How To Fight Harmful Microbial Bugs And Superbugs

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How to Fight Harmful Microbial Bugs and Superbugs?

Author : Alain Fischer
Publisher : Frontiers Media SA
ISBN 13 : 2889714667
Total Pages : 209 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis How to Fight Harmful Microbial Bugs and Superbugs? by : Alain Fischer

Download or read book How to Fight Harmful Microbial Bugs and Superbugs? written by Alain Fischer and published by Frontiers Media SA. This book was released on 2021-09-01 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evolution of human beings has been shaped to a large extent by microbes. A number of microbes are innocuous or even contribute to our health equilibrium. This is the case of bacteria and viral phages present in our gut. However, several bacteria, viruses, parasites, and fungi are damaging our bodies, causing a number of acute and chronic diseases. Until recently, these bugs represented the main causes of death. Better hygiene, vaccines, antibiotics and other anti-microbial drugs have resulted in a better control or cure of many infections. However, malaria, tuberculosis, and AIDS still represent major threats in several countries and the recent epidemics of Ebola and Zika demonstrate how vulnerable we are to newly emerging viruses. Furthermore, diarrhea and pneumonia caused by bacteria or viruses still kill millions of children worldwide. Most importantly, bacteria resistant to existing antibiotics are multiplying at a high pace and these superbugs are expected to kill more and more people in the coming years. Clearly, we need to develop more effective approaches to tackle bugs and superbugs. Better hygiene and better vaccine coverage must be considered first and education of kids is essential in this respect. This is the main objective of this series of papers published in Frontiers for Young Minds under the heading “How to Fight Harmful Microbial Bugs and Superbugs?”. Another key objective of the collection is to elicit the interest of children for research on innovative anti-microbial therapies and vaccines.

Superbugs

Author : Matt McCarthy
Publisher : Penguin
ISBN 13 : 0735217513
Total Pages : 306 pages
Book Rating : 4.7/5 (352 download)

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Book Synopsis Superbugs by : Matt McCarthy

Download or read book Superbugs written by Matt McCarthy and published by Penguin. This book was released on 2020-06-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Bestseller "An amazing, informative book that changes our perspective on medicine, microbes and our future." --Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity. Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more. The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?

Steering Against Superbugs

Author : Olivier Rubin
Publisher : Oxford University Press
ISBN 13 : 019289949X
Total Pages : 307 pages
Book Rating : 4.1/5 (928 download)

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Book Synopsis Steering Against Superbugs by : Olivier Rubin

Download or read book Steering Against Superbugs written by Olivier Rubin and published by Oxford University Press. This book was released on 2023-04-19 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The societal consequences of antimicrobial resistance (AMR) are severe. They include declining health outcomes from longer illnesses, prolonged stays in hospital, loss of protection for patients undergoing medical procedures, increased health care expenditure, and increased mortality. They also include declining global food security as AMR damages farm animal health and crop yields. Despite AMR being a transboundary crisis, concerted global initiatives that effectively combat AMR have been few and far between. Steering Against Superbugs analyses ways to reduce barriers and create opportunities for coordination. The expert contributions in this volume offer specific and original insights about what global governance of AMR means, and ways to help solve AMR issues. They show that effective governance relies crucially on pursuing local level implementation of key policies, and equitable recognition of solutions across multiple sectors within countries, and across the Global North and South. With the COVID-19 pandemic, societies across the world have been reminded of the devastating consequences of not being able to effectively counter global health threats. AMR is arguably one of the most severe long-term threats to human, animal, and environmental health. There is momentum for global political action around novel and emerging disease threats and Steering Against Superbugs contributes with original and insightful research to inform ongoing and future debates.

Strategies to Overcome Superbug Invasions: Emerging Research and Opportunities

Author : Chopra, Dimple Sethi
Publisher : IGI Global
ISBN 13 : 1799803090
Total Pages : 319 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Strategies to Overcome Superbug Invasions: Emerging Research and Opportunities by : Chopra, Dimple Sethi

Download or read book Strategies to Overcome Superbug Invasions: Emerging Research and Opportunities written by Chopra, Dimple Sethi and published by IGI Global. This book was released on 2021-06-25 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, there has been an upsurge in microbial infections. Extensive and inappropriate usage of antimicrobial drugs in treating infections has led to the evolution of a resistant strain of microorganisms and irreversible immunosuppression in humans. Medical institutions and hospitals require solutions to combat these contagions in order to avoid future epidemics. Strategies to Overcome Superbug Invasions: Emerging Research and Opportunities highlights current research and potential strategies to prevent the emergence and re-emergence of drug-resistant pathogenic microbial strains. The content within this publication examines biosensing, global initiatives, nanomaterials, and alternative therapies. It is designed for microbiologists, biotechnologists, pharmacists, pharmacologists, virologists, formulation scientists, infectious disease specialists, government officials, policymakers, healthcare practitioners, doctors, nurses, hospital directors, researchers, surgeons, and academicians who are seeking research on innovative solutions for multi-drug-resistant infections.

Antibiotic Discoveries and a Century of Creating Superbugs

Author : Doreen E. Szollosi
Publisher : Cambridge Scholars Publishing
ISBN 13 : 1527592359
Total Pages : 285 pages
Book Rating : 4.5/5 (275 download)

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Book Synopsis Antibiotic Discoveries and a Century of Creating Superbugs by : Doreen E. Szollosi

Download or read book Antibiotic Discoveries and a Century of Creating Superbugs written by Doreen E. Szollosi and published by Cambridge Scholars Publishing. This book was released on 2023-03-28 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the pre-antibiotic era, the infections we currently see as relatively minor were sometimes deadly. This book discusses the rise (and sometimes fall) of “wonder drugs” designed to combat infections for which, at the time, there was no cure. However, history has shown us that, when antibiotics are overused, it can ultimately lead to either widespread discontinuation of the antibiotic or a drastic decrease in efficacy, leaving healthcare providers with few or no options for treatment. This book explores the discoveries of the major antibiotic drug classes, and highlights major bacterial strains which have become resistant and now represent difficult-to-treat infections. Barriers to new antibiotic development, as well as novel strategies for treating bacterial infections, are also explored.

Fighting Superbugs

Author : United States. Congress. House. Committee on Armed Services. Oversight and Investigations Subcommittee
Publisher :
ISBN 13 :
Total Pages : 100 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Fighting Superbugs by : United States. Congress. House. Committee on Armed Services. Oversight and Investigations Subcommittee

Download or read book Fighting Superbugs written by United States. Congress. House. Committee on Armed Services. Oversight and Investigations Subcommittee and published by . This book was released on 2010 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Good Germs, Bad Germs

Author : Jessica Snyder Sachs
Publisher : Macmillan + ORM
ISBN 13 : 1429923296
Total Pages : 410 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Good Germs, Bad Germs by : Jessica Snyder Sachs

Download or read book Good Germs, Bad Germs written by Jessica Snyder Sachs and published by Macmillan + ORM. This book was released on 2008-09-30 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making Peace with Microbes Public sanitation and antibiotic drugs have brought about historic increases in the human life span; they have also unintentionally produced new health crises by disrupting the intimate, age-old balance between humans and the microorganisms that inhabit our bodies and our environment. As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"— an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes—which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones—each custom-designed for maximum health benefits.

The Perfect Predator

Author : Steffanie Strathdee
Publisher : Hachette Books
ISBN 13 : 0316418072
Total Pages : 346 pages
Book Rating : 4.3/5 (164 download)

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Book Synopsis The Perfect Predator by : Steffanie Strathdee

Download or read book The Perfect Predator written by Steffanie Strathdee and published by Hachette Books. This book was released on 2019-02-26 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: An electrifying memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. "A memoir that reads like a thriller." -New York Times Book Review "A fascinating and terrifying peek into the devastating outcomes of antibiotic misuse-and what happens when standard health care falls short." -Scientific American Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world. Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure. A nail-biting medical mystery, The Perfect Predator is a story of love and survival against all odds, and the (re)discovery of a powerful new weapon in the global superbug crisis.

Super-Powered Immunity Starts in the Gut

Author : Michelle Schoffro Cook
Publisher : Simon and Schuster
ISBN 13 : 164411741X
Total Pages : 206 pages
Book Rating : 4.6/5 (441 download)

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Book Synopsis Super-Powered Immunity Starts in the Gut by : Michelle Schoffro Cook

Download or read book Super-Powered Immunity Starts in the Gut written by Michelle Schoffro Cook and published by Simon and Schuster. This book was released on 2024-01-09 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: A research-backed guide to healing your gut and boosting immunity • Presents a four-week plan for healing the gut and obtaining—and sustaining—optimum immune system function • Offers methods to assess your gut health, determine if you have a specific problem, and select which healing approach would be best • Shares powerful yet natural remedies centered on probiotics, fermented foods, herbs, essential oils, and nutritional supplements Did you know that 70 percent of the immune system resides in the gut? As Dr. Michelle Schoffro Cook explains, a healthy, microbially balanced gastrointestinal tract is one of the biggest keys to warding off and fighting infectious diseases. In this practical guide, Dr. Cook shares tools and hands-on methods to transform your gut health for greater immunity and well-being. Distilling the most recent research, she explains the connection between GALT (gut-associated lymphoid tissue) and a strong gut-immune relationship. She offers methods to assess your gut health and select which healing approach would be best. She explores some of the main illnesses, conditions, and disorders that afflict the gut and lead to poor immune system performance, including excessive yeast growth, dysbiosis (an imbalanced microbiome where harmful microbes far outnumber the beneficial ones), and excessive gut permeability (which allows dangerous germs, microbes, and toxins to invade the blood stream). Showing how to treat these conditions holistically without damaging and compromising your gut and immune system, Dr. Cook shares powerful yet natural remedies like herbs, essential oils, and nutritional supplements. She looks at the role of probiotics and fermented foods in immunity, providing an extensive examination of how and why they work. She examines new research about particular probiotic strains that are effective against even the most drug-resistant health conditions like MRSA and C. difficile. She explains the often-invisible, immune-depleting damage caused by antibiotic use and what to do immediately if you’re taking antibiotics or have suffered damage from having done so. She also offers a detailed four-week plan for healing the gut and obtaining—and sustaining—optimum immune system function. Explaining all of the necessary research-backed tools and techniques, this guide empowers you to take charge of your gut health, transform your immune system, and achieve vibrant health.

Climate Change and Microbial Diversity

Author : Suhaib A. Bandh
Publisher : CRC Press
ISBN 13 : 1000609642
Total Pages : 285 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Climate Change and Microbial Diversity by : Suhaib A. Bandh

Download or read book Climate Change and Microbial Diversity written by Suhaib A. Bandh and published by CRC Press. This book was released on 2022-08-18 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ongoing global climate change triggered by greenhouse gas growth has had a significant effect on the microbial dynamics of plants and soils. This volume explores the various microbial responses of plants and soils caused directly or indirectly by climate change resulting from rising greenhouse gases and other factors. The book considers the rapidly changing environment and the important role of microbiomes in restoring soil and plant health and in creating sustainable approaches. It discusses the adaptation and mitigation of plants and soils, specifically addressing such topics as biogeochemical processes, antimicrobial resistance, the dynamics of bacteria and fungus in extreme environments, bacterial siderophores for sustainability, and more. The volume also looks at edaphic and regeneration performance of tree species in the temperate forests.

Mechanisms of antibiotic resistance

Author : Jun Lin
Publisher : Frontiers Media SA
ISBN 13 : 2889195260
Total Pages : 226 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Mechanisms of antibiotic resistance by : Jun Lin

Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Your Medical Mind

Author : Jerome Groopman
Publisher : Penguin Books
ISBN 13 : 014312224X
Total Pages : 322 pages
Book Rating : 4.1/5 (431 download)

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Book Synopsis Your Medical Mind by : Jerome Groopman

Download or read book Your Medical Mind written by Jerome Groopman and published by Penguin Books. This book was released on 2012-08-28 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drs. Groopman and Hartzband reveal a clear path for making the right medical choices. Such factors as authority figures, statistics, other patients' stories, technology, and natural healing are key factors that shape choices.

Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria

Author : Attilio Vittorio Vargiu
Publisher : Frontiers Media SA
ISBN 13 : 2889199312
Total Pages : 195 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria by : Attilio Vittorio Vargiu

Download or read book Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria written by Attilio Vittorio Vargiu and published by Frontiers Media SA. This book was released on 2016-08-12 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of antibiotics represented a key milestone in the history of medicine. However, with the rise of these life-saving drugs came the awareness that bacteria deploy defence mechanisms to resist these antibiotics, and they are good at it. Today, we appear at a crossroads between discovery of new potent drugs and omni-resistant superbugs. Moreover, the misuse of antibiotics in different industries has increased the rate of resistance development by providing permanent selective pressure and, subsequently, enrichment of multidrug resistant pathogens. As a result, antimicrobial resistance has now become an urgent threat to public health worldwide (http://www.who.int/drugresistance/documents/surveillancereport/en/). The development of multidrug resistance (MDR) in an increasing number of pathogens, including Pseudomonas, Acinetobacter, Klebsiella, Salmonella, Burkholderia, and other Gram-negative bacteria is a most severe issue. Membrane efflux pump complexes of the Resistance-Nodulation-cell Division (RND) superfamily play a key role in the development of MDR in these bacteria. RND pumps, together with other transporters, contribute to intrinsic and acquired resistance to most, if not all, of the antimicrobial compounds available in our drug arsenal. Given the enormous drug polyspecificity of MDR efflux pumps, studies on their mechanism of action are extremely challenging, and this has negatively impacted both the development of new antibiotics that are able to evade these efflux pumps as well as the design of pump inhibitors. The collection of articles in this eBook, published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy, aims to update the reader about the latest advances on the structure and function of RND efflux transporters, their roles in the overall multidrug resistance phenotype of Gram-negative pathogens, and on strategies to inhibit their activities. A deeper understanding of the mechanisms by which RND efflux pumps, alone or synergistically with other efflux pumps, are able to limit the concentration of antimicrobial compounds inside the bacterial cell, may pave the way for new, more directed, inhibitor and antibiotic design to ultimately overcome antimicrobial resistance by Gram-negatives.

Nature at War

Author : Thomas Robertson
Publisher : Cambridge University Press
ISBN 13 : 1108419763
Total Pages : 399 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Nature at War by : Thomas Robertson

Download or read book Nature at War written by Thomas Robertson and published by Cambridge University Press. This book was released on 2020-04-02 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: "World War II was the largest and most destructive conflict in human history. It was an existential struggle that pitted irreconcilable political systems and ideologies against one another across the globe in a decade of violence unlike any other. There is little doubt today that the United States had to engage in the fighting, especially after the Japanese attack on Pearl Harbor on December 7, 1941. The conflict was, in the words of historians Allan Millett and Williamson Murray, "a war to be won." As the world's largest industrial power, the United States put forth a supreme effort to produce the weapons, munitions, and military formations essential to achieving victory. When the war finally ended, the finale signaled by atomic mushroom clouds over Hiroshima and Nagasaki, upwards of 60 million people had perished in the inferno. Of course, the human toll represented only part of the devastation; global environments also suffered greatly. The growth and devastation of the Second World War significantly changed American landscapes as well. The war created or significantly expanded a number of industries, put land to new uses, spurred urbanization, and left a legacy of pollution that would in time create a new term: Superfund site"--

Missing Microbes

Author : Martin J. Blaser, MD
Publisher : Henry Holt and Company
ISBN 13 : 0805098119
Total Pages : 289 pages
Book Rating : 4.8/5 (5 download)

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Book Synopsis Missing Microbes by : Martin J. Blaser, MD

Download or read book Missing Microbes written by Martin J. Blaser, MD and published by Henry Holt and Company. This book was released on 2014-04-08 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: “In Missing Microbes, Martin Blaser sounds [an] alarm. He patiently and thoroughly builds a compelling case that the threat of antibiotic overuse goes far beyond resistant infections.”—Nature Renowned microbiologist Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the equilibrium and health of our bodies. Now this invisible Eden is under assault from our overreliance on medical advances including antibiotics and caesarian sections, threatening the extinction of our irreplaceable microbes and leading to severe health consequences. Taking us into the lab to recount his groundbreaking studies, Blaser not only provides elegant support for his theory, he guides us to what we can do to avoid even more catastrophic health problems in the future. “Missing Microbes is science writing at its very best—crisply argued and beautifully written, with stunning insights about the human microbiome and workable solutions to an urgent global crisis.”—David M. Oshinsky, author of the Pulitzer Prize-winning Polio: An American Story

Tuberculosis and Superbugs

Author : Ian Wilker
Publisher : Enslow Publishing, LLC
ISBN 13 : 1622930851
Total Pages : 98 pages
Book Rating : 4.6/5 (229 download)

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Book Synopsis Tuberculosis and Superbugs by : Ian Wilker

Download or read book Tuberculosis and Superbugs written by Ian Wilker and published by Enslow Publishing, LLC. This book was released on 2014-07-01 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even though tuberculosis can be successfully treated with antibiotics, it still infects millions of people every year, causing painful, debilitating symptoms and sometimes death. The overuse of antibiotics has lead to the evolution of "superbugs," creating strains of TB and other diseases that are much more difficult to cure. This book investigates the history of TB and other drug-resistant diseases, explains who is most susceptible, and discusses the very real threat of these diseases today.

Viruses Vs. Superbugs

Author : T. Häusler
Publisher : Springer
ISBN 13 : 0230552285
Total Pages : 307 pages
Book Rating : 4.2/5 (35 download)

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Book Synopsis Viruses Vs. Superbugs by : T. Häusler

Download or read book Viruses Vs. Superbugs written by T. Häusler and published by Springer. This book was released on 2016-05-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year thousands of people die from bacteria resistant to antibiotics. Alternative drugs are urgently needed. A surprising ray of hope from the past are viruses that kill bacteria, but not us. Award-winning science journalist Thomas Häusler investigates how these long-forgotten cures may help sick people today.