Human Carcinogen Exposure

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Carcinogens and Anticarcinogens in the Human Diet

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309053919
Total Pages : 434 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Carcinogens and Anticarcinogens in the Human Diet by : National Research Council

Download or read book Carcinogens and Anticarcinogens in the Human Diet written by National Research Council and published by National Academies Press. This book was released on 1996-03-12 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.

A Review of Human Carcinogens

Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (815 download)

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Book Synopsis A Review of Human Carcinogens by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference

Download or read book A Review of Human Carcinogens written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

How Tobacco Smoke Causes Disease

Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Outdoor Air Pollution

Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher : IARC Monographs on the Evaluat
ISBN 13 : 9789283201472
Total Pages : 0 pages
Book Rating : 4.2/5 (14 download)

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Book Synopsis Outdoor Air Pollution by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Outdoor Air Pollution written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risk to Humans, which met in Lyon, 8-15 October 2013."

Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide

Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher :
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by . This book was released on 1999 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sittig's Handbook of Pesticides and Agricultural Chemicals

Author : Richard P. Pohanish
Publisher : William Andrew
ISBN 13 : 1455731579
Total Pages : 1006 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Sittig's Handbook of Pesticides and Agricultural Chemicals by : Richard P. Pohanish

Download or read book Sittig's Handbook of Pesticides and Agricultural Chemicals written by Richard P. Pohanish and published by William Andrew. This book was released on 2014-09-06 with total page 1006 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference handbook provides fully updated chemical, regulatory, health, and safety information on nearly 800 pesticides and other agricultural chemicals. The clear, consistent and comprehensive presentation of information makes Sittig's an essential reference for a wide audience including first responders, environmental and industrial health/safety professionals, the food industry, the agricultural sector and toxicologists. Detailed profiles are provided for each substance listed, including: usage; crop-specific residue limits; hazard ratings for long-term human toxicity; and endocrine disruptor and reproductive toxicity information. Every chemical profile contains references and web links to source information from the EPA, OSHA, the World Health Organization (WHO), and other important advisory and lawmaking bodies. This work is focused on regulated chemicals. The substances covered include pesticides, insecticides, herbicides, fungicides, rodenticides and related agricultural chemicals used on foods grown and produced for both human and animal consumption. These products are organized with common names, chemical synonyms, trade names, chemical formulae, US EPA pesticide codes, EU regulations including Hazard Symbol and Risk Phrases, EINECS, RTECS, CAS, and other unique identifiers so that all who may have contact with, or interest in them can find needed information quickly. - A comprehensive reference for the agricultural sector, food industry, agrochemical manufacturing and distribution sector, and first responders - Brings together a wealth of hazard and response, regulatory and toxicological information in one convenient go-to handbook - Covers US, EU and worldwide regulatory requirements

Solid and Hazardous Waste Management

Author : M.N. Rao
Publisher : Butterworth-Heinemann
ISBN 13 : 0128098767
Total Pages : 346 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Solid and Hazardous Waste Management by : M.N. Rao

Download or read book Solid and Hazardous Waste Management written by M.N. Rao and published by Butterworth-Heinemann. This book was released on 2016-10-27 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid and Hazardous Waste Management: Science and Engineering presents the latest on the rapid increase in volume and types of solid and hazardous wastes that have resulted from economic growth, urbanization, and industrialization and how they have challenged national and local governments to ensure effective and sustainable management of these waste products. The book offers universal coverage of the technologies used for the management and disposal of waste products, such as plastic waste, bio-medical wastes, hazardous wastes, and e-wastes. - Covers both traditional and new technologies for Identifying and categorizing the source and nature of the waste - Provides methods for the safe disposal of municipal solid wastes, plastic waste, bio-medical wastes, hazardous wastes, and e-wastes - Presents technologies that can be used for transportation and processing (including resource recovery) of the waste - Discusses reclamation, reuse, and recovery of energy from MSW

Reducing Environmental Cancer Risk

Author : Suzanne H. Reuben
Publisher : DIANE Publishing
ISBN 13 : 1437934218
Total Pages : 240 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Reducing Environmental Cancer Risk by : Suzanne H. Reuben

Download or read book Reducing Environmental Cancer Risk written by Suzanne H. Reuben and published by DIANE Publishing. This book was released on 2010-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.

Carcinogens, Dna Damage And Cancer Risk: Mechanisms Of Chemical Carcinogenesis

Author : Miriam Christine Poirier
Publisher : World Scientific
ISBN 13 : 981323721X
Total Pages : 391 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Carcinogens, Dna Damage And Cancer Risk: Mechanisms Of Chemical Carcinogenesis by : Miriam Christine Poirier

Download or read book Carcinogens, Dna Damage And Cancer Risk: Mechanisms Of Chemical Carcinogenesis written by Miriam Christine Poirier and published by World Scientific. This book was released on 2018-09-28 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: As chemical exposures and cancer rates increase worldwide, there is a need for students, researchers, public health professionals, and physicians to understand the mechanisms connecting exposure with human cancer risk. This new book is an essential reference, as well as introduction to the field of chemical carcinogenesis, with particular focus on DNA damage as a critical link between exposure and disease, and emphasis on biomarkers associated with cancer risk in humans. In addition to DNA damage, related topics covered include metabolism of selected chemical carcinogens, exposure-induced epigenetic changes, cancer-associated mutations and reduction of DNA damage and cancer risk by chemoprevention. The book is designed to be a comprehensive guide to basic principles, a teaching tool for academics, and a map for the development of protective mechanisms to reduce human cancer risk.

Industrial Ventilation Design Guidebook

Author : Howard D. Goodfellow
Publisher : Academic Press
ISBN 13 : 0128167793
Total Pages : 745 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Industrial Ventilation Design Guidebook by : Howard D. Goodfellow

Download or read book Industrial Ventilation Design Guidebook written by Howard D. Goodfellow and published by Academic Press. This book was released on 2021-06-04 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Industrial Ventilation Design Guidebook, Volume 2: Engineering Design and Applications brings together researchers, engineers (both design and plants), and scientists to develop a fundamental scientific understanding of ventilation to help engineers implement state-of-the-art ventilation and contaminant control technology. Now in two volumes, this reference contains extensive revisions and updates as well as a unique section on best practices for the following industrial sectors: Automotive; Cement; Biomass Gasifiers; Advanced Manufacturing; Industrial 4.0); Non-ferrous Smelters; Lime Kilns; Pulp and Paper; Semiconductor Industry; Steelmaking; Mining. - Brings together global researchers and engineers to solve complex ventilation and contaminant control problems using state-of-the-art design equations - Includes an expanded section on modeling and its practical applications based on recent advances in research - Features a new chapter on best practices for specific industrial sectors

A Review of Human Carcinogens. F. Chemical Agents and Related Occupations

Author : International Agency for Research on Cancer
Publisher : International Agency for Research on Cancer
ISBN 13 :
Total Pages : 636 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis A Review of Human Carcinogens. F. Chemical Agents and Related Occupations by : International Agency for Research on Cancer

Download or read book A Review of Human Carcinogens. F. Chemical Agents and Related Occupations written by International Agency for Research on Cancer and published by International Agency for Research on Cancer. This book was released on 2012-09-24 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 100 compiles information on tumor sites and mechanisms of carcinogenesis. About half of the agents classified in Group 1 were last reviewed more than 20 years ago, before mechanistic studies became prominent in evaluations of carcinogenicity. In addition, more recent epidemiological studies and animal cancer bioassays have demonstrated that many cancer hazards reported in earlier studies were later observed in other organs or through different exposure scenarios. Much can be learned by updating the assessments of agents that are known to cause cancer in humans. Accordingly, IARC has selected A Review of Human Carcinogensto be the topic for Volume 100. It is hoped that this volume, by compiling the knowledge accumulated through several decades of cancer research, will stimulate cancer prevention activities worldwide, and will be a valued resource for future research to identify other agents suspected of causing cancer in humans. Volume 100 was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Metals, particles, and fibres; Radiation; Personal habits and household exposures; Chemical agents and related occupations. Because the scope of Volume 100 is so broad, its Monographs are focused on key information. Each Monograph presents a description of a carcinogenic agent and how people are exposed, critical overviews of the epidemiological studies and animal cancer bioassays, and a concise review of the agent's toxicokinetics, plausible mechanisms of carcinogenesis, and potentially susceptible populations, and life-stages. Details of the design and results of individual epidemiological studies and animal cancer bioassays are summarized in tables. Short tables that highlight key results are printed in Volume 100, and more extensive tables that include all studies appear on the Monographs programe website (http://monographs.iarc.fr/). For a few well-established associations (for example, tobacco smoke and human lung cancer), it was impractical to include all studies, even in the website tables. In those instances, the rationale for inclusion or exclusion of sets of studies is given.

The Carcinogenicity of Metals

Author : Alan B. G. Lansdown
Publisher : Royal Society of Chemistry
ISBN 13 : 1849737193
Total Pages : 449 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis The Carcinogenicity of Metals by : Alan B. G. Lansdown

Download or read book The Carcinogenicity of Metals written by Alan B. G. Lansdown and published by Royal Society of Chemistry. This book was released on 2013-10-31 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book re-evaluates epidemiological and occupational health studies, experimental studies in animals and in vitro experiments relating to the toxicity of 27 metal and metalloid elements for which evidence of carcinogenicity has been presented. Human carcinogenic risk is substantiated in relation to arsenic, beryllium, thorium, chromium, radioactive elements, probably lead, and some nickel and cobalt compounds, and respirable silica particles, but the carcinogenicity of iron, aluminium, titanium, tungsten, antimony, bismuth, mercury, precious metals, and certain related compounds in humans is unresolved. The toxicity and carcinogenicity of each element is specific but correlates poorly with its position in the Periodic Table. Carcinogenicity differs according to the valency of the ion and its ability to interact with and penetrate membranes in target cells and to bind, denature or induce mutations by genotoxic or epigenetic mechanisms. This important text comprehensively examines each of the elements providing detailed information on the carcinogenicity and toxicity and detailing the most up-to-date research in this area. The book is an essential tool for toxicologists, medicinal and biochemists, and environmental scientists working in both industry and academia.

Chemical Carcinogenesis

Author : Trevor M. Penning
Publisher : Springer Science & Business Media
ISBN 13 : 1617379956
Total Pages : 447 pages
Book Rating : 4.6/5 (173 download)

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Book Synopsis Chemical Carcinogenesis by : Trevor M. Penning

Download or read book Chemical Carcinogenesis written by Trevor M. Penning and published by Springer Science & Business Media. This book was released on 2011-03-03 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Pesticides in the Diets of Infants and Children

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309048753
Total Pages : 402 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Pesticides in the Diets of Infants and Children by : National Research Council

Download or read book Pesticides in the Diets of Infants and Children written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.

Cancer Risk Assessment

Author : Ching-Hung Hsu
Publisher : John Wiley & Sons
ISBN 13 : 1118035127
Total Pages : 727 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Cancer Risk Assessment by : Ching-Hung Hsu

Download or read book Cancer Risk Assessment written by Ching-Hung Hsu and published by John Wiley & Sons. This book was released on 2010-12-08 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, mixtures, and nanoparticles. It links these to the basic toxicology and biology of cancer, along with the impacts on regulatory guidelines and standards. By providing insightful perspective, Cancer Risk Assessment helps researchers develop a discriminate eye when it comes to interpreting data accurately and separating relevant information from erroneous.

Handbook of Disability, Work and Health

Author : Ute Bültmann
Publisher : Springer
ISBN 13 : 9783030243333
Total Pages : 0 pages
Book Rating : 4.2/5 (433 download)

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Book Synopsis Handbook of Disability, Work and Health by : Ute Bültmann

Download or read book Handbook of Disability, Work and Health written by Ute Bültmann and published by Springer. This book was released on 2020-07-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a summary of research evidence on links between work, health and disability. Across two sections it summarizes updated knowledge on adverse effects of distinct occupational hazards, and it covers concerns with employment opportunities or restrictions. The handbook delivers an overview of material and psychosocial factors as occupational hazards on working people’s physical or mental health that may result in functional impairment and disability. This knowledge can be instrumental in strengthening efforts of professionals and other stakeholders to promote health-conducive working conditions and prevent work-related disability risks. It also covers concerns with employment opportunities or restrictions of persons with physical or mental health problems and disability. This field of interdisciplinary research has grown with a broad range of solid new findings that can have favorable impact on work disability prevention and the practice of medical and vocational rehabilitation. Prominent experts discuss this evidence for major manifestations of physical and mental health problems and disabilities. As a further innovative feature, this handbook integrates biomedical, psychological, and sociological knowledge on major aspects of the links between work, health and disability. It is therefore of interest to students and professionals in related disciplines, as well as for stakeholders involved in the prevention of work disability and rehabilitation into paid work. In times of an increasingly aging work force with elevated risks of reduced health and work functioning, this knowledge can contribute to turning the threats associated with disability into opportunities. This handbook supports the overall aim of enabling persons with (chronic) health problems and disability to participate in work and social life.