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Author : James Wilson
Publisher : Springer Science & Business Media
ISBN 13 : 1461589339
Total Pages : 489 pages
Book Rating : 4.4/5 (615 download)
Download or read book Mechanisms and Pathogenesis written by James Wilson and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ronald D. Hood
Publisher : CRC Press
ISBN 13 : 9780849301353
Total Pages : 794 pages
Book Rating : 4.3/5 (13 download)
Download or read book Handbook of Developmental Toxicology written by Ronald D. Hood and published by CRC Press. This book was released on 1996-10-23 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental toxicology, an increasingly important area, encompasses the study of toxicant effects on development, from conception through puberty. The Handbook of Developmental Toxicology provides useful insights gained from hands-on experience, as well as a theoretical foundation. In this convenient reference you will find information not previously gathered in one source-including comparative developmental milestones, historical data, and a glossary of terms used in developmental toxicity evaluation. This handbook is a practical guide for individuals who are responsible for testing chemical agents and for regulatory scientists who must evaluate studies, interpret data, and perform risk assessments. Packed with features, the Handbook of Developmental Toxicology is ideal for training students and technicians in developmental toxicology.
Author : Jürgen Borlak
Publisher : John Wiley & Sons
ISBN 13 : 3527604510
Total Pages : 705 pages
Book Rating : 4.5/5 (276 download)
Download or read book Handbook of Toxicogenomics written by Jürgen Borlak and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicogenomics is a new, dynamic and very promising field that can help optimize toxicity analyses and streamline research into active substances. It is of interest not only for basic research and development, but also from a legal and ethical perspective. Here, experts from all the fields mentioned will find solid information provided by an international team of experienced authors. With its approach as an interdisciplinary overview, it will prove particularly useful for all those needing to develop appropriate research strategies. The authors work for major research institutions, such as the Fraunhofer Institute of Toxicology and Experimental Medicine (Germany), the German Cancer Research Center, the National Institute of Environmental Health Science (USA), the National Institute of Health Science (Japan) or for companies like Affymetrix, Altana Pharma, Bayer, Boehringer Ingelheim, Bruker, Merck, Nimblegen, Novartis, and Syngenta. Coverage ranges from the technology platforms applied, including DNA arrays or proteomics, via the bioinformatics tools required, right up to applications of toxicogenomics presented in numerous case studies, while also including an overview of national programs and initiatives as well as regulatory perspectives. Walter Rosenthal, Director of the Research Institute for Molecular Pharmacology in Berlin, praises the book thus: "I would like to congratulate the publishers of this handbook, one that deals with a extremely hot topic. They have succeeded in gaining as authors leading representatives from this field. The Handbook impressively shows how modern genomic research is leading to rapid advances and new insights within toxicology."
Author : Robert J. Kavlock
Publisher : Springer Science & Business Media
ISBN 13 : 3642604455
Total Pages : 631 pages
Book Rating : 4.6/5 (426 download)
Download or read book Drug Toxicity in Embryonic Development I written by Robert J. Kavlock and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Having received the invitation from Springer-Verlag to produce a volume on drug-induced birth defects for the Handbook of Experimental Pharmacology, we asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this topic to the world's literature. We chose a three-pronged approach, centered around those particular drugs for which we have a relatively well established basis for understanding how they exert their unwanted effects on the human embryo. We then supplemented this information with a series of reviews of critical biological processes involved in the established normal developmental patterns, with emphasis on what happens to the embryo when the processes are perturbed by experimental means. Knowing that the search for mechanisms in teratology has often been inhibited by the lack of understanding of how normal development proceeds, we also included chapters describing the amazing new discoveries related to the molecular control of normal morphogenesis for several organ systems in the hope that the experimental toxicologists and molecular biologists will begin to better appreciate each others questions and progress. Several times during the last two years of developing outlines, issuing invitations, reviewing chapters, and cajoling belated contributors, we have wondered whether we made the correct decision to undertake this effort.
Author : Daniel Bergsma
Publisher : Springer
ISBN 13 : 1349051314
Total Pages : 1214 pages
Book Rating : 4.3/5 (49 download)
Download or read book Birth Defects Compendium written by Daniel Bergsma and published by Springer. This book was released on 2016-06-14 with total page 1214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : James Wilson
Publisher : Springer Science & Business Media
ISBN 13 : 1461589398
Total Pages : 459 pages
Book Rating : 4.4/5 (615 download)
Download or read book Research Procedures and Data Analysis written by James Wilson and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309036879
Total Pages : 476 pages
Book Rating : 4.3/5 (9 download)
Download or read book Drinking Water and Health, written by National Research Council and published by National Academies Press. This book was released on 1986-02-01 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.
Author :
Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.:/5 (49 download)
Download or read book Teratology written by and published by . This book was released on 1992 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publishes original reports of studies in all areas of abnormal development and related fields. It also welcomes reviews of topics of current significance and letters discussing papers that have appeard in Teratology or that deal with controversial scientific matters of interest to its readers.
Author : William J. Rea
Publisher : CRC Press
ISBN 13 : 1439813442
Total Pages : 714 pages
Book Rating : 4.4/5 (398 download)
Download or read book Reversibility of Chronic Disease and Hypersensitivity,Volume 2 written by William J. Rea and published by CRC Press. This book was released on 2014-08-15 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedic in scope, Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 2: The Effects of Environmental Pollutants on the Organ System draws deeply from clinical histories of thousands of patients. It focuses on clinical syndromes within the musculoskeletal, gastrointestinal, and respiratory systems. The book explores mech
Author : E. Grundmann
Publisher : Springer Science & Business Media
ISBN 13 : 3642678610
Total Pages : 387 pages
Book Rating : 4.6/5 (426 download)
Download or read book Drug-Induced Pathology written by E. Grundmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Library of Congress. Copyright Office
Publisher : Copyright Office, Library of Congress
ISBN 13 :
Total Pages : 1666 pages
Book Rating : 4.F/5 ( download)
Download or read book Catalog of Copyright Entries. Third Series written by Library of Congress. Copyright Office and published by Copyright Office, Library of Congress. This book was released on 1978 with total page 1666 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : James Wilson
Publisher : Springer Science & Business Media
ISBN 13 : 1461589363
Total Pages : 336 pages
Book Rating : 4.4/5 (615 download)
Download or read book Comparative, Maternal, and Epidemiologic Aspects written by James Wilson and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modification of embryonic development by genetic differences in the mother is a well-regcognized phemomenon, but little is known about the genet ics of these maternal traits or the mechanisms by which they act. To illustrate the genetic approach to the problem, examples are given of how differences in embryonic response to a teratogen can be partitioned into those resulting from differences in embryonic genotype (including the possible role of X-linked genes in producing reciprocal cross differences), maternal genotype, and cytoplasmically transmitted factors. The advantages and limitations of analysis by appropriate crosses, in utero treatments, embryo transfers, and in vitro experiments are illustrated. The numerous inbred strains of the mouse, with well-documented physiology, the recently developed recombinant inbred strains, and the existence of easily identified biochemical marker genes offer at tractive opportunities, so far largely unexploited, for causal analysis of mater nal effects on teratological responses. VII. ADDENDUM Since this chapter was written, several relevant papers have appeared. The strain difference between AI] and C57BU6] mice in frequency of cleft-palate response to cortisone was fitted to a model of normally distributed log tolerance (Biddle and Fraser, 1976). Genetic differences, both in maternal uterine environment and embryonic response, can be represented in terms of their effect on the median effective dose required for the cleft-palate re sponse. The maternal effect of AI] dams relative to C57BU6] dams caused a two-fold reduction in embryonic tolerance to cortisone-induced cleft palate.
Author : T. V. N. Persaud
Publisher : Alan R. Liss
ISBN 13 :
Total Pages : 204 pages
Book Rating : 4.3/5 (91 download)
Download or read book Basic Concepts in Teratology written by T. V. N. Persaud and published by Alan R. Liss. This book was released on 1985 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William J. Rea
Publisher : CRC Press
ISBN 13 : 9780873719643
Total Pages : 936 pages
Book Rating : 4.7/5 (196 download)
Download or read book Chemical Sensitivity written by William J. Rea and published by CRC Press. This book was released on 1995-11-08 with total page 936 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes that comprise Chemical Sensitivity are the first major scientific books to be published on chemical sensitivity, a growing world-wide health problem. These volumes present clinical experiences in diagnosing and treating chemical sensitivity in over 20,000 patients under controlled conditions.
Author : Russell H. Powell
Publisher : Greenwood
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)
Download or read book Handbooks and Tables in Science and Technology written by Russell H. Powell and published by Greenwood. This book was released on 1983 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eagerly awaited third edition of this important resource provides a listing of over 3,600 scientific and technical handbooks in the hard sciences with over 650 new to this edition. All entries have complete bibliographic citations and most offer brief annotations that describe the content. Serving as both a research and collection development tool, Handbooks and Tables in Science and Technology, was created for users in science and engineering libraries, special and academic libraries, and public libraries with large sci-tech collections. Copyright © Libri GmbH. All rights reserved.
Author : John T. Lett
Publisher : Academic Press
ISBN 13 : 1483281868
Total Pages : 425 pages
Book Rating : 4.4/5 (832 download)
Download or read book Advances in Radiation Biology written by John T. Lett and published by Academic Press. This book was released on 2013-10-22 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Radiation Biology, Volume 12, provides an overview of the state of knowledge in the field of radiation biology. Environmental matters are continuing to produce surprises and remain sources of concern. The safe disposal of radioactive waste still is a major problem facing the nuclear power industry. A possible solution is discussed here. New information about the survivors from radiation exposure at Hiroshima and Nagasaki has emphasized the consequences of brain damage in the developing embryo, the importance of late radiation carcinogenesis, and the roles played by age and sex in human radiation responses. It also is prompting an increasing number of scientists involved in radiation protection to question the use of small animal models to quantify late radiation effects in humans. Contributions to this volume deal with experimental and other aspects of those problems. Finally, increasing confirmation of the dose rate response for densely ionizing radiations has highlighted the hazard they pose to humans in the terrestrial and extraterrestrial environments. Therefore, the intention of agencies in the United States and elsewhere to generate better funded and more scientifically perspicacious programs of space radiation biology is welcome. Possible interests of the military in that regard are also considered.
Author : Brad Bolon
Publisher : CRC Press
ISBN 13 : 1420070096
Total Pages : 446 pages
Book Rating : 4.4/5 (2 download)
Download or read book Pathology of the Developing Mouse written by Brad Bolon and published by CRC Press. This book was released on 2015-04-24 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology expe
