Genome Chaos

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Genome Chaos

Author : Henry H. Heng
Publisher : Academic Press
ISBN 13 : 0128136367
Total Pages : 556 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Genome Chaos by : Henry H. Heng

Download or read book Genome Chaos written by Henry H. Heng and published by Academic Press. This book was released on 2019-05-25 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine. Bridges basic research and clinical application and provides a foundation for re-examining the results of large-scale omics studies and advancing molecular medicine Gathers the most pressing questions in genomic and cytogenomic research Offers alternative explanations to timely puzzles in the field Contains eight evidence-based chapters that discuss 4d-genomics, genes and genomes as distinct biological entities, genome chaos and macro-cellular evolution, evolutionary cytogenetics and cancer, chromosomal coding and fuzzy inheritance, and more

Genetic Entropy & the Mystery of the Genome

Author : John C. Sanford
Publisher : Ivan Press
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Genetic Entropy & the Mystery of the Genome by : John C. Sanford

Download or read book Genetic Entropy & the Mystery of the Genome written by John C. Sanford and published by Ivan Press. This book was released on 2005 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. John Sanford, a retired Cornell Professor, shows in Genetic Entropy and the Mystery of the Genome that the Primary Axiom is false. The Primary Axiom is the foundational evolutionary premise - that life is merely the result of mutations and natural selection. In addition to showing compelling theoretical evidence that whole genomes can not evolve upward, Dr. Sanford presents strong evidence that higher genomes must in fact degenerate over time. This book strongly refutes the Darwinian concept that man is just the result of a random and pointless natural process.

Debating Cancer

Author : Henry H. Heng
Publisher : World Scientific
ISBN 13 : 9814520853
Total Pages : 463 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Debating Cancer by : Henry H. Heng

Download or read book Debating Cancer written by Henry H. Heng and published by World Scientific. This book was released on 2015-10-08 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cancer research is at a crossroads. Traditionally, cancer has been thought of as a disease of gene mutation, where the stepwise accumulation of cancer gene mutations is the key, and the identification of common gene mutations has been considered to be essential for diagnosis and treatment. Despite extensive research efforts and accumulated knowledge on cancer genes and pathways, the clinical benefits of this traditional approach have been limited. Recently, cancer genome sequencing has revealed an extensive amount of genetic heterogeneity where the long-expected common mutation drivers have been difficult, if not impossible, to identify. These realities ultimately challenge the conceptual framework of current cancer biology. This book introduces a new concept of genome theory of cancer evolution, in an attempt to unify the field. Many important and representative, but often confusing, questions and paradoxes are critically analyzed. By comparing gene- and genome-based theories, the hidden flaws of many popular viewpoints are addressed. This discussion is intended to initiate a much-needed critical re-evaluation of current cancer research."--

Mapping and Sequencing the Human Genome

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Competing on the Edge

Author : Shona L. Brown
Publisher : Harvard Business Press
ISBN 13 : 9780875847542
Total Pages : 322 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Competing on the Edge by : Shona L. Brown

Download or read book Competing on the Edge written by Shona L. Brown and published by Harvard Business Press. This book was released on 1998 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: In their startling new book, authors Brown and Eisenhardt contend that to prosper in today's fiercely competitive business environments, a new paradigm--competing on the edge--must be implemented as a new survival strategy. This book focuses on specific management dilemmas and illustrates solutions that work when the name of the game is change.

Crumbling Genome

Author : Alexey S. Kondrashov
Publisher : John Wiley & Sons
ISBN 13 : 1118952111
Total Pages : 309 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Crumbling Genome by : Alexey S. Kondrashov

Download or read book Crumbling Genome written by Alexey S. Kondrashov and published by John Wiley & Sons. This book was released on 2017-07-12 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre ]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.

I Ching and the Genetic Code

Author : Martin Schönberger
Publisher :
ISBN 13 : 9780943358376
Total Pages : 0 pages
Book Rating : 4.3/5 (583 download)

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Book Synopsis I Ching and the Genetic Code by : Martin Schönberger

Download or read book I Ching and the Genetic Code written by Martin Schönberger and published by . This book was released on 1992 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The universal claims of both the I Ching, "the book of changes", the compendium of Chinese natural knowledge and the genetic code, "the book of life", encouraged Dr. Schönberger to establish the hypothesis of a general system in nature. He has verified in numerous parallels the congruence of both the I Ching code and the genetic code. The sensational results are detailed for the first time in this book. The "I Ching & the Genetic Code" is an important and exciting link between science and spirituality!

Chaos Engineering

Author : Casey Rosenthal
Publisher : "O'Reilly Media, Inc."
ISBN 13 : 1492043818
Total Pages : 312 pages
Book Rating : 4.4/5 (92 download)

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Book Synopsis Chaos Engineering by : Casey Rosenthal

Download or read book Chaos Engineering written by Casey Rosenthal and published by "O'Reilly Media, Inc.". This book was released on 2020-04-06 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: As more companies move toward microservices and other distributed technologies, the complexity of these systems increases. You can't remove the complexity, but through Chaos Engineering you can discover vulnerabilities and prevent outages before they impact your customers. This practical guide shows engineers how to navigate complex systems while optimizing to meet business goals. Two of the field's prominent figures, Casey Rosenthal and Nora Jones, pioneered the discipline while working together at Netflix. In this book, they expound on the what, how, and why of Chaos Engineering while facilitating a conversation from practitioners across industries. Many chapters are written by contributing authors to widen the perspective across verticals within (and beyond) the software industry. Learn how Chaos Engineering enables your organization to navigate complexity Explore a methodology to avoid failures within your application, network, and infrastructure Move from theory to practice through real-world stories from industry experts at Google, Microsoft, Slack, and LinkedIn, among others Establish a framework for thinking about complexity within software systems Design a Chaos Engineering program around game days and move toward highly targeted, automated experiments Learn how to design continuous collaborative chaos experiments

Life's Ratchet

Author : Peter M. Hoffmann
Publisher :
ISBN 13 : 0465022537
Total Pages : 290 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Life's Ratchet by : Peter M. Hoffmann

Download or read book Life's Ratchet written by Peter M. Hoffmann and published by . This book was released on 2012-10-30 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life, Hoffman argues, emerges from the random motions of atoms filtered through the sophisticated structures of our evolved machinery. People are essentially giant assemblies of interacting nanoscale machines.

Sweet Chaos

Author : Carol Brightman
Publisher : Simon and Schuster
ISBN 13 : 0671011170
Total Pages : 372 pages
Book Rating : 4.6/5 (71 download)

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Book Synopsis Sweet Chaos by : Carol Brightman

Download or read book Sweet Chaos written by Carol Brightman and published by Simon and Schuster. This book was released on 1999-09 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: A social and cultural history of the Grateful Dead, America's greatest folk/rock institution, by a "National Book Critics Circle Award"-winning author. 8-page photo insert.

The Chaos Machine

Author : Max Fisher
Publisher : Hachette UK
ISBN 13 : 0316703311
Total Pages : 419 pages
Book Rating : 4.3/5 (167 download)

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Book Synopsis The Chaos Machine by : Max Fisher

Download or read book The Chaos Machine written by Max Fisher and published by Hachette UK. This book was released on 2022-09-06 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finalist for the Helen Bernstein Book Award for Excellence in Journalism From a New York Times investigative reporter, this “authoritative and devastating account of the impacts of social media” (New York Times Book Review) tracks the high-stakes inside story of how Big Tech’s breakneck race to drive engagement—and profits—at all costs fractured the world. The Chaos Machine is “an essential book for our times” (Ezra Klein). We all have a vague sense that social media is bad for our minds, for our children, and for our democracies. But the truth is that its reach and impact run far deeper than we have understood. Building on years of international reporting, Max Fisher tells the gripping and galling inside story of how Facebook, Twitter, YouTube, and other social network preyed on psychological frailties to create the algorithms that drive everyday users to extreme opinions and, increasingly, extreme actions. As Fisher demonstrates, the companies’ founding tenets, combined with a blinkered focus on maximizing engagement, have led to a destabilized world for everyone. Traversing the planet, Fisher tracks the ubiquity of hate speech and its spillover into violence, ills that first festered in far-off locales, to their dark culmination in America during the pandemic, the 2020 election, and the Capitol Insurrection. Through it all, the social-media giants refused to intervene in any meaningful way, claiming to champion free speech when in fact what they most prized were limitless profits. The result, as Fisher shows, is a cultural shift toward a world in which people are polarized not by beliefs based on facts, but by misinformation, outrage, and fear. His narrative is about more than the villains, however. Fisher also weaves together the stories of the heroic outsiders and Silicon Valley defectors who raised the alarm and revealed what was happening behind the closed doors of Big Tech. Both panoramic and intimate, The Chaos Machine is the definitive account of the meteoric rise and troubled legacy of the tech titans, as well as a rousing and hopeful call to arrest the havoc wreaked on our minds and our world before it’s too late.

The Selfish Gene

Author : Richard Dawkins
Publisher : Oxford University Press, USA
ISBN 13 : 9780192860927
Total Pages : 372 pages
Book Rating : 4.8/5 (69 download)

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Book Synopsis The Selfish Gene by : Richard Dawkins

Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press, USA. This book was released on 1989 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science

The Nonlinear Workbook

Author : Willi-Hans Steeb
Publisher : World Scientific Publishing Company
ISBN 13 : 9814583499
Total Pages : 684 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis The Nonlinear Workbook by : Willi-Hans Steeb

Download or read book The Nonlinear Workbook written by Willi-Hans Steeb and published by World Scientific Publishing Company. This book was released on 2014-11-14 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nonlinear Workbook provides a comprehensive treatment of all the techniques in nonlinear dynamics together with C++, Java and SymbolicC++ implementations. The book not only covers the theoretical aspects of the topics but also provides the practical tools. To understand the material, more than 100 worked out examples and 160 ready to run programs are included. Each chapter provides a collection of interesting problems. New topics added to the 6th edition are Swarm Intelligence, Quantum Cellular Automata, Hidden Markov Model and DNA, Birkhoff's ergodic theorem and chaotic maps, Banach fixed point theorem and applications, tau-wavelets of Haar, Boolean derivatives and applications, and Cartan forms and Lagrangian. Request Inspection Copy

The Nonlinear Workbook

Author : Willi-Hans Steeb
Publisher : World Scientific Publishing Company
ISBN 13 : 9813100702
Total Pages : 644 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis The Nonlinear Workbook by : Willi-Hans Steeb

Download or read book The Nonlinear Workbook written by Willi-Hans Steeb and published by World Scientific Publishing Company. This book was released on 2011-03-16 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nonlinear Workbook provides a comprehensive treatment of all the techniques in nonlinear dynamics together with C++, Java and SymbolicC++ implementations. The book not only covers the theoretical aspects of the topics but also provides the practical tools. To understand the material, more than 100 worked out examples and 150 ready to run programs are included. New topics added to the fifth edition are Langton's ant, chaotic data communication, self-controlling feedback, differential forms and optimization, T-norms and T-conorms with applications.

The Nonlinear Workbook

Author : Willi-Hans Steeb
Publisher : World Scientific Publishing Company
ISBN 13 : 9813106093
Total Pages : 640 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis The Nonlinear Workbook by : Willi-Hans Steeb

Download or read book The Nonlinear Workbook written by Willi-Hans Steeb and published by World Scientific Publishing Company. This book was released on 2002-12-30 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of nonlinear dynamical systems has advanced tremendously in the last 15 years, making a big impact on science and technology. This book provides all the techniques and methods used in nonlinear dynamics. The concepts and underlying mathematics are discussed in detail. The numerical and symbolic methods are implemented in C++, SymbolicC++ and Java. Object-oriented techniques are also applied. The book contains more than 100 ready-to-run programs. The text has also been designed for a one-year course at both the junior and senior levels in nonlinear dynamics. The topics discussed in the book are part of e-learning and distance learning courses conducted by the International School for Scientific Computing. Request Inspection Copy

The Nonlinear Workbook

Author : Willi-Hans Steeb
Publisher : World Scientific Publishing Company
ISBN 13 : 9813107243
Total Pages : 628 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis The Nonlinear Workbook by : Willi-Hans Steeb

Download or read book The Nonlinear Workbook written by Willi-Hans Steeb and published by World Scientific Publishing Company. This book was released on 2008-06-17 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of nonlinear dynamical systems has advanced tremendously in the last 20 years, making a big impact on science and technology. This book provides all the techniques and methods used in nonlinear dynamics. The concepts and underlying mathematics are discussed in detail. The numerical and symbolic methods are implemented in C++, SymbolicC++ and Java. Object-oriented techniques are also applied. The book contains more than 150 ready-to-run programs. The text has also been designed for a one-year course at both the junior and senior levels in nonlinear dynamics. The topics discussed in the book are part of e-learning and distance learning courses conducted by the International School for Scientific Computing, University of Johannesburg.

Deep Simplicity

Author : John Gribbin
Publisher : Penguin UK
ISBN 13 : 0141042214
Total Pages : 480 pages
Book Rating : 4.1/5 (41 download)

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Book Synopsis Deep Simplicity by : John Gribbin

Download or read book Deep Simplicity written by John Gribbin and published by Penguin UK. This book was released on 2009-08-27 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Gribbin takes us through the basics with his customary talent for accessibility and clarity' Sunday Times The world around us can be a complex, confusing place. Earthquakes happen without warning, stock markets fluctuate, weather forecasters seldom seem to get it right - even other people continue to baffle us. How do we make sense of it all? In fact, John Gribbin reveals, our seemingly random universe is actually built on simple laws of cause and effect that can explain why, for example, just one vehicle braking can cause a traffic jam; why wild storms result from a slight atmospheric change; even how we evolved from the most basic materials. Like a zen painting, a fractal image or the pattern on a butterfly's wings, simple elements form the bedrock of a sophisticated whole. Synthesizing chaos and complexity theory for the perplexed, Deep Simplicity brilliantly illuminates the harmony underlying our existence.