RNA Exosome

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Publisher : Springer Science & Business Media
ISBN 13 : 1441978410
Total Pages : 161 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis RNA Exosome by : Torben Heick Jensen

Download or read book RNA Exosome written by Torben Heick Jensen and published by Springer Science & Business Media. This book was released on 2011-06-29 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.

The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation

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Publisher : Bentham Science Publishers
ISBN 13 : 1608054926
Total Pages : 225 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation by : Kenneth Berendzen

Download or read book The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation written by Kenneth Berendzen and published by Bentham Science Publishers. This book was released on 2013-10-29 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major goal of integrative research is understanding regulatory networks to such an extent as to allow researchers to model developmental and stress responses. Regulatory networks of living systems include complex and vast interactions between proteins, metabolites, RNA, various signaling molecules and DNA. One aspect of systems biology is understanding the dynamics of protein-DNA interactions affecting gene expression that are caused by transcription factors (TFs) and chromatin remodeling factors. This e-book provides a resource for summarizing current knowledge eukaryotic transcription and explores cis-elements and methods for their analysis, prediction and discovery. The book also presents an overview of exploring gene regulatory networks, chromatin, and miRNAs. Information about state-of-the-art techniques for the determination of TF - cis-element interactions in vivo and in silico give cutting edge insights on how genomic-scale research is being approached. The Analysis of Regulatory DNA provides readers with both the necessary background knowledge and provocative, up-to-date insights aimed at sparking new and vibrant experimental designs for understanding and predicting cis-elements in the eukaryotic genome.

Comparative Physiology of Fasting, Starvation, and Food Limitation

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Publisher : Springer Science & Business Media
ISBN 13 : 3642290566
Total Pages : 431 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Comparative Physiology of Fasting, Starvation, and Food Limitation by : Marshall D. McCue

Download or read book Comparative Physiology of Fasting, Starvation, and Food Limitation written by Marshall D. McCue and published by Springer Science & Business Media. This book was released on 2012-05-17 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: All animals face the possibility of food limitation and ultimately starvation-induced mortality. This book summarizes state of the art of starvation biology from the ecological causes of food limitation to the physiological and evolutionary consequences of prolonged fasting. It is written for an audience with an understanding of general principles in animal physiology, yet offers a level of analysis and interpretation that will engage seasoned scientists. Each chapter is written by active researchers in the field of comparative physiology and draws on the primary literature of starvation both in nature and the laboratory. The chapters are organized among broad taxonomic categories, such as protists, arthropods, fishes, reptiles, birds, and flying, aquatic, and terrestrial mammals including humans; particularly well-studied animal models, e.g. endotherms are further organized by experimental approaches, such as analyses of blood metabolites, stable isotopes, thermobiology, and modeling of body composition.

Plant Comparative Genomics

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Publisher : Springer Nature
ISBN 13 : 1071624296
Total Pages : 293 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Plant Comparative Genomics by : Alejandro Pereira-Santana

Download or read book Plant Comparative Genomics written by Alejandro Pereira-Santana and published by Springer Nature. This book was released on 2022-07-11 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book presents recent methodologies for the task of inspecting the genomic world of plants, extracting valuable information, and presenting it in a readable way. With a focus on bioinformatics tools, the volume explores phylogenetics and evolution, Omics analysis, as well as experimental procedures for trait characterization. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of vital expert implementation advice that will lead to successful results. Authoritative and practical, Plant Comparative Genomics serves as an ideal resource for researchers looking to implement comparative tools in order to explore their genomic data for their daily scientific work.

Advances in Drosophila Research and Application: 2012 Edition

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Publisher : ScholarlyEditions
ISBN 13 : 1464998558
Total Pages : 183 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Advances in Drosophila Research and Application: 2012 Edition by :

Download or read book Advances in Drosophila Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Drosophila Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Drosophila. The editors have built Advances in Drosophila Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Drosophila in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Drosophila Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Emerging Research in the Analysis and Modeling of Gene Regulatory Networks

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Publisher : IGI Global
ISBN 13 : 1522503544
Total Pages : 437 pages
Book Rating : 4.5/5 (225 download)

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Book Synopsis Emerging Research in the Analysis and Modeling of Gene Regulatory Networks by : Ivanov, Ivan V.

Download or read book Emerging Research in the Analysis and Modeling of Gene Regulatory Networks written by Ivanov, Ivan V. and published by IGI Global. This book was released on 2016-06-06 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: While technological advancements have been critical in allowing researchers to obtain more and better quality data about cellular processes and signals, the design and practical application of computational models of genomic regulation continues to be a challenge. Emerging Research in the Analysis and Modeling of Gene Regulatory Networks presents a compilation of recent and emerging research topics addressing the design and use of technology in the study and simulation of genomic regulation. Exploring both theoretical and practical topics, this publication is an essential reference source for students, professionals, and researchers working in the fields of genomics, molecular biology, bioinformatics, and drug development.

Long-Range Control of Gene Expression

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Publisher : Academic Press
ISBN 13 : 0080877818
Total Pages : 415 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Long-Range Control of Gene Expression by : Veronica van Heyningen

Download or read book Long-Range Control of Gene Expression written by Veronica van Heyningen and published by Academic Press. This book was released on 2011-09-02 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. Discusses the evolution of cis-regulatory sequences in drosophila Includes information on genomic imprinting and imprinting defects in humans Includes a chapter on epigenetic gene regulation in cancer

Genomic Regulatory Systems

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Publisher : Elsevier
ISBN 13 : 0080525598
Total Pages : 274 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Genomic Regulatory Systems by : Eric H. Davidson

Download or read book Genomic Regulatory Systems written by Eric H. Davidson and published by Elsevier. This book was released on 2001-01-24 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interaction between biology and evolution has been the subject of great interest in recent years. Because evolution is such a highly debated topic, a biologically oriented discussion will appeal not only to scientists and biologists but also to the interested lay person. This topic will always be a subject of controversy and therefore any breaking information regarding it is of great interest.The author is a recognized expert in the field of developmental biology and has been instrumental in elucidating the relationship between biology and evolution. The study of evolution is of interest to many different kinds of people and Genomic Regulatory Systems: In Development and Evolution is written at a level that is very easy to read and understand even for the nonscientist.* Contents Include* Regulatory Hardwiring: A Brief Overview of the Genomic Control Apparatus and Its Causal Role in Development and Evolution * Inside the Cis-Regulatory Module: Control Logic and How the Regulatory Environment Is Transduced into Spatial Patterns of Gene Expression* Regulation of Direct Cell-Type Specification in Early Development* The Secret of the Bilaterians: Abstract Regulatory Design in Building Adult Body Parts* Changes That Make New Forms: Gene Regulatory Systems and the Evolution of Body Plans

Drosophila

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Publisher : Springer Nature
ISBN 13 : 1071625411
Total Pages : 423 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Drosophila by : Christian Dahmann

Download or read book Drosophila written by Christian Dahmann and published by Springer Nature. This book was released on 2022-08-18 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and cell lineage tracing, protein inhibition and tagging, optogenetic and optochemical control of tissue mechanics, AFM measurements, sample preparation for electron microscopy, live imaging of different tissues and organs, and quantitative image analysis. Written in the format of the highly successful Methods in Molecular Biology series, chapters include an introduction to their topic, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls Authoritative and cutting-edge, Drosophila: Methods and Protocols, Third Edition serves as a useful and practical guide to new researchers and experts using Drosophila as a model system. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Selected Works of Peter J. Bickel

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Publisher : Springer Science & Business Media
ISBN 13 : 1461455448
Total Pages : 626 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Selected Works of Peter J. Bickel by : Jianqing Fan

Download or read book Selected Works of Peter J. Bickel written by Jianqing Fan and published by Springer Science & Business Media. This book was released on 2012-11-28 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents selections of Peter J. Bickel’s major papers, along with comments on their novelty and impact on the subsequent development of statistics as a discipline. Each of the eight parts concerns a particular area of research and provides new commentary by experts in the area. The parts range from Rank-Based Nonparametrics to Function Estimation and Bootstrap Resampling. Peter’s amazing career encompasses the majority of statistical developments in the last half-century or about about half of the entire history of the systematic development of statistics. This volume shares insights on these exciting statistical developments with future generations of statisticians. The compilation of supporting material about Peter’s life and work help readers understand the environment under which his research was conducted. The material will also inspire readers in their own research-based pursuits. This volume includes new photos of Peter Bickel, his biography, publication list, and a list of his students. These give the reader a more complete picture of Peter Bickel as a teacher, a friend, a colleague, and a family man.

The Regulatory Genome

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Publisher : Elsevier
ISBN 13 : 0080455573
Total Pages : 303 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Regulatory Genome by : Eric H. Davidson

Download or read book The Regulatory Genome written by Eric H. Davidson and published by Elsevier. This book was released on 2010-07-19 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. - The only book in the market that is solely devoted to the genomic regulatory code for animal development - Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding - Presents a comprehensive treatment of molecular control elements that determine the function of genes - Provides a comparative treatment of development, based on principles rather than description of developmental processes - Considers the evolutionary processes in terms of the structural properties of gene regulatory networks - Includes 42 full-color descriptive figures and diagrams

Epigenetics and Systems Biology

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Publisher : Academic Press
ISBN 13 : 0128030763
Total Pages : 287 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Epigenetics and Systems Biology by : Leonie Ringrose

Download or read book Epigenetics and Systems Biology written by Leonie Ringrose and published by Academic Press. This book was released on 2017-04-25 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics and Systems Biology highlights the need for collaboration between experiments and theoretical modeling that is required for successful application of systems biology in epigenetics studies. This book breaks down the obstacles which exist between systems biology and epigenetics researchers due to information barriers and segmented research, giving real-life examples of successful combinations of systems biology and epigenetics experiments. Each section covers one type of modeling and one set of epigenetic questions on which said models have been successfully applied. In addition, the book highlights how modeling and systems biology relate to studies of RNA, DNA, and genome instability, mechanisms of DNA damage signaling and repair, and the effect of the environment on genome stability. - Presents original research in a wider perspective to reveal potential for synergies between the two fields of study - Provides the latest experiments in primary literature for the modeling audience - Includes chapters written by experts in systems biology and epigenetics who have vast experience studying clinical applications

Statistical Population Genomics

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Publisher :
ISBN 13 : 9781013271403
Total Pages : 464 pages
Book Rating : 4.2/5 (714 download)

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Book Synopsis Statistical Population Genomics by : Julien Y Dutheil

Download or read book Statistical Population Genomics written by Julien Y Dutheil and published by . This book was released on 2020-10-08 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Insect Life Cycles

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Publisher : Springer Science & Business Media
ISBN 13 : 1447134648
Total Pages : 256 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Insect Life Cycles by : Francis Gilbert

Download or read book Insect Life Cycles written by Francis Gilbert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: No International Congress of Entomology would now be complete without a symposium on insect life-cycles. The latest Congress, held at Vancouver, BC (Canada), in July 1988, was no exception, with a symposium on the genetics, evolution, and coordination of insect life cycles organized by Bill Bradshaw and Valerie Brown. The present volume arose from papers contributed by most of the speakers at the symposium, together with papers from other invited authors. In editing the book, I have been assisted greatly by the other authors, particularly Bill Bradshaw, Val Brown and Fritz Taylor. All contributors agreed to referee two other chapters, a system that worked efficiently and effectively: I thank all authors for performing this task in the face of other demands on their time. I would also like to thank Philip Corbet, John Greenslade, Bryan Clarke, and Gillian Thompson of Springer for their help. Nottingham Francis Gilbert January 1990 Contents List of Contributors ....................................................... xiii SECTION I. Genetics of Life-Cycle Traits Introduction William E. Bradshaw ................................................. 3 1 Understanding the Evolution of Insect Life-Cycles: The Role of Genetic Analysis.

The Embryonic Development of Drosophila melanogaster

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Publisher : Springer Science & Business Media
ISBN 13 : 3662024543
Total Pages : 237 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis The Embryonic Development of Drosophila melanogaster by : Jose A. Campos-Ortega

Download or read book The Embryonic Development of Drosophila melanogaster written by Jose A. Campos-Ortega and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: " . . . but our knowledge is so weak that no philosoph er will ever be able to completely explore the nature of even a fly . . . " * Thornas Aquinas "In Syrnbolurn Apostolorum" 079 RSV p/96 This is a monograph on embryogenesis of the fruit fly Drosophi la melanogaster conceived as a reference book on morphology of embryonie development. A monograph of this extent and con tent is not yet available in the literature of Drosophila embryolo gy, and we believe that there is areal need for it. Thanks to the progress achieved during the last ten years in the fields of devel opmental and molecular genetics, work on Drosophila develop ment has considerably expanded creating an even greater need for the information that we present here. Our own interest for wildtype embryonie development arose several years ago, when we began to study the development of mutants. While those studies were going on we repeatedly had occasion to state in sufficiencies in the existing literature about the embryology of the wildtype, so that we undertook investigating many of these problems by ourselves. Convinced that several of our colleagues will have encountered similar difficulties we decided to publish the present monograph. Although not expressely recorded, Thomas Aquinas probably referred to the domestic fly and not to the fruit fly. Irrespective of which fly he meant, however, we know that Thomas was right in any case.

An Introduction to Ecological Genomics

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Publisher : Oxford University Press
ISBN 13 : 0199594686
Total Pages : 374 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis An Introduction to Ecological Genomics by : Nico M. van Straalen

Download or read book An Introduction to Ecological Genomics written by Nico M. van Straalen and published by Oxford University Press. This book was released on 2012 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors also provide a comparative survey of the properties of genomes (genome size, gene families, synteny, and polymorphism) for prokaryotes as well as the main eukaryotic models.

Promoter Associated RNA

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Publisher : Humana
ISBN 13 : 9781493982813
Total Pages : 287 pages
Book Rating : 4.9/5 (828 download)

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Book Synopsis Promoter Associated RNA by : Sara Napoli

Download or read book Promoter Associated RNA written by Sara Napoli and published by Humana. This book was released on 2018-06-09 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is divided in four sections; covering genome wide approaches, techniques for characterize of paRNA structural features are described, selecting pa-RNA, and paRNA therapeutic potential. Chapters describe how siRNAsdirected against paRNAs can be applied in vivo to modulate transcription of important genes controlled by paRNAs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Promoter Associated RNA: Methods and Protocols aims to demonstrate paRNAs as new class of regulatory molecules, to further investigate and value as tools for fine transcriptional tuning.