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Hormonal Steroids
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Book Synopsis Hormonal Steroids Biochemistry, Pharmacology, and Therapeutics by : L Martini
Download or read book Hormonal Steroids Biochemistry, Pharmacology, and Therapeutics written by L Martini and published by Elsevier. This book was released on 2012-12-02 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal Steroids: Biochemistry, Pharmacology, and Therapeutics, Volume I focuses on various research on steroids and their biological and medical involvements. Comprised of 60 chapters, the book presents the literature of various authors who have conducted research on the relationship between hormonal steroids and biochemistry, pharmacology, and therapeutics. The discussions start with the identification of steroids with hormone-like activities. This discussion includes the nature, compositions, properties, possible uses, and reactions of these hormones when exposed to different conditions and controlled environments. The book then proceeds with discussions on synthesis and metabolism of hormonal steroids. These discussions are supported by graphical representations, reviews, recommendations, and methodologies. The book then explains the control of synthesis and release of steroid hormones. This part notes the relationship of renal and adrenal hormones; the control and production of corticosterone; neurosecretion and control of the pituitary gland; and release of ovulating hormones. The book also highlights the mechanism of steroid action, noting the probable interrelationships of steroids, nonsteroids, intermediary metabolism, and inflammation. Various research are presented on the possible clinical applications of steroids. The text is a vital reference for readers who are interested in the study of hormones.
Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.
Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Book Synopsis Orthobiologics by : Giuseppe Filardo
Download or read book Orthobiologics written by Giuseppe Filardo and published by Springer Nature. This book was released on 2021-12-02 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.
Book Synopsis Hormonal Steroids by : V. H. T. James
Download or read book Hormonal Steroids written by V. H. T. James and published by Elsevier. This book was released on 2013-10-22 with total page 1073 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal Steroids presents the proceedings of the Sixth International Congress on Hormonal Steroids, held in Jerusalem, Israel in September 1982. The book covers a wide range of topics on the field of hormonal steroids research. The topics discussed include the history of steroid-protein interaction; enzyme induction by estrogen; steroids and the immune system; correlative morphological and biochemical investigations on the stromal tissue of the human prostate; analysis of intact steroid conjugates by secondary ion mass spectrometry (including fabms) and by gas chromatography; and the role of lipoproteins in steroidogenesis by human luteinized granulosa cells in culture. Biochemists, pathologists, pharmacologists, and medical and pharmaceutical researchers will find the book a good source of insight.
Book Synopsis Steroid-protein Interactions by : Ulrich Westphal
Download or read book Steroid-protein Interactions written by Ulrich Westphal and published by Springer. This book was released on 1971 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the story of steroid-protein interactions as one investigator sees it. Following the general concept of this monograph series, it emphasizes the results and interpretations obtained in the author's laboratory, and is therefore a subjective account. Recognizing, how ever, that the discussion of the subject would be incomplete if the material were limited to one scientist's work, the essential achieve ments of other investigators have been incorporated. An effort has thus been made to give a balanced presentation and to enable the reader to see in perspective the varied facets of the interactions between steroids and proteins. Since this is the first comprehensive treatment of the topic, it seems appropriate to go to the roots, and try to find out how it all started. The first chapters, therefore, take the reader to the laboratories of those who very early conceived the significance of the attachment of dyes, drugs, and other conspicuous molecules to those colloids called proteins. The discovery of the steroid hormones set the stage for meaningful investigation of their interaction with proteins of various origins and functions - a process which is continuing today with increasing vigor.
Book Synopsis Steroid Hormone Regulation of the Brain by : Kjell Fuxe
Download or read book Steroid Hormone Regulation of the Brain written by Kjell Fuxe and published by Elsevier. This book was released on 2013-10-22 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid Hormone Regulation of the Brain focuses on the advancement of knowledge of the properties of brain steroid receptors and steroid target nerve cells, including the actions of gonadal steroids, adrenocortical steroids, and androgenic steroids on the brain. The selection features the work of authors who have inspiringly conducted extensive studies on the action of steroid hormones. The book starts with discussions that point out that steroid hormones not only function through intracellular steroid receptors, but possibly through steroid membrane actions as well. Studies to support this claim are presented. As to the action of steroid hormones on presynaptic transmitter mechanisms, the book suggests that adrenocortical and gonadal steroids can create alterations in noradrenaline, adrenaline, and dopamine levels and turnover within the hypothalamus and preoptic area. The effects of catecholestrogens on the brain are also elaborated. A contribution to this paper stresses that estrogens have antidopaminergic action in the extrapyramidal system. This idea is identified through a series of behavioral experiments and measurements of the levels of striatal acetylcholine. This selection is recommended to scientists interested in studying the effect of hormones on the brain.
Book Synopsis Anabolic-Androgenic Steroids by : Charles D. Kochakian
Download or read book Anabolic-Androgenic Steroids written by Charles D. Kochakian and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume was planned to provide a comprehensive survey of the role of the anabolic-androgenic steroids in the vital economy exclusive of the androgenic (sexual) functions. It seemed appropriate to bring together all of this information in an organized fashion in one volume at this time not only to serve as a source of information but also to indicate and suggest areas that need further exploration. The anabolic action of the steroid hormones has gone through a period of great activity in both basic and clinical research. A complete understanding of the manifold anabolic effects still remains to be elucidated and the art of clinical application is only gradually becoming apparent. This volume should be useful not only to the experienced investigator in both basic and clinical research but also for the novice. Furthermore, it should serve as a source of information for the careful use of these steroids in certain metabolic diseases. These steroids have had wide clinical application with variable results. In many instances further careful exploration is suggested. Other instances have demonstrated varying degrees of usefulness.
Book Synopsis Steroid Hormone Action by : Malcolm G. Parker
Download or read book Steroid Hormone Action written by Malcolm G. Parker and published by IRL Press. This book was released on 1993 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid Hormone Action is a comprehensive overview of the molecular mechanisms by which these hormones regulate the expression of specific target genes. The book covers the structure of steroid receptors, transcriptional activation and repression, and also contains chapters on steroid bindingproteins and steroidogenesis. Steroid receptors represent one of the best characterized transcription factors so that the book will be of general interest to Molecular Biologists studying eucaryotic gene regulation. Chapters on the mechanisms of action of steoid antagonists and defective receptorsin target cells will be of particular interest to Endocrinologists and Clinicians. In such a rapidly progressing field it is difficult to keep up with all the literature but this book, written by international experts, focuses on the most important advances that have been made recently.
Book Synopsis An Introduction to Neuroendocrinology by : Richard E. Brown
Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
Book Synopsis Research on Steroids by : M. Finkelstein
Download or read book Research on Steroids written by M. Finkelstein and published by Elsevier. This book was released on 2013-10-22 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on Steroids contains the proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones. The papers explore the production, chemical characterization, and metabolism of steroid hormones and their interactions with proteins. Topics range from the action of estradiol in vitro to water-soluble metabolites of estrogens, transport of steroids by proteins, and immunological aspects of steroid hormones. The binding of steroids by tissue proteins is also discussed, along with the use of specific plasma proteins for the determination of steroids. This volume is comprised of 38 chapters and begins with an overview of the general aspects of steroid-protein interaction, followed by a discussion on quantitative studies of steroid binding proteins; aromatization of testosterone by human placenta enzymes; relationship between plasma binding and 5a-reduction of testosterone; cortisol-binding capacity of plasma transcortin in subjects treated with various anabolic steroids; and plasma testosterone binding capacity and estrogen excretion in normal and pathological pregnancies. Subsequent chapters deal with the interaction between estrogenic and carcinogenic substances in the rat mammary gland; influence of steroid production on serum albumin in Cushing's syndrome; and nuclear estradiol binding proteins in the uterus. This book will be of interest to biochemists, biologists, and physiologists.
Download or read book Steroids written by Aharon W. Zorea and published by Bloomsbury Publishing USA. This book was released on 2014-04-25 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough, balanced examination of the controversies on the therapeutic and non-therapeutic use of steroids that covers both legal medical therapy and illegal performance enhancement. The discussions regarding the ethical, medical, and social controversies surrounding steroid use are as heated as the drugs themselves are powerful. Steroids comprehensively addresses the separate debates over steroid use in therapeutic medical treatments, sports performance enhancement, and cosmetic lifestyle choices. The contents provide balanced coverage of the complex positive and negative implications involved with using these "ingredients of youth" to evade the common ailments of old age and to overcome some of the limitations of natural biology. This book will be invaluable to students of not only health and exercise sciences, sports and sport-related fields, and medical science, but also those researching social and ethical questions involved with the use of steroids in related fields. For example, the book may be used by sociology students investigating social aspects of sports, health policy, and public role models; psychology students focusing on the role of self-image and mental health; and political science students researching public health policy.
Book Synopsis Steroid and Sterol Hormone Action by : Thomas C. Spelsberg
Download or read book Steroid and Sterol Hormone Action written by Thomas C. Spelsberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to focus attention on recent developments in steroid and sterol hormone action. Many authors have generously contributed to the book. As a result, there is a great diversity of opinion! A majority of the chapters deal with steroid or sterol hormone receptors. This is not meant to imply that receptor-mediated mechanisms are the sole or even the most important mechanisms by which steroid hormones act in the cell. There is wealth of evidence showing that other, non-receptor events, are important also. Steroid hormone recep tor research and the study of nuclear events mediated by steroids are presently the most intensely studied aspects of sterol hormone action and our selection of topics reflects this trend. We have also included chapters on vitamin 0 sterols and thyroid hormone in the book, as there is pood evidence that these hormones act in a manner similar to other classical steroids. 1 IMMUNOCHARACTERIZATION OF THE NUCLEAR ACCEPTOR SITES FOR THE AVIAN OVIDUCT PROGESTERONE RECEPTOR A. GOLDBERGER, M. HORTON, T. C. SPELSBERG Department of Biochemistry and Molecular Biology, Mayo Clinic and Mayo Graduate School of Medicine, Rochester, MN 55905 INTRODUCTION It is well known that steroid hormones, certain vitamins and sterols, enter target cells and bind to specific protein receptors in the cyto plasm or nucleus (1-4). This binding is saturable, high affinity, and steroid specific.
Book Synopsis Steroid Dynamics by : Gregory Pincus
Download or read book Steroid Dynamics written by Gregory Pincus and published by Academic Press. This book was released on 2013-10-22 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid Dynamics compiles papers presented at the Symposium on the Dynamics of Steroid Hormones held in Tokyo, in May 1965. This compilation discusses the effect of LH and ACTH on production and excretion of testosterone in vivo, estrogen receptors in target tissues, and influence of morphine on corticoid production. The binding of steroids to follicular fluid proteins, conjugation and excretion of aldosterone, and active cholesterol pool for corticodogenesis in the rat adrenal are also elaborated. This book likewise covers the dynamics of steroid hormone distribution in the body, biosynthesis of steroids in testicular tissue in vitro, and isotopic dilution methods for the estimation of rates of secretion of the steroid hormones. This publication is a good reference for endocrinologists, biochemists, and medical practitioners interested in steroid dynamics.
Book Synopsis Anabolic Steroids by : Patrick Lenehan
Download or read book Anabolic Steroids written by Patrick Lenehan and published by CRC Press. This book was released on 2003-06-12 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anabolic steroids have traditionally been controversial in the sporting arena. Today, research indicates a dramatic increase in the use of anabolic steroids and other performance-enhancing drugs outside of competitive sports. With evidence of widespread steroid abuse among the general population, health professionals are citing the emergence of an
Book Synopsis Physical Properties of the Steroid Hormones by : Lewis L. Engel
Download or read book Physical Properties of the Steroid Hormones written by Lewis L. Engel and published by Elsevier. This book was released on 2013-10-22 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pure and Applied Biology, Volume 3: Physical Properties of the Steroid Hormones illustrates the efficiency of methodology for the solution of problems of isolation, identification and quantitative determination of the physical properties of steroids. This volume is composed of five chapters, and begins with a survey of the factors that influence the partition coefficient of steroid hormone, along with the consideration of the types and preparation of solvent systems for determination. The next chapter describes the chromatographic mobilities of steroids using several chromatographic methods, such as paper chromatography. A chapter presents the ultraviolet absorption data on structural correlations of steroids. Another chapter highlights the conversion of a steroid into a fluorescent compound through the steroid-acid interaction mechanism. The final chapter deals with the selective absorption spectra of steroids in concentrated sulfuric acid without heating. This book is directed primarily toward steroid chemists and researchers.
Book Synopsis Development of Responsiveness to Steroid Hormones by : Alvin M. Kaye
Download or read book Development of Responsiveness to Steroid Hormones written by Alvin M. Kaye and published by Elsevier. This book was released on 2013-10-22 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of Responsiveness to Steroid Hormones is a collection of papers presented at the Bat-Sheva Seminar of the same name which was held in Rehovot, Israel, on October 18-26, 1978 and sponsored by the Bat-Sheva de Rothschild Foundation for the Advancement of Science in Israel in cooperation with The Weizmann Institute of Science. Contributors explore how the steroid receptor complex modulates transcription of RNA and cover topics ranging from the sequential acquisition of responsiveness to estrogen in the rat uterus to the ontogeny of steroid receptors in the guinea pig. This book is comprised of 29 chapters and begins with a review of estrogen and estrogen effects in rat uterus and pituitary in culture. The embryonic chick Müllerian duct and several fetal guinea pig organs are then considered, followed by discussions on mammalian and chick liver, multi-hormonal control in rat liver; progesterone and decidualization; and rat mammary gland in culture. Glucocorticoids in developing pancreas, lung, and liver are examined, along with ecdysteroids in both locusts and Drosophila. Refractoriness is exemplified by gonadotropin action in the ovary. The remaining chapters deal with the role of steroid hormone receptors in brain development; the neural trigger for ovulation; aromatization and development of responsiveness of the brain to gonadal steroids; and neuroendocrine correlates of female-offspring interaction in maternal rats. This monograph will be of value to physiologists, biologists, and biochemists.
Book Synopsis Gene Regulation by Steroid Hormones by : A.K. Roy
Download or read book Gene Regulation by Steroid Hormones written by A.K. Roy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last two decades endocrinological research has taken a definite tum toward biochemistry and molecular biology. This has resulted in a new discipline called' 'molecular endocrinology. " Studies on the mechanism of hormone action have continued to make headlines with fundamental discov eries in receptor action and gene regulation. Recently the insect endocrino logists have also begun to explore the molecular mechanism of steroid hor mone action taking advantage of the vast number of Drosophila mutants, the library of Drosophila gene, and several well-characterized cell-lines. The availability ofthe recombinant DNA technology has provided a truly revolu tionary tool in the hands of the molecular endocrinologists. "Gene Regula tion by Steroid Hormones" is compiled and presented in this frontier spirit, and we hope that this volume will serve not only the active investigators in the field but will also be very useful to students and researchers with a gen eral interest in regulatory biology. The book is an offshoot of the Conference on Molecular Mechanism of Steroid Hormone Action held at the Meadow Brook Mansion of Oakland University in the fall of 1978. We wish to acknowledge the financial assist ance from the National Science Foundation and Oakland University. The conferees will never forget the warmest hospitality of Dr. LOWELL EKLUND and his staff at the Meadow Brook center and we also wish to express per sonal gratitude to many of our students and colleagues for helping us to make the conference a great success.
