Stem Cells and the Future of Regenerative Medicine

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Publisher : National Academies Press
ISBN 13 : 0309170427
Total Pages : 112 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stem Cells and the Future of Regenerative Medicine by : Institute of Medicine

Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Hematopoietic Stem Cells 2002

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Publisher :
ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Hematopoietic Stem Cells 2002 by : Donald Orlic

Download or read book Hematopoietic Stem Cells 2002 written by Donald Orlic and published by . This book was released on 2003 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of haematopoietic stem cell genetics, development and transplantation is advancing rapidly. Collecting the proceedings of the 4th Hematopoietic Stem Cells International Conference and Workshop, this volume presents basic and clinical findings in stem cell biology in vivo and in vitro, with an emphasis on the plasticity of stem cells. There are 25 papers from international scientists altogether.

Hematopoietic Stem Cells

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Author :
Publisher : Springer Nature
ISBN 13 : 9819974712
Total Pages : 218 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Hematopoietic Stem Cells by : Meng Zhao

Download or read book Hematopoietic Stem Cells written by Meng Zhao and published by Springer Nature. This book was released on 2024-01-17 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book renders a comprehensive understanding of hematopoietic stem cells (HSCs) from their embryonic development through adult maintenance to aging, in the studies conducted in zebrafish and mammals. Hematopoiesis provides a paradigm for understanding the development, maintenance, regeneration, aging and malignant transformation of mammalian organs. Sitting at the apex of the hematopoiesis hierarchy tree, HSCs orchestrate their proliferation, self-renewal, and differentiation to produce all the blood cell lineages throughout life, which represents the best example for somatic stem cell studies. In this book, key regulatory mechanisms for HSC self-renewal and differentiation are overviewed in an array of fields including epigenetics, metabolism and microenvironment regulation. It also highlights the HSC heterogeneity and clonal dynamics from the recent advanced single-cell technologies. This book elaborates on the research history of HSC studies and reveals how the insights from HSC studies shed light on their clinic application. It presents great value from the bench to the clinic.

Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642468365
Total Pages : 159 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy by : Rainer Haas

Download or read book Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy written by Rainer Haas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood stem cell transplantation has become an established therapeutic option in the treatment of malignant diseases. At the same time molecular therapeutic approaches (i.e. gene therapy) are promising alternatives to the classical treatment of cancer. The proceedings give an overview of the biology of hematopoietic progenitor cells, peripheral stem cell transplantation in patients with hematological malignancies, recent developments in molecular diagnosis and gene therapeutic concepts, and show that successful future developments require cooperative research connecting basic science with clinical application.

Hematopoietic Stem Cells

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Publisher : Springer Nature
ISBN 13 : 1071626795
Total Pages : 284 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Hematopoietic Stem Cells by : Louis M. Pelus

Download or read book Hematopoietic Stem Cells written by Louis M. Pelus and published by Springer Nature. This book was released on 2022-10-18 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume collects updates on the technical advances in hematopoietic stem cell research and incorporates new techniques focused on the molecular/genetic, cellular, and whole organism levels. Exploring methods that apply stress to hematopoiesis, the book also contains chapters focused on better understanding the role of hematopoietic niches and their cellular components, as well as in vivo models that test and quantitate stem cell function and are key to further development of therapeutic applications. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Hematopoietic Stem Cells: Methods and Protocols serves as a valued addition to laboratories focused on understanding hematopoietic stem cell biology and the therapeutic advances that can be derived from it.

Hematopoietic Stem Cell Development

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Publisher : Springer Science & Business Media
ISBN 13 : 0387335358
Total Pages : 188 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Hematopoietic Stem Cell Development by : Isabelle Godin

Download or read book Hematopoietic Stem Cell Development written by Isabelle Godin and published by Springer Science & Business Media. This book was released on 2010-05-27 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects articles on the biology of hematopoietic stem cells during embryonic development, reporting on fly, fish, avian and mammalian models. The text invites a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing conserved trends in development. The book reviews current knowledge on human hematopoietic development and discusses recent breakthroughs of relevance to both researchers and clinicians.

The EBMT Handbook

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Publisher :
ISBN 13 : 9781013273674
Total Pages : 688 pages
Book Rating : 4.2/5 (736 download)

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Book Synopsis The EBMT Handbook by : Nicolaus Kröger

Download or read book The EBMT Handbook written by Nicolaus Kröger and published by . This book was released on 2020-10-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Hematopoietic Stem Cell Transplantation

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Publisher : CRC Press
ISBN 13 : 0824741811
Total Pages : 610 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Hematopoietic Stem Cell Transplantation by : Anthony D. Ho

Download or read book Hematopoietic Stem Cell Transplantation written by Anthony D. Ho and published by CRC Press. This book was released on 2000-07-25 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion

Hematopoietic Stem Cell Niche

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Publisher : Elsevier
ISBN 13 : 0128113766
Total Pages : 188 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Hematopoietic Stem Cell Niche by :

Download or read book Hematopoietic Stem Cell Niche written by and published by Elsevier. This book was released on 2017-03-10 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hematopoietic Stem Cell Niche focuses on an individual organ, looking at the stem cells in the organ itself (if they exist), their niches, and how to use them alongside relevant methods and protocols. This series addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments, such as new data on disease and clinical applications. Specific chapters delve into the evolution of hematopoietic stem cell niches, the role of CNS in the regulation of HSCs, and targeting the bone marrow niche in hematological malignancies. In addition, video content illustrates protocols, transplantation techniques, and work with mice. Explores not only reviews of research, but also shares methods, protocols, and transplantation techniques Contains video content to illustrate such areas as protocols, transplantation techniques, and work with mice Each volume concentrates on one organ, making this a unique publication

Hematopoietic Stem Cells

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Publisher :
ISBN 13 :
Total Pages : 422 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Hematopoietic Stem Cells by : Donald Orlic

Download or read book Hematopoietic Stem Cells written by Donald Orlic and published by . This book was released on 1999 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the latest in vitro and in vivo studies on haematopoietic stem cell (HSC) biology. These include new data on: molecular controls; microenvironment; gene therapy; animal models of haematopoiesis; and clinical applications. The concept that HSCs are immortal and possess multiple developmental capabilities has always intrigued researchers in this field. Data presented at this conference demonstrate that major insights into these fundamental characteristics of HSC may soon be achieved.

Hematopoietic Stem Cell Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 1603273476
Total Pages : 260 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Hematopoietic Stem Cell Biology by : Motonari Kondo

Download or read book Hematopoietic Stem Cell Biology written by Motonari Kondo and published by Springer Science & Business Media. This book was released on 2009-12-04 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in a 1988 edition of the journal Science. It has been over 20 years since the publication of that seminal paper, and since then tremendous advances in understanding the biology and maturation of HSCs, namely the process of hematopoiesis, which includes lymphocyte development, have been made. These discoveries were made possible in part by advancements in technology. For example, recent availability of user friendly fluorescence activated cell sorting (FACS) machines and monoclonal an- bodies with a variety of fluorescent labels has allowed more scientists to sort and analyze rare populations in the bone marrow, such as HSCs. All classes of hematopoietic cells are derived from HSCs. Stem cell biology draws enormous attention not only from scientists, but also from ordinary people because of the tremendous potential for development of new therapeutic application to diseases that currently lack any type of effective therapy. Thus, this type of “regenerative medicine” is a relatively new and attractive field in both basic science and clinical medicine.

Hematopoietic Stem Cell Protocols

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Publisher : Springer Science & Business Media
ISBN 13 : 158829868X
Total Pages : 306 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Hematopoietic Stem Cell Protocols by : Kevin D. Bunting

Download or read book Hematopoietic Stem Cell Protocols written by Kevin D. Bunting and published by Springer Science & Business Media. This book was released on 2008-01-31 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition provides up-to-date protocols developed in the HSC field. A team of leading researchers supply this volume with in-depth, readily reproducible methods for effective characterization of HSC and their developmental potential. The book provides detailed flow cytometry protocols for thorough analysis of enriched HSC populations, and offers a variety of transplantation approaches to measure HSC function in vivo. This is a much needed technical resource in the critically important field of stem cell investigation.

Basics of Hematopoietic Stem Cell Transplant

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Publisher : Springer Nature
ISBN 13 : 9811958025
Total Pages : 962 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Basics of Hematopoietic Stem Cell Transplant by : Sanjeev Kumar Sharma

Download or read book Basics of Hematopoietic Stem Cell Transplant written by Sanjeev Kumar Sharma and published by Springer Nature. This book was released on 2023-07-24 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is quick guide on the hematopoietic stem cell transplant (SCT), also called bone marrow transplant (BMT) - an evolving field of hematology and hemato-oncology. This book covers the various types of stem cell transplants like autologous and allogeneic stem cell transplants, indications, ways of doing a transplant, and stem cell transplants basic principles. Written in a question-answer format, readers will find it more interesting as one question sequentially leads to another. This book explains the complications of SCT in individual chapters along with the biology of T cells which are the most important cells involved in the success of SCT This book is beneficial to the budding hematologists, oncologists, and postgraduates interested in SCT and helps students in their exams. The book would be helpful for readers globally as SCT is a procedure done worldwide and is an ever-increasing field for treating various benign and malignant hematological diseases.

Stem Cells from Cord Blood, in Utero Stem Cell Development and Transplantation-Inclusive Gene Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3662044692
Total Pages : 265 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Stem Cells from Cord Blood, in Utero Stem Cell Development and Transplantation-Inclusive Gene Therapy by : W. Holzgreve

Download or read book Stem Cells from Cord Blood, in Utero Stem Cell Development and Transplantation-Inclusive Gene Therapy written by W. Holzgreve and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The title "Stem Cells from Cord Blood, In Utero Stem Cell Develop ment, and Transplantation-Inclusive Gene Therapy" suggests that more than one topic is combined in one workshop. Indeed, at first glance the recovery of stem cells from cord blood has to be seen as separate from the attempts to achieve effective in utero therapy by stem cell trans plantation, because the first issue deals with an innovative stem cell source as an alternative to bone marrow, which is already spreading rapidly in medical practice, whereas the second topic is still strictly ex perimental and only investigated in medical centers with the appropri ate background. It is, however, not only justified, but helpful to com bine the two topics in one workshop and consequently to cover them in the same volume of the Ernst Schering Research Foundation Work shop series, because they are intimately related and both based on the new insights into the biology of stem cells. Professor Werner Arber, the Nobel Laureate from the University of Basel, pointed out in his In- Professor Dr. W. Holzgreve VI Preface The participants of the workshop troductory Lecture that our understanding of hematopoietic stem cells as descendents of totipotent cells and our current approaches to using them in post-and prenatal therapy have been furthered significantly by genetic engineering technologies which are "artificial contributions to the process of biologic evolution".

Hematopoietic Stem Cells V

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Publisher : Wiley-Blackwell
ISBN 13 : 9781573315890
Total Pages : 248 pages
Book Rating : 4.3/5 (158 download)

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Book Synopsis Hematopoietic Stem Cells V by : Lothar Kanz

Download or read book Hematopoietic Stem Cells V written by Lothar Kanz and published by Wiley-Blackwell. This book was released on 2005-06-24 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most recent developments in hematopoietic stem cell research are presented in this volume, along with their clinical implications. The field of hematopoietic stem cell biology is rapidly advancing, and new ideas and concepts supported by fascinating new technologies captivated the interest and excitement of the participants of the meeting. The sharing of new ideas and technologies with other scientists represents an invaluable stimulus, particularly for the young investigators in the field. It is hoped that the spirit of the meeting will be carried forward to the readers of this volume and that its content will stimulate new and fruitful projects in the field of stem cell biology. The major topics covered are genetic and epigenetic regulation of stem cells, stem cell plasticity, stem cell regulation and self-renewal, and embryonic stem cells as well as malignant stem cell biology. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Hematopoietic Stem Cells V

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Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Hematopoietic Stem Cells V by : Lothar Kanz

Download or read book Hematopoietic Stem Cells V written by Lothar Kanz and published by . This book was released on 2005 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, contributing scientists discuss the most recent developments in hematopoietic stem cell research and their clinical implications. The major topics covered are genetic and epigenetic regulation of stem cells, stem cell plasticity, stem cell regulation and self-renewal, embryonic stem cells as well as malignant stem cell biology. The field of hematopoietic stem cell biology is rapidly advancing, and new ideas and concepts supported by fascinating new technologies captivated the interest and excitement of the participants of the meeting. The sharing of new ideas and technologies with other scientists represents an invaluable stimulus, particularly for the young investigators in the field. It is hoped that the spirit of the meeting will be carried forward to the readers of this volume and that its content will stimulate new and fruitful projects in the field of stem cell biology.

Clinical Bone Marrow and Blood Stem Cell Transplantation

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9780521829120
Total Pages : 2210 pages
Book Rating : 4.8/5 (291 download)

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Book Synopsis Clinical Bone Marrow and Blood Stem Cell Transplantation by : Kerry Atkinson

Download or read book Clinical Bone Marrow and Blood Stem Cell Transplantation written by Kerry Atkinson and published by Cambridge University Press. This book was released on 2004 with total page 2210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drs Richard Champlin, Jerome Ritz, Willem Fibbe, Per Ljungman, and Malcom K. Brenner join Kerry Atkinson as editors of this definitive reference on the clinical practice and underlying science of hematopoietic stem cell transplantation. This third edition text is significantly revised and updated with 124 chapters balancing scientific explanations with practical information on patient care for all aspects of autologous, syngeneic, and allogeneic transplantation. This edition includes 18 new chapters on significant topics such as plasticity of stem cells, embryonic stem cells, and nonmyeloablative conditioning regimens. Thoroughly referenced through 2003, the chapters are divided into 15 sections, including biological background and practical procedures, clinical results, transplant-related and organ-specific complications, laboratory aspects, and developing areas, with a final 'breaking news' chapter from this rapidly evolving field. Over 170 internationally-recognized experts contributed to this authoritative and practical text that is an essential resource for hematologists, oncologists, and transplant specialists.