Hla And Disease Associations

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HLA and Disease Associations

Author : J.L. Tiwari
Publisher : Springer Science & Business Media
ISBN 13 : 1461385458
Total Pages : 492 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis HLA and Disease Associations by : J.L. Tiwari

Download or read book HLA and Disease Associations written by J.L. Tiwari and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man. In the past, many genetic polymorphisms have been suspected to be associated with diseases. The most extensively studied markers are blood groups, enzymes, and serum proteins. A comprehensive account of published studies, totalling approximately 1,000, of these markers is available in a book by Mourant et al.

HLA and Disease Associations

Author : Jawahar L. Tiwari
Publisher :
ISBN 13 : 9783540960812
Total Pages : 472 pages
Book Rating : 4.9/5 (68 download)

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Book Synopsis HLA and Disease Associations by : Jawahar L. Tiwari

Download or read book HLA and Disease Associations written by Jawahar L. Tiwari and published by . This book was released on 1985 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

HLA in Health and Disease

Author : Robert Lechler
Publisher : Academic Press
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis HLA in Health and Disease by : Robert Lechler

Download or read book HLA in Health and Disease written by Robert Lechler and published by Academic Press. This book was released on 2000-05-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and definitive work succeeds and expands on the highly successful HLA and Disease published in 1994. This new edition has been updated, redesigned and reorganised into three sections making it an invaluable reference. The introductory section summarises current knowledge on the structure, function, genetics and evolution of the HLA system. It clarifies its complex and ever changing nomenclature and discusses the mechanisms underlying disease associations with HLA alleles. The second section deals with the importance of HLA in the context of different clinical specialities. Individual chapters describe the association between HLA polymorphism and each disease. The final section features chapters on current laboratory practice in histocompatibility and tissue typing. HLA in Health and Disease is essential reading for basic and clinical researchers working in immunology and immunogenetics, transplantation medicine and autoimmunity. It will also be of interest to anyone in the fields of rheumatology, diabetology, nephrology, allergy, dermatology, neurology, endocrinology, cancer biology, respiratory medicine, haematology, molecular biology and biochemistry. Key Features Structure, function and genetics of HLA HLA nomenclature Evolution of HLA polymorphisms HLA associations in arthritis and rheumatology, renal disease, neurology, diabetes and endocrinology, gastroenterology, respiratory disease, ophthalmology, infections, dermatology and psychiatry HLA and organ transplantation Serological and PCR-based methods in HLA typing Cellular techniques in testing histocompatibility Edited and written by an international panel of experts in the field

HLA and Disease

Author : Robert Lechler
Publisher :
ISBN 13 :
Total Pages : 210 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis HLA and Disease by : Robert Lechler

Download or read book HLA and Disease written by Robert Lechler and published by . This book was released on 1994 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text describes the genetics and products of the HLA region and their relationship to diseases including diabetes, rheumatoid arthritis and SLE. The statistical principles relevant to the design and interpretation of HLA and disease studies are presented in simple and accessible language.

HLA and Disease, An Issue of the Clinics in Laboratory Medicine

Author : Julio Delgado
Publisher : Elsevier Health Sciences
ISBN 13 : 0323642438
Total Pages : pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis HLA and Disease, An Issue of the Clinics in Laboratory Medicine by : Julio Delgado

Download or read book HLA and Disease, An Issue of the Clinics in Laboratory Medicine written by Julio Delgado and published by Elsevier Health Sciences. This book was released on 2018-11-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine, edited by Drs. Julio Delgado and Eszter Lazar-Molnar, will focus on HLA and Disease. Topics include, but are not limited to, The potential impact of NGS in HLA and disease association studies, HLA typing by NGS, HLA Antibody Testing: Evolution and Challenges, Diversity of killer cell immunoglobulin-like receptors and disease, Technical Aspects of Crossmatching in Transplantation, HLA Markers in Celiac Disease, HLA Associations in Drug Hypersensitivity Reactions, HLA in BMT, Post-transplant monitoring, HLA epitope matching in transplantation, and Molecular Testing in Post-Transplant Monitoring.

HLA and Disease

Author : Werner E. Braun
Publisher :
ISBN 13 : 9781351073226
Total Pages : 148 pages
Book Rating : 4.0/5 (732 download)

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Book Synopsis HLA and Disease by : Werner E. Braun

Download or read book HLA and Disease written by Werner E. Braun and published by . This book was released on 2017 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the topic of the HLA antigen system. Chapters discuss topics such as; animal studies, the possible mechanisms of HLA and disease associations, statistical and genetic considerations, the clinical use of HLA typing, as well as the current status of HLA and disease associations.

Hla and Disease

Author : Braun
Publisher : CRC Press
ISBN 13 : 9781315894126
Total Pages : 147 pages
Book Rating : 4.8/5 (941 download)

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Book Synopsis Hla and Disease by : Braun

Download or read book Hla and Disease written by Braun and published by CRC Press. This book was released on 2017-12-13 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the topic of the HLA antigen system. Chapters discuss topics such as; animal studies, the possible mechanisms of HLA and disease associations, statistical and genetic considerations, the clinical use of HLA typing, as well as the current status of HLA and disease associations.

HLA-disease Associations

Author : Christine Therese Stier
Publisher :
ISBN 13 :
Total Pages : 226 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis HLA-disease Associations by : Christine Therese Stier

Download or read book HLA-disease Associations written by Christine Therese Stier and published by . This book was released on 1978 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Genetic Basis of Sleep and Sleep Disorders

Author : Paul Shaw
Publisher : Cambridge University Press
ISBN 13 : 1107435617
Total Pages : 434 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis The Genetic Basis of Sleep and Sleep Disorders by : Paul Shaw

Download or read book The Genetic Basis of Sleep and Sleep Disorders written by Paul Shaw and published by Cambridge University Press. This book was released on 2013-10-24 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive book on the subject, The Genetic Basis of Sleep and Sleep Disorders covers detailed reviews of the general principles of genetics and genetic techniques in the study of sleep and sleep disorders. The book contains sections on the genetics of circadian rhythms, of normal sleep and wake states and of sleep homeostasis. There are also sections discussing the role of genetics in the understanding of insomnias, hypersomnias including narcolepsy, parasomnias and sleep-related movement disorders. The final chapter highlights the use of gene therapy in sleep disorders. Written by genetic experts and sleep specialists from around the world, the book is up to date and geared specifically to the needs of both researchers and clinicians with an interest in sleep medicine. This book will be an invaluable resource for sleep specialists, neurologists, geneticists, psychiatrists and psychologists.

The HLA Complex in Biology and Medicine

Author : Narinder K Mehra
Publisher : Boydell & Brewer Ltd
ISBN 13 : 9788184488708
Total Pages : 616 pages
Book Rating : 4.4/5 (887 download)

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Book Synopsis The HLA Complex in Biology and Medicine by : Narinder K Mehra

Download or read book The HLA Complex in Biology and Medicine written by Narinder K Mehra and published by Boydell & Brewer Ltd. This book was released on 2010-11-26 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics.

HLA and Associated Important Diseases

Author : Yongzhi Xi
Publisher : BoD – Books on Demand
ISBN 13 : 9535112309
Total Pages : 386 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis HLA and Associated Important Diseases by : Yongzhi Xi

Download or read book HLA and Associated Important Diseases written by Yongzhi Xi and published by BoD – Books on Demand. This book was released on 2014-03-19 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This year marks the 60th anniversary of HLA discovery by the French Nobel laureate physician Jean Dausset, as well as the 55th anniversary of the identification and naming of the first HLA. Under such circumstances, both basic HLA research and its clinical applications need a new book that comprehensively reflects the latest achievements in the field. Thus, Professor Xi as Editor has contributed to organize international experts in the areas of HLA-related basic research and clinical applications, to unite their knowledge in chapters covering various related topics, and finally to finish the book "HLA and Associated Important Diseases". The book consists of three sections which mainly include basic theoretical and technological developments, several important HLA-associated autoimmune diseases and HLA-associated infectious diseases.

HLA and Disease

Author : William E. Braun
Publisher :
ISBN 13 :
Total Pages : 162 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis HLA and Disease by : William E. Braun

Download or read book HLA and Disease written by William E. Braun and published by . This book was released on 1979 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Evolution of the Major Histocompatibility Complex

Author : Jan Klein
Publisher : Springer Science & Business Media
ISBN 13 : 364284622X
Total Pages : 506 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Molecular Evolution of the Major Histocompatibility Complex by : Jan Klein

Download or read book Molecular Evolution of the Major Histocompatibility Complex written by Jan Klein and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: From molecules to populations and back In biology, the most vigorous organisms often ensue from a union of two disparate, pure lines. In science, too, laws of hybrid vigor seem to operate at the interface between two disciplines, an interface that often proves to be fertile ground for germinating concepts and new outlooks. The fringes of research into the major histocompatibility complex (Mhc) have provided such an interface several times in the past and the encounters have invigorated fields such as transplantation biology, cellular immunology, and immunogenetics. In the last few years, a new interface has been emerging between Mhc and evolutionary genetics, and particularly the branch of evolutionary genetics dealing with molecular evolution. Mhc research relies upon molecular evolutionary genetics, with its grand superstructure of mathematical formulations, to come to grips with the events leading to and maintaining the Mhc polymorphism. Without the armament of rigorous statistical procedures developed by evolutionary geneticists, the intricate relationships among Mhc genes cannot be resolved. It will undoubtedly be a molecular geneticist who is the final arbiter in the dispute concerning the nature of the selection pressure molding the Mhc genes. And it is doubtful whether the true function of Mhc can ever be comprehended without the vantage point afforded by the elucidation of its evolutionary history.

The association between HLA genes and autoimmune liver disease

Author : Yun Ma
Publisher : Frontiers Media SA
ISBN 13 : 2832520006
Total Pages : 127 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The association between HLA genes and autoimmune liver disease by : Yun Ma

Download or read book The association between HLA genes and autoimmune liver disease written by Yun Ma and published by Frontiers Media SA. This book was released on 2023-04-06 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt:

HLA from Benchtop to Bedside

Author : A. Bradley Eisenbrey
Publisher : Academic Press
ISBN 13 : 012824237X
Total Pages : 158 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis HLA from Benchtop to Bedside by : A. Bradley Eisenbrey

Download or read book HLA from Benchtop to Bedside written by A. Bradley Eisenbrey and published by Academic Press. This book was released on 2021-01-05 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: HLA from Benchtop to Bedside provides the reader with a comprehensive, concise and thoroughly up-to-date book on all aspects of the HLA system, including new techniques and methodologies. Each chapter begins with bullet point lists of principle learning points, including comprehensive references and validated links to international resources. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this book is ideal for organ and stem cell transplant professionals, histocompatibility laboratory professionals and staff, medical residents and fellows on transplant services, medical students, and students in clinical laboratory science. The book's author, Dr. Arthur Bradley Eisenbrey, is an experienced transplant pathologist who has held significant academic and leadership positions in the field. Reviews current knowledge surrounding the HLA system Covers current methodologies and utilization of histocompatibility testing Authored by a leader in the field of histocompatibility and transfusion medicine

The HLA System

Author : John Lee
Publisher : Springer Science & Business Media
ISBN 13 : 1461234549
Total Pages : 337 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis The HLA System by : John Lee

Download or read book The HLA System written by John Lee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume documents our growing understanding of the human major histocompatibility complex. The application of this information is ever more important as the limits of transplantation continue to be reduced, including the recent success of bone marrow transplantation between unrelated but closely matched individuals. In addition, the need to transfuse platelets in the face of immunologic barriers continues to challenge transfusion services. Thus, the serologic information summarized in this volume is essential for optimal patient care. At the same time, recombinant DNA technology has led to a revolution in our understanding of many aspects of basic biology. Among the advances has been the initial characterization of the structure of some HLA loci. While this will ultimately improve clinical services, constant reference to serologic data is essential so that the powerful new techniques can be applied in the most effective ways. The timing of the First Red Cross International Histocompatibility Workshop is fortunate as it brings together experts from around the world to address the state of the art. We are all grateful to Dr. John Lee and his colleagues for organizing the workshop, and for bringing together in this volume the material to be presented in Beijing during October 17-23, 1990. Leon W. Hoyer, M.D.

Autoimmune Liver Disease

Author : James Neuberger
Publisher : John Wiley & Sons
ISBN 13 : 1119532604
Total Pages : 336 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Autoimmune Liver Disease by : James Neuberger

Download or read book Autoimmune Liver Disease written by James Neuberger and published by John Wiley & Sons. This book was released on 2020-04-13 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to autoimmune liver diseases through pathogenesis, diagnosis, and management In Autoimmune Liver Disease Management and Clinical Practice, practitioners will learn about the current state of autoimmune liver disease and how to focus on their diagnosis and treatment. The four-part book begins with a thorough investigation of current immunological thinking as it relates to the autoimmunity of the liver. It also covers the four major hepatic autoimmune liver diseases in both adults and children, their management and the role of liver transplantation, and learned approaches to patient management and empowerment. Expert authors in the field have come together to provide a thorough examination of autoimmune liver disease to help support clinicians assisting patients. The text provides an in-depth look at topics including: ● The four major hepatic autoimmune liver diseases, their diagnosis, and potential disease management ● The use (and misuse) of autoantibodies in diagnosis and treatment ● The role and timing of liver transplantation and the impact of recurrent autoimmune liver disease as well as de novo autoimmune hepatitis ● Optimal approaches to managing patients and keeping care personalised With breadth, depth and current-day relevance, Autoimmune Liver Disease sheds light on recent developments in management of liver disease for practitioners, nurses, and health care professionals.