Hereditary Breast and Ovarian Cancer

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Author :
Publisher : Springer Nature
ISBN 13 : 9811645213
Total Pages : 324 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Hereditary Breast and Ovarian Cancer by : Seigo Nakamura

Download or read book Hereditary Breast and Ovarian Cancer written by Seigo Nakamura and published by Springer Nature. This book was released on 2021-10-20 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.

Confronting Hereditary Breast and Ovarian Cancer

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Author :
Publisher : JHU Press
ISBN 13 : 1421404451
Total Pages : 320 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Confronting Hereditary Breast and Ovarian Cancer by : Sue Friedman

Download or read book Confronting Hereditary Breast and Ovarian Cancer written by Sue Friedman and published by JHU Press. This book was released on 2012-03-01 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Be informed. Be empowered. Be well." If you are concerned that the cancer in your family is hereditary, you face difficult choices. Should you have a blood test that may reveal whether you have a high likelihood of disease? Do you preemptively treat a disease that may never develop? How do you make decisions now that will affect the rest of your life? This helpful, informative guide answers your questions as you confront hereditary breast and ovarian cancer. Developed by Facing Our Risk of Cancer Empowered (FORCE), the nation’s only nonprofit organization dedicated to supporting families affected by hereditary breast and ovarian cancer, this book stands alone among breast and ovarian cancer resources. Equal parts health guide and memoir, it defines complex issues facing previvors and survivors and provides solutions with a fresh, authoritative voice. Written by three passionate advocates for the hereditary cancer community who are themselves breast cancer survivors, Confronting Hereditary Breast and Ovarian Cancer dispels myths and misinformation and presents practical risk-reducing alternatives and decision-making tools. Including information about genetic counseling and testing, preventive surgery, and fertility and family planning, as well as explanations of health insurance coverage and laws protecting genetic privacy, this resource tackles head-on the challenges of living in a high-risk body. Confronting hereditary cancer is a complex, confusing, and highly individual journey. With its unique combination of the latest research, expert advice, and compelling personal stories, this book gives previvors, survivors, and their family members the guidance they need to face the unique challenges of hereditary cancer.

Gynaecology by Ten Teachers

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Author :
Publisher : CRC Press
ISBN 13 : 1498744435
Total Pages : 541 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Gynaecology by Ten Teachers by : Louise C Kenny

Download or read book Gynaecology by Ten Teachers written by Louise C Kenny and published by CRC Press. This book was released on 2017-05-08 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1919 as 'Diseases of Women', Gynaecology by Ten Teachers is well established as a concise, yet comprehensive, guide. The twentieth edition has been thoroughly updated by a new team of 'teachers', integrating clinical material with the latest scientific developments that underpin patient care. Each chapter is highly structured, with learning objectives, definitions, aetiology, clinical features, investigations, treatments, case histories and key point summaries and additional reading where appropriate. New themes for this edition include 'professionalism' and 'global health' and information specific to both areas is threaded throughout the text.

Positive Results

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Publisher : Prometheus Books
ISBN 13 : 1615927735
Total Pages : 397 pages
Book Rating : 4.6/5 (159 download)

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Book Synopsis Positive Results by : Joi L. Morris

Download or read book Positive Results written by Joi L. Morris and published by Prometheus Books. This book was released on 2010-06-03 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique and important guidebook is a single, comprehensive source of information and advice to help women (and some men) at high risk for breast and for ovarian cancer because of family history and genetic profile. One part memoir, three parts "how to" manual, Positive Results explains in a clear and steady manner the myths and realities of "the breast cancer genes." It lays out all the options in easy-to-follow, compassionate language. It will help women and men decide if they want to pursue genetic testing, guide them in interpreting their test results, and give them a sound basis for making the life-saving decisions required to manage their risks. Authors Joi Morris and Dr. Ora Karp Gordon cover all of the latest medical options, including genetic testing for breast cancer risk, breast cancer surveillance, assessing risk, mastectomy and breast reconstruction techniques, ovarian cancer surveillance, surgery, managing menopause, and cancer risks in men who carry mutations on BRCA genes. Along the way, Joi tells her personal story and that of other women and men who have made the gut-wrenching decisions required to survive in this world of astronomical risk. At the age of forty-two, Joi learned that she has a genetic mutation on a gene known as BRCA2. The test results meant that her risk of getting breast cancer could be as high as 84 percent by age seventy, and that her risk for ovarian cancer was also high. Compounding her risk was the fact that her mother had developed breast cancer in her forties. After much research and consultation, the result of which is this book, Joi made the difficult decision of undergoing prophylactic mastectomies. This straightforward and practical approach combined with the poignant personal experience of a woman at risk facing these challenging decisions will provide readers with the feeling that they have had the benefit of a long conversation with both a trusted physician and a friend who has just gone through the same uncertainties they are facing.

Probably Someday Cancer

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Author :
Publisher : University of North Texas Press
ISBN 13 : 1574417576
Total Pages : 209 pages
Book Rating : 4.5/5 (744 download)

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Book Synopsis Probably Someday Cancer by : Kim Horner

Download or read book Probably Someday Cancer written by Kim Horner and published by University of North Texas Press. This book was released on 2019-02-15 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: After learning that she inherited a BRCA2 genetic mutation that put her at high risk for breast and ovarian cancer, Kim Horner’s doctors urged her to consider having a double mastectomy. But how do you decide whether to have a surgery to remove your breasts to reduce your risk for a disease you don’t have and may never get? Horner shares her struggle to answer that question in Probably Someday Cancer. The mother of a one-year-old boy, she wanted to do whatever would give her the best odds of being around for her son and protect her from breast cancer, which killed her grandmother and great-grandmother in their 40s. Which would give her the best chance at a long healthy life: a double mastectomy or frequent screenings to try to catch any cancer early? The answers weren’t that simple. Based on extensive research, interviews, and personal experience, Horner writes about how and why she ultimately opted for a double mastectomy—the same decision actress Angelina Jolie made for a similar genetic mutation—and the surprising diagnosis that followed. The book explores difficult truths that get overshadowed by upbeat messages about early detection and survivorship—the fact that screenings can miss cancers and that even early-stage breast cancers can spread and become fatal. Probably Someday Cancer is about the author’s efforts to push past her fear and anxiety. This book can help anyone facing hereditary risk of breast and ovarian cancer feel less alone and make informed decisions to protect their health and end the devastation that hereditary cancer has caused for generations in so many families.

The Genetics of Cancer

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401106770
Total Pages : 222 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis The Genetics of Cancer by : B.A. Ponder

Download or read book The Genetics of Cancer written by B.A. Ponder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Waiting for Cancer to Come

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Author :
Publisher : University of Michigan Press
ISBN 13 : 0472052195
Total Pages : 227 pages
Book Rating : 4.4/5 (72 download)

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Book Synopsis Waiting for Cancer to Come by : Sharlene Hesse-Biber

Download or read book Waiting for Cancer to Come written by Sharlene Hesse-Biber and published by University of Michigan Press. This book was released on 2014-07-28 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: A narrative-driven exploration of the effects of BRCA genetic testing on the lives of at-risk women

Ovarian and Fallopian Tube Cancer

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Author :
Publisher : Wiley-Blackwell
ISBN 13 : 9780632044320
Total Pages : 112 pages
Book Rating : 4.0/5 (443 download)

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Book Synopsis Ovarian and Fallopian Tube Cancer by : John Kavanagh

Download or read book Ovarian and Fallopian Tube Cancer written by John Kavanagh and published by Wiley-Blackwell. This book was released on 1998-11-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book derived from the section of the same name from Cancer in Women, represents a concise overview of the current approaches to the diagnosis and management of ovarian cancer. Therapeutic chapters cover surgery and reconstruction, radiotherpay and adjuvant therapy.

Cancer and the Environment

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Author :
Publisher : National Academies Press
ISBN 13 : 0309169240
Total Pages : 160 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cancer and the Environment by : Institute of Medicine

Download or read book Cancer and the Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2002-08-01 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Roundtable on Environmental Health Sciences, Research, and Medicine wanted to address the link between environmental factors and the development of cancer in light of recent advances in genomics. They asked what research tools are needed, how new scientific information can be applied in a timely manner to reduce the burden of cancer, and how this can be flexible enough to treat the individual.

Diagnosis and Management of Ovarian Disorders

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Author :
Publisher : Elsevier
ISBN 13 : 008049451X
Total Pages : 595 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek

Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine

Clinical Gynecology

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1107040396
Total Pages : 1127 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Gynecology by : Eric J. Bieber

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

A Cancer in the Family

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Author :
Publisher : Penguin
ISBN 13 : 0698197895
Total Pages : 306 pages
Book Rating : 4.6/5 (981 download)

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Book Synopsis A Cancer in the Family by : Theodora Ross, MD, PhD

Download or read book A Cancer in the Family written by Theodora Ross, MD, PhD and published by Penguin. This book was released on 2016-02-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Kirkus Best Book of 2016 Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States, and it’s estimated that about 1.3 million of these cases are hereditary. Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work. Using her own family’s story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers readers to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.

Saving Women's Lives

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Author :
Publisher : National Academies Press
ISBN 13 : 0309165946
Total Pages : 384 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Saving Women's Lives by : National Research Council

Download or read book Saving Women's Lives written by National Research Council and published by National Academies Press. This book was released on 2005-03-18 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The outlook for women with breast cancer has improved in recent years. Due to the combination of improved treatments and the benefits of mammography screening, breast cancer mortality has decreased steadily since 1989. Yet breast cancer remains a major problem, second only to lung cancer as a leading cause of death from cancer for women. To date, no means to prevent breast cancer has been discovered and experience has shown that treatments are most effective when a cancer is detected early, before it has spread to other tissues. These two facts suggest that the most effective way to continue reducing the death toll from breast cancer is improved early detection and diagnosis. Building on the 2001 report Mammography and Beyond, this new book not only examines ways to improve implementation and use of new and current breast cancer detection technologies but also evaluates the need to develop tools that identify women who would benefit most from early detection screening. Saving Women's Lives: Strategies for Improving Breast Cancer Detection and Diagnosis encourages more research that integrates the development, validation, and analysis of the types of technologies in clinical practice that promote improved risk identification techniques. In this way, methods and technologies that improve detection and diagnosis can be more effectively developed and implemented.

Cancer Susceptibility

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Author :
Publisher : Humana Press
ISBN 13 : 9781607617587
Total Pages : 0 pages
Book Rating : 4.6/5 (175 download)

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Book Synopsis Cancer Susceptibility by : Michelle Webb

Download or read book Cancer Susceptibility written by Michelle Webb and published by Humana Press. This book was released on 2010-09-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past two decades, spectacular advances have been made in our understanding of the molecular genetics of cancer, leading to the pursuit of identifying genes that, when mutated, result in an increased susceptibility to the disease. In Cancer Susceptibility: Methods and Protocols, experts in the field bring together the most recent technological developments for identifying and screening cancer susceptibility genes. Divided into two clear sections, the book begins with gene identification, which updates and informs scientists working at identifying novel cancer susceptibility genes, while the second part deals with mutation screening technologies that aid scientists and clinicians working to translate this knowledge into the clinic. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Susceptibility: Methods and Protocols is a timely collection that seeks to provide researchers with the tools to predict and combat this terrible disease.

Concise Handbook of Familial Cancer Susceptibility Syndromes

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Author :
Publisher :
ISBN 13 : 9780199558391
Total Pages : 93 pages
Book Rating : 4.5/5 (583 download)

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Book Synopsis Concise Handbook of Familial Cancer Susceptibility Syndromes by :

Download or read book Concise Handbook of Familial Cancer Susceptibility Syndromes written by and published by . This book was released on 2008 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genes and Cancer

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Author :
Publisher : Wiley
ISBN 13 : 9780471925835
Total Pages : 364 pages
Book Rating : 4.9/5 (258 download)

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Book Synopsis Genes and Cancer by : Karol Sikora

Download or read book Genes and Cancer written by Karol Sikora and published by Wiley. This book was released on 1990-10-26 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work serves as an introduction to the applications of molecular biology in the field of oncology. It provides a basic understanding of the genetic events involved in fully developed human cancer, including research into inherited and acquired gene defects initiating new neoplasms and the subsequent genetic alterations involved in tumor progression. Some of the specific topics explored include gene control, molecular therapy and antibodies, drug resistance, growth factors and receptors, and tumor biology. While intended primarily as an advanced text for oncologists, postgraduate molecular geneticists and molecular biologists, the book will certainly be of interest to other researchers who frequently encounter cancer in their practice.

Clinical Cancer Genetics

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Author :
Publisher : Wiley-Blackwell
ISBN 13 : 9780471458937
Total Pages : 452 pages
Book Rating : 4.4/5 (589 download)

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Book Synopsis Clinical Cancer Genetics by : Kenneth Offit

Download or read book Clinical Cancer Genetics written by Kenneth Offit and published by Wiley-Blackwell. This book was released on 2030-05-07 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a world-recognized leader in this emerging field, Clinical Cancer Genetics provides an updated and expanded treatment of Kenneth Offit's seminal text on the clinical management associated with syndromes of cancer predisposition, with a thorough review of the relevant molecular genetics. This second edition features new coverage of pharmacogenetics, gene therapy trials, high throughput genotyping, and microarrays and includes a new focus on epigenetic events in carcinogenesis within background chapter on cancer genetics. Expanded coverage highlights more uncommon and rare cancer predisposition syndromes.