Author : Denise E. Rooney
Publisher : Oxford University Press, USA
ISBN 13 : 9780199638413
Total Pages : 330 pages
Book Rating : 4.6/5 (384 download)
Book Synopsis Human Cytogenetics by : Denise E. Rooney
Download or read book Human Cytogenetics written by Denise E. Rooney and published by Oxford University Press, USA. This book was released on 2001 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advent of molecular technologies has lead to a rapid acceleration in the cytogenetic study of malignancy and acquired abnormalities. As well as having a chapter devoted to molecular technologies (FISH, PRINS, and CGH), molecular methodology is emphasized in all chapters, for example the role of CGH in solid tumour cytogenetics. Classical techniques are not forgotten, with a detailed description of the preparation and analysis of chromosomes from bone marrow and leukaemic blood. This is followed by three chapters on the specific methodology for the cytogenetic study of myeloid leukaemia, acute lymphoblastic leukaemia, and lymphomas and lymphoproliferative disorders. Also covered are chromosome instability syndromes, mutagen-induced chromosome damage in lymphocytes and the role of cytogenetics in the assessment of haematological disorders. This book will be invaluable to any scientists using cytogenetics to study malignancy and along with its sister volume Human Cytogenetics: Constitutional Analysis will be an essential purchase for any cytogenetics laboratory. The volumes are available individually or as a set.