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Guidelines For The Clinical Evaluation Of Drugs Used In The Treatment Of Osteoporosis
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Author :United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products Publisher : ISBN 13 : Total Pages :16 pages Book Rating :4.:/5 (319 download)
Book Synopsis Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis by : United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products
Download or read book Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis written by United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products and published by . This book was released on 1979 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis by :
Download or read book Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis written by and published by . This book was released on 1979 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for Clinical Evaluation of Agents Used in the Treatment Or Prevention of Osteoporosis by : United States. Food and Drug Administration
Download or read book Guidelines for Clinical Evaluation of Agents Used in the Treatment Or Prevention of Osteoporosis written by United States. Food and Drug Administration and published by . This book was released on 1985 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products Publisher : ISBN 13 : Total Pages :20 pages Book Rating :4.:/5 (352 download)
Book Synopsis Guidelines for Preclinical and Clinical Evaluation of Agents Used in the Prevention Or Treatment of Postmenopausal Osteoporosis by : United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products
Download or read book Guidelines for Preclinical and Clinical Evaluation of Agents Used in the Prevention Or Treatment of Postmenopausal Osteoporosis written by United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products and published by . This book was released on 1994 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for Preclinical Evaluation and Clinical Trials in Osteoporosis by : World Health Organization
Download or read book Guidelines for Preclinical Evaluation and Clinical Trials in Osteoporosis written by World Health Organization and published by . This book was released on 1998-01-01 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive guidelines for the design, implementation, and interpretation of preclinical studies and clinical trials of agents undergoing investigation for the management of osteoporosis. Noting the magnitude of the public health problem caused by osteoporosis and related fractures, the book responds to the urgent need for a cohesive and rational approach to the search for new therapeutic or preventive agents. Recommended principles and methods reflect the consensus reached by a large number of international experts, representatives of the pharmaceutical industry, and drug regulatory authorities. The book opens with a brief discussion of the current and future public health problem caused by osteoporotic fractures, followed by conceptual and operational definitions of osteoporosis and a recommended classification of four intervention categories that facilitate the definition of treatment objectives and the design of targetted studies. Against this background, the next chapter offers a detailed guide to the aims, design, conduct and interpretation of preclinical studies. Specific recommendations are given for the selection of in vitro and animal models, the design of the study, including dose ranges and duration of treatment, and the most appropriate end-points for assessing efficacy. The most extensive chapter provides a comprehensive description of basic principles and methods to follow during clinical trials. Information ranges from a discussion of problems with the use of bone mineral density to predict fracture risk, through advice on the choice of tests and techniques for measuring the effects of interventions, to a discussion of general principles of trial design, including selection of study population, treatment regimen, duration of studies, sample size, and frequency of measurement. Drawing on these detailed principles and methods, subsequent chapters offer concise guidance specific to phase I and phase II studies, phase III studies in severe osteoporosis, phase III studies in osteoporosis without fragility fractures, and phase III studies in osteopenia. The book concludes with chapters outlining principles and methods for phase III clinical trials in subjects with normal bone mass, and for phase IV studies.
Book Synopsis Osteoporosis in Men by : Eric S. Orwoll
Download or read book Osteoporosis in Men written by Eric S. Orwoll and published by Academic Press. This book was released on 2009-11-30 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. Brings together more eminent investigators and clinicians to interpret developments in this growing field Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy There is no book on the market that covers osteoporosis in men as comprehensively as this book
Book Synopsis General Considerations for the Clinical Evaluation of Drugs in Infants and Children by : United States. Food and Drug Administration
Download or read book General Considerations for the Clinical Evaluation of Drugs in Infants and Children written by United States. Food and Drug Administration and published by . This book was released on 1977 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Food and Drug Administration. Division of Oncology and Radiopharmaceutical Drug Products Publisher : ISBN 13 : Total Pages :24 pages Book Rating :4.:/5 (318 download)
Book Synopsis Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs by : United States. Food and Drug Administration. Division of Oncology and Radiopharmaceutical Drug Products
Download or read book Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs written by United States. Food and Drug Administration. Division of Oncology and Radiopharmaceutical Drug Products and published by . This book was released on 1981 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs by : United States. Food and Drug Administration. Bureau of Drugs
Download or read book Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs written by United States. Food and Drug Administration. Bureau of Drugs and published by . This book was released on 1981 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for the Clinical Evaluation of Drugs to Prevent, Control and by : United States. Food and Drug Administration
Download or read book Guidelines for the Clinical Evaluation of Drugs to Prevent, Control and written by United States. Food and Drug Administration and published by . This book was released on 1978 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for the Clinical Evaluation of Antineoplastic Drugs by :
Download or read book Guidelines for the Clinical Evaluation of Antineoplastic Drugs written by and published by . This book was released on 1981 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Food and Drug Administration. Division of Neuropharmacological Drug Products Publisher : ISBN 13 : Total Pages :20 pages Book Rating :4.:/5 (318 download)
Book Synopsis Guidelines for the Clinical Evaluation of Antiepileptic Drugs (adults and Children). by : United States. Food and Drug Administration. Division of Neuropharmacological Drug Products
Download or read book Guidelines for the Clinical Evaluation of Antiepileptic Drugs (adults and Children). written by United States. Food and Drug Administration. Division of Neuropharmacological Drug Products and published by . This book was released on 1981 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products Publisher : ISBN 13 : Total Pages :20 pages Book Rating :4.:/5 (319 download)
Book Synopsis Guidelines for the Clinical Evaluation of Lipid-altering Agents in Adults and Children by : United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products
Download or read book Guidelines for the Clinical Evaluation of Lipid-altering Agents in Adults and Children written by United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products and published by . This book was released on 1980 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Andrea Giustina Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805572964 Total Pages :213 pages Book Rating :4.8/5 (55 download)
Book Synopsis Glucocorticoid-induced Osteoporosis by : Andrea Giustina
Download or read book Glucocorticoid-induced Osteoporosis written by Andrea Giustina and published by Karger Medical and Scientific Publishers. This book was released on 2002 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis is one of the most clinically relevant disabling chronic disease encountered in clinical practice. A common cause of osteoporosis is glucocorticoid excess, as glucocorticoids may increase bone resorption, inhibit bone formation, have indirect actions on bone by decreasing intestinal calcium absorption and induce hypercalciuria. This book presents a comprehensive overview of the effects of glucocorticoids on bone metabolism and structure and on the diagnosis and treatment of glucocorticoid-induced osteoporosis. It aims at providing updated information on the pathogenesis, diagnosis and treatment of this often dramatic complication of glucocorticoid excess. Being one of the few publications completely devoted to glucocorticoid-induced osteoporosis it will heighten the awareness of specialists who prescribe glucocorticoids of the clinical relevance of this treatment complication. 'Glucocorticoid-Induced Osteoporosis' is addressed to clinical experts as well as to general practitioners who will both benefit from the comprehensive and integrative view of the management of patients exposed to glucocorticoids.
Download or read book Osteoporosis written by and published by . This book was released on 2012 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are a number of therapies and treatments available for the prevention of fragility fractures in people thought to be at risk, or to prevent further fractures in those who have already had one or more fragility fractures. However, identifying who will benefit from preventative treatment is imprecise. A number of risk assessment tools are available to predict fracture incidence over a period of time, and these may be used to aid decision making. These tools are limited in that they may not include all risk factors, or may lack details of some risk factors. Tools are dependent on the accuracy of the epidemiological data used to derive them and tools validated in other populations may not apply to the UK. Two tools, FRAX and QFracture, are available for use in the UK. It is not clear whether these tools are equally accurate and whether choice of tool should depend on circumstances. This short clinical guideline aims to provide guidance on the selection and use of risk assessment tools in the care of people who may be at risk of fragility fractures in all settings in which NHS care is received.
Book Synopsis Clinical Gynecology by : Eric J. Bieber
Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.
Book Synopsis Chalk Talks in Internal Medicine by : Somnath Mookherjee
Download or read book Chalk Talks in Internal Medicine written by Somnath Mookherjee and published by Springer Nature. This book was released on 2020-09-30 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides teaching scripts for medical educators in internal medicine and coaches them in creating their own teaching scripts. Every year, thousands of attending internists are asked to train the next generation of physicians to master a growing body of knowledge. Formal teaching time has become increasingly limited due to rising clinical workload, medical documentation requirements, duty hour restrictions, and other time pressures. In addition, today’s physicians-in-training expect teaching sessions that deliver focused, evidence-based content that is integrated into clinical workflow. In keeping with both time pressures and trainee expectations, academic internists must be prepared to effectively and efficiently teach important diagnostic and management concepts. A teaching script is a methodical and structured plan that aids in effective teaching. The teaching scripts in this book anticipate learners’ misconceptions, highlight a limited number of teaching points, provide evidence to support the teaching points, use strategies to engage the learners, and provide a cognitive scaffold for teaching the topic that the teacher can refine over time. All divisions of internal medicine (e.g. cardiology, rheumatology, and gastroenterology) are covered and a section on undifferentiated symptom-based presentations (e.g. fatigue, fever, and unintentional weight loss) is included. This book provides well-constructed teaching scripts for commonly encountered clinical scenarios, is authored by experienced academic internists and allows the reader to either implement them directly or modify them for their own use. Each teaching script is designed to be taught in 10-15 minutes, but can be easily adjusted by the reader for longer or shorter talks. Teaching Scripts in Internal Medicine is an ideal tool for internal medicine attending physicians and trainees, as well as physician’s assistants, nurse practitioners, and all others who teach and learn internal medicine.
