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Author :
Publisher :
ISBN 13 :
Total Pages : 1158 pages
Book Rating : 4.:/5 ( download)
Download or read book Recent Advances in Cellular and Molecular Biology written by and published by . This book was released on 1992 with total page 1158 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Iwao Ojima
Publisher : John Wiley & Sons
ISBN 13 : 9780470744086
Total Pages : 640 pages
Book Rating : 4.7/5 (44 download)
Download or read book Fluorine in Medicinal Chemistry and Chemical Biology written by Iwao Ojima and published by John Wiley & Sons. This book was released on 2009-03-23 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: Discovery and development of fluorine containing drugs and drug candidates. New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. Structural and chemical biology of fluorinated amino acids and peptides. Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research.
Author : Padma V. Devarajan
Publisher : Springer
ISBN 13 : 3319113550
Total Pages : 788 pages
Book Rating : 4.3/5 (191 download)
Download or read book Targeted Drug Delivery : Concepts and Design written by Padma V. Devarajan and published by Springer. This book was released on 2014-12-08 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.
Author : Antony van der Ent
Publisher : Springer Nature
ISBN 13 : 3030589048
Total Pages : 482 pages
Book Rating : 4.0/5 (35 download)
Download or read book Agromining: Farming for Metals written by Antony van der Ent and published by Springer Nature. This book was released on 2020-12-07 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second and expanded edition of the first book on agromining (phytomining) presents a comprehensive overview of the metal farming & recovery of the agromining production chain. Agromining is an emerging technology that aims to transform the extraction of sources of target elements not accessible by traditional mining and processing techniques. Agromining, which is based on sustainable development, uses hyperaccumulator plants as 'metal crops' farmed on sub-economic soils or minerals wastes to obtain valuable target elements. This volume is edited and authored by the pioneers in the rapidly expanding field of agromining and presents the latest insights and developments in the field. This book provides in-depth information on the global distribution and ecology of hyperaccumulator plants, their biogeochemical pathways, the influence of rhizosphere microbes, the physiology and molecular biology of hyperaccumulation, as well as aspects of propagation and conservation of these unusual plants. It describes the agronomy of metal crops and opportunities for incorporating agromining into rehabilitation and mine closure, including test cases for agromining of nickel, cobalt, manganese, arsenic, selenium, cadmium, zinc, thallium, rare earth elements and platinum group elements. Since the first edition was published, there have successful nickel agromining field trials in the tropics (in Malaysia and Guatemala), and these are presented in a dedicated case study chapter. Other new chapters focus on the processing of bio-ore for elements other than nickel, such as rare earth elements and cadmium, and on agromining from industrial wastes such as tailings, and industrial by-products and sites. Furthermore, the book features two new chapters that provide a comprehensive assessment of accumulation a very wide range elements from the Periodic Table in various plant species around the globe, and a chapter on practical methods for discovery of hyperaccumulator plant species in the field and in the herbarium. This book is of interest to environmental professionals in the minerals industry, government regulators, and academics.
Author : David E Thurston
Publisher : Royal Society of Chemistry
ISBN 13 : 1788010779
Total Pages : 502 pages
Book Rating : 4.7/5 (88 download)
Download or read book Cytotoxic Payloads for Antibody–Drug Conjugates written by David E Thurston and published by Royal Society of Chemistry. This book was released on 2019-07-15 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody–drug conjugates (ADCs) represent one of the most promising and exciting areas of anticancer drug discovery. Five ADCs are now approved in the US and EU [i.e., ado-trastuzumab emtansine (Kadcyla™), brentuximab vedotin (Adcetris™), inotuzumab ozogamicin (Besponsa™), gemtuzumab ozogamicin (Mylotarg™) and moxetumomab pasudotox-tdfk (Lumoxiti®)] and over 70 others are in various stages of clinical development, with impressive interim results being reported for many. The technology is based on the concept of delivering a cytotoxic payload selectively to cancer cells by attaching it to an antibody targeted to antigens on the cell surfaces. This approach has several advantages including the ability to select patients as likely responders based on the presence of antigen on the surface of their cancer cells and a wider therapeutic index, given that ADC targeting enables a more efficient delivery of cytotoxic agents to cancer cells than can be achieved by conventional chemotherapy, thus minimising systemic toxicity. Although there are many examples of antibodies that have been developed for this purpose, along with numerous linker technologies used to attach the cytotoxic agent to the antibody, there is presently a relatively small number of payload molecules in clinical use. The purpose of this book is to describe the variety of payloads used to date, along with a discussion of their advantages and disadvantages and to provide information on novel payloads at the research stage that may be used clinically in the future.
Author : Rene Thom
Publisher : CRC Press
ISBN 13 : 042996157X
Total Pages : 404 pages
Book Rating : 4.4/5 (299 download)
Download or read book Structural Stability And Morphogenesis written by Rene Thom and published by CRC Press. This book was released on 2018-03-05 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 2018. Routledge is an imprint of Taylor & Francis, an Informa company.
Author : Martin Kollmar
Publisher : Humana Press
ISBN 13 : 9781493991723
Total Pages : 284 pages
Book Rating : 4.9/5 (917 download)
Download or read book Gene Prediction written by Martin Kollmar and published by Humana Press. This book was released on 2019-05-19 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces software used for gene prediction with focus on eukaryotic genomes. The chapters in this book describe software and web server usage as applied in common use-cases, and explain ways to simplify re-annotation of long available genome assemblies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary computational requirements, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Gene Prediction: Methods and Protocols is a valuable resource for researchers and research groups working on the assembly and annotation of single species or small groups of species. Chapter 3 is available open access under a CC BY 4.0 license via link.springer.com.
Author : Information Resources Management Association
Publisher : IGI Global
ISBN 13 : 146663605X
Total Pages : 1826 pages
Book Rating : 4.4/5 (666 download)
Download or read book Bioinformatics written by Information Resources Management Association and published by IGI Global. This book was released on 2013-03-31 with total page 1826 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Bioinformatics: Concepts, Methodologies, Tools, and Applications highlights the area of bioinformatics and its impact over the medical community with its innovations that change how we recognize and care for illnesses"--Provided by publisher.
Author :
Publisher :
ISBN 13 :
Total Pages : 1514 pages
Book Rating : 4.:/5 (2 download)
Download or read book Engineering News-record written by and published by . This book was released on 1922 with total page 1514 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hideo Hashizume
Publisher : Springer
ISBN 13 : 9784431569237
Total Pages : 0 pages
Book Rating : 4.5/5 (692 download)
Download or read book Natural Mineral Materials written by Hideo Hashizume and published by Springer. This book was released on 2022-07-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents natural minerals used as inorganic materials, and inorganic materials exchanging cations or anions in natural minerals for other ions not found in nature. In addition, composites such as natural mineral materials that interact with organic molecules or polymers are introduced according to how they are used. Readers can refer to this volume as a guidebook to search for specific inorganic materials, and, if they wish, can consult any part of it at random. The book will be especially helpful and of interest to both scientists and engineers.
Author : Tomohiro Kurosaki
Publisher : Springer
ISBN 13 : 3319261339
Total Pages : 233 pages
Book Rating : 4.3/5 (192 download)
Download or read book B Cell Receptor Signaling written by Tomohiro Kurosaki and published by Springer. This book was released on 2015-12-26 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Author : Jiri Jonas
Publisher : Springer Science & Business Media
ISBN 13 : 3642759262
Total Pages : 272 pages
Book Rating : 4.6/5 (427 download)
Download or read book High Pressure NMR written by Jiri Jonas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there has been a major expansion of high pressure research providing unique information about systems of interest to a wide range of scientific disciplines. Since nuclear magnetic resonance has been applied to a wide spec trum of problems in chemistry, physics and biochemistry, it is not surprising to find that high pressure NMR techniques have also had many applications in these fields of science. Clearly, the high information content of NMR experiments combined with high pressure provides a powerful tool in modern chem istry. It is the aim of this monograph, in the series on NMR Basic Principles and Progress, to illustrate the wide range of prob lems which can be successfully studied by high pressure NMR. Indeed, the various contributions in this volume discuss studies of interest to physics, chemical physics, biochemistry, and chemical reaction kinetics. In many different ways, this monograph demonstrates the power of modern experimental and theoretical techniques to investigate very complex systems. The first contribution, by D. Brinkman, deals with NMR and NQR studies of superionic conductors and high-Tc supercon ductors at high pressure. Pressure effects on phase transitions, detection of new phases, and pressure effects on diffusion and spin-lattice relaxation, represent a few of the topics discussed in this contribution of particular interest to solid state physics.
Author : Debmalya Barh
Publisher : Academic Press
ISBN 13 : 0128047496
Total Pages : 645 pages
Book Rating : 4.1/5 (28 download)
Download or read book Omics Technologies and Bio-engineering written by Debmalya Barh and published by Academic Press. This book was released on 2017-12-01 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care. - Covers various aspects of biotechnology and bio-engineering using omics technologies - Focuses on the latest developments in the field, including biofuel technologies - Provides key insights into omics approaches in personalized and precision medicine - Provides a complete picture on how one can utilize omics data in molecular biology, biotechnology and human health care
Author : Angelo Facchiano
Publisher : Frontiers Media SA
ISBN 13 : 2832544452
Total Pages : 160 pages
Book Rating : 4.8/5 (325 download)
Download or read book Artificial Intelligence and Bioinformatics Applications for Omics and Multi-Omics Studies written by Angelo Facchiano and published by Frontiers Media SA. This book was released on 2024-02-07 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lawrence Maxwell Krauss
Publisher : Simon and Schuster
ISBN 13 : 145162445X
Total Pages : 226 pages
Book Rating : 4.4/5 (516 download)
Download or read book A Universe from Nothing written by Lawrence Maxwell Krauss and published by Simon and Schuster. This book was released on 2013 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a provocative account of the astounding new answers to the most basic philosophical question: Where did the universe come from and how will it end?
Author : James Sethna
Publisher : OUP Oxford
ISBN 13 : 0191566217
Total Pages : 374 pages
Book Rating : 4.1/5 (915 download)
Download or read book Statistical Mechanics written by James Sethna and published by OUP Oxford. This book was released on 2006-04-07 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: In each generation, scientists must redefine their fields: abstracting, simplifying and distilling the previous standard topics to make room for new advances and methods. Sethna's book takes this step for statistical mechanics - a field rooted in physics and chemistry whose ideas and methods are now central to information theory, complexity, and modern biology. Aimed at advanced undergraduates and early graduate students in all of these fields, Sethna limits his main presentation to the topics that future mathematicians and biologists, as well as physicists and chemists, will find fascinating and central to their work. The amazing breadth of the field is reflected in the author's large supply of carefully crafted exercises, each an introduction to a whole field of study: everything from chaos through information theory to life at the end of the universe.
Author :
Publisher :
ISBN 13 :
Total Pages : 670 pages
Book Rating : 4.F/5 ( download)
Download or read book Landscape Architecture written by and published by . This book was released on 1996 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt:
