Global Progress Toward Measles Eradication and Prevention of Rubella and Congenital Rubella Syndrome
Author : Stephen L. Cochi
Publisher :
ISBN 13 :
Total Pages : 569 pages
Book Rating : 4.:/5 (753 download)
Book Synopsis Global Progress Toward Measles Eradication and Prevention of Rubella and Congenital Rubella Syndrome by : Stephen L. Cochi
Download or read book Global Progress Toward Measles Eradication and Prevention of Rubella and Congenital Rubella Syndrome written by Stephen L. Cochi and published by . This book was released on 2011 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In this supplement, the papers have been organized under 6 topic headings. The first of these, 'Public Health Importance of Measles and Rubella, describes the global burden of disease due to measles and rubella and the tremendous impact on this disease burden during the vaccine era through the application of appropriate vaccination strategies, while noting the remaining unfinished agenda to complete the interruption of transmission of these diseases and their devastating effects. In the case of measles, documentation is provided of the major contribution of measles vaccination since 1990 toward reducing deaths among children aged 5 years worldwide. The next section, 'Feasibility of Measles Eradication, presents the results of various studies requested in 2008 by the Member States of the WHO to assess the feasibility of measles eradication. These studies include evaluation of the biological, technical, and operational feasibility of measles eradication; a comparative analysis of measles eradication with other previous and current eradication initiatives; issues related to availability of a sufficient global vaccine supply; and assessment of the impact of such an initiative on immunization services and health systems. The third section, 'Economic Studies, ' provides economic analyses at the country and global levels of the costeffectiveness and cost-benefit of measles eradication. These studies demonstrate that measles eradication is highly costeffective regardless of country income level, is cost-saving in those countries that have already eliminated measles, and compares favorably with almost any other investment in health. The fourth section, 'Measles Vaccine Safety and Effectiveness, ' reviews and highlights studies of the field effectiveness of measles-containing vaccines, persistence of measles antibodies following vaccination, the relative contributions of the first and second routine doses of measles vaccine and measles mass campaign doses to the observed public health impact of measles vaccination, the safety and immunogenicity of measles vaccination in human immunodeficiency virus-infected children, and progress toward improving injection safety in Africa catalyzed by the Measles Initiative. The fifth section, 'Regional and Country Experiences, ' offers a collection of country and regional reports on the epidemiology of measles and rubella, as well as articles about the progress towards achieving regional measles mortality reduction and elimination targets. The epidemiology of recent outbreaks of measles is described in detail. Issues regarding the programmatic and operational feasibility are addressed, and the successful experience and lessons learned in the Americas are highlighted. The final section of the supplement, 'Molecular Epidemiology and Laboratory Aspects of Measles and Rubella Surveillance, provides an overview of the expansion of the WHO Global Measles and Rubella Laboratory Network, with emphasis on advances in molecular epidemiology of measles and rubella, new testing procedures, and the challenges associated with laboratory testing in an elimination setting."--Page S2-S3.
