Genetic Approaches In The Prevention Of Mental Disorders

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Genetic Approaches in the Prevention of Mental Disorders

Author : Victor Bulyzhenkov
Publisher : Springer Science & Business Media
ISBN 13 : 3662074214
Total Pages : 186 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Genetic Approaches in the Prevention of Mental Disorders by : Victor Bulyzhenkov

Download or read book Genetic Approaches in the Prevention of Mental Disorders written by Victor Bulyzhenkov and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: At least 40 million people in the worId suffer from the most severe forms of mental disorder such as schizophrenia and some 300 million more are affected by less severe but still incapacitating forms of these conditions, including, for example, drug and alcohol dependence and the consequences of brain trauma. The enor mous magnitude of human suffering and the economic losses usually linked of these disorders make them a problem of major public health importance. Recent years have brought with them scientific discoveries which have made it possible to successfully treat most mental disorders and to prevent many others. Some of them, however, cannot be prevented on the basis of today's knowledge, and their treatment remains palliative: further progress in their management awaits an improvement in our understanding of mechanisms by which they come into existence and of factors which influence their course. Recent years have also seen a significant increase in knowledge about genetic factors influencing the occurrence and course of a variety of diseases, for example, cystic fibrosis, Duchenne type muscular dystrophy, thalassemia, and hyperten sion. Some of this knowledge and some of the methods that have been developed to obtain it could have direct relevance to the search for a c1earer comprehension of the pathogenesis of mental disorder.

Genetic Approaches to Mental Disorders

Author : Elliot S. Gershon
Publisher : American Psychiatric Pub
ISBN 13 :
Total Pages : 412 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetic Approaches to Mental Disorders by : Elliot S. Gershon

Download or read book Genetic Approaches to Mental Disorders written by Elliot S. Gershon and published by American Psychiatric Pub. This book was released on 1994 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 1940s, the American Psychopathological Association has been a driving force in psychiatric genetic research. Having studied the Kallmann and Kety Hoch Award papers, many researchers have attempted to advance psychiatric genetic knowledge from epidemiological findings to biological findings. Genetic Approaches to Mental Disorders provides the latest information on the relationship between genetics and mental disorders. Divided into four sections, this book presents analysis of the genetic data, linkage mapping and association, debate over genetic Kraepelinian dichotomy, and mapping and association results in psychiatry.

Reducing Risks for Mental Disorders

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309049393
Total Pages : 636 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Reducing Risks for Mental Disorders by : Institute of Medicine

Download or read book Reducing Risks for Mental Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 1994-01-01 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of how to reduce risk factors for mental disorders has expanded remarkably as a result of recent scientific advances. This study, mandated by Congress, reviews those advances in the context of current research and provides a targeted definition of prevention and a conceptual framework that emphasizes risk reduction. Highlighting opportunities for and barriers to interventions, the book draws on successful models for the prevention of cardiovascular disease, injuries, and smoking. In addition, it reviews the risk factors associated with Alzheimer's disease, schizophrenia, alcohol abuse and dependence, depressive disorders, and conduct disorders and evaluates current illustrative prevention programs. The models and examination provide a framework for the design, application, and evaluation of interventions intended to prevent mental disorders and the transfer of knowledge about prevention from research to clinical practice. The book presents a focused research agenda, with recommendations on how to develop effective intervention programs, create a cadre of prevention researchers, and improve coordination among federal agencies.

Personalized Psychiatry

Author : Bernhard Baune
Publisher : Academic Press
ISBN 13 : 0128131772
Total Pages : 604 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Personalized Psychiatry by : Bernhard Baune

Download or read book Personalized Psychiatry written by Bernhard Baune and published by Academic Press. This book was released on 2019-10-16 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

The New Genetics of Mental Illness

Author : Peter McGuffin
Publisher : Butterworth-Heinemann
ISBN 13 : 1483164276
Total Pages : 316 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis The New Genetics of Mental Illness by : Peter McGuffin

Download or read book The New Genetics of Mental Illness written by Peter McGuffin and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New Genetics of Mental Illness is a collection of papers that discusses the advancement of molecular biology in the context of psychiatry. The book presents papers that are organized thematically. The text first discusses the basics of biology and quantitative models, and then proceeds to covering linkage analysis. Next, the book deals with various mental disorders, including schizophrenia, eating disorders, and developmental disorders. The remaining materials turn their attention to dementia and Huntington’s disease. The book will be of great use to researchers and practitioners of behavioral sciences, such as psychology and psychiatry.

International Perspectives in Values-Based Mental Health Practice

Author : Drozdstoy Stoyanov
Publisher : Springer Nature
ISBN 13 : 3030478521
Total Pages : 415 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis International Perspectives in Values-Based Mental Health Practice by : Drozdstoy Stoyanov

Download or read book International Perspectives in Values-Based Mental Health Practice written by Drozdstoy Stoyanov and published by Springer Nature. This book was released on 2020-12-11 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers essential information on values-based practice (VBP): the clinical skills involved, teamwork and person-centered care, links between values and evidence, and the importance of partnerships in shared decision-making. Different cultures have different values; for example, partnership in decision-making looks very different, from the highly individualized perspective of European and North American cultures to the collective and family-oriented perspectives common in South East Asia. In turn, African cultures offer yet another perspective, one that falls between these two extremes (called batho pele). The book will benefit everyone concerned with the practical challenges of delivering mental health services. Accordingly, all contributions are developed on the basis of case vignettes, and cover a range of situations in which values underlie tensions or uncertainties regarding how to proceed in clinical practice. Examples include the patient’s autonomy and best interest, the physician’s commitment to establishing high standards of clinical governance, clinical versus community best interest, institutional versus clinical interests, patients insisting on medically unsound but legal treatments etc. Thus far, VBP publications have mainly dealt with clinical scenarios involving individual values (of clinicians and patients). Our objective with this book is to develop a model of VBP that is culturally much broader in scope. As such, it offers a vital resource for mental health stakeholders in an increasingly inter-connected world. It also offers opportunities for cross-learning in values-based practice between cultures with very different clinical care traditions.

Disruptive Behavior Disorders

Author : Patrick H. Tolan
Publisher : Springer Science & Business Media
ISBN 13 : 1461475570
Total Pages : 211 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Disruptive Behavior Disorders by : Patrick H. Tolan

Download or read book Disruptive Behavior Disorders written by Patrick H. Tolan and published by Springer Science & Business Media. This book was released on 2013-07-09 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aggressive behavior among children and adolescents has confounded parents and perplexed professionals—especially those tasked with its treatment and prevention—for countless years. As baffling as these behaviors are, however, recent advances in neuroscience focusing on brain development have helped to make increasing sense of their complexity. Focusing on their most prevalent forms, Oppositional Defiant Disorder and Conduct Disorder, Disruptive Behavior Disorders advances the understanding of DBD on a number of significant fronts. Its neurodevelopmental emphasis within an ecological approach offers links between brain structure and function and critical environmental influences and the development of these specific disorders. The book's findings and theories help to differentiate DBD within the contexts of normal development, non-pathological misbehavior and non-DBD forms of pathology. Throughout these chapters are myriad implications for accurate identification, effective intervention and future cross-disciplinary study. Key issues covered include: Gene-environment interaction models. Neurobiological processes and brain functions. Callous-unemotional traits and developmental pathways. Relationships between gender and DBD. Multiple pathways of familial transmission. Disruptive Behavior Disorders is a groundbreaking resource for researchers, scientist-practitioners and graduate students in clinical child and school psychology, psychiatry, educational psychology, prevention science, child mental health care, developmental psychology and social work.

Principles of Psychiatric Genetics

Author : John I. Nurnberger
Publisher : Cambridge University Press
ISBN 13 : 0521896495
Total Pages : 415 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Principles of Psychiatric Genetics by : John I. Nurnberger

Download or read book Principles of Psychiatric Genetics written by John I. Nurnberger and published by Cambridge University Press. This book was released on 2012-09-13 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.

The Social Determinants of Mental Health

Author : Michael T. Compton
Publisher : American Psychiatric Pub
ISBN 13 : 1585625175
Total Pages : 260 pages
Book Rating : 4.5/5 (856 download)

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Book Synopsis The Social Determinants of Mental Health by : Michael T. Compton

Download or read book The Social Determinants of Mental Health written by Michael T. Compton and published by American Psychiatric Pub. This book was released on 2015-04-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Determinants of Mental Health aims to fill the gap that exists in the psychiatric, scholarly, and policy-related literature on the social determinants of mental health: those factors stemming from where we learn, play, live, work, and age that impact our overall mental health and well-being. The editors and an impressive roster of chapter authors from diverse scholarly backgrounds provide detailed information on topics such as discrimination and social exclusion; adverse early life experiences; poor education; unemployment, underemployment, and job insecurity; income inequality, poverty, and neighborhood deprivation; food insecurity; poor housing quality and housing instability; adverse features of the built environment; and poor access to mental health care. This thought-provoking book offers many beneficial features for clinicians and public health professionals: Clinical vignettes are included, designed to make the content accessible to readers who are primarily clinicians and also to demonstrate the practical, individual-level applicability of the subject matter for those who typically work at the public health, population, and/or policy level. Policy implications are discussed throughout, designed to make the content accessible to readers who work primarily at the public health or population level and also to demonstrate the policy relevance of the subject matter for those who typically work at the clinical level. All chapters include five to six key points that focus on the most important content, helping to both prepare the reader with a brief overview of the chapter's main points and reinforce the "take-away" messages afterward. In addition to the main body of the book, which focuses on selected individual social determinants of mental health, the volume includes an in-depth overview that summarizes the editors' and their colleagues' conceptualization, as well as a final chapter coauthored by Dr. David Satcher, 16th Surgeon General of the United States, that serves as a "Call to Action," offering specific actions that can be taken by both clinicians and policymakers to address the social determinants of mental health. The editors have succeeded in the difficult task of balancing the individual/clinical/patient perspective and the population/public health/community point of view, while underscoring the need for both groups to work in a unified way to address the inequities in twenty-first century America. The Social Determinants of Mental Health gives readers the tools to understand and act to improve mental health and reduce risk for mental illnesses for individuals and communities. Students preparing for the Medical College Admission Test (MCAT) will also benefit from this book, as the MCAT in 2015 will test applicants' knowledge of social determinants of health. The social determinants of mental health are not distinct from the social determinants of physical health, although they deserve special emphasis given the prevalence and burden of poor mental health.

Genetic Approaches to Mental Disorders

Author : Elliot S. Gershon
Publisher : American Psychiatric Pub
ISBN 13 : 9780880489515
Total Pages : 404 pages
Book Rating : 4.4/5 (895 download)

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Book Synopsis Genetic Approaches to Mental Disorders by : Elliot S. Gershon

Download or read book Genetic Approaches to Mental Disorders written by Elliot S. Gershon and published by American Psychiatric Pub. This book was released on 1994 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 1940s, the American Psychopathological Association has been a driving force in psychiatric genetic research. Having studied the Kallmann and Kety Hoch Award papers, many researchers have attempted to advance psychiatric genetic knowledge from epidemiological findings to biological findings. Genetic Approaches to Mental Disorders provides the latest information on the relationship between genetics and mental disorders. Divided into four sections, this book presents analysis of the genetic data, linkage mapping and association, debate over genetic Kraepelinian dichotomy, and mapping and association results in psychiatry.

Genes, Memes, Culture, and Mental Illness

Author : Hoyle Leigh
Publisher : Springer Science & Business Media
ISBN 13 : 1441956719
Total Pages : 292 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Genes, Memes, Culture, and Mental Illness by : Hoyle Leigh

Download or read book Genes, Memes, Culture, and Mental Illness written by Hoyle Leigh and published by Springer Science & Business Media. This book was released on 2010-06-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: What produces mental illness: genes, environment, both,neither? The answer can be found in memes—replicable units of information linking genes and environment in the memory and in culture—whose effects on individual brain development can be benign or toxic. This book reconceptualizes mental disorders as products of stressful gene-meme interactions and introduces a biopsychosocial template for meme-based diagnosis and treatment. A range of therapeutic modalities, both broad-spectrum (meditation) and specific(cognitive-behavioral), for countering negative memes and their replication are considered, as are possibilities for memetic prevention strategies. In this book, the author outlines the roles of genes and memes in the evolution of the human brain; elucidates the creation, storage, and evolution of memes within individual brains; examines culture as a carrier and supplier of memes to the individual; provides examples of gene-meme interactions that can result in anxiety, depression, and other disorders; proposes a multiaxial gene-meme model for diagnosing mental illness; identifies areas of meme-based prevention for at-risk children; and defines specific syndromes in terms of memetic symptoms, genetic/ memetic development, and meme-based treatment.

Trinucleotide Repeat Protocols

Author : Yoshinori Kohwi
Publisher : Springer Science & Business Media
ISBN 13 : 1592598048
Total Pages : 341 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Trinucleotide Repeat Protocols by : Yoshinori Kohwi

Download or read book Trinucleotide Repeat Protocols written by Yoshinori Kohwi and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trinucleotide repeats are relatively common in the human genome. These simple repeats have received much attention since epoch-making discoveries were made that particular trinucleotide repeats are expanded in the causal genes of human hereditary neurological disorders. For example, the CGG repeat is expanded in fragile X syndrome at the 5' untranslated region (UTR) of its causal gene. In myotonic dystrophy, it is the CTG repeat that is expanded at the 3' UTR of its causal gene. The CAG repeat was also found expanded in coding regions of the genes responsible for X-linked spinal and bulbar muscular atrophy, Huntington’s disease, spinocerebellar ataxia, and other disorders. On the other hand, expansion of the GAA repeat was identified in the intron of the gene responsible for the Friedreich’s ataxia. For these trinucleotide repeat diseases, the longer the trinucleotide expansion, the earlier the age of onset and the more severe the syndrome. Thus, these findings that showed the intriguing link between a particular trinucleotide expansion and its associated neurological disorders have led to a new field of intensive study. Active research addressing the underlying mechanisms for trinucleotide repeat diseases has employed various approaches ranging from DNA biochemistry to animal models for the diseases. In particular, animal models for the triplet repeat diseases have provided excellent resources not only for understanding the mechanisms but also for exploring therapeutic interventions.

The Mental Hygiene Movement

Author : Clifford Whittingham Beers
Publisher :
ISBN 13 :
Total Pages : 104 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis The Mental Hygiene Movement by : Clifford Whittingham Beers

Download or read book The Mental Hygiene Movement written by Clifford Whittingham Beers and published by . This book was released on 1917 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Global Public Health

Author : Franklin White
Publisher : Oxford University Press
ISBN 13 : 0199751900
Total Pages : 378 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Global Public Health by : Franklin White

Download or read book Global Public Health written by Franklin White and published by Oxford University Press. This book was released on 2013-03-14 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amid ongoing shifts world economic and political systems, the promise for future public health is more tenuous than ever. Will the today's economic systems sustain tomorrow's health? Will future generations inherit fair access to health and health care? The best hope for the health of future generations is the establishment of a well-grounded, global public health system for today. To that end, Global Public Health: Ecological Foundations addresses both the challenges and cooperative solutions of contemporary public health, all within a framework of social justice, environmental sustainability, and global cooperation. With an emphasis upon ecological foundations, this text approaches public health principles-history, foundations, topics, and applications-with a community-first perspective. By achieving global reach through cooperative, local interventions, this text illustrates that through the practice of public health we can also maintain the health of our world. Blending established wisdom with new perspectives, Global Public Health will stimulate better understanding of how the different streams of public health can work more synergistically to promote global health equity. It is a foundation on which future public health measures can be built and succeed.

Assessing Genetic Risks

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309047986
Total Pages : 353 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Assessing Genetic Risks by : Institute of Medicine

Download or read book Assessing Genetic Risks written by Institute of Medicine and published by National Academies Press. This book was released on 1994-01-01 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.

Mood Genes

Author : Samuel H. Barondes
Publisher : Oxford University Press, USA
ISBN 13 : 0195131061
Total Pages : 250 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Mood Genes by : Samuel H. Barondes

Download or read book Mood Genes written by Samuel H. Barondes and published by Oxford University Press, USA. This book was released on 1999 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Mood Genes, leading psychiatrist and biological researcher Samuel B arondes answers these questions in a way that renders a complex subjec t both exciting and understandable. Focusing on manic depressive illne ss, which affects about one percent of the population and has long bee n known to run in families, Barondes describes the fascinating hunt fo r genes--called mood genes--that influence the inherited vulnerability to severe mood disorders. He builds the compelling story of this hunt on the histories of two families riddled with manic-depression, expla ining what it means to have an inherited predisposition to a severe mo od disorder, how to find the mood genes that are responsible, and what will happen as mood genes are found.

Genes, Behavior, and the Social Environment

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309101964
Total Pages : 385 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genes, Behavior, and the Social Environment by : Institute of Medicine

Download or read book Genes, Behavior, and the Social Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2006-12-07 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.