How Selegiline ((-)-Deprenyl) Slows Brain Aging

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Publisher : Bentham Science Publishers
ISBN 13 : 1608054705
Total Pages : 161 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis How Selegiline ((-)-Deprenyl) Slows Brain Aging by : Joseph Knoll

Download or read book How Selegiline ((-)-Deprenyl) Slows Brain Aging written by Joseph Knoll and published by Bentham Science Publishers. This book was released on 2012-10-12 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book is a reference on Selegiline ((-)-Deprenyl) effects on the brain. Selegiline, described in thousands of research papers, is registered in over 60 countries. At present, more than one hundred preparations containing selegiline circulate in the global market under different brand names. They are widely used in the treatment of Parkinson's disease, Alzheimer's disease, major depression and as a geroprotective / anti-aging drug. ((-)-Deprenyl) selegiline, the first selective inhibitor of B-type MAO which, in contrast to the known MAO inhibitors, did not potentiate the effect of tyramine but inhibited it. the compound could be combined with levodopa in Parkinson's disease without signs of hypertensive reactions. the DATATOP study in the USA revealed that (-)-deprenyl delayed the onset of disability associated with early, otherwise untreated Parkinson's disease. the age-related decay of the supply of the brain with phenylethylamine (PEA), due to the progressive increase of MAO-B activity in the aging brain, and dopamine, due to the better than average decline of the dopaminergic neuronal activity during the postdevelopmental phase of life, are irresistible biochemical lesions of aging. the speed of deterioration of behavioral performances with the passing of time and longevity depends significantly on the pace of the worsening of these lesions. (-)-Deprenyl, increasing the supply of the brain with PEA and dopamine, counteracts this aging process. Maintenance of male rats from sexual maturity until death on ((-)-deprenyl) delays the age-related loss of the capacity to ejaculate, slows the age-related decline of learning ability and prolongs life. In humans, maintenance from sexual maturity on (-)-deprenyl (1 mg daily) is, for the time being, the most promising prophylactic treatment to fight against the age-related decay of behavioral performances, prolonging life, and preventing or delaying the onset of age-related neurodegenerative diseases such as Parkinson's and Alzheimer's. This e-book is a useful reference for graduate medical students, academic researchers in the field of neuropsychopharmacology, neurophysiology and gerontology and professional research groups in commercial organizations manufacturing selegiline preparations.

Neurodegeneration and Neuroprotection in Parkinson's Disease

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Author :
Publisher : Elsevier
ISBN 13 : 0080537413
Total Pages : 239 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Neurodegeneration and Neuroprotection in Parkinson's Disease by :

Download or read book Neurodegeneration and Neuroprotection in Parkinson's Disease written by and published by Elsevier. This book was released on 1996-04-17 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most divers and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological, and therapeutic aspects of chosen research areas.

Rehabilitation in Movement Disorders

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Publisher : Cambridge University Press
ISBN 13 : 110701400X
Total Pages : 263 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Rehabilitation in Movement Disorders by : Robert Iansek

Download or read book Rehabilitation in Movement Disorders written by Robert Iansek and published by Cambridge University Press. This book was released on 2013-05-23 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a broad overview of current rehabilitation approaches, emphasizing the need for interdisciplinary management and focussing on deliverable outcomes.

Parkinson's Disease

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Publisher : Simon and Schuster
ISBN 13 : 0671768190
Total Pages : 276 pages
Book Rating : 4.6/5 (717 download)

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Book Synopsis Parkinson's Disease by : Abraham N. Lieberman

Download or read book Parkinson's Disease written by Abraham N. Lieberman and published by Simon and Schuster. This book was released on 1993-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide for Parkinson patients and their caregivers that addresses the body and the spirit.

Towards New Therapies for Parkinson's Disease

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Author :
Publisher : IntechOpen
ISBN 13 : 9789533074634
Total Pages : 410 pages
Book Rating : 4.0/5 (746 download)

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Book Synopsis Towards New Therapies for Parkinson's Disease by : David Finkelstein

Download or read book Towards New Therapies for Parkinson's Disease written by David Finkelstein and published by IntechOpen. This book was released on 2011-11-02 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinson's disease (PD) is characterised clinically by various non-motor and progressive motor symptoms, pathologically by loss of dopamine producing cells and intraneuronal cytoplasmic inclusions composed primarily of ?-synuclein. By the time a patient first presents with symptoms of Parkinson's disease at the clinic, a significant proportion of the cells in the substantia nigra have already been destroyed. This degeneration progresses despite the current therapies until the cell loss is so great that the quality of normal life is compromised. The dopamine precursor levodopa is the most valuable drug currently available for the treatment of PD. However for most PD patients, the optimal clinical benefit from levodopa decreases around five to six years of treatment. The aim of the chapters of this book is to work towards an understanding in the mechanisms of degeneration and to develop disease modifying therapies.

Healthy Brain Aging: Evidence Based Methods to Preserve Brain Function and Prevent Dementia, An issue of Clinics in Geriatric Medicine

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455700320
Total Pages : 180 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Healthy Brain Aging: Evidence Based Methods to Preserve Brain Function and Prevent Dementia, An issue of Clinics in Geriatric Medicine by : Abhilash K. Desai

Download or read book Healthy Brain Aging: Evidence Based Methods to Preserve Brain Function and Prevent Dementia, An issue of Clinics in Geriatric Medicine written by Abhilash K. Desai and published by Elsevier Health Sciences. This book was released on 2010-03-17 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue examines what is a healthy aging brain and covers preventive measures for succesful cognitive aging. Topics covered include: A road map to healthy aging brain; Cardiovascular risk factors, cerebrovascular disease burden and healthy aging brain; Healthy aging brain: Impact of head injury, alcohol and environmental toxins; Healthy aging brain: What has sleep go to do with it?; Endocrine aspects of healthy aging brain; Healthy aging brain: Role of exercise and physically active lifestyle; Healthy aging brain: Role of nutrition and nutritional supplements; Healthy aging brain: Role of cognitive reserve, cognitive stimulation and cognitive exercises; Healthy aging brain: Impact of positive and negative emotions; Dementia risk predictor. Are we there yet?; Potential future neuroprotective therapies for neurodegenerative disorders and stroke; Healthy aging brain: Importance of promoting resilience and creativity.

Clinical Handbook for the Management of Mood Disorders

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Publisher : Cambridge University Press
ISBN 13 : 1107024633
Total Pages : 429 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Handbook for the Management of Mood Disorders by : J. John Mann

Download or read book Clinical Handbook for the Management of Mood Disorders written by J. John Mann and published by Cambridge University Press. This book was released on 2013-05-09 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a one-stop evidence-based guide to the management of all types of mood disorders.

The Case of the Frozen Addicts

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Publisher : IOS Press
ISBN 13 : 1614993327
Total Pages : 264 pages
Book Rating : 4.6/5 (149 download)

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Book Synopsis The Case of the Frozen Addicts by : J.W. Langston

Download or read book The Case of the Frozen Addicts written by J.W. Langston and published by IOS Press. This book was released on 2013-12-02 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the summer of 1982, hospital emergency rooms in the San Francisco Bay Area were suddenly confronted with mysteriously “frozen” patients – young men and women who, though conscious, could neither move nor speak. Doctors were baffled, until neurologist J. William Langston, recognizing the symptoms of advanced Parkinson’s disease, administered L-dopa – the only known effective treatment – and “unfroze” his patient. Dr. Langston determined that this patient and five others had all used the same tainted batch of synthetic heroin, inadvertently laced with a toxin that had destroyed an area of their brains essential to normal movement. This same area, the substantia nigra, slowly deteriorates in Parkinson’s disease. As scientists raced to capitalize on this breakthrough, Dr. Langston struggled to salvage the lives of his frozen patients, for whom L-dopa provided only short-term relief. The solution he found lay in the most daring area of research: fetal-tissue transplants. The astonishing recovery of two of his patients garnered worldwide press coverage, helped overturn federal restrictions on fetal-tissue research, and offered hope to millions suffering from Parkinson’s, Alzheimer’s, and other degenerative brain disorders. This is the story behind the headline – a spellbinding account that brings to life the intellectual excitement, ethical dilemmas, and fierce competitiveness of medical research. This new updated edition of the classic neurological mystery tale, “The Case of the Frozen Addicts,” illuminates how the solution to a baffling mystery of the brain’s chemistry opened a new frontier in medicine and restored life to people without hope. “It begins with a series of quixotic discoveries, escalates to providing possible solutions for one of humanity’s most intractable medical problems, and then catapults the reader into the center of America’s hottest political arena – abortion and fetal sanctity. Bravo! A brilliant read.” – Laurie Garrett, author of The Coming Plague “[Langston and Palfreman] weave a highly readable and spellbinding medical detective tale... It is as absorbing as a good mystery, as entertaining as an exciting novel, and as enlightening as a good biography.” – Stanley Fahn, New England Journal of Medicine “I could not put it down... it is the lives of the ‘frozen addicts’ themselves – and the fullness with which this is presented – which makes the whole thing overwhelming.” – Oliver Sacks

Keto Smart!: Heal Your Brain and Body With the Ten-Step Action Plan Scientifically Proven to Prevent or Reverse Obesity, Memory Loss, Alzheimer's, Diabetes, Autoimmunity, Cancer, and Heart Disease

Download Keto Smart!: Heal Your Brain and Body With the Ten-Step Action Plan Scientifically Proven to Prevent or Reverse Obesity, Memory Loss, Alzheimer's, Diabetes, Autoimmunity, Cancer, and Heart Disease PDF Online Free

Author :
Publisher : Lulu.com
ISBN 13 : 0359071309
Total Pages : 276 pages
Book Rating : 4.3/5 (59 download)

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Book Synopsis Keto Smart!: Heal Your Brain and Body With the Ten-Step Action Plan Scientifically Proven to Prevent or Reverse Obesity, Memory Loss, Alzheimer's, Diabetes, Autoimmunity, Cancer, and Heart Disease by : Y.L. Wright M.A.

Download or read book Keto Smart!: Heal Your Brain and Body With the Ten-Step Action Plan Scientifically Proven to Prevent or Reverse Obesity, Memory Loss, Alzheimer's, Diabetes, Autoimmunity, Cancer, and Heart Disease written by Y.L. Wright M.A. and published by Lulu.com. This book was released on 2018-10-27 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get Smart with KETO SMART! Heal your brain and heal your body with this easy KETO SMART program. KETO SMART is packed with secrets to improve your memory and thinking with simple instructions that you can easily follow. Learn how to radically improve the health of your brain, so that you can enjoy life to the max at any age. Your heart, arteries, and everything else will improve as well. The KETO SMART 10-step protocol is MUCH more than just following a ketogenic diet. The KETO SMART 10-step protocol is a comprehensive program of self-healing. Follow the KETO SMART ten easy action steps, and soon your thinking mind will become as penetrating as the depths of a pristine alpine lake on a quiet sunny morning. The goal of this book is to guide you through the maze of interconnected problems. Every step helps, but you only get the gold ring of health by following the complete treatment plan. It isnÕt hard if you know what to do. It is impossible if you don't.

Lexicon of Psychiatry, Neurology, and the Neurosciences

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781724685
Total Pages : 1138 pages
Book Rating : 4.7/5 (246 download)

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Book Synopsis Lexicon of Psychiatry, Neurology, and the Neurosciences by : Frank J. Ayd

Download or read book Lexicon of Psychiatry, Neurology, and the Neurosciences written by Frank J. Ayd and published by Lippincott Williams & Wilkins. This book was released on 2000 with total page 1138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its thoroughly updated Second Edition, Dr. Ayd's highly acclaimed Lexicon is an indispensable desk reference for anyone working in psychiatry, neurology, or the underlying basic neurosciences. It provides succinct, detailed, and easily accessible definitions for the entire range of terms currently used in these fields, including drug categories, receptors, and the sites and mechanisms affected by pharmacologic treatments. This edition reflects the most recent developments in genetics and in psychopharmacology, including new drugs and current concepts on drug-drug interactions. Dr. Ayd has added over 1,000 new terms and rewritten nearly half of the entries in the original edition. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC

An Essay on the Shaking Palsy

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Author :
Publisher :
ISBN 13 :
Total Pages : 86 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis An Essay on the Shaking Palsy by : James Parkinson

Download or read book An Essay on the Shaking Palsy written by James Parkinson and published by . This book was released on 1817 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bio-Identical Hormones and Telomerase

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Author :
Publisher : iUniverse
ISBN 13 : 1450255760
Total Pages : 376 pages
Book Rating : 4.4/5 (52 download)

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Book Synopsis Bio-Identical Hormones and Telomerase by : Dr. Hiroshi Demura

Download or read book Bio-Identical Hormones and Telomerase written by Dr. Hiroshi Demura and published by iUniverse. This book was released on 2011-08-25 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: As we grow older, many of us experience a tremendous amount of frustration because something inside us doesnt work the way it used to. Nutrition experts tell us to eat certain kinds of food some claim free radicals are the sole cause of aging, and that the only way to longevity is through antioxidant supplements. Fitness gurus tell us the only answer is exercise. When we do exercise or go on a diet, we feel a little betterbut not much, and not the way we felt when we were younger. We exercise or diet twice as much to stay at the same place, and even that is a challenge. The story has been the same throughout history, so we wonder if we should continue to fight the battle, or if we should just learn to grow old gracefully. Improvements in medical technology and new knowledge about exercise, nutrition, and rest are all part of the solution to remaining young and healthy. However, we continue to see some people who do not take particularly good care of themselves, yet are aging more gentlyand we know instinctively that parts of the anti-aging puzzle must still be missing.

How to Use Herbs, Nutrients, and Yoga in Mental Health Care

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Author :
Publisher : W. W. Norton & Company
ISBN 13 : 0393707695
Total Pages : 465 pages
Book Rating : 4.3/5 (937 download)

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Book Synopsis How to Use Herbs, Nutrients, and Yoga in Mental Health Care by : Richard P. Brown

Download or read book How to Use Herbs, Nutrients, and Yoga in Mental Health Care written by Richard P. Brown and published by W. W. Norton & Company. This book was released on 2012-02-20 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: All you need to know about herbs, nutrients, and yoga for enhancing mental health. Many physicians and therapists agree that herbs and mind-body practices enhance health, but many more are reluctant to integrate them into their clinical work because of a lack of training or, given how long it takes to master the use of hundreds of different herbs, a lack of time. But the trend is clear: clients and consumers alike want control over their health care choices, making the time ripe for a practical resource that guides both the clinician and the consumer on complementary and alternative medicine (CAM). This book answers that call. Three noted experts in integrative medicine, Drs. Brown, Gerbarg, and Muskin, demystify the complexities of alternative mental health care, giving readers a comprehensive yet accessible guidebook to the best treatment options out there. From mood, memory, and anxiety disorders to ADD, sexual enhancement issues, psychotic disorders, and substance abuse, every chapter covers a major diagnostic category. The authors then present a range of complementary and alternative treatments-including the use of herbs, nutrients, vitamins, nootropics, hormones, and mind-body practices- that they have found to be beneficial for various conditions within each category. For example, B complex vitamins and folate have been shown to help with depression; omega-3 fatty acids can offer relief for bipolar sufferers; coherent and resonant breathing techniques-used by Buddhist monks-induce healthy alpha rhythms in the brain to relieve anxiety; the elderly can boost their memory by taking the ancient medicinal herb Rhodiola rosea; and those with chronic fatigue syndrome can find comfort in acupuncture and yoga. Focusing on evidence-based approaches, the research, the authors' clinical experience, and the potential risks and benefits of each treatment are carefully examined. Brown, Gerbarg, and Muskin have distilled an otherwise daunting field of treatment down to its basics: their overriding approach is to present the CAM methods that are most practical in a clinical setting, easy to administer, and low in side effects. With helpful summary tables at the end of each chapter, clinical pearls, and case vignettes interspersed throughout, this is a must-have resource for all clinicians and consumers who want the best that alternative medicine has to offer.

Non-Motor Symptoms of Parkinson's Disease

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0199684243
Total Pages : 517 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Non-Motor Symptoms of Parkinson's Disease by : K. Ray Chaudhuri

Download or read book Non-Motor Symptoms of Parkinson's Disease written by K. Ray Chaudhuri and published by Oxford University Press, USA. This book was released on 2014 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future. Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.

Neurogerontology

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Publisher : Springer Publishing Company
ISBN 13 : 0826117171
Total Pages : 389 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Neurogerontology by : James F. Willott, PhD

Download or read book Neurogerontology written by James F. Willott, PhD and published by Springer Publishing Company. This book was released on 1999-07-25 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurogerontology tells the story of how the aging brain affects all aspects of cognition and physical performance. It comprehensively links the principles and substance of neuroscience with gerontology and psychology. Written largely from a behavioral neuroscience perspective, Neurogerontology explores the functional relationships between the central nervous system and psychological phenomena of aging, including perception, arousal, learning, cognition, and motor behavior. Willot emphasizes healthy aging, but dementia and other pathological conditions are discussed when relevant. This evidence-based approach to the neuroscience of aging makes this a valuable reference for professionals, as well as an informative textbook for students in gerontology courses.

Aging and Human Longevity

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461220068
Total Pages : 291 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Aging and Human Longevity by : M.-F. Schulz-Aellen

Download or read book Aging and Human Longevity written by M.-F. Schulz-Aellen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: The proportion of elderly people continues to increase in the western world-nearly a quarter of the population will be over 65 years by the year 2050. Since aging is accompanied by an increase in diseases and by a deterioration in well-being, finding solutions to these social, medical and psychological problems is necessarily a major goal for society. Scientists and medical practitioners are therefore faced with the urgent task of increasing basic knowledge of the biological processes that cause aging. More resources must be put into this research in order to achieve better understanding of the cellular mechanisms that underlie the differences in life span between species and to answer the difficult questions of why some individuals age more quickly than others, and why some develop liver problems, some have heart problems, and others brain problems. The results of such a wide program of research will provide important information about the causes of many life-threatening and/ or debilitating diseases of old age; it will help find ways to prevent some of the ailments that result from aging, and it may well lead to discoveries enabling the prolongation of human life.

Youth Extension A to Z

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Author :
Publisher : Ronin Publishing
ISBN 13 : 1579511120
Total Pages : 151 pages
Book Rating : 4.5/5 (795 download)

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Book Synopsis Youth Extension A to Z by : Beverly A. Potter

Download or read book Youth Extension A to Z written by Beverly A. Potter and published by Ronin Publishing. This book was released on 2011-09-30 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a group, baby boomers are heading rapidly into their "golden years," and there's little doubt that they won't go lightly. But is the process really irrevocable and irreversible? With more financial resources than any other demographic, and the knowledge gained simply by living, boomers are in the best position to at least delay the aging process. This practical guide offers a wealth of ways to do that. Dr. Beverly Potter, who has written numerous books on enhancing one's lifestyle, includes but goes beyond anti-aging and life extension. Youthfulness, she says, is characterized by vigor, flexibility, bounciness, good health, physical shapeliness, beauty, curiosity, and mental acuity — all of which can be achieved through the regimens the book describes. Potter takes a multifaceted approach, incorporating both current science and proven techniques into a program that stresses vitamins, nutrients, healthful foods, and supplements; activities and lifestyles; ways of thinking; sexual techniques; brain fitness training; and more.