Hemoglobinopathies Advances In Research And Treatment 2013 Edition

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Hemoglobinopathies: Advances in Research and Treatment: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464947139
Total Pages : 29 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Hemoglobinopathies: Advances in Research and Treatment: 2011 Edition by :

Download or read book Hemoglobinopathies: Advances in Research and Treatment: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobinopathies: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Hemoglobinopathies in a compact format. The editors have built Hemoglobinopathies: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hemoglobinopathies in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemoglobinopathies: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481688634
Total Pages : 28 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition by :

Download or read book Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about ZZZAdditional Research in a compact format. The editors have built Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481676423
Total Pages : 30 pages
Book Rating : 4.4/5 (816 download)

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Download or read book Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about ZZZAdditional Research in a compact format. The editors have built Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemoglobinopathies—Advances in Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Hemoglobinopathies—Advances in Research and Treatment: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481623702
Total Pages : 33 pages
Book Rating : 4.4/5 (816 download)

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Download or read book Hemoglobinopathies—Advances in Research and Treatment: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobinopathies—Advances in Research and Treatment: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Hemoglobinopathies in a compact format. The editors have built Hemoglobinopathies—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hemoglobinopathies in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemoglobinopathies—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The EBMT Handbook

Author : Nicolaus Kröger
Publisher :
ISBN 13 : 9781013273674
Total Pages : 688 pages
Book Rating : 4.2/5 (736 download)

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Book Synopsis The EBMT Handbook by : Nicolaus Kröger

Download or read book The EBMT Handbook written by Nicolaus Kröger and published by . This book was released on 2020-10-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Amidohydrolases—Advances in Research and Application: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481672568
Total Pages : 371 pages
Book Rating : 4.4/5 (816 download)

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Download or read book Amidohydrolases—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amidohydrolases—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Dihydroorotase. The editors have built Amidohydrolases—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Dihydroorotase in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Amidohydrolases—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Lung Diseases—Advances in Research and Treatment: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481689541
Total Pages : 179 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Lung Diseases—Advances in Research and Treatment: 2013 Edition by :

Download or read book Lung Diseases—Advances in Research and Treatment: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung Diseases—Advances in Research and Treatment: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Pulmonary Fibrosis. The editors have built Lung Diseases—Advances in Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pulmonary Fibrosis in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lung Diseases—Advances in Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Phthalimides—Advances in Research and Application: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481691376
Total Pages : 61 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Phthalimides—Advances in Research and Application: 2013 Edition by :

Download or read book Phthalimides—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phthalimides—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Phthalimides—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Phthalimides—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Thalassemia and Other Hemolytic Anemias

Author : Isam Jaber Al-Zwaini
Publisher : BoD – Books on Demand
ISBN 13 : 1789233666
Total Pages : 140 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Thalassemia and Other Hemolytic Anemias by : Isam Jaber Al-Zwaini

Download or read book Thalassemia and Other Hemolytic Anemias written by Isam Jaber Al-Zwaini and published by BoD – Books on Demand. This book was released on 2018-07-11 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thalassemia is a very common disease first described by pediatrician Thomas Benton Cooley in 1925 who described it in a patient of Italian origin. At that time, it was designated as Cooley's anemia. George Hoyt Whipple, a Nobel prize winner, and W. L. Bradford, a professor of pediatrics at the University of Rochester, coined the term thalassemia in 1936, which in Greek means anemia of the sea (Thalassa means "sea", and emia means "blood"), due to the fact that it is very common in the area of the Mediterranean Sea. This name is actually misleading because it can occur everywhere in the world. Thalassemia is not a single disease; it is rather a group of hereditary disorders of the production of globulin chain of the hemoglobin. Throughout the world, thalassemia affects approximately 4.4 of every 10,000 live births. It represents a major social and emotional impact on the patient and his family and a major burden on health services where the prevalence is high.

Gene and Cell Therapies for Beta-Globinopathies

Author : Punam Malik
Publisher : Springer
ISBN 13 : 1493972995
Total Pages : 254 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Gene and Cell Therapies for Beta-Globinopathies by : Punam Malik

Download or read book Gene and Cell Therapies for Beta-Globinopathies written by Punam Malik and published by Springer. This book was released on 2017-11-09 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobin defects, specifically sickle cell disease & thalassemia, combined, constitute the most common monogenic disorders in the world. In fact, nearly 2% of the world’s population carries a globin gene mutation. The transfer of the corrective globin gene through the HSC compartment by allogeneic HSC transplantation (HSCT) has already proven curative in both SCD and thalassemia patients, and provides the proof of concept that genetic manipulation of the defective organ might be equally therapeutic. However, procedural toxicities and the requirement of an HLA-matched sibling donor limit this approach to a fraction of affected individuals. The editors review the progress & the state of the field in HSCT for hemoglobinopathies & shed light on the major changes expected in the next decade. Although allogeneic HSCT is a curative option, it is limited by the availability of matched donors, which are often available only to 15-20% of patients. An alternative to allogeneic HS CT is genetic correction of autologous HSCs, to overcome donor availability & immune side effects. This Book reviews the progress made on additive gene therapy approaches & the current state of the field. Finally, targeted genetic correction is emerging as a novel therapeutic strategy in the hemoglobinopathies. Although ideal, the inefficiency of targeted correction was rate limiting for translation of this technology to the clinic. With advancements in zinc finger nucleases and TALE endonuclease mediated targeted correction, correction frequencies in hematopoietic stem cells is now reaching levels that may become clinically relevant. Furthermore, the ability to generate autologous embryonic stem cell like cells from primary somatic cells (skin fibroblasts or hematopoietic cells) of the affected individual has allowed for the potential application of genetic correction strategies.This Book reviews upcoming genetic strategies to reactivate fetal hemoglobin production and research advances.

Vogel and Motulsky's Human Genetics

Author : Michael Speicher
Publisher : Springer Science & Business Media
ISBN 13 : 3540376542
Total Pages : 1006 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Vogel and Motulsky's Human Genetics by : Michael Speicher

Download or read book Vogel and Motulsky's Human Genetics written by Michael Speicher and published by Springer Science & Business Media. This book was released on 2009-11-26 with total page 1006 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of this classical reference book can once again be relied upon to present a cohesive and up-to-date exposition of all aspects of human and medical genetics. Human genetics has become one of the main basic sciences in medicine, and molecular genetics is increasingly becoming a major part of this field. This new edition integrates a wealth of new information - mainly describing the influence of the "molecular revolution" - including the principles of epigenetic processes which together create the phenotype of a human being. Other revisions are an improved layout, sub-division into a larger number of chapters, as well as two-colour print throughout for ease of reference, and many of the figures are now in full colour. For graduates and those already working in medical genetics.

Prevention of Thalassaemias and Other Haemoglobin Disorders

Author : Galanello Renzo
Publisher :
ISBN 13 : 9789963623396
Total Pages : 190 pages
Book Rating : 4.6/5 (233 download)

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Book Synopsis Prevention of Thalassaemias and Other Haemoglobin Disorders by : Galanello Renzo

Download or read book Prevention of Thalassaemias and Other Haemoglobin Disorders written by Galanello Renzo and published by . This book was released on 2003 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 1 of the Prevention Book presents the principles of a programme for the prevention of the thalassaemia and other haemoglobin disorders, including a description of the various types of disorders requiring prenatal diagnosis, the strategies used for carrier screening, and a number of annexes listing upto date epidemiological and mutation data on thalassaemia. This book was written for use in combination with Volume 2, which describes many of the laboratory protocols in great detail.

Disorders of Hemoglobin

Author : Martin H. Steinberg
Publisher : Cambridge University Press
ISBN 13 : 0521875196
Total Pages : 883 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Disorders of Hemoglobin by : Martin H. Steinberg

Download or read book Disorders of Hemoglobin written by Martin H. Steinberg and published by Cambridge University Press. This book was released on 2009-08-17 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the definitive reference on disorders of hemoglobin.

Hemoglobin Disorders

Author : Ronald L. Nagel
Publisher : Springer Science & Business Media
ISBN 13 : 1592593739
Total Pages : 311 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Hemoglobin Disorders by : Ronald L. Nagel

Download or read book Hemoglobin Disorders written by Ronald L. Nagel and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobin and Hemoglobinologists This volume, Hemoglobin Disorders: Molecular Methods and Protocols, will be introduced with a review of the great milestones in the field, and the scientists responsible for those achievements. The history of hemoglobin can be divided into three periods: the Classical period, the Modern period, and the Post-Modern period. I am inclined to include as the four major members of the classical period Francis Roughton, Quentin Gibson, Jeffries Wyman, and Linus Pauling, not only because of their achievements, but also because of the superb scientists they trained and/or influenced. Francis John Worsely Roughton (1899–1972) (Fig. 1), in his laboratory at Trinity College in Cambridge, England, made the first measurements of the rapid reaction of oxygen with hemoglobin at the millisecond scale, at first by flow-mixing methods and later by flash photolysis. He not only opened an era of molecular research of hemoglobin, but also invented the methodology for fast reactions through the use of laser technology, which was later improved by others so that even faster reactions could be detected. Another contribution of Roughton was the education of Quentin H. Gibson (Fig. 2), his favorite s- dent, who, in his laboratory in Sheffield, continued to expand the horizon of ligand binding to hemoglobin, defining the oxygen binding constants for each of the hemes of hemoglobin. Though this did not, as expected, solve the und- lying mechanism of ligand cooperativity as discussed below, it was nonet- less an important milestone.

Iron Chelation Therapy

Author : Chaim Hershko
Publisher : Springer Science & Business Media
ISBN 13 : 1461505933
Total Pages : 275 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Iron Chelation Therapy by : Chaim Hershko

Download or read book Iron Chelation Therapy written by Chaim Hershko and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).

The Obstetric Hematology Manual

Author : Sue Pavord
Publisher : Cambridge University Press
ISBN 13 : 1108548377
Total Pages : 362 pages
Book Rating : 4.1/5 (85 download)

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Book Synopsis The Obstetric Hematology Manual by : Sue Pavord

Download or read book The Obstetric Hematology Manual written by Sue Pavord and published by Cambridge University Press. This book was released on 2018-02-08 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.

Human Hemoglobin Genetics

Author : G.R. Honig
Publisher : Springer Science & Business Media
ISBN 13 : 3709187982
Total Pages : 460 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Human Hemoglobin Genetics by : G.R. Honig

Download or read book Human Hemoglobin Genetics written by G.R. Honig and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery in the late 1940's that sickle cell anemia is a "molecular disease" of hemoglobin was the crucial advance that gave birth to the scientific discipline of human molecular genetics. In subsequent years, with the continued expansion of knowledge about the biology and genetics of the hemoglobins, and particularly as a result of the characterization of the very large numbers of globin gene mutations, the human hemoglobin system has remained as the premier model of gene expression at the molecular level in man. With the recent explosion of new information about the genetic properties of the hemoglobins, it appears inevitable that this gene system will continue to occupy a unique position in human molecular genetics for many years in the future. Hemoglobin genetics has also recently come of age as a diagnostic and clinical discipline. The heightening of public awareness in recent years about sickle cell disease, thalassemia, and other inherited disorders has brought increasing demands for carrier detection services as well as for genetic counseling and education. The more recent development of prac tical and reliable methods for the antenatal diagnosis of hemoglobin dis orders has further increased the scope of clinical hemoglobin genetics, and it can be anticipated that these potent diagnostic techniques will have increasing application in the years ahead.