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Hla From Benchtop To Bedside
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Book Synopsis HLA from Benchtop to Bedside by : A. Bradley Eisenbrey
Download or read book HLA from Benchtop to Bedside written by A. Bradley Eisenbrey and published by Academic Press. This book was released on 2021-01-05 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: HLA from Benchtop to Bedside provides the reader with a comprehensive, concise and thoroughly up-to-date book on all aspects of the HLA system, including new techniques and methodologies. Each chapter begins with bullet point lists of principle learning points, including comprehensive references and validated links to international resources. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this book is ideal for organ and stem cell transplant professionals, histocompatibility laboratory professionals and staff, medical residents and fellows on transplant services, medical students, and students in clinical laboratory science. The book's author, Dr. Arthur Bradley Eisenbrey, is an experienced transplant pathologist who has held significant academic and leadership positions in the field. Reviews current knowledge surrounding the HLA system Covers current methodologies and utilization of histocompatibility testing Authored by a leader in the field of histocompatibility and transfusion medicine
Book Synopsis Handbook of HLA Typing Techniques by : Kam M. Hui
Download or read book Handbook of HLA Typing Techniques written by Kam M. Hui and published by CRC Press. This book was released on 2020-10-07 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an authoritative collection of HLA phenotyping and genotyping techniques to be used at the bench level and as a reference. It includes detailed methodologies, notes on the interpretation of tests, reference material, and appendices.
Book Synopsis The HLA Complex in Biology and Medicine by : Narinder K Mehra
Download or read book The HLA Complex in Biology and Medicine written by Narinder K Mehra and published by Boydell & Brewer Ltd. This book was released on 2010-11-26 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics.
Download or read book Human Leukocyte Antigen (HLA) written by and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunosuppression written by Xuehui He and published by BoD – Books on Demand. This book was released on 2020-12-09 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our immune system is equipped with a series of defence mechanisms to recognise and respond to non-self molecules. Although essential for fighting off infections and preventing cancers, destructive immune responses pose a considerable challenge in autoinflammation and transplantation. Currently available immunosuppressants help to control destructive immune responses. However, management of side-effects of lifelong immunosuppression, including cancer development and reduced survival, remain major problems. For this reason, an increasing amount of interest is directed towards the natural specific regulatory mechanism of the immune system. A better understanding of these mechanisms holds the key. This book presents a comprehensive overview of immune suppression in transplantation, cancer and viral infections. Chapters cover modulation of Treg as well as the new era of immunotherapy.
Download or read book Stem Cells written by Ariff Bongso and published by World Scientific. This book was released on 2011 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology. This book is important as it is comprehensive and covers all aspects of stem cell biology, from basic research to clinical applications. It will have 33 chapters written by renowned stem cell scientists worldwide. It will be up-to-date and all the chapters include self-explanatory figures, color photographs, graphics and tables. It will be easy to read and give the reader a complete understanding and state of the art of the exciting science and its applications.
Book Synopsis Nurses Making Policy by : Rebecca Patton
Download or read book Nurses Making Policy written by Rebecca Patton and published by Springer Publishing Company. This book was released on 2014-11-13 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: Print+CourseSmart
Book Synopsis CD1- and MR1-restricted T Cells in Antimicrobial Immunity by : S.M. Mansour Haeryfar
Download or read book CD1- and MR1-restricted T Cells in Antimicrobial Immunity written by S.M. Mansour Haeryfar and published by Frontiers Media SA. This book was released on 2016-01-21 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell-mediated immunity to extracellular and intracellular microbes has been traditionally linked to CD4+ and CD8+ T cells that recognize pathogen-derived peptides in the context of major histocompatibility complex (MHC) class II and class I molecules, respectively. Recent progress in our understanding of early host defense mechanisms has brought ‘unconventional’, innate-like T cells into the spotlight. These are a heterogeneous population of non-MHC-restricted T cells that exhibit ‘memory-like’ properties and mount emergency responses to infection. They may directly detect and destroy infected cells, but are best known for their ability to regulate downstream effector cells including but not limited to conventional T cells. Innate-like T cells include among others CD1-restricted natural killer T (NKT) cells and MR1-restricted mucosa-associated invariant T (MAIT) cells. NKT cells recognize lipid antigens, and MAIT cells were recently demonstrated to respond to microbe-derived vitamin B metabolites. However, much remains to be learned about the antigen specificity range of these cells, their activation mode and their true potentials in immunotherapeutic applications. Like in many other areas of biology, uncertainties and controversies surrounding these cells and some of the experimental models, techniques and reagents employed to study them have brought about excitement and sometimes hot debates. This Special Topic was launched to provide updated reviews on protective and/or pathogenic roles of NKT and MAIT cells during infection. Leading experts discuss current controversies, pressing questions and the challenges that lie ahead for the advancement of this intriguing and rapidly evolving area of immunology. Unlike MHC, CD1 and MR1 display very limited polymorphism. Therefore, NKT and MAIT cells may be considered attractive targets for various diseases in diverse human populations. The potential benefits of NKT cell- and MAIT cell-based vaccination and treatment strategies in infectious diseases is an important subject that is also covered in this Topic.
Download or read book Index Medicus written by and published by . This book was released on 2001-10 with total page 1464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis Transplantation Immunology: Methods and Protocols by : Kayla Streep
Download or read book Transplantation Immunology: Methods and Protocols written by Kayla Streep and published by . This book was released on 2020-09-22 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transplantation refers to the process of moving cells, tissues or organs from one part of the body to another, whether within the same person, or between a donor and a recipient. It is usually a life-saving intervention and is a major operation. However, the transplanted tissue or organ may be rejected by the immune system. Rejection is an adaptive immune response of the body that can occur due to the mechanisms of cellular immunity or humoral immunity. Different transplanted tissues favor different rejection mechanisms. Acute rejection occurs in all transplants unless immunosuppression has been achieved. An exception to this is transplantation between identical twins. Hyperacute rejection response sets in within minutes after a transplant, which if unattended may trigger a systemic inflammatory response syndrome. Rapid clumping, particularly the agglutination of red blood cells, is a common risk in kidney transplants. Chronic rejection can arise when there is a long-term loss of function in the transplanted organ. This loss in function arises due to fibrosis of the blood vessels of the transplanted tissues. This is responsible for the long-term morbidity witnessed in lung-transplant recipients. Transplant rejection can be lowered by using immunosuppressant drugs after transplantation and by prior determination of the molecular similitude between donor and recipient. This book provides comprehensive insights into the field of transplantation immunology. It presents researches and studies performed by experts across the globe on the methods and protocols of transplantation. It is a vital tool for all researching and studying this field.
Book Synopsis Next Generation Sequencing by : Jerzy Kulski
Download or read book Next Generation Sequencing written by Jerzy Kulski and published by BoD – Books on Demand. This book was released on 2016-01-14 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.
Download or read book HLA and Disease written by Robert Lechler and published by . This book was released on 1994 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text describes the genetics and products of the HLA region and their relationship to diseases including diabetes, rheumatoid arthritis and SLE. The statistical principles relevant to the design and interpretation of HLA and disease studies are presented in simple and accessible language.
Book Synopsis The Immunology of Sepsis – Understanding Host Susceptibility, Pathogenesis of Disease, and Avenues for Future Treatment by : Luregn J. Schlapbach
Download or read book The Immunology of Sepsis – Understanding Host Susceptibility, Pathogenesis of Disease, and Avenues for Future Treatment written by Luregn J. Schlapbach and published by Frontiers Media SA. This book was released on 2020-08-19 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Download or read book Taurine 10 written by Dong-Hee Lee and published by Springer. This book was released on 2017-08-28 with total page 1181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taurine 10 contains original articles and critical reviews based on the oral and poster presentations of XX International Taurine Meeting held in Seoul, Korea in May 2016. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.
Book Synopsis Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia by : Masahiro Kizaki
Download or read book Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia written by Masahiro Kizaki and published by Springer. This book was released on 2015-11-05 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development. Included are therapeutic implications, diagnosis, and prognosis for understanding and facilitating daily practice in the management of patients with CML. Understanding of the pathogenesis and therapy of hematological malignancies such as CML has grown significantly in recent years. This development owe much to the progress in molecular biology and now makes a major contribution to diagnosis and to treatment that pharmacologically targets the molecular events of CML. Molecular targeting therapy with newly developed agents such as small molecules and antibodies for hematological malignancies are being discovered after years of research. Some of these, including tyrosine kinase inhibitors such as imatinib, nilotinib, and dasatinib, lead to increased survival rates and improved therapies. With the opinion leaders of basic and clinical research in the field as authors, this book reviews recent advances in the biology of CML.
Book Synopsis Viral Infections of Humans by : Alfred S. Evans
Download or read book Viral Infections of Humans written by Alfred S. Evans and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have confirmed the important role of these viruses in common respiratory illnesses of children and adults. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. Chapter 8, Cytomegalovirus: Sections on pathogenesis of CMV in relation to organ transplantation and mononucleosis, as well as sections on the risk and features of con genital infection and disease, have been expanded. There are encouraging preliminary results with a live CMV vaccine, but the questions of viral persistence and oncogenicity require further evaluation.
Book Synopsis Aptamers for Medical Applications by : Yiyang Dong
Download or read book Aptamers for Medical Applications written by Yiyang Dong and published by Springer Nature. This book was released on 2021-03-25 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines comprehensively the main medical uses of aptamers, from diagnosis to therapeutics in fourteen chapters. Pioneering topics covered include aptamer pharmaceuticals, aptamers for malign tumors, aptamers for personalized therapeutics and aptamers for point-of-care testing. The book offers an essential guide for medical scientists interested in developing aptamer-based schemes for better theranostics. It is therefore of interest for not only academic researchers, but also practitioners and medical researchers in various fields of medical science, medical research and bio-analytical chemistry.
