GnRH: The Master Molecule of Reproduction

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1475735650
Total Pages : 338 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis GnRH: The Master Molecule of Reproduction by : Andrea C. Gore

Download or read book GnRH: The Master Molecule of Reproduction written by Andrea C. Gore and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of neurons in rostral hypothalamic regions of the brain. In mammals, these neurons release the GnRH decapeptide into the portal capillary system leading to the anterior pituitary gland. There, GnRH causes the release of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn act upon the gonads to stimulate their maturation, and to cause synthesis of sex steroid hormones, estrogen, progesterone and testosterone. Although each of the levels of the hypothalamic-pituitary-gonadal axis is critical for reproductive function, GnRH neurons play the primary role in the control of reproductive maturation and adult reproductive function, and may even play a role in reproductive senescence. Since its discovery in 1970, there has been intense interest in GnRH-producing neurons, with more than 8000 papers and chapters in the last decade alone. Despite this activity of research in basic and clinical science, there has never been a book written specifically on GnRH neurons. GnRH: The Master Molecule of Reproduction aims to bring together the large and diverse literature of both laboratory and applied research that focuses on these unique cells. This book will provide basic background into reproductive neuroendocrinology, as well as specifics regarding the role of GnRH neurons in the control of reproduction. Students studying endocrinology, reproduction, neuroendocrinology or molecular endocrinology will benefit from this book. In addition, this book will take a multi-species approach which will be useful both to basic researchers as well as clinicians. Whenever possible, species differences and similarities will be presented, and if possible, studies on humans, or the clinical relevance of basic research findings to humans will be discussed (such as the treatment of reproductive disorders such as abnormalities in pubertal development, or infertility).

Gonadotropin-Releasing Hormone: Molecules and Receptors

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Author :
Publisher : Elsevier
ISBN 13 : 0080524761
Total Pages : 345 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Gonadotropin-Releasing Hormone: Molecules and Receptors by : I.S. Parhar

Download or read book Gonadotropin-Releasing Hormone: Molecules and Receptors written by I.S. Parhar and published by Elsevier. This book was released on 2002-11-22 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes the evolution and physiology of GnRH molecules and receptors, and provides insight as to how social behavior influences cellular and molecular events in the brain from a comparative perspective.The chapters in this volume are divided into three major sections: Development and Cell Migration, GnRH Receptors, Physiology and Regulation. The review papers arose primarily from presentations made at the Second International Symposium on the Comparative Biology of GnRH, held in Penang, Malaysia, June 2-4, 2001; a satellite symposium in conjunction with the XIV International Congress of Comparative Endocrinology, Sorrento, Italy. In addition, leading neuroscientists doing cutting-edge research in the field of GnRH were invited as authors to make this volume a valuable reference.

Encyclopedia of Neuroscience, Volume 1

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Publisher : Academic Press
ISBN 13 : 0080963935
Total Pages : 12505 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Encyclopedia of Neuroscience, Volume 1 by : Larry R. Squire

Download or read book Encyclopedia of Neuroscience, Volume 1 written by Larry R. Squire and published by Academic Press. This book was released on 2009-06-12 with total page 12505 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.

Reproductive Technologies and Biobanking for the Conservation of Amphibians

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Author :
Publisher : CSIRO PUBLISHING
ISBN 13 : 1486313345
Total Pages : 249 pages
Book Rating : 4.4/5 (863 download)

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Book Synopsis Reproductive Technologies and Biobanking for the Conservation of Amphibians by : Andy J. Kouba

Download or read book Reproductive Technologies and Biobanking for the Conservation of Amphibians written by Andy J. Kouba and published by CSIRO PUBLISHING. This book was released on 2022-10-03 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to decelerate loss of global biodiversity is one of the greatest challenges of our generation. Reproductive technologies have enormous potential to assist the recovery of species by enhancing reproductive output, facilitating genetic management, and supporting reintroduction of threatened species. Of particular value are cryopreservation technologies coupled with the establishment of global gene banks to conserve, in perpetuity, the remaining extant genetic diversity of threatened amphibians. Reproductive Technologies and Biobanking for the Conservation of Amphibians brings together leading experts in the field to provide a comprehensive overview of current best practices, summarise technological advancements, and present a framework for facilitating the integration of reproductive technologies and biobanking into conservation breeding programs for threatened amphibians. It is an invaluable reference for the next generation of conservation practitioners: captive breeding facilities, researchers, and policy-makers involved with biodiversity conservation.

The GnRH Neuron and its Control

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Publisher : John Wiley & Sons
ISBN 13 : 1119233291
Total Pages : 683 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis The GnRH Neuron and its Control by : Allan E. Herbison

Download or read book The GnRH Neuron and its Control written by Allan E. Herbison and published by John Wiley & Sons. This book was released on 2018-03-02 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: The GnRH Neuron and its Control examines the developmental biology of GnRH neurons including their birth in the nasal placode of the early embryo, perinatal programming, and sexual differentiation, in addition to the hypothalamic mechanisms that control GnRH neurons in adulthood to generate pulsatile and surge modes of GnRH secretion throughout the major life stages including aging. The morphology, electrophysiology, signal transduction pathways, transcriptional regulators, and genomics underlying function of the adult GnRH neuron is discussed in detail, as is the neuroendocrinology and cell biology governing the generation of both modes of GnRH release. The book also reviews the neurobiological mechanisms and circuitry responsible for the modulation of the activity of GnRH neurons by season, stress, nutrition, and metabolism, and covers the current and potential therapeutic approaches to regulating GnRH secretion and action. Filled with newly identified research and classical fundamental knowledge to GnRH biology, it will provide students, researchers, and practitioners with an in-depth understanding of reproductive neuroendocrinology. This is the fifth volume in the Masterclass in Neuroendocrinology Series, a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

DeGroot's Endocrinology, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323694136
Total Pages : 2539 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis DeGroot's Endocrinology, E-Book by : R. Paul Robertson

Download or read book DeGroot's Endocrinology, E-Book written by R. Paul Robertson and published by Elsevier Health Sciences. This book was released on 2022-09-29 with total page 2539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology, DeGroot’s Endocrinology, 8th Edition, remains the comprehensive, international reference of choice for today’s endocrinologists and fellows. A full peer review of the previous edition, conducted by a largely new group of renowned editors, was used to update this trusted, two-volume resource. In-depth coverage of both basic and clinical aspects of endocrinology and up-to-date information on the treatment and management of endocrine disorders are provided by a diverse group of expert contributors from six continents. A full-color format and helpful algorithms summarize clinical decision-making and practical approaches to patient management. Organizes content by all the glands that regulate the endocrine system while integrating basic science and clinical presentations of disease. Includes new chapters: Anatomy and Physiology of the Hypothalmus and Pituitary, Differentiated Thyroid Cancer, Medullary Thyroid Cancer, Drugs that Affect Thyroid Function, Genetic Disorders of the Adrenal Cortex, Adrenal Pathology, Primary Aldosteronism, Transgender Healthcare, Erectile Dysfunction, Prevalence and Causes of Male Infertility, Sexual Dysfunction in the Female, Glucose Toxicity and Oxidative Stress. Emphasizes basic science and evidence-based practice throughout. Features extensive updates to content on thyroid and adrenal disfunction, endocrine-disrupting chemicals and human disease, clinical management of diabetes, and advances in genetics. Includes algorithms to outline effective treatment protocols. Contains new emphasis boxes that highlight key points in each chapter.

Handbook of Models for Human Aging

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Author :
Publisher : Elsevier
ISBN 13 : 0080460062
Total Pages : 1103 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Models for Human Aging by : P. Michael Conn

Download or read book Handbook of Models for Human Aging written by P. Michael Conn and published by Elsevier. This book was released on 2011-04-28 with total page 1103 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. - Utilizes a multidisciplinary approach - Shows tricks and approaches not available in primary publications - First volume of its kind to combine both methods of study for human aging and animal models - Over 200 illustrations

Hormones, Brain and Behavior Online

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Author :
Publisher : Academic Press
ISBN 13 : 008088783X
Total Pages : 5944 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Hormones, Brain and Behavior Online by :

Download or read book Hormones, Brain and Behavior Online written by and published by Academic Press. This book was released on 2002-06-18 with total page 5944 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones, Brain, and Behavior, Second Edition is a comprehensive work discussing the effect of hormones on the brain and, subsequently, behavior. This major reference work has 109 chapters covering a broad range of topics with an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. To truly understand all aspects of our behavior, we must take every influence (including the hormonal influences) into consideration. Donald Pfaff and a number of well-qualified editors examine and discuss how we are influenced by hormonal factors, offering insight, and information on the lives of a variety of species. Hormones, Brain, and Behavior offers the reader comprehensive coverage of growing field of research, with a state-of-the-art overview of hormonally-mediated behaviors. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Available online exclusively via ScienceDirect. A limited edition print version is also available. Comprehensive coverage of a growing field of research Unique treatment of all major vertebrate and invertebrate model systems with excellent opportunites for relating behavior to molecular genetics Covers an unusual breadth ranging from molecules to ecophysiology, and from basic science to clinical research

Teaching Tomorrow's Medicine Today

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Publisher : NYU Press
ISBN 13 : 0814758762
Total Pages : 638 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Teaching Tomorrow's Medicine Today by : Barbara Niss

Download or read book Teaching Tomorrow's Medicine Today written by Barbara Niss and published by NYU Press. This book was released on 2005-02-01 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: From Mount Sinai Department of Surgery chairman Arthur H. Afuses, Jr. and archivist Barbara Nuss, an instructional account of Mount Sinai's teaching methods The Mount Sinai Hospital was founded in 1852 as the Jews’ Hospital in the City of New York, but more than a century would pass before a school of medicine was created at Mount Sinai. In Teaching Tomorrow’s Medicine Today, Arthur H. Aufses, Jr., chairman of Mount Sinai's Department of Surgery, and archivist Barbara Niss chronicle the development of the medical school from its origins in the 1960s to the current leadership. The authors examine the social forces that compelled the world-renowned hospital to remake itself as an academic medical center, revealing the school's departure from and subsequent return to its founders' original vision. In addition to a compelling history of each of Mount Sinai’s departments, Teaching Tomorrow’s Medicine Today describes the school’s methods for providing both graduate or resident training and post-graduate physician education. Recognizing Mount Sinai’s central mission as a teaching institution, the authors close their account with perspectives of alumni and current students.

On Rheostasis

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Publisher : Oxford University Press
ISBN 13 : 0197665578
Total Pages : 225 pages
Book Rating : 4.1/5 (976 download)

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Book Synopsis On Rheostasis by : Tyler John Stevenson

Download or read book On Rheostasis written by Tyler John Stevenson and published by Oxford University Press. This book was released on 2024-01-09 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: On Rheostasis describes several examples of physiological changes most species of animals will experience in their lifetime, such as daily rhythms, reproductive cycles, and infection induced fevers. These naturally occurring events are a major challenge to the basic understanding of how bodies maintain a healthy, internal working environment. The book uses new research to highlight that our internal state is regulated by different physiological processes.

The Psychoses of Menstruation and Childbearing

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Publisher : Cambridge University Press
ISBN 13 : 1107113601
Total Pages : 407 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis The Psychoses of Menstruation and Childbearing by : Ian Brockington

Download or read book The Psychoses of Menstruation and Childbearing written by Ian Brockington and published by Cambridge University Press. This book was released on 2017-08-11 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the range of psychoses that complicate the reproductive process, describing a range of interventions and preventive strategies.

Neuroendocrinology of Reproduction

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468438816
Total Pages : 571 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Neuroendocrinology of Reproduction by : Norman T. Adler

Download or read book Neuroendocrinology of Reproduction written by Norman T. Adler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of this book is neuroendocrinology, that branch of biological science devoted to the interactions between the two major integrative organ systems of animals-the endocrine and nervous systems. Although this science today reflects a fusion of endocrinology and neurobiology, this synthetic ap proach is relatively recent. At the beginning of the 20th century, when the British physiologists, Bayliss and Starling, first proposed endocrinology to be an independent field of inquiry, they went to great lengths to establish the autonomy of chemical secretions in general and their independence from nervous control in particular (Bayliss, W. M. , and Starling, E. H. , 1902, The mechanism of pancreatic secretion,]. Physiol. 28:325). They argued with Pav lov, who said that there was a strong influence of the nervous system on the gastrointestinal phenomena the endocrinologists were studying. For several decades, the English physiologists prevailed, at least in the West; and Pavlov's critique was not taken to heart by the practitioners of the newly emerging discipline of endocrinology. Through the work of Harris, the Scharrers, Sawyer, Everett, and others, there has been something of a scientific detente in the latter half of this century; the hybrid field of neuroendocrinology is now regarded as one of the corner stones of modern neural science and is of fundamental importance in basic and clinical endocrinology.

The Clinical Chemistry of Laboratory Animals

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Publisher : CRC Press
ISBN 13 : 1351643096
Total Pages : 1685 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis The Clinical Chemistry of Laboratory Animals by : David M. Kurtz

Download or read book The Clinical Chemistry of Laboratory Animals written by David M. Kurtz and published by CRC Press. This book was released on 2017-10-18 with total page 1685 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key features: Serves as the detailed, authoritative source of the clinical chemistry of the most commonly used laboratory animals Includes detailed chapters dedicated to descriptions of clinical chemistry-related topics specific to each laboratory species as well as organ/class-specific chapters Presents information regarding evaluation and interpretation of a variety of individual clinical chemistry end points Concludes with detailed chapters dedicated to descriptions of statistical analyses and biomarker development of clinical chemistry-related topics Provides extensive reference lists at the end of each chapter to facilitate further study Extensively updated and expanded since the publication of Walter F. Loeb and Fred W. Quimby’s second edition in 1999, the new The Clinical Chemistry of Laboratory Animals, Third Edition continues as the most comprehensive reference on in vivo animal studies. By organizing the book into species- and organ/class-specific chapters, this book provides information to enable a conceptual understanding of clinical chemistry across laboratory species as well as information on evaluation and interpretation of clinical chemistry data relevant to specific organ systems. Now sponsored by the American College of Laboratory Animal Medicine (ACLAM), this well-respected resource includes chapters on multiple laboratory species and provides pertinent information on their unique physiological characteristics, methods for sample collection, and preanalytical sources of variation for the particular species. Basic methodology for common procedures for each species is also discussed. New Chapters in the Third Edition Include: The Laboratory Zebrafish and Other Fishes Evaluation of Cardiovascular and Pulmonary Function and Injury Evaluation of Skeletal Muscle Function and Injury Evaluation of Bone Function and Injury Vitamins Development of Biomarkers Statistical Methods The Clinical Chemistry of Laboratory Animals, Third Edition is intended as a reference for use by veterinary students, clinical veterinarians, verterinary toxicologists, veterinary clinical pathologists, and laboratory animal veterinarians to aid in study design, collection of samples, and interpretation of clinical chemistry data for laboratory species.

Pollution and Fish Health in Tropical Ecosystems

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Author :
Publisher : CRC Press
ISBN 13 : 1482212897
Total Pages : 402 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Pollution and Fish Health in Tropical Ecosystems by : Eduardo Alves de Almeida

Download or read book Pollution and Fish Health in Tropical Ecosystems written by Eduardo Alves de Almeida and published by CRC Press. This book was released on 2016-04-19 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tropical zone contains the highest diversity of fish species on the planet. Many of these species are being continuously exposed to pollutants that pose serious hazards to fish health thereby posing serious risks for entire fish populations. This book presents information about the different responses of fish to pollutants from the molecular le

Endocrine Disruptors and the Developing Brain

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Author :
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615040870
Total Pages : 115 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Endocrine Disruptors and the Developing Brain by : Andrea C. Gore

Download or read book Endocrine Disruptors and the Developing Brain written by Andrea C. Gore and published by Morgan & Claypool Publishers. This book was released on 2012 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of endocrine disruption has been the focus of increasing attention from scientists and the general public in the past 30 years, amidst concerns that exposure to environmental chemicals with the potential to alter endocrine system function, known as endocrine disrupting chemicals (EDCs), may be contributing to an overall decline in wildlife populations and the reproductive health of humans. These concerns are based on observations of adverse effects of EDCs on marine and land animals, an increased incidence of reproductive and endocrine disease in humans, epidemiological evidence for links between body burden and disease, and endocrine disruption in laboratory animals following exposure to EDCs. Owing to its role in regulation of endocrine function as well as its responsiveness to hormones, the developing brain is an especially vulnerable target for many classes of EDCs. This book will address the evidence for EDC action on the developing brain, organized into 7 chapters. Topics covered include background about EDCs, evidence for exposures, concerns about EDC effects in the developing organism, and particularly on the developing nervous system, how EDCs perturb the brain's neuroendocrine systems, transgenerational epigenetic effects of EDCs, EDC effects on non-reproductive behaviors, and future perspectives. This is the first book completely dedicated to understanding links between EDCs and the developing brain, an area of emerging importance for human health. Table of Contents: What Are Environmental Endocrine-Disrupting Chemicals (EDCs)? / EDC Exposures / EDCs and Development / EDCs and the Developing Brain / EDCs and Neuroendocrine Systems / Epigenetic Effects of EDCs / EDCs, the Brain, and the Future / Acknowledgments / References / Author Biographies

Sex Steroids

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 953307857X
Total Pages : 346 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Sex Steroids by : Scott M. Kahn

Download or read book Sex Steroids written by Scott M. Kahn and published by BoD – Books on Demand. This book was released on 2012-01-27 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, entitled "Sex Steroids", features a valuable collection of reviews and research articles written by experts in signal transduction, cellular biology, diseases and disorders. "Sex Steroids" is comprised of four sections, "The Biology of Sex Steroids", "Sex Steroids, Memory, and the Brain", "Sex Steroids and the Immune Response", and "Therapy"; individual chapters address a broad range of recognized and predicted functions and applications of sex steroids. "Sex Steroids" is intended to provide seasoned veterans as well as newcomers to this area of research with informative, resourceful, and provocative insights. Readers of "Sex Steroids" should emerge with an appreciation and understanding of the multitude and complexity of biologic processes attributed to these important hormones, and possible future directions of research in this fascinating and ever evolving field.

Fundamental Neuroscience

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Publisher : Academic Press
ISBN 13 : 0123858704
Total Pages : 1154 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Fundamental Neuroscience by : Larry Squire

Download or read book Fundamental Neuroscience written by Larry Squire and published by Academic Press. This book was released on 2013 with total page 1154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive textbook seeks to define the full scope of neuroscience. Developed in accordance with results of extensive reviews, the text is divided into seven integrated sections.