Horizons in Cancer Research. Volume 59

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ISBN 13 : 9781634831109
Total Pages : 203 pages
Book Rating : 4.8/5 (311 download)

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Book Synopsis Horizons in Cancer Research. Volume 59 by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research. Volume 59 written by Hiroto S. Watanabe and published by . This book was released on 2015 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original results on the leading edge of cancer research. Topics discussed include imaging of chondrosarcoma; novel nutrient mixtures inhibiting chondrosarcoma invasion and metastasis parameters; defective estrogen signaling is the highest risk for breast cancer; review of the cancer genomic landscape; reprogramming of metabolic pathways and cancer stem like cells; promising natural products as anti-cancer agents against neuroblastoma; oncofertility; and molecular mechanisms involved in myelodysplastic syndromes.

Horizons in Cancer Research. Volume 87

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.8/5 (911 download)

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Book Synopsis Horizons in Cancer Research. Volume 87 by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research. Volume 87 written by Hiroto S. Watanabe and published by . This book was released on 2024-07-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Horizons in Cancer Research

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (649 download)

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Download or read book Horizons in Cancer Research written by and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Horizons in Cancer Research

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Publisher : Nova Science Publishers
ISBN 13 : 9781620819081
Total Pages : 321 pages
Book Rating : 4.8/5 (19 download)

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Book Synopsis Horizons in Cancer Research by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by Nova Science Publishers. This book was released on 2011 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Horizons in Cancer Research

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Publisher : Nova Science Publishers
ISBN 13 : 9781622571666
Total Pages : 178 pages
Book Rating : 4.5/5 (716 download)

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Book Synopsis Horizons in Cancer Research by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by Nova Science Publishers. This book was released on 2012 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original research results on the leading edge of cancer. Topics discussed include the etiology and treatment of gallbladder cancer; HPV vaccine and cervical cancer; docetaxel therapy and applications; metastatic cancer pain management for the bone, spine and liver; the effects of cytoskeletal structure change induced by docetaxel on gene expression; nutrition and breast cancer; and docetaxel's effect on ovarian function and in the management of patients with head and neck squamous cell carcinoma.

Horizons in Cancer Research. Volume 85

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.8/5 (869 download)

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Book Synopsis Horizons in Cancer Research. Volume 85 by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research. Volume 85 written by Hiroto S. Watanabe and published by . This book was released on 2023-04-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the latest developments in cancer research.

Horizons in Cancer Research

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ISBN 13 : 9781536132977
Total Pages : pages
Book Rating : 4.1/5 (329 download)

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Download or read book Horizons in Cancer Research written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Horizons in Cancer Research. Volume 73

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ISBN 13 : 9781536162738
Total Pages : 0 pages
Book Rating : 4.1/5 (627 download)

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Book Synopsis Horizons in Cancer Research. Volume 73 by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research. Volume 73 written by Hiroto S. Watanabe and published by . This book was released on 2019-10-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Horizons in Cancer Research. Volume 73, after the identification of some small subgroups with a strong biological-molecular identity, the current evidence regarding the prognostic factors of patients with non-eradicable metastatic disease are examined. The goal is to discuss disease subgroups, which may sometimes provide conditions for decisions that are less compliant with current clinical practice and help define new stratification criteria for patients enrolled in prospective studies.Following this, the authors summarize the current knowledge on breast cancer with an introduction on the traditional markers used in the diagnosis of this disease, followed by an account of the emerging markers.Next, the underlying mechanisms of DNA replication, damage and repair are discussed. Further, RAD51 is proposed as a potential means of managing chemoresistant cancers. Certain drugs and strategies can sensitize chemotherapy via impacting on RAD51, which can be developed as chemotherapy modulators. The authors also discuss multiple myeloma, an incurable malignant tumor of plasma cells of the bone marrow, which is the most common primary neoplasm arising in bone. It causes approximately 1% of cancer-related deaths and is the 2nd most common hematological malignancy in the western world.Later, this collection discusses the prevalence and types of infectious complications that patients with multiple myeloma face, as well as present and emerging therapeutic approaches.The concluding study indicates proteins that have a promising future as new anticancer drugs, in conjunction with the in vitro and/or in vivo effects of these bioactive proteins derived from plants.

Horizons in Cancer Research

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Publisher : Nova Science Publishers
ISBN 13 : 9781634854634
Total Pages : 0 pages
Book Rating : 4.8/5 (546 download)

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Book Synopsis Horizons in Cancer Research by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by Nova Science Publishers. This book was released on 2016-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original results on the leading edge of cancer research. Chapter One summarizes what is currently known regarding the epigenetic regulation of osteosarcoma pathways and oncogenes, as well as clinical trials of drugs that exert epigenetic regulation. Chapter Two critically discusses the role of ECM-dependent signaling in osteosarcoma progression. Chapter Three illustrates the harmful effects of ultraviolet radiation exposure by focusing on photocarcinogenesis. Chapter Four examines the psychology of sunscreen use and outlines the key psychological factors associated with sunscreen use. Chapter Five reviews the cellular and molecular mechanism of Regulatory T cells (Tregs) and Transforming Growth Factor-β mediating cervical cancer development. Chapter Six examines the affect of the American cranberry extract on expression of insulin-like growth factor-I and insulin-like growth factor binding proteins in human prostate cancer cells in vitro. Chapter Seven discusses the design of synthetic peptides to specifically interfere the papillomavirus binding factor/14-3-3beta binding to restore papillomavirus binding factor apoptotic functions. Chapter Eight examines brain development using correlations between Diffusion Kurtosis and neurite orientation dispersion and density imaging (NODDI) in neonates and young children. Chapter Nine highlights the opportunities that are available to prevent the late effects related to stress and fears, emphasizing the importance of teaching patients resiliency and how to cope.

Horizons in Cancer Research. Volume 78

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ISBN 13 : 9781536187731
Total Pages : 248 pages
Book Rating : 4.1/5 (877 download)

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Book Synopsis Horizons in Cancer Research. Volume 78 by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research. Volume 78 written by Hiroto S. Watanabe and published by . This book was released on 2020-11-04 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compilation begins by discussing the common pediatric brain tumors, their key oncogenic drivers and signaling pathways. An update on the clinical trials against druggable targets is also provided.An outline of the metabolizing pathways in cancer and the mode of action of aerobic glycolysis in cancer cells is presented, also highlighting the roles of nanotechnology in energy-based cancer therapies.The authors review recent studies that characterize the specific mechanisms involved in mediating -tocotrienol reversal of epithelial-to mesenchymal transition in malignant breast cancer cells.The cytotoxic effects of Mannich bases derived from kojic acid on A375 human malignant melanoma are discussed and MRC-5 human lung cell lines are investigated using a sulphorhodamine B assay.Additionally, the cytotoxic effects and mechanisms displayed by metformin are assessed, alone or in combination with other agents. A better understanding of metformin-induced metabolic changes could aid in the discovery of new drugs, enhancing the efficacy of current melanoma therapeutics.In closing, the authors explore the way in which physical activity and exercise are negatively correlated to most type of cancers, as exercise shares common underlying metabolic pathways with those of some bioactive food compounds, such as polyphenols.

Horizons in Cancer Research. Volume 72

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ISBN 13 : 9781536158120
Total Pages : 0 pages
Book Rating : 4.1/5 (581 download)

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Book Synopsis Horizons in Cancer Research. Volume 72 by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research. Volume 72 written by Hiroto S. Watanabe and published by . This book was released on 2019-07-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first chapter of Horizons in Cancer Research. Volume 72 discusses the Ewing's sarcoma family of tumors, including classic Ewing's sarcoma of the bone, extraskeletal Ewing's sarcoma and malignant peripheral primitive neuroectodermal tumor of both bone and soft tissue.The following chapter discusses Primary Ewing's sarcoma of the base of the tongue, particularly its diagnosis and treatment.Additionally, the authors examine dual proteasome and histone deacetylase6 inhibitor, dual MDM2 and histone deacetylase inhibitor, and dual bromodomain-containing protein 4 and histone deacetylase inhibitor.The authors go on to examine the genes and proteins involved in mitosis that are proposed as candidates for biomarkers in different types of cancer (colon, lung, prostate, breast and ovarian, among others).The penultimate chapter reviews the published evidence of aromatase inhibitors in breast cancer risk reduction. The recommended patient populations for the use of aromatase inhibitors, expected benefits, adverse effects and monitoring parameters are addressed.The transcription factor and chromatin structure-related aspects of cancer treatment are the focus of the final chapter.

Horizons in Cancer Research

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ISBN 13 : 9781536170733
Total Pages : 212 pages
Book Rating : 4.1/5 (77 download)

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Book Synopsis Horizons in Cancer Research by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by . This book was released on 2020-03-28 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opening chapter of this compilation extensively reviews scientific literature analyzing new molecular targets, ongoing research and future perspectives in the management of gastroenteropancreatic neuroendocrine neoplasms, a rare group of pathologically and clinically heterogeneous tumors. The significance of PI3K pathway components in lung cancer progression are highlighted, as well as possible therapeutic targets that can be explored in an effort to control the disease. Following this, the authors assess the contributions of flavin-containing monooxygenases 3 along with cytochrome P450 enzymes in Bu metabolic pathways, and analyze their effects on Bu kinetics. The role of the pro-tumorigenic cytokines and the significance of dysregulated notch signaling in the progression of colonic inflammation and carcinogenic transformation is also discussed. The current concepts of nutritional oncology in head and neck cancer patients are revised through a systematic literature search. Significant malnutrition has been reported due to several factors, such as a reduced dietary intake due to dysphagia and odynophagia, or catabolic factors secreted by the head and neck tumors. Lastly, an overview of cervical cancer screening around the world is provided. In the United States, a combination of HPV-testing and cytology method, the HPV-test-alone, and cytology-alone are widely performed.

Horizons in Cancer Research

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ISBN 13 : 9781536199178
Total Pages : 0 pages
Book Rating : 4.1/5 (991 download)

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Book Synopsis Horizons in Cancer Research by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by . This book was released on 2021-07-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume presents seven chapters detailing recent progress in the field of cancer research. Chapter One explores the application of robotic surgery to radical cystectomy, highlighting patient selection, surgical approach, perioperative and oncologic outcomes as well as some areas of controversy in the literature. Chapter Two describes the principles of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy procedures with its potential risks for patients and staff. Chapter Three discusses findings related to ISG15 and protein ISGylation, and their association with interferon signaling in cancer. Chapter Four describes the potential for MCF-7 cells to curb or counteract breast cancer. Chapter Five discusses the potential of emerging technologies in breast conserving treatment. Chapter Six reviews the current literature surrounding the basis of employing the immune system for the treatment of the various non-melanoma skin cancers (NMSC), discusses approved immunotherapies for each type of NMSC as well as indications for use, and synthesizes ongoing investigational studies of immunomodulatory agents for these diseases. Finally, Chapter Seven discusses the use of gene therapy in management of squamous cell carcinoma.

Horizons in Cancer Research

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Publisher : Nova Science Publishers
ISBN 13 : 9781536105124
Total Pages : 0 pages
Book Rating : 4.1/5 (51 download)

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Book Synopsis Horizons in Cancer Research by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by Nova Science Publishers. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original results on the leading edge of cancer research. Chapter One presents an overview of the opportunities and challenges that influence the participation of personalised approach of giving the right drug at the right dose to the right patient. Chapter Two examines malignant mesothelioma. Chapter Three reviews the role of heat-shock proteins and chaperonins in the pathogenesis and progression of cancer. Chapter Four discusses the biosynthesis of LeX family glycosphingolipids and its gene regulation. Chapter Five summarises how chromosome segregation is accurately controlled and how spindle assembly checkpoint (SAC) monitors this process to maintain segregation fidelity. Chapter Six reviews significant novel findings and the early clinical development of a CD26-targeted therapy for malignant pleural mesothelioma (MPM), and advances that can lead to a more hopeful future for MPM patients. Chapter Seven reviews the pathophysiology and novel treatment strategies in management of peripheral T-Cell lymphoma. Chapter Eight discusses the confirmation behind a role for metformin in cancer therapy and its prospective molecular mechanisms of action. Chapter Nine highlights the role Ganoderma lucidum and its constituents in cancer signaling. Chapter Ten studies the footprint of Ganoderma lucidum in receptor tyrosine kinases.

Horizons in Cancer Research. Volume 75

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ISBN 13 : 9781536181555
Total Pages : 258 pages
Book Rating : 4.1/5 (815 download)

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Book Synopsis Horizons in Cancer Research. Volume 75 by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research. Volume 75 written by Hiroto S. Watanabe and published by . This book was released on 2020-08-11 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Horizons in Cancer Research. Volume 75 analyses the strategic actions taken by the UK in the fight against cancer, reviewing the key investments and funding made available in the country.Following this, the authors discuss how efficient targeting of thioredoxin with compounds and proper knowledge of their mechanism of action may be an efficacious therapeutic intervention for cancer.This compilation goes on to xplore the otologic complications secondary to radiotherapy for nasopharyngeal cancer cases to provide a clinical perspective on this issue.An extensive review of the published studies about metastatic colorectal cancer kinetics and changes of growth curves under the pressure of pharmacological treatments is presented, and variables related to tumor cell kinetics derived from radiologic evaluations are discussed.The authors propose a new post treatment cancer care involving the systemic administration of nanomolar concentrations of drag-reducing polymers that aims to avoid metastasis following cancer surgery.A study is carried out to compare the molecular mechanism of cytochrome P450 enzyme family members on breast cancer, as well as to compare the distinct biological processes with each other.This compilation closes with a guide for researchers concerning preserving the heterogeneity of breast cancer cell lines in terms of either isolation, selection or culture method models in order to understand the limitations of various methods.

Horizons in Cancer Research

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ISBN 13 : 9781536109443
Total Pages : 0 pages
Book Rating : 4.1/5 (94 download)

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Book Synopsis Horizons in Cancer Research by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by . This book was released on 2017-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original results on the leading edge of cancer research. Chapter One provides a comprehensive discussion to address the potential benefits of myricetin on cancer, diabetes, and neurodegenerative disease. It also discusses the underlined mechanism involved in the biological action of myricetin. Chapter Two discusses the clinical significance of vasculogenic mimicry. Chapter Three studies bacterial toxins as a direct cause of cancer. Chapter Four examines the immunological aspect of stroma in ovarian cancer. Chapter Five focuses on immune checkpoint inhibitors in the treatment of solid tumors. Chapter Six provides a review of targeting non-coding mitochondrial RNAs in gynecological and urinary malignancies. Chapter Seven explores the NF-κB signaling pathway, and its targeting in human cancer treatment. Chapter Eight analyses the circadian rhythm and skin cancer prevention. The final section of this book is a short commentary on melanoma.

Horizons in Cancer Research

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ISBN 13 : 9781611224092
Total Pages : pages
Book Rating : 4.2/5 (24 download)

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Book Synopsis Horizons in Cancer Research by : Hiroto S. Watanabe

Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: