Hiv Molecular Organization Pathogenicity And Treatment

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HIV Molecular Organization, Pathogenicity and Treatment

Author : John Morrow
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis HIV Molecular Organization, Pathogenicity and Treatment by : John Morrow

Download or read book HIV Molecular Organization, Pathogenicity and Treatment written by John Morrow and published by Elsevier Science & Technology. This book was released on 1993 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now 12 years since the first reports of AIDS, and the disease has become a pandemic of devastating proportions. Despite the enormous social, emotional and economic costs, some rays of hope are now visible. Biomedical research into the problems presented by the disease has gained considerable momentum. The discovery of the etiologic agent, the human immunodeficiency virus (HIV), in the mid-1980's has resulted in massive efforts to characterize the organism. In addition the development of new therapies is under intense study and anti-viral and immunomodulating drugs are showing some efficiency in preliminary testing. To date, attempts to produce a protective vaccine have been only partially successful, but these investigations are continuing unabated and we can remain cautiously optimistic that these tremendous efforts may yield some promise in the medium, if not short-term, period. In compiling this volume, the authors have aimed to review key topics in the fast-moving field of HIV research and provide the reader with easy access to current literature and trends in experimentation.

HIV and the New Viruses

Author : Angus G. Dalgleish
Publisher : Academic Press
ISBN 13 :
Total Pages : 620 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis HIV and the New Viruses by : Angus G. Dalgleish

Download or read book HIV and the New Viruses written by Angus G. Dalgleish and published by Academic Press. This book was released on 1999 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV and the New Viruses presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time. These cover recently discovered viruses such as HHV-6, HHV-8 and HCV, as well as the latest research on HIV. This comprehensive and updated reference includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses and management of conditions associated with those viruses. Information on new pharmaceuticals and vaccine developments is also included. Edited by the leading experts in the field, HIV and the New Viruses will be essential reading for postgraduates, clinicians and researchers in virology, immunology, cancer, molecular biology and the pharmaceutical industry. Presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time Includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses, and management of conditions associated with those viruses

HIV I: Molecular Biology and Pathogenesis: Clinical Applications

Author :
Publisher : Academic Press
ISBN 13 : 0080549861
Total Pages : 561 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis HIV I: Molecular Biology and Pathogenesis: Clinical Applications by :

Download or read book HIV I: Molecular Biology and Pathogenesis: Clinical Applications written by and published by Academic Press. This book was released on 2000-09-26 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines. The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia. Detailed insights into viral packaging, expression, and assembly Mechanistic understanding of how HIV interacts with receptors and infects cells Delineation of virally encoded regulatory processes unique to HIV Clinical Applications: An updated review of current chemotherapeutics for HIV New concepts in the discovery and design of novel anti-HIV drugs The latest developments in HIV-vaccine research

Nutrition and HIV

Author : Saurabh Mehta
Publisher : CRC Press
ISBN 13 : 1351058185
Total Pages : 326 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Nutrition and HIV by : Saurabh Mehta

Download or read book Nutrition and HIV written by Saurabh Mehta and published by CRC Press. This book was released on 2018-05-15 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world continues to lose more than a million lives each year to the HIV epidemic, and nearly two million individuals were infected with HIV in 2017 alone. The new Sustainable Development Goals, adopted by countries of the United Nations in September 2015, include a commitment to end the AIDS epidemic by 2030. Considerable emphasis on prevention of new infections and treatment of those living with HIV will be needed to make this goal achievable. With nearly 37 million people now living with HIV, it is a communicable disease that behaves like a noncommunicable disease. Nutritional management is integral to comprehensive HIV care and treatment. Improved nutritional status and weight gain can increase recovery and strength of individuals living with HIV/AIDS, improve dietary diversity and caloric intake, and improve quality of life. This book highlights evidence-based research linking nutrition and HIV and identifies research gaps to inform the development of guidelines and policies for the United Nations’ Sustainable Development Goals. A comprehensive approach that includes nutritional interventions is likely to maximize the benefit of antiretroviral therapy in preventing HIV disease progression and other adverse outcomes in HIV-infected men and women. Modification of nutritional status has been shown to enhance the quality of life of those suffering HIV/AIDS, both physically in terms of improved body mass index and immunological markers, and psychologically, by improving symptoms of depression. While the primary focus for those infected should remain on antiretroviral treatment and increasing its availability and coverage, improvement of nutritional status plays a complementary role in the management of HIV infection.

AIDS Bibliography

Author :
Publisher :
ISBN 13 :
Total Pages : 184 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis AIDS Bibliography by :

Download or read book AIDS Bibliography written by and published by . This book was released on 1995-06 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomaterials for Clinical Applications

Author : Sujata K. Bhatia
Publisher : Springer Science & Business Media
ISBN 13 : 1441969209
Total Pages : 286 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Biomaterials for Clinical Applications by : Sujata K. Bhatia

Download or read book Biomaterials for Clinical Applications written by Sujata K. Bhatia and published by Springer Science & Business Media. This book was released on 2010-10-14 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for Clinical Applications is organized according to the World Health Organization’s report of the top 11 causes of death worldwide, and lays out opportunities for both biomaterials scientists and physicians to tackle each of these leading contributors to mortality. The introductory chapter discusses the global burden of disease. Each of the subsequent eleven chapters focuses on a specific disease process, beginning with the leading cause of death worldwide, cardiovascular disease. The chapters start with describing diseases where clinical needs are most pressing, and then envisions how biomaterials can be designed to address these needs, instead of the more technologically centered approached favored by most books in the field. This book, then, should appeal to chemical engineers and bioengineers who are designing new biomaterials for drug delivery and vaccine delivery, as well as tissue engineering.

Retroviruses

Author : Reinhard Kurth
Publisher :
ISBN 13 : 9781912530977
Total Pages : pages
Book Rating : 4.5/5 (39 download)

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Book Synopsis Retroviruses by : Reinhard Kurth

Download or read book Retroviruses written by Reinhard Kurth and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook on Immunosenescence

Author : Tamas Fulop
Publisher : Springer Science & Business Media
ISBN 13 : 1402090633
Total Pages : 1693 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook on Immunosenescence by : Tamas Fulop

Download or read book Handbook on Immunosenescence written by Tamas Fulop and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Fundamentals of HIV Medicine

Author : William David Hardy
Publisher : Oxford University Press
ISBN 13 : 0190493097
Total Pages : 617 pages
Book Rating : 4.1/5 (94 download)

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Book Synopsis Fundamentals of HIV Medicine by : William David Hardy

Download or read book Fundamentals of HIV Medicine written by William David Hardy and published by Oxford University Press. This book was released on 2017-04-18 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely updated for 2017, Fundamentals of HIV Medicine is a comprehensive clinical care publication for the treatment of HIV/AIDS. Published by the American Academy of HIV Medicine, the book offers physicians, pharmacists, nurse practitioners, and other care providers the most up-to-date overview of the latest HIV treatments and guidelines plus online access to CME. The online access expires August 2018. Embodying the AAHIVM's commitment to promoting uniform excellence in care of seropositive patients, Fundamentals of HIV Medicine 2017 empowers health professionals to deliver standardized, life-sustaining treatment to the patients who need it most. It will serve as an essential clinical reference and provide valuable career enrichment to users across the spectrum of HIV care, treatment, and prevention.

The Retroviridae

Author : Jay A. Levy
Publisher : Springer Science & Business Media
ISBN 13 : 1489917217
Total Pages : 684 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis The Retroviridae by : Jay A. Levy

Download or read book The Retroviridae written by Jay A. Levy and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: depth overview of the retrovirus family. I have greatly enjoyed and learned from this experience. Each chapter is an excellent introduction to the topic covered and provides a good foundation for further work in the field. Jay A. Levy University of California School of Medicine San Francisco, California REFERENCES Brown, E. W., Yuhki, N., Packer, C., and O'Brien, S. J., 1994, A lion lentivirus related to feline immunodeficiency virus: Epidemiologic and phylogenetic aspects, ,. Viral. 68:5953-5968. Merza, M., Larsson, E., Steen, M., and Morein, B., 1994, Association of a retrovirus with a wasting condition in the Swedish moose, Virology 202:956-961. Contents Chapter 1 The Human Immunodeficiency Viruses Edward Barker, Susan W Barnett, Leonidas Stamatatos, and Jay A. Levy I. Introduction .................................................... 1 TI. Description of Agent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 A. Virus Structure .............................................. 2 B. Genetic Organization and Gene Function ...................... 2 TIL Transmission.................................................... 7 A. General Observations ........................................ 7 B. HIV Transmission by Blood and Blood Products ................ 8 C. HIV Transmission by Genital Fluids ........................... 10 D. HIV Transmission by Other Body Fluids ....................... 12 E. Mother-to-Child Transmission ................................ 12 IV. HIV Infection of the Cell . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 . . . . . . . . . . . . . A. Introduction ................................................. 13 B. HIV-Cell Interaction............ ............... .............. 15 C. CD4-Induced gp120 Conformational Changes .................. 16 D. Soluble CD4-Induced gp120-gp41 Dissociation..... ............ 16 E. gp120 Proteolytic Cleavage ................................... 17 F. pH-Independent Membrane Fusion ............................ 19 G. Transmission of HIV by Cell-to-Cell Fusion.................... 19 H. Additional Cell Surface Receptors for HIV ..................... 20 I. The Envelope Region and Cell Tropism ........ . . . . . . . . . . . . 21 . . . .

Biological Aspects of Disease

Author : Philip M. Iannaccone
Publisher : CRC Press
ISBN 13 : 9783718606139
Total Pages : 408 pages
Book Rating : 4.6/5 (61 download)

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Book Synopsis Biological Aspects of Disease by : Philip M. Iannaccone

Download or read book Biological Aspects of Disease written by Philip M. Iannaccone and published by CRC Press. This book was released on 1997-06-23 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains eleven contributions which address specific examples of the way in which animal experimentation leads to data applicable to human disease. Includes coverage of the ethics of animal use and advantages of animal models over alternate systems, including computer simulation, tissue culture, and in vitro biochemistry. Annotation copyrighted by Book News, Inc., Portland, OR

Advances in Cancer Research

Author : George F. Vande Woude
Publisher : Gulf Professional Publishing
ISBN 13 : 9780120066872
Total Pages : 282 pages
Book Rating : 4.0/5 (668 download)

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Book Synopsis Advances in Cancer Research by : George F. Vande Woude

Download or read book Advances in Cancer Research written by George F. Vande Woude and published by Gulf Professional Publishing. This book was released on 2003-03-05 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics, including chromosome instability in cancer; telomerase inhibitors as an option for chemotherapy; avian retrovirus pathogenicity; Epstein-Barr virus and undifferentiated nasopharyngeal carcinoma; immunotherapy for prostate cancer; and the role of lymphocytes in anti-tumor immunity. Provides invaluable information on the exciting and fast-moving field of cancer research. Presents outstanding and original reviews on a variety of topics, including chromosome instability in cancer; telomerase inhibitors as an option for chemotherapy; avian retrovirus pathogenicity; Epstein-Barr virus and undifferentiated nasopharyngeal carcinoma; immunotherapy for prostate cancer; and the role of lymphocytes in anti-tumor immunity

Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection

Author : World Health Organization
Publisher :
ISBN 13 : 9789241549684
Total Pages : 429 pages
Book Rating : 4.5/5 (496 download)

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Book Synopsis Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection by : World Health Organization

Download or read book Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection written by World Health Organization and published by . This book was released on 2016 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral drugs following an extensive review of evidence and consultations in mid-2015, shared at the end of 2015, and now published in full in 2016. It is being published in a changing global context for HIV and for health more broadly.

Drug Discovery Strategies and Methods

Author : Alexandros Makriyannis
Publisher : CRC Press
ISBN 13 : 9780203913277
Total Pages : 378 pages
Book Rating : 4.9/5 (132 download)

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Book Synopsis Drug Discovery Strategies and Methods by : Alexandros Makriyannis

Download or read book Drug Discovery Strategies and Methods written by Alexandros Makriyannis and published by CRC Press. This book was released on 2003-11-04 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Navigate the complex and multidisciplinary path of drug discovery procedures with Drug Discovery Strategies and Methods-a well-organized and timely reference that analyzes methods in target identification and validation, lead detection, compound optimization, and biological testing. This volume addresses challenges encountered during the discovery

AIDS Pathogenesis

Author : H. Schuitemaker
Publisher : Springer Science & Business Media
ISBN 13 : 9780792361961
Total Pages : 300 pages
Book Rating : 4.3/5 (619 download)

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Book Synopsis AIDS Pathogenesis by : H. Schuitemaker

Download or read book AIDS Pathogenesis written by H. Schuitemaker and published by Springer Science & Business Media. This book was released on 2000-03-31 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

Nathan and Oski's Hematology and Oncology of Infancy and Childhood

Author : Stuart H. Orkin
Publisher : Elsevier Health Sciences
ISBN 13 : 0323291775
Total Pages : 3517 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Nathan and Oski's Hematology and Oncology of Infancy and Childhood by : Stuart H. Orkin

Download or read book Nathan and Oski's Hematology and Oncology of Infancy and Childhood written by Stuart H. Orkin and published by Elsevier Health Sciences. This book was released on 2014-11-14 with total page 3517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the leading names in pediatric oncology and hematology, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski’s is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.

Viral Molecular Machines

Author : Michael G. Rossmann
Publisher : Springer Science & Business Media
ISBN 13 : 1461409802
Total Pages : 685 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Viral Molecular Machines by : Michael G. Rossmann

Download or read book Viral Molecular Machines written by Michael G. Rossmann and published by Springer Science & Business Media. This book was released on 2012-02-02 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, synthesis and assembly of viral structural components, genome packaging and maturation into an infectious virion. Each chapter will describe the components of the respective machine in molecular or atomic detail, genetic and biochemical analyses, and mechanism. Topics are carefully selected so that the reader is exposed to systems where there is a substantial infusion of new knowledge in recent years, which greatly elevated the fundamental mechanistic understanding of the respective molecular machine. The authors will be encouraged to simplify the detailed knowledge to basic concepts, include provocative new ideas, as well as design colorful graphics, thus making the cutting-edge information accessible to broad audience.