessity"? What are some of the determinants of the "strict" and "permissive" patterns which describe the standards and behavior of biomedical researchers? These are the important questions asked and answered in Research on Human Subjects. It is a book based on four years of intensive research. Two studies were completed, one on a nationally representative sample of biomedical research institutions, a second on a sample of 350 researchers who actually use human subjects. In their chapters on "the dilemma of science and therapy," the authors look at the tension between the values of humane therapy and discovery in science. They show that the significant minority of researchers who are "permissive" on the issues of informed consent and a favorable risk-benefit ratio are more likely to be those who are "relative failures" in pursuing the science value. Research on Human Subjects also documents the inadequate training that biomedical researchers get in the ethics of research on human subjects not only in medical schools but in their postgraduate training as well. The medical schools pay relatively more attention to the scientific training of their students than they do to the ethical training that should be its essential complement. The local peer review groups that screen research on human subjects in the institutions where it is carried on are another central focus of attention of the research and analysis reported in this book. The peer review groups do a fairly good job but, the authors show, there are various conditions of their relative efficacy which are not met by review groups in many important research institutions. The medical school review groups, for example, have not been outstanding performers with respect to the several conditions of relative efficacy. In the concluding chapter, the authors discuss the general problem of the social responsibilities of powerful professions and make very specific suggestions for policy change and reform for the biomedical research profession and its use of human subjects.

Dark Medicine

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Publisher : Indiana University Press
ISBN 13 : 0253220416
Total Pages : 282 pages
Book Rating : 4.2/5 (532 download)

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Book Synopsis Dark Medicine by : William R. LaFleur

Download or read book Dark Medicine written by William R. LaFleur and published by Indiana University Press. This book was released on 2008-07-17 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of essays looks at the dark medical research conducted during and after World War II. Contributors describe this research, how it was brought to light, and the rationalisations of those who perpetrated and benefited from it.

Twentieth century ethics of human subjects research

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Publisher : Franz Steiner Verlag
ISBN 13 : 9783515084550
Total Pages : 370 pages
Book Rating : 4.0/5 (845 download)

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Book Synopsis Twentieth century ethics of human subjects research by : Volker Roelcke

Download or read book Twentieth century ethics of human subjects research written by Volker Roelcke and published by Franz Steiner Verlag. This book was released on 2004 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Debates on the ethics of human subjects research meet with an increasing interest both within the medical profession and the broader public. Frequently, historical arguments are used to propagate or attack certain positions within these debates. However, there is a tendency to oversimplify the complexities of the past for present day purposes, and at the same time a lack of awareness of the historical dimension implicit in today's value preferences. Twentieth Century Ethics of Human Subjects Research brings together leading historians of medicine to reconstruct and analyse the history of actual experimental practices, the debates on human subjects research, and the attempts to regulate such research during the twentieth century. The volume addresses cases of medical research in France, Britain, Israel, the United States, and Germany, including the Nazi period; the major developments of ethical debates in these and further national contexts, such as the Soviet Union, the Czech Republic, and Japan. It also explores religious views (Catholic, Jewish) on human experimentation, and the origins and contexts of international codes and declarations. "Volker Roelckes Uberblick uber die Geschichte der Menschenversuche im Dritten Reich sei jedem empfohlen, der sich kurz und pragnant uber dieses dustere Kapitel deutscher Geschichte informieren mochte." FAZ.

Experimentation with Human Subjects

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Author :
Publisher : George Braziller
ISBN 13 : 9780807605424
Total Pages : 492 pages
Book Rating : 4.6/5 (54 download)

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Book Synopsis Experimentation with Human Subjects by : Paul Abraham Freund

Download or read book Experimentation with Human Subjects written by Paul Abraham Freund and published by George Braziller. This book was released on 1970 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the essays appeared in the spring 1969 issue of Dædalus.

The Ethics of Animal and Human Experimentation

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Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 396 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Ethics of Animal and Human Experimentation by : Peter P. Deyn

Download or read book The Ethics of Animal and Human Experimentation written by Peter P. Deyn and published by Butterworth-Heinemann. This book was released on 1994 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume on ethical considerations regarding biomedical experimental methods and techniques focuses on ethical problems present in animal and human experimentation. It presents a multi-disciplinary approach, with chapters written by philosophers, statisticians, lawyers, clinical and laboratory researchers. Contributors represent academia and industry, as well as animal rights organizations.

Military Medical Ethics, Volume 1

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Publisher : DIANE Publishing
ISBN 13 : 1428910654
Total Pages : 436 pages
Book Rating : 4.4/5 (289 download)

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Book Synopsis Military Medical Ethics, Volume 1 by :

Download or read book Military Medical Ethics, Volume 1 written by and published by DIANE Publishing. This book was released on with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research on Human Subjects

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Publisher : Pergamon
ISBN 13 :
Total Pages : 692 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research on Human Subjects by : D.N. Weisstub

Download or read book Research on Human Subjects written by D.N. Weisstub and published by Pergamon. This book was released on 1998-10-23 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been serious controversies in the latter part of the 20th century about the roles and functions of scientific and medical research. In whose interests are medical and biomedical experiments conducted and what are the ethical implications of experimentation on subjects unable to give competent consent? From the decades following the Second World War and calls for the global banning of medical research to the cautious return to the notion that in controlled circumstances, medical research on human subjects is in the best interest of the given individual and the broader population, this book addresses the key implications of experimentation on humans. This volume covers major ethical themes within biomedical research providing historical, philosophical, legal and policy reflections on the literature and specific issues in the field of research on human subjects. Focusing on special populations (the elderly, children, prisoners and the cognitively impaired) it represents the most up-to-date review of the special ethical and legal conflicts that arise with relation to experimentation on subjects from these groups. In the light of current initiatives for law reform pertaining to research ethics the world over, this volume provides a timely, comprehensive and provocative exploration of the field. The volume has been carefully organized to present important philosophical perspectives on organizing principles that should underlie any practical application. A forward-looking historical review of the regulatory regimes of principal jurisdictions, including of the legal controls already in place, provides the backdrop for future policy initiatives. Additionally, in the light of global restructuring of health care systems, several chapters have been devoted to epidemiological research and related issues.

Subjected to Science

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Publisher : JHU Press
ISBN 13 : 9780801857096
Total Pages : 226 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Subjected to Science by : Susan E. Lederer

Download or read book Subjected to Science written by Susan E. Lederer and published by JHU Press. This book was released on 1997-11-07 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Susan Lederer provides the first full-length history of early biomedical research with human subjects. Lederer offers detailed accounts of experiments conducted on both healthy and unhealthy men, women, and children, during the period from 1890 to 1940, including yellow fever experiments, Udo Wile's "dental drill" experiments on insane patients, and Hideyo Noguchi's syphilis experiments.