Mammalian Toxicology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119940419
Total Pages : 716 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Mammalian Toxicology by : Mohamed Abou-Donia

Download or read book Mammalian Toxicology written by Mohamed Abou-Donia and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian Toxicology surveys chemical agents and examines how such chemicals impact on human health, emphasizing the importance in minimizing environmental exposure to chemical and physical hazards in our homes, communities and workplaces through such media as contaminated water, soil and air. Starting with the basic principles on a wide range of toxic agents, this textbook describes how they enter the body, their mechanisms of action once inside, and strategies for diagnosis, prevention and treatment. Topics covered include: General principles of toxicology: pharmacological and toxicological principles underpinning the study of toxicology, risk assessments and mechanisms of cell death Disposition: routes of chemical exposures, entry into the body and various tissues, storage, metabolic biotransformation and elimination, with examples from various toxicants. Toxic agents: the occurrences, disposition in the body, health effects, toxic mechanisms, antidotes and treatments of a range of agents including pesticides, metals, solvents, gases, nanomaterials, food components and additives, pharmaceuticals, drugs of abuse, natural toxins, endocrine disruptors, radiation, and warfare weapons. Toxic effects: including neurotoxicity, developmental toxicity, immunotoxicity, teratogenecity, male and female reproductive toxicity, mutagenecity, carcinogenicity, pulmonary toxicity, cardiovascular toxicity, hepatotoxicity, gastrointestinal toxicity and cardiovascular toxicity Toxicology and society: epidemiological studies of chemical-induced diseases in human populations, and a vision for toxicology in the 21st century. Mammalian Toxicology is an essential primer for students of toxicology, biochemistry, biology, medicine and chemistry. It is also appropriate for professional toxicologists in research or regulatory affairs, and anyone who needs to understand the adverse effects of toxic agents on the human body.

Toxicological Profile for Perfluoroalkyls

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Author :
Publisher :
ISBN 13 :
Total Pages : 412 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis Toxicological Profile for Perfluoroalkyls by :

Download or read book Toxicological Profile for Perfluoroalkyls written by and published by . This book was released on 2009 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This toxicological profile for perfluoroalkyls was prepared consistent with guidelines developed by the Agency for Toxic Substances and Disease Registry (ATSDR) and the Environmental Protection Agency (EPA) for the preparation of toxicological profiles. The original guidelines were published in the Federal Register on April 17, 1987. While Perfluoroalkyls are not found on the ATSDR list of Priority Hazardous Substances, ATSDR has determined that a profile for these substances was necessary because data indicate that some perfluoroalkyls are found in the blood of the U.S. general population and in the environment. The agency also determined that it was important to characterize the current available information regarding the health effects from exposure in order to support and inform public health responses and activities by ATSDR and other." -- p. v

Effects of Disease on Clinical Laboratory Tests

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Publisher : Columbia University Press
ISBN 13 : 9780915274529
Total Pages : 1310 pages
Book Rating : 4.2/5 (745 download)

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Book Synopsis Effects of Disease on Clinical Laboratory Tests by : Richard B. Friedman

Download or read book Effects of Disease on Clinical Laboratory Tests written by Richard B. Friedman and published by Columbia University Press. This book was released on 1989 with total page 1310 pages. Available in PDF, EPUB and Kindle. Book excerpt: An aid to determine the possible cause of laboratory test abnormalities encountered in clinical practice. Sections include laboratory test index, disease keyword index, laboratory test listings, disease listings by ICD-9CM classification, and references.

Ecological Impacts of Toxic Chemicals

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Author :
Publisher : Francisco Sanchez-Bayo
ISBN 13 : 1608051218
Total Pages : 288 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Ecological Impacts of Toxic Chemicals by : Francisco Sánchez-Bayo, Paul J. van den Brink, Reinier M. Mann

Download or read book Ecological Impacts of Toxic Chemicals written by Francisco Sánchez-Bayo, Paul J. van den Brink, Reinier M. Mann and published by Francisco Sanchez-Bayo. This book was released on 2011-09-09 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecological Impacts of Toxic Chemicals presents a comprehensive, yet readable account of the known disturbances caused by all kinds of toxic chemicals on both aquatic and terrestrial ecosystems. Topics cover the sources of toxicants, their fate and distribution through the planet, their impacts on specific ecosystems, and their remediation by natural systems. Each chapter is written by well-known specialists in those areas, for the general public, students, and even scientists from outside this field. The book intends to raise awareness of the dangers of chemical pollution in a world dominated by industry and globalization of resources. Because the problems are widespread and far reaching, it is hoped that confronting the facts may prompt better management practices at industrial, agricultural and all levels of management, from local to governmental, so as to reduce the negative impacts of chemical contaminants on our planet.

Biodegradation of Toxic and Hazardous Chemicals

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Author :
Publisher : CRC Press
ISBN 13 : 1040004180
Total Pages : 205 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Biodegradation of Toxic and Hazardous Chemicals by : Kashyap K. Dubey

Download or read book Biodegradation of Toxic and Hazardous Chemicals written by Kashyap K. Dubey and published by CRC Press. This book was released on 2024-04-30 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book discusses the applications of microorganisms as a crucial solution for the sustainable management of toxic pollutants. It describes the microbial remediation of different kinds of pollutants like wastewater, antibiotics, and toxic chemicals. It highlights the technical, scientific, regulatory, safety, and societal impacts of various sustainable biodegradation approaches. The book describes various sensors in environmental pollution monitoring and pollutant detection. KEY FEATURES Provides a deep understanding of the use of sensors in environmental water monitoring and pollutant detection Covers exciting topics like biological upcycling of plastic wastes into value-added chemicals Presents future research needs on biodegradation and scientific challenges in the mitigation of environmental pollutants Brings out the latest themes, such as eco-design study of bio-nanomaterials, bio-nanofilters, and assessment for the treatment of emerging pollutants Reviews the biodegradation of toxicants to improve the quality of water and air and environmental sustainability This book is meant for scientists, ecologists, microbiologists, industry experts, researchers, students, innovators involved in biotechnology research, and policymakers focused on bioremediation.

Endocrine Disruption and Human Health

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Publisher : Academic Press
ISBN 13 : 0128011203
Total Pages : 390 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Endocrine Disruption and Human Health by : Philippa D. Darbre

Download or read book Endocrine Disruption and Human Health written by Philippa D. Darbre and published by Academic Press. This book was released on 2015-03-21 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations

Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS)

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Author :
Publisher : CRC Press
ISBN 13 : 1000375889
Total Pages : 122 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) by : Mark S. Johnson

Download or read book Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) written by Mark S. Johnson and published by CRC Press. This book was released on 2021-04-22 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) provides the most recent summary of toxicity data relevant to mammals, birds, reptiles, and amphibians, and provides values for use in risk assessment applications. Predicting the bioaccumulation of PFAS in terrestrial wildlife (including humans) has proven to be extremely complex. As a group, PFAS act differently than traditional non-ionic organic molecules, where PFAS can break down and reform, whereas some are demonstrated to be extremely persistent. Where sufficient data are provided, this book establishes toxicity reference values (TRVs), which are derived to assist in characterizing environmental sources of contamination and making risk-based decisions. Features: Provides toxicity reference values (TRVs) for vertebrates (mammals, birds, amphibians) for PFAS, where sufficient data are available, and includes objective supporting background information. Assigns a level of confidence to each TRV to provide the risk assessor with an understanding of the relative uncertainty associated with each value. Presents toxicity data in the formats of scatter diagrams and tables for quick review and assessment. Provides TRVs relevant for screening and decision making This book serves as a useful aid for risk assessors and managers in those industries that have sites contaminated with PFAS, consultants tasked with evaluating risks at such sites, and staff at regulatory agencies at various governmental levels, who need to know how much contamination is considered safe for wildlife. It will also appeal to researchers with an interest in filling the gaps in the current toxicological data for PFAS exposure.

Cumulated Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 1200 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1971 with total page 1200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environmental Stressors and OxInflammatory Tissues Responses

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Publisher : CRC Press
ISBN 13 : 1000970108
Total Pages : 417 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Environmental Stressors and OxInflammatory Tissues Responses by : Giuseppe Valacchi

Download or read book Environmental Stressors and OxInflammatory Tissues Responses written by Giuseppe Valacchi and published by CRC Press. This book was released on 2023-12-15 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental risk factors – noise, air pollution, chemical agents, and ultraviolet radiation – impact human health by contributing to the onset and progression of noncommunicable diseases. Accordingly, there is need for preclinical and clinical studies and comprehensive summary of major findings. This book is a state-of-the-art summary of these myriad severe life stressors. The chapters on the different pollutants focus on disease mechanisms (cardiovascular, neurological and metabolic disorders) and on oxidative stress and inflammation. The editors emphasize emerging mechanisms based on dysregulation of the circadian clock, the microbiome, epigenetic pathways, and cognitive function by environmental stressors, and introduce the exposome concept while highlighting existing research gaps. Key Features: Links various environmental stressors to the incidence of noncommunicable diseases Includes chapters on airborne toxins, chemical pollutants, noise, and ultraviolet radiation stressors Contributions from an international team of leading researchers Summarizes the impacts of stressors on disease mechanisms

Per and polyfluorinated substances in the Nordic Countries

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Author :
Publisher : Nordic Council of Ministers
ISBN 13 : 9289325623
Total Pages : 230 pages
Book Rating : 4.2/5 (893 download)

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Book Synopsis Per and polyfluorinated substances in the Nordic Countries by : Stefan Posner

Download or read book Per and polyfluorinated substances in the Nordic Countries written by Stefan Posner and published by Nordic Council of Ministers. This book was released on 2013-06-19 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Tema Nord report presents a study based on open information and custom market research to review the most common perfluorinated substances (PFC) with less focus on PFOS and PFOA. The study includes three major parts:1) Identification of relevant per-and polyfluorinated substances and their use in various industrial sectors in the Nordic market by interviews with major players and database information; 2) Emissions to and occurence in the Nordic environment of the substances described in 1); 3) A summary of knowledge of the toxic effects on humans and the environment of substances prioritized in 2); There is a lack of physical chemical data, analystical reference substances, human and environmental occurrence and toxicology data, as well as market information regarding PFCs other than PFOA and PFOS and the current legislation cannot enforce disclosure of specific PFC substance information.

Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances

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Author :
Publisher : Humana Press
ISBN 13 : 3319155180
Total Pages : 500 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances by : Jamie C. DeWitt

Download or read book Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances written by Jamie C. DeWitt and published by Humana Press. This book was released on 2015-04-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.

Perfluoroalkyl Substances in the Environment

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Publisher : CRC Press
ISBN 13 : 0429945027
Total Pages : 495 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Perfluoroalkyl Substances in the Environment by : David M. Kempisty

Download or read book Perfluoroalkyl Substances in the Environment written by David M. Kempisty and published by CRC Press. This book was released on 2018-08-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Per- and polyfluorinated alkyl substances (PFAS), often referred to as per- (and poly) fluorinated compounds (PFCs), have been used for years in many everyday3⁄4 and some lifesaving3⁄4 products. However, their use has been linked to adverse health effects in humans, a problem compounded by their persistence in the environment. This book discusses the various challenges of PFAS in our environment today, including their historical use as well as their chemical and toxicological properties. It also presents robust discussion of analytical challenges and special considerations in sampling. The work goes on to give practical recommendations for dealing with these compounds in today's dynamic regulatory landscape and includes several chapters on various remediation techniques. Key Features: Comprehensive overview of per- and polyfluorinated alkyl substances (PFAS) historical use and chemical/physical properties which help us understand their persistence, transport, and transformation pathways in the environment In-depth analysis of PFAS toxicology Detailed descriptions of conventional and state-of-the-art remediation technologies Practical recommendations for dealing with PFAS in a dynamic regulatory landscape Robust discussion of important sampling and analytical considerations Perfluoroalkyl Substances in the Environment: Theory, Practice, and Innovation explores the challenges across the topical areas of regulation and management, toxicology, environmental remediation, and analytical sampling and analysis.Readers will find this text helpful in understanding complexities associated with PFAS and informing management strategies to effectively protect this and future generations.

Government Reports Annual Index

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Author :
Publisher :
ISBN 13 :
Total Pages : 1686 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Government Reports Annual Index by :

Download or read book Government Reports Annual Index written by and published by . This book was released on 1995 with total page 1686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sections 1-2. Keyword Index.--Section 3. Personal author index.--Section 4. Corporate author index.-- Section 5. Contract/grant number index, NTIS order/report number index 1-E.--Section 6. NTIS order/report number index F-Z.

Organofluorines

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540420644
Total Pages : 372 pages
Book Rating : 4.4/5 (26 download)

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Book Synopsis Organofluorines by : A.H. Neilson

Download or read book Organofluorines written by A.H. Neilson and published by Springer Science & Business Media. This book was released on 2002-07-03 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, written by a range of international experts, covers a wide range of topics involving organic fluorine compounds. Each chapter is preceded by a summary and includes extensive illustrations and references. The chapters cover atmospheric chemistry, application of 19F NMR, partition, degradation and transformation, naturally occurring organic fluorine compounds, toxicology of perfluoroalkanes and phosphorofluoridates, and application of aromatic compounds to the elucidation of the mechanism of cytochrome P450.

Peroxisome Proliferators

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Publisher : CRC Press
ISBN 13 : 9780849383052
Total Pages : 212 pages
Book Rating : 4.3/5 (83 download)

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Book Synopsis Peroxisome Proliferators by : David E. Moody

Download or read book Peroxisome Proliferators written by David E. Moody and published by CRC Press. This book was released on 1994-07-12 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Induction of drug (xenobiotic)-metabolizing enzymes is a common biological response to xenobiotics, the mechanisms and consequences of which are important in academic, industrial, and regulatory areas of pharmacology and toxicology. This monograph, for the first time, has brought together researchers who deal specifically with drug-metabolizing enzymes and peroxisome proliferators. It contains an up-to-date review of peroxisome proliferation, with detailed tables on the 100 known peroxisome proliferators and studies on their hepatocarcinogic capacity. It provides current material from 12 different laboratories doing cutting-edge research on the effect of peroxisome proliferators on drug-metabolizing enzymes.The book covers the response of cytochrome P450s, UDP-glucuronosyltransferases, epoxide hydrolases, glutathione S-transferase, DT-diaphorase, and other enzymes.

Environmental Forensics for Persistent Organic Pollutants

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Publisher : Newnes
ISBN 13 : 0444594515
Total Pages : 424 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Environmental Forensics for Persistent Organic Pollutants by : Gwen O'Sullivan

Download or read book Environmental Forensics for Persistent Organic Pollutants written by Gwen O'Sullivan and published by Newnes. This book was released on 2013-11-20 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Forensics for Persistent Organic Pollutants represents the state-of-the-art in environmental forensics in relation to persistent organic pollutants (POPs). The book is a complete reference for practitioners and students, covering a range of topics from new analytical techniques to regulatory and legal status in the global community. Through case studies from leading international experts, real-world issues — including the allocation of responsibility for release into the environment — are resolved through the application of advanced analytical and scientific techniques. This book introduces and assesses the development of new techniques and technologies to trace the source and fate of newly emerging and classic POPs (perfluoroalkyl substances, brominated flame retardants, organochlorine pesticides, perfluorinated chemicals, polycyclic aromatic hydrocarbons, and polychlorinated biphenyls) in environmental media, including atmospheric, marine, freshwater, and urban environments. - Real-world case studies show the application of advanced analytical and scientific techniques - Discussion of GC*GC provides an introduction and assessment of a novel technique from leaders in the field - Introduces the development of new analytical techniques (such as 2-D GC*HC and LC*LC) to trace the source and fate - Raises awareness about the health and environmental impact of persistent organic pollutants (POPs) - Outlines the development of international measures to control POPs so that chemists can understand the legal issues

Government Reports Announcements & Index

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Author :
Publisher :
ISBN 13 :
Total Pages : 476 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Government Reports Announcements & Index by :

Download or read book Government Reports Announcements & Index written by and published by . This book was released on 1996 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: