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Gene Therapy In Lung Disease
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Book Synopsis Gene Therapy in Lung Disease by : Steven M. Albeda
Download or read book Gene Therapy in Lung Disease written by Steven M. Albeda and published by CRC Press. This book was released on 2002-09-20 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents up-to-date summaries of recently completed and ongoing clinical trials. With writings from more than 35 internationally renowned experts, Gene Therapy in Lung Disease unlocks the biological mysteries of infection immunity cytokine behavior fibrosis and illustrates the use of gene the
Book Synopsis Gene Therapy for Diseases of the Lung by : Kenneth Brigham
Download or read book Gene Therapy for Diseases of the Lung written by Kenneth Brigham and published by CRC Press. This book was released on 2020-10-14 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering foreign DNA to the lungs via the airways or circulation to promising new approaches for the further development of safe and efficient gene delivery systems.
Book Synopsis Gene Therapy for Diseases of the Lung by : Kenneth Brigham
Download or read book Gene Therapy for Diseases of the Lung written by Kenneth Brigham and published by CRC Press. This book was released on 1997-04-10 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering foreign DNA to the lungs via the airways or circulation to promising new approaches for the further development of safe and efficient gene delivery systems.
Book Synopsis Cell Therapy for Lung Disease by : Julia Polak
Download or read book Cell Therapy for Lung Disease written by Julia Polak and published by World Scientific. This book was released on 2010 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The use of stem cells to help with lung regeneration and repair is a novel therapy which could help phase out the need for conventional surgical or pharmacological approaches currently employed to treat diseases of the lung or other organs. The present book explores all avenues of this new form of medical care, moving swiftly, but in depth, from the basic science of lung development, to the analyses of different stem cell types available for regeneration and on to the application of this knowledge base in initial clinical trials. In this volume a stellar group of researchers converge, from different angles, to help towards clarifying the basic mechanisms of lung repair. These range from basic concepts of regeneration and lung development, the analyses of a variety of cell types that may be involved in lung repair, to ways of creating complex lung structures, including artificial and bioartificial lungs. The book offers an insight into repair mechanisms of the diseased lung, the role of specific lung niches and provides information on initial clinical trials as well as the use of stem cells as vehicles for gene therapy. Ingenious technological aspects of assessing stem cell engraftment of stem cell bioprocessing are also included in this volume."--Publisher's website.
Book Synopsis Advances in Cell-Based and Gene-Based Therapies for Respiratory Diseases by : Miquéias Lopes-Pacheco
Download or read book Advances in Cell-Based and Gene-Based Therapies for Respiratory Diseases written by Miquéias Lopes-Pacheco and published by Frontiers Media SA. This book was released on 2022-04-29 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prof. Wagner owns stock shares in Pfizer and Merck, patent pending on whole organ decellularisation and recelluarisation US20160067378A1. The other Topic Editors declare no competing interests with regards to the Research Topic theme.
Book Synopsis Immunopharmacology by : Manzoor M. Khan
Download or read book Immunopharmacology written by Manzoor M. Khan and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.
Book Synopsis Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders by : Nicola Brunetti-Pierri
Download or read book Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders written by Nicola Brunetti-Pierri and published by Springer. This book was released on 2017-05-22 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading international experts analyze state-of-the-art advances in gene transfer vectors for applications in inherited disorders and also examine the toxicity profiles of these methods. The authors discuss the strengths and weaknesses of available vectors in the clinical setting, and specifically focus on the challenges and possible solutions that researchers are testing in order to improve the safety of gene therapy for genetic diseases. This comprehensive and authoritative overview of vector development is a necessary text for researchers, toxicologists, pharmacologists, molecular biologists, physicians, and students in these fields.
Book Synopsis Respiratory Genetics by : Edwin Silverman
Download or read book Respiratory Genetics written by Edwin Silverman and published by CRC Press. This book was released on 2005-09-30 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a recent explosion of knowledge in the field of respiratory genetics. This authoritative text brings together current knowledge in respiratory genetics in a single volume. The book includes a comprehensive introductory section to provide guidance and aid understanding of key basic concepts in respiratory genetics, including statistical methods, sample collection, bioinformatics, and functional genomics. This is followed by a series of disease-specific chapters that review epidemiology, natural history, monogenic determinants, complex disease components, disease management, and likely future developments. Respiratory Genetics is an essential reference for pulmonologists, translational researchers, and clinical geneticists, and the text will also be a useful library reference.
Book Synopsis Adenoviral Vectors for Gene Therapy by : David T. Curiel
Download or read book Adenoviral Vectors for Gene Therapy written by David T. Curiel and published by Academic Press. This book was released on 2016-03-10 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. - Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors - Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement - Demonstrates noninvasive imaging of adenovirus-mediated gene transfer - Discusses utility of adenoviral vectors in animal disease models - Considers Federal Drug Administration regulations for human clinical trials
Book Synopsis Stem Cell-Based Therapy for Lung Disease by : Janette K. Burgess
Download or read book Stem Cell-Based Therapy for Lung Disease written by Janette K. Burgess and published by Springer Nature. This book was released on 2019-11-23 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.
Book Synopsis Polyymer-based Gene Therapy for Lung Cystic Fibrosis Disease by : Bei Qiu
Download or read book Polyymer-based Gene Therapy for Lung Cystic Fibrosis Disease written by Bei Qiu and published by . This book was released on 2024 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Emerging Therapeutic Approaches for Cystic Fibrosis by : Miquéias Lopes-Pacheco
Download or read book Emerging Therapeutic Approaches for Cystic Fibrosis written by Miquéias Lopes-Pacheco and published by Frontiers Media SA. This book was released on 2020-01-27 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Clinical Relevance of Genetic Factors in Pulmonary Diseases by : Takeshi Kaneko
Download or read book Clinical Relevance of Genetic Factors in Pulmonary Diseases written by Takeshi Kaneko and published by Springer. This book was released on 2018-07-12 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the underlying genetic basis of common pulmonary diseases and discusses their pathogenesis and pathophysiology. These insights provide the basis for understanding different subtypes and phonotypes, and will promote better treatment strategies and individualized medicine. The book provides new and valuable information for the development of the areas of study, as well as practical guidelines for clinicians engaged in treating pulmonary diseases. This volume of the Respiratory Disease Series – Diagnostic Tools and Disease Managements will broaden the understanding of beginning and experienced researchers and clinicians who treat pulmonary diseases. Moreover, residents and clinicians engaged in medical oncology will find it a valuable guide to support them in their day-to-day work.
Book Synopsis Alpha-1-antitrypsin Deficiency by : Noor Kalsheker
Download or read book Alpha-1-antitrypsin Deficiency written by Noor Kalsheker and published by Academic Press. This book was released on 2017-06-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alpha-1-antitrypsin Deficiency: Biology, Diagnosis, Clinical Significance, and Emerging Therapies is the authoritative reference on AATD, providing standards for diagnosis, monitoring, treatment and appropriate avenues of research. The book covers the disease from basic biology and epidemiology, to clinical impact, and includes the understanding of the natural history of the disease and the significant advances that have been made in the last 20 years, including the three-dimensional structure of the molecule, its broad biological activity and improved therapeutic options, including replacement therapy and gene therapy. The editors have recruited international experts in the field to contribute evidence-based chapters and insights on future developments in the understanding of this disease. - Provides documentation of the variations in clinical presentation and pathology in a single reference - Presents new insights by pulling together the advances in the understanding of the structure and function of alpha1-antitrypsin deficiency with the genetic variants that cause the disease - Allows for easy reference for the diagnosis of AATD to lead to better therapeutics
Book Synopsis Molecular Basis and Gene Therapies of Cystic Fibrosis by : John Engelhardt
Download or read book Molecular Basis and Gene Therapies of Cystic Fibrosis written by John Engelhardt and published by MDPI. This book was released on 2020-12-11 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary of Genes. Thirty years ago, the gene responsible for cystic fibrosis (CF), a recessive genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator gene, was identified. This progress has considerably changed our understanding of the pathophysiology of CF and has paved the way for the development of novel and specific therapies for the disease. The CFTR gene contains 27 exons and is characterized by a frequent three base pair deletion of the p.Phe508del. As a result of collaborative work, today more than 2000 mutations have been reported in the gene, and their impact on protein function is now more evident and useful in designing new strategies to correct the gene defect. The field of gene therapy, as illustrated by Ziying Yan in this book, has worked on identifying an efficient vector system for the delivery of the wild-type CFTR gene to the lung. At the same time, animal models have been developed in mice, rats, rabbits, zebrafish, ferrets, and pigs to establish the efficacity of gene delivery. These animals are also of the utmost importance in testing new molecules as modulators or correctors to improve the CFTR lung function. During the last three decades, the epidemiology of CF has dramatically changed, as today cystic fibrosis is now a chronic adult pulmonary disease.
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Gene Therapy for Cancer by : Kelly K. Hunt
Download or read book Gene Therapy for Cancer written by Kelly K. Hunt and published by Springer Science & Business Media. This book was released on 2007-10-26 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for cancer to the clinic. This book will prove valuable as the volume of preclinical and clinical data continues to increase.
