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Host Defense Against Intracellular Pathogens
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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis Janeway's Immunobiology by : Kenneth M. Murphy
Download or read book Janeway's Immunobiology written by Kenneth M. Murphy and published by . This book was released on 2008 with total page 887 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Host Defenses to Intracellular Pathogens by : Toby K. Eisenstein
Download or read book Host Defenses to Intracellular Pathogens written by Toby K. Eisenstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject matter of this volume was the basis for a confer ence held in Philadelphia in June, 1981, and is an important one in the contemporary area of how the host interacts with micro organisms. In conception, it grew out of a graduate course entitled, "The Infectious Process," which has been taught in the Department of Microbiology and Immunology at Temple University School of Medicine during the past twelve years. This course has explored the broad areas of mechanisms of microbial pathogenesis and host resistance by in-depth consideration of selected models of experimental infection and immunity, as well as the clinical literature. It is noteworthy that there is no adequate text for this material, as the subject matter naturally crosses a wide spectrum of traditional disciplinary lines, encompassing topics as diverse as the mechanisms of action of bacterial toxins, the role of complement and antibody in phagocytosis, and the importance of cross-reacting bacterial polysaccharide antigens in vaccine development. A major portion of the course has always considered "cellular immunity" as it applies to host defenses to intracellular pathogens. It is in this area that the necessity for amalgamation of information from different disciplines is most evident, for one must be intimately concerned with the interactions between the microbe and the phagocyte, both before and after specific immune recognition.
Book Synopsis Innate Host Defense Against Intracellular Pathogens by :
Download or read book Innate Host Defense Against Intracellular Pathogens written by and published by . This book was released on 2013 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Host Defense Against Intracellular Pathogens by : Belinda Hsiu Jung Tan
Download or read book Host Defense Against Intracellular Pathogens written by Belinda Hsiu Jung Tan and published by . This book was released on 2004 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Host Defenses and Immunomodulation to Intracellular Pathogens by : Ward E. Bullock
Download or read book Host Defenses and Immunomodulation to Intracellular Pathogens written by Ward E. Bullock and published by Springer. This book was released on 2014-11-14 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This conference was held under the sponsorship of the Eastern Pennsylvania Branch of the American Society for Microbiology, as one in a continuing series of Basic Science Symposia. The untiring volunteer effects of the members of the Symposium Committee are deeply appreciated. The Bureau of Laboratories of the Pennsylvania Department of Health was a cosponsor and generously provided staff and secretarial services to handle the difficult task of registration. The Department of Microbiology and of Microbiology and Immunology at the five medical schools in Philadelphia -- Temple University School of Medicine, Medical College of Pennsylvania, Thomas Jefferson University, Hahnemann University and the University of Pennsylvania -- were academic cosponsors, and the support of the Chairpersons and the faculties are gratefully acknowledged.
Book Synopsis Trained Immunity-based Vaccines by : Jose Luis Subiza
Download or read book Trained Immunity-based Vaccines written by Jose Luis Subiza and published by Frontiers Media SA. This book was released on 2021-08-25 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Book Synopsis Opportunistic Intracellular Bacteria and Immunity by : Lois J. Paradise
Download or read book Opportunistic Intracellular Bacteria and Immunity written by Lois J. Paradise and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Opportunistic, intracellular bacterial infections are at the forefront of research because of the challenges they present to immunocompromised patients. In this volume, the pathogenesis and immune reaction of these intracellular infections is featured, as are the most typical problems related to antimicrobial chemotherapy, and current approaches to their solution. Individual chapters set the pace for research on pathogenic and immune reactions to such infections as, mycobacterium tuberculosis, legionella pneumophila, chlamydia trachomatis and brucella.
Book Synopsis Innate Immune Cell Recruitment and Host Defense in Response to Intracellular Bacterial Infection by : William Jerome Bunce Vincent
Download or read book Innate Immune Cell Recruitment and Host Defense in Response to Intracellular Bacterial Infection written by William Jerome Bunce Vincent and published by . This book was released on 2017 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interactions between invading pathogens and host immune cells that respond to infection is a long and involved relationship. In particular, a class of pathogens have evolved to not only evade clearance by the cells of the innate immune system, but do so by manipulation of the host cytosol. This proximity has led to the intricate co-evolution of clearance and evasion mechanisms of the host and pathogen, respectively. How these interactions are carried out in the cellular immune response is the subject of this dissertation. In Chapter 2, I build a localized infection model for one such pathogen, Listeria monocytogenes, using the transparent zebrafish larval host. Using this model, I demonstrate the functional presence of a conserved innate immune sensing pathway, the inflammasome, that surveils the cytosol for the presence of bacterial flagellin. Upon optimal inflammasome activation, the host is protected from lethal infection, and I show that macrophages are the crucial host cell population in this defense. In Chapter 3, I characterize L. monocytogenes' utilization of the host actin network demonstrating live imaging of this interaction for the first time in vivo. Once L. monocytogenes is localized within the cytosol, it slows down macrophage motility, although in an actin independent manner. In Chapter 4, I develop a model to study the recruitment and resolution of leukocytes during concurrent wounding and infection. This model demonstrates both beneficial and detrimental leukocyte responses, and provides evidence that the immune responses to bacterial infection and wounding are separable programs during early stages of immune response. Taken together, I have shown that macrophages are a crucial part of host defense downstream of inflammasome activation, that macrophages activate other cell autonomous responses during their interaction with intracellular pathogens, and that macrophage-neutrophil interactions can be critical in determining a beneficial or detrimental response to infection. These findings highlight the intricate and close evolution of host immune cells and intracellular pathogens, as well as the critical nature of inflammatory balance during immune responses.
Book Synopsis Host Defense to Intracellular Pathogens. [Proceedings of a Conference, June 10-12, 1981..., Philadelphia] by :
Download or read book Host Defense to Intracellular Pathogens. [Proceedings of a Conference, June 10-12, 1981..., Philadelphia] written by and published by . This book was released on 1983 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Military Strategies for Sustainment of Nutrition and Immune Function in the Field by : Institute of Medicine
Download or read book Military Strategies for Sustainment of Nutrition and Immune Function in the Field written by Institute of Medicine and published by National Academies Press. This book was released on 1999-05-13 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
Book Synopsis Toll-Like Receptors (TLRs) and Innate Immunity by : Stefan Bauer
Download or read book Toll-Like Receptors (TLRs) and Innate Immunity written by Stefan Bauer and published by Springer Science & Business Media. This book was released on 2007-12-11 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.
Download or read book The Immune Response written by Tak W. Mak and published by Academic Press. This book was released on 2005-11-11 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. Current and thorough 30 chapter reference reviewed by luminaries in the field Unique ‘single voice' ensures consistency of definitions and concepts Comprehensive and elegant illustrations bring key concepts to life Provides historical context to allow fuller understanding of key issues Introductory chapters 1-4 serve as an ‘Immunology Primer' before topics are discussed in more detail
Download or read book Bacterial Pathogenesis written by and published by Academic Press. This book was released on 1998-07-01 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow Covers safety aspects, detection, identification and speciation Includes techniques for the study of host interactions and reactions in animals and plants Describes biochemical and molecular genetic approaches Essential methods for gene expression and analysis Covers strategies and problems for disease control
Book Synopsis Lectin in Host Defense Against Microbial Infections by : Shie-Liang Hsieh
Download or read book Lectin in Host Defense Against Microbial Infections written by Shie-Liang Hsieh and published by Springer Nature. This book was released on 2020-03-09 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically presents the latest research on lectins, covering all the major topics in the field, including the heterocomplex of lectins and Toll-like receptors, protective versus pathogenic functions in connection with microbial infections, and novel strategies for enhancing host immunity against infectious diseases caused by viruses, bacteria, and fungi. Lectins are a large group of glycan-binding proteins that recognize diverse glycan and non-glycan structures expressed on prokaryotic and eukaryotic cells, and are vital to cell-cell interactions, the attachment of microbes to host cells, and the recognition and activation of immune responses to exogenous and endogenous danger signals. The composition and structure of microbes are complex and include numerous ‘pathogen-associated molecular patterns’ or ‘damage-associated molecular patterns’. As such, microbes’ interactions with immune cells activate multiple innate immunity receptors and produce distinct inflammatory reactions, which can be protective to contain microbial invasion, or pathogenic to cause tissue damage and shock syndrome in the host. The book shares lessons learned from state-of-the art research in this field, highlights the latest discoveries, and provides insightful discussions on lectin-mediated inflammatory reactions, while also outlining future research directions.
Book Synopsis Leishmaniases as Re-emerging Diseases by : Farhat Afrin
Download or read book Leishmaniases as Re-emerging Diseases written by Farhat Afrin and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.
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