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Hepatic Encephalopathy Hyperammonemia And Ammonia Toxicity
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Book Synopsis Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity by : Vicente Felipo
Download or read book Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity written by Vicente Felipo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers presented at the International Symposium on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy", held in Valencia, Spain, January 24th-27th, 1994. Liver cirrhosis and other hepatic dysfunctions such as fulminant hepatic failure and congenital defects of urea cycle enzymes can lead to hepatic encephalopathy, coma and death. Hepatic encephalopathy is one of the main causes of death in western countries. The ability to detoxify ammonia by its incorporation into urea is diminished by impaired liver function, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. However, the molecular bases of the pathogenesis of hepatic encephalopathy and the role of hyperammonemia in this process remain unclear and several hypotheses have been proposed. To clarify the mechanisms involved in hepatic encephalopathy and hyperammonemia suitable animal models are necessary. The animal models available and the ideal features of an animal model are presented in the initial part of the book.
Book Synopsis Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy by : Santiago Grisolía
Download or read book Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy written by Santiago Grisolía and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers presented in the International Summer Course on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy," which was one of the prestigious Summer Course, of the Complutense University of Madrid held in EI Escorial, Spain, during August 10-14, 1992. Liver cirrhosis is one of the main causes of death in western countries. In addition there is a series of liver dysfunctions including fulminant hepatic failure, Reye's syndrome and congenital defects of urea cycle enzymes that could lead to hepatic encephalopathy, coma and death. As a consequence of impaired liver function, the ability to detoxify ammonia by its incorporation into urea is diminshed, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. A part of the book is therefore devoted to the study of certain aspects of ammonia metabolism such as the regulation of the urea cycle, the main mechanism of ammonia detoxification in mammals, which is located mainly in the liver. The metabolism of ammonia in other tissues, including brain, is also presented, as well as the effects of hyperammonemia on brain metabolism and function and on brain microtubules. The control of cerebral protein breakdown is reviewed. The classical and some recently proposed clinical treatments as well as nutritional considerations in the management of patients with liver failure are also discussed.
Book Synopsis Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy by : Vicente Felipo
Download or read book Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy written by Vicente Felipo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an international symposiu, held in Valencia, Spain, December 2-4, 1996
Book Synopsis Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity by : Santiago Grisolía
Download or read book Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity written by Santiago Grisolía and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an international symposium held in Valencia, Spain, November 27--29, 1989
Book Synopsis Hepatic Encephalopathy by : Roger F. Butterworth
Download or read book Hepatic Encephalopathy written by Roger F. Butterworth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Hepatic Encephalopathy by : Frederick Steigmann
Download or read book Hepatic Encephalopathy written by Frederick Steigmann and published by . This book was released on 1971 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Hepatic Encephalopathy by : Kevin D. Mullen
Download or read book Hepatic Encephalopathy written by Kevin D. Mullen and published by Springer Science & Business Media. This book was released on 2012-05-30 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of the increasing burden of hepatitis C and fatty liver disease, there is an explosion in the prevalence of chronic liver failure and hence its complications. The onset of Hepatic Encephalopathy (HE) in these patients has a significant impact on the quality of life, morbidity and mortality. Unfortunately, the approach observed by most clinicians to this complex disorder is minimalistic. This book provides a comprehensive review on pathophysiology and clinically important aspects in HE. Topics in basic physiology, nitrogen metabolism, new insights into pathogenesis and brain edema are covered in great detail. The authors have made a special effort by simplifying the complex aspects of pathogenesis and diagnosis so that it can be easily understood and applied clinically. This volume also focuses on recent developments regarding diagnoses of subtle forms of HE, also known as minimal or covert HE as well as on new treatments. Hepatic Encephalopathy will be of great value to gastroenterologists, hepatologists, pathologists, medical residents, fellows, internists and general practitioners who treat patients with hepatic encephalopathy.
Book Synopsis Encephalopathy and Nitrogen Metabolism in Liver Failure by : E. Anthony Jones
Download or read book Encephalopathy and Nitrogen Metabolism in Liver Failure written by E. Anthony Jones and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encephalopathy and Nitrogen Metabolism in Liver Failure contains research reports and state-of-the-art reviews that were presented at the 11th International Symposium on Hepatic Encephalopathy and Nitrogen Metabolism in relation to liver disease, that was held in Amsterdam, The Netherlands from 30 May to 1 June, 2002. Themes covered include the metabolism of ammonia and amino acids in relation to liver disease, the assessment of hepatic encephalopathy (HE), minimal HE, animal models of HE, neuropsychiatric dysfunction in patients with chronic liver disease, the pathogenesis of HE, the astrocyte in liver disease, acute liver failure and cerebral edema, treatment of HE and artificial liver support systems. This volume provides an indispensable source of important new research findings and ideas for clinicians and biomedical scientists working in the field of HE and nitrogen metabolism in relation to liver disease.
Book Synopsis Biomarkers in Inborn Errors of Metabolism by : Uttam Garg
Download or read book Biomarkers in Inborn Errors of Metabolism written by Uttam Garg and published by Elsevier. This book was released on 2017-06-07 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future. Provides comprehensive information on the tests/biomarkers selection in newborn screening and follow-up of newborn screens Categorizes biomarkers into diagnostic markers, disease follow-up markers, and prognostic biomarkers Covers confounding factors that can alter biomarkers in the absence of inborn errors of metabolism Offers guidance on how to distinguish acquired causes from inborn errors of metabolism
Book Synopsis Diet and Nutrition in Critical Care by : Rajkumar Rajendram
Download or read book Diet and Nutrition in Critical Care written by Rajkumar Rajendram and published by Springer. This book was released on 2015-06-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finding all the information necessary to treat or meet the nutritional requirements of patients who are severely ill or establish new protocols has historically been problematic. This is addressed in Diet and Nutrition in Critical Care. This major reference work encapsulates the latest treatments and procedures to meet the dietary and nutritional needs of the critically ill. Where evidence is available this is presented. However, where evidence is absent, the authors highlight this and provide guidance based on their analysis of other available data and their clinical experience. Diet and Nutrition in Critical Care is a three volume set which addresses the needs of all those concerned with diet and nutrition in the critically ill and covers General Aspects, Enteral Aspects, and Parenteral Aspects. Each volume is stand alone and is further divided into separate sections. The Sections in the General Aspects are: General conditions in the severely ill General metabolic effects and treatments Assessment protocols General nutritional aspects Specific nutrients Adverse aspects The next two volumes Enteral Aspects and Parenteral Aspects contain the following sections: General aspects and methods Specific nutrients Specific conditions Adverse aspects and outcomes Comparisons or dual parenteral and enteral support or transitions Preclinical studies The authors recognise the limitations in simplistic divisions and there is always difficulty in categorising treatment regimens. For example, some regimens involve transitions from one feeding protocol to another or the development of co-morbid conditions and in some cases enteral support may be supplemented with parenteral support. This complexity however, is addressed by the excellent indexing system. Contributors are authors of international and national standing, leaders in the field and trendsetters. Emerging fields of science and important discoveries relating to artificial support will also be incorporated into Diet and Nutrition in Critical Care. This volume represents a one stop shop of material related to enteral and parenteral support and is essential reading for those specialising in intensive and critical care, dietitians, nutritionists, gastroenterologists, cardiologists, pharmacologists, health care professionals, research scientists, molecular or cellular biochemists, general practitioners as well as those interested in diet and nutrition in general.
Book Synopsis Hepatic Encephalopathy by : Alan H. Lockwood
Download or read book Hepatic Encephalopathy written by Alan H. Lockwood and published by Butterworth-Heinemann. This book was released on 1992 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Hepatic Encephalopathy and Urea Cycle Diseases by : Gunter Kleinberger
Download or read book Advances in Hepatic Encephalopathy and Urea Cycle Diseases written by Gunter Kleinberger and published by S. Karger AG (Switzerland). This book was released on 1984 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Equine Neurology written by Martin Furr and published by John Wiley & Sons. This book was released on 2015-04-09 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Equine Neurology, Second Edition provides a fully updated new edition of the only equine-specific neurology book, with comprehensive, clinically oriented information. Offers a complete clinical reference to neurologic conditions in equine patients Takes a problem-based approach to present a clinically oriented perspective Presents new chapters on imaging the nervous system, neuronal physiology, sleep disorders, head shaking, differential diagnosis of muscle trembling and weakness, and cervical articular process joint disease Covers the basic principles of neurology, clinical topics such as the initial exam, differentials, and neuropathology, and specific conditions and disorders Includes access to a companion website offering video clips demonstrating presenting signs
Book Synopsis Handbook of Liver Disease by : Lawrence Samuel Friedman
Download or read book Handbook of Liver Disease written by Lawrence Samuel Friedman and published by . This book was released on 2004 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here's instant access to the symptoms, signs, differential diagnosis, and treatment for the full range of liver disorders. Written by an international 'who's who' of hepatology-and now in full color-this new 2nd Edition provides readers with top-notch, authoritative guidance they can count on! Discusses the hottest topics in the field, such as non-alcoholic steatohepatitis (NASH) and the latest information on liver transplantation. Includes expanded coverage of chronic hepatitis C, most notably the use of combination therapy with peginterferon and ribavirin and improvements in the management of the side effects of antiviral therapy. Offers the most recent therapeutic options for the management of chronic hepatitis B and advances in the understanding of the molecular biology of this virus. Updates the approach to the diagnosis of many liver diseases due to newer tests based on molecular techniques and advances in imaging. Features over 340 full-color illustrations. Uses a redesigned templated, outline format that makes reference a snap. Presents a concise, in-depth clinical summary-in an outline format-of the current practice of hepatology for each major disease entity. Provides a liberal use of tables, algorithms, and figures, rendering complex concepts understandable. Includes key point boxes at the beginning of each chapter, providing at-a-glance access to vital information. Includes alert symbols that highlight information that's critical to patient safety.
Book Synopsis Chronic Liver Failure by : Pere Ginès
Download or read book Chronic Liver Failure written by Pere Ginès and published by Springer Science & Business Media. This book was released on 2010-11-03 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
Book Synopsis Quick Guide to Psychiatric Emergencies by : Kimberly D. Nordstrom
Download or read book Quick Guide to Psychiatric Emergencies written by Kimberly D. Nordstrom and published by Springer. This book was released on 2018-03-07 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an “on-the-go” guide to the most common behavioral emergencies a physician may encounter. Each chapter represents a disease state or symptom cluster and concisely summarizes the disease state, provides background, symptoms and signs, differential diagnoses, and immediate and long-term treatment options. All chapters conclude with a diagnosis or treatment algorithm or another easy-to-use visual tool. Chapters named after a specific disease state or symptom cluster, arranged alphabetically for use in the field. The text begins with chapters covering patient evaluation: getting a good history, suicide risk assessment, physical exam, and when and how to use studies. Written by experts in psychiatry and emergency medicine, this text is the first to consider both medical perspectives in a concise guide. Quick Guide to Psychiatric Emergencies is an excellent resource for psychiatrists, emergency medicine physicians, residents, nurses, and other medical professionals that handle behavioral emergencies on a regular basis.
Book Synopsis Bile Acids and Their Receptors by : Stefano Fiorucci
Download or read book Bile Acids and Their Receptors written by Stefano Fiorucci and published by Springer Nature. This book was released on 2019-09-03 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to clinical applications, offering a cross-country view of the functional role of bile acids as signaling molecules, virtually acting on all major areas of metabolism. While FXR and GPBAR1 are essential bile acid sensors that integrate the de novo bile acid synthesis with intestinal microbiota and liver metabolism, in a broader sense, BARs play a pathogenic role in the development of common human alignments including liver, intestinal and metabolic disorders, such as steatosis (NAFLD) and steato-hepatitis (NASH), diabetes, obesity and atherosclerosis.
