Genetic Control of Natural Resistance to Infection and Malignancy

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Publisher : Elsevier
ISBN 13 : 032314439X
Total Pages : 621 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Genetic Control of Natural Resistance to Infection and Malignancy by : Emil Skamene

Download or read book Genetic Control of Natural Resistance to Infection and Malignancy written by Emil Skamene and published by Elsevier. This book was released on 2012-12-02 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Control of Natural Resistance to Infection and Malignancy is a collection of papers presented at the 1980 Proceedings of an International Symposium of the Canadian Society for Immunology held in Montreal, Quebec. It provides information about the different models of genetic resistance to various diseases. The book offers an overview of the genetic determination of the susceptibility or resistance to infection and malignancy. It also discusses the importance of genetic resistance not only in the first-line observation of infections and tumors, but also in chemotherapy and immunotherapy. It then explains the genetic control of resistance to parasitic, bacterial, and virus infections, as well as to tumor growth. It further discusses the genetic control of macrophage differentiation and function.

GENETIC CONTROL OF NATURAL RESISTANCE TO INFECTION AND MALIGNANCY : PROCEEDINGS OF AN INTERNATIONAL SYMPOSIUM OF THE CANADIAN SOCIETY FOR IMMUNOLOGY HELD IN MONTREAL, QUEBEC, MARCH 18-20, 1980

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ISBN 13 : 9780126476804
Total Pages : 0 pages
Book Rating : 4.4/5 (768 download)

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Book Synopsis GENETIC CONTROL OF NATURAL RESISTANCE TO INFECTION AND MALIGNANCY : PROCEEDINGS OF AN INTERNATIONAL SYMPOSIUM OF THE CANADIAN SOCIETY FOR IMMUNOLOGY HELD IN MONTREAL, QUEBEC, MARCH 18-20, 1980 by :

Download or read book GENETIC CONTROL OF NATURAL RESISTANCE TO INFECTION AND MALIGNANCY : PROCEEDINGS OF AN INTERNATIONAL SYMPOSIUM OF THE CANADIAN SOCIETY FOR IMMUNOLOGY HELD IN MONTREAL, QUEBEC, MARCH 18-20, 1980 written by and published by . This book was released on 1980 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Control of Host Resistance to Infection and Malignancy

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Author :
Publisher : New York : Liss
ISBN 13 :
Total Pages : 898 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetic Control of Host Resistance to Infection and Malignancy by : Emil Skamene

Download or read book Genetic Control of Host Resistance to Infection and Malignancy written by Emil Skamene and published by New York : Liss. This book was released on 1985 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Natural Resistance to Tumors and Viruses

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Publisher : Springer Science & Business Media
ISBN 13 : 3642680690
Total Pages : 135 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Natural Resistance to Tumors and Viruses by : O. Haller

Download or read book Natural Resistance to Tumors and Viruses written by O. Haller and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural resistance is now coming to be recognized as a potentially important phenomenon in host defense against infection and ma lignancy. Genetically controlled resistance mechanisms are usUally effective early in infection and before conventional immune responses are generated. Comparisons of experimental systems where natural resistance plays a prominent role demon strate the complexities of the host defense mechanisms involved, as evidenced in the present volume. Nevertheless, some com mon components of genetic resistance are discernible and largely comprise natural killer cells, macrophages, and interferon These and additional factors would seem to constitute a first line of de fense in host resistance against both viruses and tumors. It is evi dent that considerable variation in the relative importance of di stinct mechanisms may be found among various resistance sy stems and that, most likely, additional effector functions will be discovered. Resistance to tumors and most viruses is under polygenic control, has a complex mode of inheritance, and depends on appro priately complex effector mechanisms. Instances, however, whe re a single gene locus determines resistance or susceptibility to a virus, as in the case of resistance to flaviviruses or influenza viru ses, would seem to offer good prospects for elucidating the basic factors involved. Resistance to influenza virus would indeed seem to represent a comparatively simple situation: resistance is expressed at the host cell level, and interferon is its main media tor. The present volume provides insight into current concepts of such resistance mechanisms.

Genetic Control of the Susceptibility to Bacterial Infection

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Publisher : Springer Science & Business Media
ISBN 13 : 3642709869
Total Pages : 181 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Genetic Control of the Susceptibility to Bacterial Infection by : David E. Briles

Download or read book Genetic Control of the Susceptibility to Bacterial Infection written by David E. Briles and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunological Disorders in Mice

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Publisher : CRC Press
ISBN 13 : 9780849356353
Total Pages : 288 pages
Book Rating : 4.3/5 (563 download)

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Book Synopsis Immunological Disorders in Mice by : Blanka Rihova

Download or read book Immunological Disorders in Mice written by Blanka Rihova and published by CRC Press. This book was released on 1990-11-21 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunological Disorders in Mice focuses on immunological reactions and diseases based on models provided through studies on genetically based immunological disorders in inbred strains of mice. The book discusses various defects affecting all levels of immunological response, featuring new data on "classical" mutations, as well as information regarding lesser known immune defects. New areas presented include genetic manipulation, ontogenetic aspects, clinical implications, the effect of drugs on immunodefective strains, and neuroendocrine regulation. A critical evaluation of the data presented through these studies on immune disorders in mice will facilitate the understanding of immunological processes and have significant application in clinical practice. Theoretical immunologists, animal breeding companies, and clinical immunologists will find this text invaluable.

Avian Cellular Immunology

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Publisher : Routledge
ISBN 13 : 1351464957
Total Pages : 224 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Avian Cellular Immunology by : JagdevM. Sharma

Download or read book Avian Cellular Immunology written by JagdevM. Sharma and published by Routledge. This book was released on 2018-01-29 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge regarding avian cellular immunity has expanded rapidly within the last few years and new information continues to accumulate. It is now a well-established fact that cell-mediated immunity plays a major role in the defense against neoplastic and non-neoplastic diseases in chickens. The principle objective of Avian Cellular Immunology is to compile the latest information available on various aspects of avian cellular immunity. The book contains chapters written by leading experts in the field and covers topics including cell surface markers, T-cell immunity, natural immune functions, the role of macrophages in cellular immune functions, cellular immune suppression and tolerance, cellular immune systems in avian species other than chickens, the role of cellular immunity in neoplastic and non-neoplastic viral diseases, cell-mediated immune mechanisms in bacterial and parasitic infections, and autoimmune disorders.

Immunobiology of Parasites and Parasitic Infections

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Publisher : Springer Science & Business Media
ISBN 13 : 1468445715
Total Pages : 512 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Immunobiology of Parasites and Parasitic Infections by : John Marchalonis

Download or read book Immunobiology of Parasites and Parasitic Infections written by John Marchalonis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The phenomena involved in infections of man and domestic animals with metazoan or protozoan parasites present formidable practical problems as well as a theoretical challenge to immunologists, molecular biologists, and evolu tionary biologists. With respect to the public health and economic problems, malaria, for example, remains a major health problem with approximately 200 million people being infected yearly and, on the basis of World Health Organiza tion estimates, more than 1 million children die each year of malaria infections (Chapter 4). This volume addresses state-of-the-art immunologic approaches to the development of vaccines for parasitic diseases (Chapter 9) and analyses of studies bearing on the antigenic characterization of protozoan and metazoan parasites (Chapters 4, 5, and 7), on investigations of the role of precise mecha nisms underlying natural resistance or non permissiveness of the host to parasitic infections (Chapters 1, 2, and 12), on induced mechanisms including the genera tion of parasite-specific T-cell lines and clones (Chapter 6), and on the generation of monoclonal antibodies (Chapters 4 and 5) to parasite antigens of distinct de velopmental stages. Great progress has been made in characterizing parasite antigens capable of inducing a protective response in the vaccinated host; further progress in this area strongly depends on biochemistry and molecular biology with the long-term goal of synthesizing such antigens chemically or producing them by means of recombinant DNA technology (Chapter 4).

Macrophages & Cancer

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Publisher : CRC Press
ISBN 13 : 1000012972
Total Pages : 224 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Macrophages & Cancer by : Gloria H. Heppner

Download or read book Macrophages & Cancer written by Gloria H. Heppner and published by CRC Press. This book was released on 2019-06-04 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1988, this book offers a full, comprehensive guide into the relationship between macrophages and Cancer. Carefully compiled and filled with a vast repertoire of notes and references this book serves as a useful reference for Students of Medicine, Oncology and other practitioners in their respective fields.

Biology of Salmonella

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Publisher : Springer Science & Business Media
ISBN 13 : 1461528542
Total Pages : 456 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Biology of Salmonella by : Filipe Cabello

Download or read book Biology of Salmonella written by Filipe Cabello and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Salmonella infections of man and animals continue to be a distressing health problem worldwide. Far from disappearing, the incidence of typhoid fever in developing countries may be far higher than we had imagined. Salmonella food poisoning has increased to one of the major causes of gastroenteritis in the developed world, in itself also an indication that animal salmonellosis is still a major cause for concern. The situation requires a concerted multidisciplinary research effort in order to generate the new information and technology needed to assist in the control of these diseases. This concept was the driving force behind the NATO Advanced Research Workshop on "Biology of Salmonella" held at Portorosa, Messina, Italy, May 11-15, 1992. With additional support from the University of Messina, Medeva Group Research (UK) and the Swiss Serum and Vaccine Research Institute, the meeting brought together epidemiologists, microbiologists, molecular biologists, immunologists and clinicians. All the participants were actively working on different but related aspects of Salmonella and salmonellosis, with most of the leading laboratories worldwide being represented. The workshop provided an excellent opportunity for interdisciplinary consultation; it is not often that the topic of Salmonella and salmonellosis is covered to such breadth and depth in one extended meeting. Keynote addresses by invited speakers were interspersed with offered papers, many by younger members of the scientific community, and this volume presents the collated manuscripts of the lectures and extended summaries of the offered papers.

Published Scientific Papers of the National Institutes of Health

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Publisher :
ISBN 13 :
Total Pages : 480 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Published Scientific Papers of the National Institutes of Health by : National Institutes of Health (U.S.)

Download or read book Published Scientific Papers of the National Institutes of Health written by National Institutes of Health (U.S.) and published by . This book was released on 1982 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each issue lists papers published during the preceding year.

Scientific Directory and Annual Bibliography

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Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Scientific Directory and Annual Bibliography by : National Institutes of Health (U.S.)

Download or read book Scientific Directory and Annual Bibliography written by National Institutes of Health (U.S.) and published by . This book was released on 1982 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Physiology of Immunity

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Publisher : CRC Press
ISBN 13 : 9780849380334
Total Pages : 464 pages
Book Rating : 4.3/5 (83 download)

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Book Synopsis The Physiology of Immunity by : James A. Marsh

Download or read book The Physiology of Immunity written by James A. Marsh and published by CRC Press. This book was released on 1996-07-24 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of neuroendocrine-immune interactions has become a highly visible and fast-growing segment of mainstream immunology. This book provides an overview of the immune system and in-depth coverage of the many different areas that make up neuroendocrine-immune research. The main emphasis is on the physiology of the processes involved, stressing an integrated approach to immunology. The text is organized in seven sections, beginning with an introduction to the immune system. Section II outlines how the central nervous system (CNS) communicates with central and peripheral lymphoid organs. Section III provides information on factors from the immune system that act as messengers to the CNS. The metabolic regulation of growth and development is discussed in Section IV. Section V examines the interactions occurring between the reproductive and immune systems. The effects of other physiologic stressors on immunity are reviewed in Section VI. Section VII considers cyclic and periodic influences on the immune system. Finally, there is a consideration of a new unifying theory for immunology. Students, researchers, clinicians, and veterinary scientists can discover new areas of interest in specific diseases and immune interactions in this novel presentation.

Genetic Toxicology

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Publisher : Springer Science & Business Media
ISBN 13 : 1468443526
Total Pages : 549 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Genetic Toxicology by : Raymond F. Fleck

Download or read book Genetic Toxicology written by Raymond F. Fleck and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: To meet the needs of an ever-growing world population for food and fiber, agriculture uses an arsenal of chemicals to control insects, weeds and other pests that compete with man in the agricultural arena. In addition to their intended effect, many of these biologically active materials affect non-target organisms including man himself. There is concern about the resulting occupational exposure of those who work in agriculture and the environmental health of those who live in rural areas. Unintended side effects from the use of agricultural chemicals are further complicated by the dispersal of these substances well beyond the area of immediate use, through food chains, atmospheric transport, irrigation runoff, percolation to and diffusion through ground water, sometimes giving rise to public health and environmental problems at a distance from the place of application. In addition to toxic substances introduced into the agro ecosystem by man, one must be concerned about naturally occurring agents including mfcotoxins, plant poisons, infective biological agents and the levels of certain heavy metals. The formation of toxic substances, many of them mutagenic, during cooking and other processing of food is a related problem. While acute effects are more immediate and somewhat readily discerned, chronic and genetic effects tend to be more obscure and sometimes surface in a crisis situation long after substantial damage has been sustained. Genotoxicity assays and epidemiological studies play increasing roles in predicting and evaluating long term effects of low-level exposure to toxic materials.

Host Defenses to Intracellular Pathogens

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Publisher : Springer Science & Business Media
ISBN 13 : 1468444816
Total Pages : 525 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Host Defenses to Intracellular Pathogens by : Toby K. Eisenstein

Download or read book Host Defenses to Intracellular Pathogens written by Toby K. Eisenstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject matter of this volume was the basis for a confer ence held in Philadelphia in June, 1981, and is an important one in the contemporary area of how the host interacts with micro organisms. In conception, it grew out of a graduate course entitled, "The Infectious Process," which has been taught in the Department of Microbiology and Immunology at Temple University School of Medicine during the past twelve years. This course has explored the broad areas of mechanisms of microbial pathogenesis and host resistance by in-depth consideration of selected models of experimental infection and immunity, as well as the clinical literature. It is noteworthy that there is no adequate text for this material, as the subject matter naturally crosses a wide spectrum of traditional disciplinary lines, encompassing topics as diverse as the mechanisms of action of bacterial toxins, the role of complement and antibody in phagocytosis, and the importance of cross-reacting bacterial polysaccharide antigens in vaccine development. A major portion of the course has always considered "cellular immunity" as it applies to host defenses to intracellular pathogens. It is in this area that the necessity for amalgamation of information from different disciplines is most evident, for one must be intimately concerned with the interactions between the microbe and the phagocyte, both before and after specific immune recognition.

Tuberculosis and the Tubercle Bacillus

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Publisher : John Wiley & Sons
ISBN 13 : 1555819567
Total Pages : 741 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Tuberculosis and the Tubercle Bacillus by : William R. Jacobs, Jr.

Download or read book Tuberculosis and the Tubercle Bacillus written by William R. Jacobs, Jr. and published by John Wiley & Sons. This book was released on 2020-07-15 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: Can today's innovative practices and molecular tools tame this ancient disease? One third of the world's population is infected with tuberculosis (TB), with about 10 million new cases annually. To combat TB and its agent, Mycobacterium tuberculosis, the World Health Organization launched The End TB Strategy, which aims to slash the suffering and cost of TB by 2035. This makes the second edition of Tuberculosis and the Tubercle Bacillus, edited by Jacobs, McShane, Mizrahi, and Orme, an extremely valuable resource for scientists and clinicians. The editors have gathered their colleagues from around the world to present the latest on the molecular biology of M. tuberculosis and related species, the host-pathogen interactions that enable invasion, and the host's immune response to M. tuberculosis infection. The basic, clinical, and translational research presented in this book supports the goals of WHO's End TB Strategy by driving toward the development of effective vaccines, rapid molecular diagnostics, and anti-TB drugs. Creating an effective tuberculosis vaccine. Understand the innate and adaptive immune response to M. tuberculosis infection, its study in established animal models, and how this information is being used to develop new vaccines against TB. Formulating new antituberculosis drugs. Learn the challenges and methods for evaluating new drugs in preclinical trials with a focus on drugs that work against "persisters" and those that act on the electron transport complex and ATP synthase of M. tuberculosis. Overcoming the challenges of diagnosing tuberculosis. Review new diagnostic tools that are simple, rapid, affordable, specific, sensitive, and safe, including molecular-based diagnostic methods such as GeneXpert MTB/RIF. Using molecular, genomic, and bioinformatics tools to understand the biology and evolution of Mycobacterium. Explore current research on the molecular mechanisms that M. tuberculosis uses to evade the immune system, enter a state of nonreplicating persistence, and become reactivated. The second edition of Tuberculosis and the Tubercle Bacillus presents the latest research on a microorganism that is exquisitely well adapted to its human host. This pathogen continues to confound scientists, clinicians, and public health specialists, who will all find much valuable information in this comprehensive set of reviews.

Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1550 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1550 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.