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Author : Kimiyoshi Tsuji
Publisher :
ISBN 13 :
Total Pages : 736 pages
Book Rating : 4.3/5 (91 download)
Download or read book HLA 1991 written by Kimiyoshi Tsuji and published by . This book was released on 1992 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jan Klein
Publisher : Springer Science & Business Media
ISBN 13 : 364284622X
Total Pages : 506 pages
Book Rating : 4.6/5 (428 download)
Download or read book Molecular Evolution of the Major Histocompatibility Complex written by Jan Klein and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: From molecules to populations and back In biology, the most vigorous organisms often ensue from a union of two disparate, pure lines. In science, too, laws of hybrid vigor seem to operate at the interface between two disciplines, an interface that often proves to be fertile ground for germinating concepts and new outlooks. The fringes of research into the major histocompatibility complex (Mhc) have provided such an interface several times in the past and the encounters have invigorated fields such as transplantation biology, cellular immunology, and immunogenetics. In the last few years, a new interface has been emerging between Mhc and evolutionary genetics, and particularly the branch of evolutionary genetics dealing with molecular evolution. Mhc research relies upon molecular evolutionary genetics, with its grand superstructure of mathematical formulations, to come to grips with the events leading to and maintaining the Mhc polymorphism. Without the armament of rigorous statistical procedures developed by evolutionary geneticists, the intricate relationships among Mhc genes cannot be resolved. It will undoubtedly be a molecular geneticist who is the final arbiter in the dispute concerning the nature of the selection pressure molding the Mhc genes. And it is doubtful whether the true function of Mhc can ever be comprehended without the vantage point afforded by the elucidation of its evolutionary history.
Author : Kam M. Hui
Publisher : CRC Press
ISBN 13 : 1000116840
Total Pages : 430 pages
Book Rating : 4.0/5 (1 download)
Download or read book Handbook of HLA Typing Techniques written by Kam M. Hui and published by CRC Press. This book was released on 2020-10-07 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an authoritative collection of HLA phenotyping and genotyping techniques to be used at the bench level and as a reference. It includes detailed methodologies, notes on the interpretation of tests, reference material, and appendices.
Author : Narinder K Mehra
Publisher : Boydell & Brewer Ltd
ISBN 13 : 9788184488708
Total Pages : 616 pages
Book Rating : 4.4/5 (887 download)
Download or read book The HLA Complex in Biology and Medicine written by Narinder K Mehra and published by Boydell & Brewer Ltd. This book was released on 2010-11-26 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics.
Author : Bjarte G. Solheim
Publisher : Springer Science & Business Media
ISBN 13 : 3642775063
Total Pages : 431 pages
Book Rating : 4.6/5 (427 download)
Download or read book The HLA System in Clinical Transplantation written by Bjarte G. Solheim and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: With this book we· want to address young graduate students, clini cians involved in transplantation, and technicians in transplantation immunology laboratories. The volume should give a comprehensive but basic, up to date introduction to the structure, function, and clinical importance of the HLA system. We believe that there is a need for such a survey, and think that the present level of our knowledge is an optimal occasion for publication. A significant number of ques tions have now been resolved, and our knowledge has reached a level of sophistication that provides the basis for additional questions and answers. Although the emphasis of this book is on the role of HLA anti gens in clinical transplantation, their involvement in other clinical contexts is also discussed. The main focus is on the human MHC an tigenic system, but MHC systems in other species are described as they contribute to our understanding of the structural and functional characteristics of HLA antigens. Some important issues related to laboratory techniques are also covered. The contributors have a close affiliation to the field of transplan tation immunology. A majority have even been playing important roles in unraveling the HLA system and its functions. We believe this has contributed significantly to the quality and clinical and practical relevance of the book. As editors, we drew up the principal guidelines and took care that the chapters can be read as separate entities, although this invariably results in some overlapping.
Author : John Lee
Publisher : Springer Science & Business Media
ISBN 13 : 1461234549
Total Pages : 337 pages
Book Rating : 4.4/5 (612 download)
Download or read book The HLA System written by John Lee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume documents our growing understanding of the human major histocompatibility complex. The application of this information is ever more important as the limits of transplantation continue to be reduced, including the recent success of bone marrow transplantation between unrelated but closely matched individuals. In addition, the need to transfuse platelets in the face of immunologic barriers continues to challenge transfusion services. Thus, the serologic information summarized in this volume is essential for optimal patient care. At the same time, recombinant DNA technology has led to a revolution in our understanding of many aspects of basic biology. Among the advances has been the initial characterization of the structure of some HLA loci. While this will ultimately improve clinical services, constant reference to serologic data is essential so that the powerful new techniques can be applied in the most effective ways. The timing of the First Red Cross International Histocompatibility Workshop is fortunate as it brings together experts from around the world to address the state of the art. We are all grateful to Dr. John Lee and his colleagues for organizing the workshop, and for bringing together in this volume the material to be presented in Beijing during October 17-23, 1990. Leon W. Hoyer, M.D.
Author : Kimiyoshi Tsuji
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (92 download)
Download or read book HLA 1991: and 2 written by Kimiyoshi Tsuji and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Steven G.E. Marsh
Publisher : Elsevier
ISBN 13 : 0080542506
Total Pages : 413 pages
Book Rating : 4.0/5 (85 download)
Download or read book The HLA FactsBook written by Steven G.E. Marsh and published by Elsevier. This book was released on 1999-12-13 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity. Introductory chapters provide good general overview of HLA field for novice immunologists and geneticists Up-to-date, complete listing of HLA alleles Invaluable reference resource for immunologists, geneticists, and cell biologists Combines both structural and functional information, which has never been compiled in a single reference book previously Serological specificity of allotypes Identity of material sequenced including ethnic origin Database accession numbers Population distribution Peptide binding specificities T cell epitopes Amino acid sequences of allotypes Key references
Author : J.L. Tiwari
Publisher : Springer Science & Business Media
ISBN 13 : 1461385458
Total Pages : 492 pages
Book Rating : 4.4/5 (613 download)
Download or read book HLA and Disease Associations written by J.L. Tiwari and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man. In the past, many genetic polymorphisms have been suspected to be associated with diseases. The most extensively studied markers are blood groups, enzymes, and serum proteins. A comprehensive account of published studies, totalling approximately 1,000, of these markers is available in a book by Mourant et al.
Author : Werner E. Braun
Publisher : CRC Press
ISBN 13 : 1351090127
Total Pages : 293 pages
Book Rating : 4.3/5 (51 download)
Download or read book HLA and Disease written by Werner E. Braun and published by CRC Press. This book was released on 2019-07-23 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the topic of the HLA antigen system. Chapters discuss topics such as; animal studies, the possible mechanisms of HLA and disease associations, statistical and genetic considerations, the clinical use of HLA typing, as well as the current status of HLA and disease associations.
Author : Kimiyoshi Tsuji
Publisher : Oxford University Press, USA
ISBN 13 : 9780192622174
Total Pages : 1992 pages
Book Rating : 4.6/5 (221 download)
Download or read book Hla 1991 written by Kimiyoshi Tsuji and published by Oxford University Press, USA. This book was released on 1993-02 with total page 1992 pages. Available in PDF, EPUB and Kindle. Book excerpt: * A must for all serious biomedical research libraries* The premier meeting for setting terminology and standardization in this area, based on a unique, collaborative experimental programme * Authoritative editors and a distinguished international cast of contributors This volume provides a comprehensive account of the HLA system, and draws together contributions from specialists in an extraordinarily wide range of biological, biomedical, and clinical specialities. The 1991 International Histocompatibility Workshop and Conference took place in Japan. The main business of the meeting is to consider the results from an enormous four year international collaborative testing programme, which used 537 selected sera and 32000 panel cells from 180 ethnic groups.From this programme, known HLA specificities are further analysed, subdivided, and their categorization refined and agreed. New HLA types are also identified. For the first time, the meeting used oligonucleotide probes and amplification techniques to provide an analysis of the system at the DNAlevel. All these results are reported in Part 1 and are not easily available elsewhere.Part 2 comprises the 199 conference papers, plenary lectures and special and mini-symposia. Many of the key areas are reviewed by leading authorities in immunogenetics, DNA analysis of the system, transplantation, disease susceptibility, immune regulation, T-cell biology, population genetics andevolution.
Author : Yongzhi Xi
Publisher : BoD – Books on Demand
ISBN 13 : 9535112309
Total Pages : 386 pages
Book Rating : 4.5/5 (351 download)
Download or read book HLA and Associated Important Diseases written by Yongzhi Xi and published by BoD – Books on Demand. This book was released on 2014-03-19 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This year marks the 60th anniversary of HLA discovery by the French Nobel laureate physician Jean Dausset, as well as the 55th anniversary of the identification and naming of the first HLA. Under such circumstances, both basic HLA research and its clinical applications need a new book that comprehensively reflects the latest achievements in the field. Thus, Professor Xi as Editor has contributed to organize international experts in the areas of HLA-related basic research and clinical applications, to unite their knowledge in chapters covering various related topics, and finally to finish the book "HLA and Associated Important Diseases". The book consists of three sections which mainly include basic theoretical and technological developments, several important HLA-associated autoimmune diseases and HLA-associated infectious diseases.
Author : Kam M. Hui
Publisher : CRC Press
ISBN 13 : 9780849305580
Total Pages : 438 pages
Book Rating : 4.3/5 (55 download)
Download or read book Handbook of HLA Typing Techniques written by Kam M. Hui and published by CRC Press. This book was released on 1993-07-15 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of HLA Typing Techniques is an authoritative collection of HLA phenotyping and genotyping techniques to be used at the bench level and as a reference. The information presented, much of it previously unpublished, was written by leading authorities in the field of transplantation. Each chapter provides detailed methodologies, notes on the interpretation of tests, reference material, and appendices. Phenotyping topics covered include microlymphocytotoxicity assay, monoclonal antibodies, complement testing, serum screening for HLA antibodies, lymphocytotoxic crossmatching, and mixed and primed lymphocyte testing. Genotyping topics discussed include well-established RFLP analysis and polymerase chain reaction applications of PCR-SSO, PCR-RFLP, PCR-SSP, and PCR fingerprinting and related DNA heteroduplex technologies. Handbook of HLA Typing Techniques is an indispensable sourcebook for all researchers, practitioners, and students in the international tissue typing and human immunogenetics community.
Author : Batool Mutar Mahdi
Publisher : BoD – Books on Demand
ISBN 13 : 1789857619
Total Pages : 70 pages
Book Rating : 4.7/5 (898 download)
Download or read book Human Leukocyte Antigen (HLA) written by Batool Mutar Mahdi and published by BoD – Books on Demand. This book was released on 2019-03-13 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a concise review of medically important applications of Human Leukocyte Antigen (HLA) in medicine. It covers both basic knowledge of HLA and its main clinical applications in medical practice. Its two major aims are to assist students who are preparing for clinical immunology examinations, and to help people who want to understand more about this subject with brief and flexible sources of information. This book presents current, medically important information on the rapidly changing field of tissue typing and its relation with diseases. It includes updated information on such topics as tissue typing in medicine and transplant immunology.
Author : Kimiyoshi Tsuji
Publisher :
ISBN 13 : 9780192623898
Total Pages : pages
Book Rating : 4.6/5 (238 download)
Download or read book HLA 1991 written by Kimiyoshi Tsuji and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Arne Svejgaard
Publisher :
ISBN 13 :
Total Pages : 124 pages
Book Rating : 4.3/5 (91 download)
Download or read book The HLA System written by Arne Svejgaard and published by . This book was released on 1979 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert Lechler
Publisher : Academic Press
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.3/5 (91 download)
Download or read book HLA in Health and Disease written by Robert Lechler and published by Academic Press. This book was released on 2000-05-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and definitive work succeeds and expands on the highly successful HLA and Disease published in 1994. This new edition has been updated, redesigned and reorganised into three sections making it an invaluable reference. The introductory section summarises current knowledge on the structure, function, genetics and evolution of the HLA system. It clarifies its complex and ever changing nomenclature and discusses the mechanisms underlying disease associations with HLA alleles. The second section deals with the importance of HLA in the context of different clinical specialities. Individual chapters describe the association between HLA polymorphism and each disease. The final section features chapters on current laboratory practice in histocompatibility and tissue typing. HLA in Health and Disease is essential reading for basic and clinical researchers working in immunology and immunogenetics, transplantation medicine and autoimmunity. It will also be of interest to anyone in the fields of rheumatology, diabetology, nephrology, allergy, dermatology, neurology, endocrinology, cancer biology, respiratory medicine, haematology, molecular biology and biochemistry. Key Features Structure, function and genetics of HLA HLA nomenclature Evolution of HLA polymorphisms HLA associations in arthritis and rheumatology, renal disease, neurology, diabetes and endocrinology, gastroenterology, respiratory disease, ophthalmology, infections, dermatology and psychiatry HLA and organ transplantation Serological and PCR-based methods in HLA typing Cellular techniques in testing histocompatibility Edited and written by an international panel of experts in the field
