Future Directions In Metalloprotein And Metalloenzyme Research

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Future Directions in Metalloprotein and Metalloenzyme Research

Author : Graeme Hanson
Publisher : Springer
ISBN 13 : 3319591002
Total Pages : 191 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Future Directions in Metalloprotein and Metalloenzyme Research by : Graeme Hanson

Download or read book Future Directions in Metalloprotein and Metalloenzyme Research written by Graeme Hanson and published by Springer. This book was released on 2017-08-11 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest developments in metalloenzymes, including characterizing metal bridging in proteins and peptides, copper(II) complexes of marine peptides, high-spin Co(II) in model and metalloprotein systems to enzymes such as the molybdenum-containing enzymes, CW and pulse EPR of cytochrome P450 enzymes and the radical S-adenosylmethionine FeS family. In the previous two related volumes in the Biological Magnetic Resonance series, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine and Metals in Biology:Applications of High-Resolution EPR to Metalloenzymes, topics covered included high-resolution EPR methods, iron proteins, nickel and copper enzymes, metals in medicine, iron–sulfur cluster-containing proteins, and molybdenum enzymes. In this volume, new developments in these areas are covered in detail and new areas that have emerged are also detailed. This is an ideal book for graduate students and researchers working in the fie lds of high-resolution EPR, metalloenzymes, and metals in biology.

Metalloproteins and Metalloenzymes Roles and Mechanisms of Metals in Functional Proteins

Author : Xiangshi Tan
Publisher : World Scientific Publishing Company
ISBN 13 : 9789814635257
Total Pages : pages
Book Rating : 4.6/5 (352 download)

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Book Synopsis Metalloproteins and Metalloenzymes Roles and Mechanisms of Metals in Functional Proteins by : Xiangshi Tan

Download or read book Metalloproteins and Metalloenzymes Roles and Mechanisms of Metals in Functional Proteins written by Xiangshi Tan and published by World Scientific Publishing Company. This book was released on 2015-09-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

High Resolution EPR

Author : Graeme Hanson
Publisher : Springer Science & Business Media
ISBN 13 : 0387848568
Total Pages : 666 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis High Resolution EPR by : Graeme Hanson

Download or read book High Resolution EPR written by Graeme Hanson and published by Springer Science & Business Media. This book was released on 2009-06-19 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metalloproteins comprise approximately 30% of all known proteins, and are involved in a variety of biologically important processes, including oxygen transport, biosynthesis, electron transfer, biodegradation, drug metabolism, proteolysis, and hydrolysis of amides and esters, environmental sulfur and nitrogen cycles, and disease mechanisms. EPR spectroscopy has an important role in not only the geometric structural characterization of the redox cofactors in metalloproteins but also their electronic structure, as this is crucial for their reactivity. The advent of x-ray crystallographic snapshots of the active site redox cofactors in metalloenzymes in conjunction with high-resolution EPR spectroscopy has provided detailed structural insights into their catalytic mechanisms. This volume was conceived in 2005 at the Rocky Mountain Conference on Analytical Chemistry (EPR Symposium) to highlight the importance of high-resolution EPR spectroscopy to the structural (geometric and electronic) characterization of redox active cofactors in metalloproteins. We have been fortunate to have enlisted internationally recognized experts in this joint venture to provide the scientific community with an overview of high-resolution EPR and its application to metals in biology. This volume, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine, covers high-resolution EPR methods, iron proteins, nickel and copper enzymes, and metals in medicine. An eloquent synopsis of each chapter is provided by John Pilbrow in the Introduction. A second volume, Metals in Biology: Applications of High-Resolution EPR to Metalloenzymes, will appear later this year covering the complement of other metalloproteins. One of the pioneers in the development of pulsed EPR and its application to metalloproteins was Arthur Schweiger, whose contribution we include in this volume. Unfortunately, he passed away suddenly during the preparation of this volume. The editors and coauthors are extremely honored to dedicate this volume to the memory of Arthur Schweiger in recognition of his technical advances and insights into pulsed EPR and its application to metalloproteins. Arthur was extremely humble and treated everyone with equal respect. He was a gifted educator with an ability to explain complex phenomena in terms of simple intuitive pictures, had a delightful personality, and continues to be sadly missed by the community. It is an honor for the editors to facilitate the dissemination of these excellent contributions to the scientific community. Suggestions for future volumes are always appreciated.

Enzymes for Solving Humankind's Problems

Author : José J. G. Moura
Publisher : Springer Nature
ISBN 13 : 3030583155
Total Pages : 507 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Enzymes for Solving Humankind's Problems by : José J. G. Moura

Download or read book Enzymes for Solving Humankind's Problems written by José J. G. Moura and published by Springer Nature. This book was released on 2020-12-01 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents specific key natural and artificial systems that are promising biocatalysts in the areas of health, agriculture, environment and energy. It provides a comprehensive account of the state of the art of these systems and outlines the significant progress made in the last decade using these systems to develop innovative, sustainable and environmentally friendly solutions. Chapters from expert contributors explore how natural enzymes and artificial systems tackle specific targets such as: climate change, carbon footprint and economy and carbon dioxide utilisation; nitrogen footprint and fixation and nitrous oxide mitigation; hydrogen production, fuel cells and energy from bacteria; biomass transformation and production of added-value compounds, as well as biosensors development. This book provides an important and inspiring account for the designing of new natural and artificial systems with enhanced properties, and it appeals not only to students and researchers working in the fields of energy, health, food and environment, but also to a wider audience of educated readers that are interested in these up-to-date and exciting subjects. Chapter “Carbon Dioxide Utilisation—The Formate Route” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Chemistry of Metalloproteins

Author : Joseph J. Stephanos
Publisher : John Wiley & Sons
ISBN 13 : 1118801520
Total Pages : 500 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Chemistry of Metalloproteins by : Joseph J. Stephanos

Download or read book Chemistry of Metalloproteins written by Joseph J. Stephanos and published by John Wiley & Sons. This book was released on 2014-07-22 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the full gamut of questions in metalloprotein science Formatted as a question-and-answer guide, this book examines all major families of metal binding proteins, presenting our most current understanding of their structural, physicochemical, and functional properties. Moreover, it introduces new and emerging medical applications of metalloproteins. Readers will discover both the underlying chemistry and biology of this important area of research in bioinorganic chemistry. Chemistry of Metalloproteins features a building block approach that enables readers to master the basics and then advance to more sophisticated topics. The book begins with a general introduction to bioinorganic chemistry and metalloproteins. Next, it covers: Alkali and alkaline earth cations Metalloenzymes Copper proteins Iron proteins Vitamin B12 Chlorophyll Chapters are richly illustrated to help readers fully grasp all the chemical concepts that govern the biological action of metalloproteins. In addition, each chapter ends with a list of suggested original research articles and reviews for further investigation of individual topics. Presenting our most current understanding of metalloproteins, Chemistry of Metalloproteins is recommended for students and researchers in coordination chemistry, biology, and medicine. Each volume of the Wiley Series in Protein and Peptide Science addresses a specific facet of the field, reviewing the latest findings and presenting a broad range of perspectives. The volumes in this series constitute essential reading for biochemists, biophysicists, molecular biologists, geneticists, cell biologists, and physiologists as well as researchers in drug design and development, proteomics, and molecular medicine with an interest in proteins and peptides.

Artificial Metalloenzymes and MetalloDNAzymes in Catalysis

Author : Montserrat Diéguez
Publisher : John Wiley & Sons
ISBN 13 : 3527804072
Total Pages : 1200 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Artificial Metalloenzymes and MetalloDNAzymes in Catalysis by : Montserrat Diéguez

Download or read book Artificial Metalloenzymes and MetalloDNAzymes in Catalysis written by Montserrat Diéguez and published by John Wiley & Sons. This book was released on 2018-02-21 with total page 1200 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important reference for researchers in the field of metal-enzyme hybrid catalysis Artificial Metalloenzymes and MetalloDNAzymes in Catalysis offers a comprehensive review of the most current strategies, developed over recent decades, for the design, synthesis, and optimization of these hybrid catalysts as well as material about their application. The contributors—noted experts in the field—present information on the preparation, characterization, and optimization of artificial metalloenzymes in a timely and authoritative manner. The authors present a thorough examination of this interesting new platform for catalysis that combines the excellent selective recognition/binding properties of enzymes with transition metal catalysts. The text includes information on the various applications of metal-enzyme hybrid catalysts for novel reactions, offers insights into the latest advances in the field, and contains an informative perspective on the future: Explores the development of artificial metalloenzymes, the modern and strongly evolving research field on the verge of industrial application Contains a comprehensive reference to the research area of metal-enzyme hybrid catalysis that has experienced tremendous growth in recent years Includes contributions from leading researchers in the field Shows how this new catalysis combines the selective recognition/binding properties of enzymes with transition metal catalysts Written for catalytic chemists, bioinorganic chemists, biochemists, and organic chemists, Artificial Metalloenzymes and MetalloDNAzymes in Catalysis offers a unique reference to the fundamentals, concepts, applications, and the most recent developments for more efficient and sustainable synthesis.

Wiley Encyclopedia of Chemical Biology, Volume 3

Author : Tadhg P. Begley
Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 836 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Wiley Encyclopedia of Chemical Biology, Volume 3 by : Tadhg P. Begley

Download or read book Wiley Encyclopedia of Chemical Biology, Volume 3 written by Tadhg P. Begley and published by Wiley-Blackwell. This book was released on 2009-02-03 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

Protein Engineering

Author : Huimin Zhao
Publisher : John Wiley & Sons
ISBN 13 : 3527344705
Total Pages : 41 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Protein Engineering by : Huimin Zhao

Download or read book Protein Engineering written by Huimin Zhao and published by John Wiley & Sons. This book was released on 2021-08-23 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-stop reference that reviews protein design strategies to applications in industrial and medical biotechnology Protein Engineering: Tools and Applications is a comprehensive resource that offers a systematic and comprehensive review of the most recent advances in the field, and contains detailed information on the methodologies and strategies behind these approaches. The authors—noted experts on the topic—explore the distinctive advantages and disadvantages of the presented methodologies and strategies in a targeted and focused manner that allows for the adaptation and implementation of the strategies for new applications. The book contains information on the directed evolution, rational design, and semi-rational design of proteins and offers a review of the most recent applications in industrial and medical biotechnology. This important book: Covers technologies and methodologies used in protein engineering Includes the strategies behind the approaches, designed to help with the adaptation and implementation of these strategies for new applications Offers a comprehensive and thorough treatment of protein engineering from primary strategies to applications in industrial and medical biotechnology Presents cutting edge advances in the continuously evolving field of protein engineering Written for students and professionals of bioengineering, biotechnology, biochemistry, Protein Engineering: Tools and Applications offers an essential resource to the design strategies in protein engineering and reviews recent applications.

Uses of Inorganic Chemistry in Medicine

Author : Nicholas Farrell
Publisher : Royal Society of Chemistry
ISBN 13 : 9780854044443
Total Pages : 180 pages
Book Rating : 4.0/5 (444 download)

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Book Synopsis Uses of Inorganic Chemistry in Medicine by : Nicholas Farrell

Download or read book Uses of Inorganic Chemistry in Medicine written by Nicholas Farrell and published by Royal Society of Chemistry. This book was released on 1999 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will be an invaluable asset for many in the discipline.

Alzheimer's Disease

Author : Thimmaiah Govindaraju
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162740
Total Pages : 695 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Alzheimer's Disease by : Thimmaiah Govindaraju

Download or read book Alzheimer's Disease written by Thimmaiah Govindaraju and published by Royal Society of Chemistry. This book was released on 2022-01-04 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer's disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.

Transition Metals in Coordination Environments

Author : Ewa Broclawik
Publisher : Springer
ISBN 13 : 3030117146
Total Pages : 532 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Transition Metals in Coordination Environments by : Ewa Broclawik

Download or read book Transition Metals in Coordination Environments written by Ewa Broclawik and published by Springer. This book was released on 2019-03-16 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the electronic properties of transition metals in coordination environments. These properties are responsible for the unique and intricate activity of transition metal sites in bio- and inorganic catalysis, but also pose challenges for both theoretical and experimental studies. Written by an international group of recognized experts, the book reviews recent advances in computational modeling and discusses their interplay using experiments. It covers a broad range of topics, including advanced computational methods for transition metal systems; spectroscopic, electrochemical and catalytic properties of transition metals in coordination environments; metalloenzymes and biomimetic compounds; and spin-related phenomena. As such, the book offers an invaluable resource for all researchers and postgraduate students interested in both fundamental and application-oriented research in the field of transition metal systems.

Metalloproteomics

Author : Eugene Permyakov
Publisher : John Wiley & Sons
ISBN 13 : 9780470447741
Total Pages : 650 pages
Book Rating : 4.4/5 (477 download)

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Book Synopsis Metalloproteomics by : Eugene Permyakov

Download or read book Metalloproteomics written by Eugene Permyakov and published by John Wiley & Sons. This book was released on 2009-08-13 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesizes the current knowledge in the field and provides new insights into medical applications Metalloproteomics is the large-scale study of metal-binding proteins. These proteins, which represent about one quarter of all the proteins in the Protein Data Bank, play important roles in all biological systems and all biological processes. Metalloproteomics provides the latest information on all major families of metal-binding proteins, including their structural, physico-chemical, and functional properties, enabling readers to better understand these proteins. Moreover, the book demonstrates how understanding the structures, properties, and functions of intracellular and extracellular metal-binding proteins may unlock the key to drug development for the treatment of a myriad of diseases. Written by Eugene Permyakov, an international expert and pioneer in the structural analysis of metal-binding proteins, the book offers Theoretical introduction to cation binding Broad range of methods for investigating the binding of different cations to proteins Characteristics of interactions of physiologically important cations of Ca, Mg, Zn, Fe, Mn, Co, Cu, Ni, Mo, W, Na, and K with proteins Detailed considerations of structural and physico-chemical properties of the metal-binding proteins Interactions of all other metal cations with proteins Interactions of different types of cations with nucleic acids Throughout the text, the author integrates principles of proteomics. In addition, detailed examples underscore the role metal-binding proteins play in health and medicine. Bringing together and analyzing all the latest findings, Metalloproteomics' scope and level of insight are unparalleled. It is recommended for biophysicists, biochemists, enzymologists, cell and molecular biologists, protein and peptide scientists, organic and bioinorganic chemists, and chemical biologists.

Effects of Nanoconfinement on Catalysis

Author : Rinaldo Poli
Publisher : Springer
ISBN 13 : 3319502077
Total Pages : 266 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Effects of Nanoconfinement on Catalysis by : Rinaldo Poli

Download or read book Effects of Nanoconfinement on Catalysis written by Rinaldo Poli and published by Springer. This book was released on 2017-01-24 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the recent advances and state of the art in the use of functionalized nanostructured environments on catalysis. Nanoconfinements considered include well-defined molecular cages, imprinted self-assembled supramolecules, polymers made by living or controlled polymerization, metallorganic frameworks, carbon nanotubes, mesoporous inorganic solids, and hybrids thereof. Advantages of nanoconfinement of catalysts discussed include higher activities, improved selectivities, catalyst stabilization, cooperativity effects, simplified protocols for cascade syntheses, better catalyst recovery, and recyclability. The multiple applications that these materials offer are revolutionizing industrial sectors such as energy, electronics, sensors, biomedicine, and separation technology.

Comprehensive Asymmetric Catalysis

Author : Eric N. Jacobsen
Publisher : Springer Science & Business Media
ISBN 13 : 9783540003335
Total Pages : 258 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Comprehensive Asymmetric Catalysis by : Eric N. Jacobsen

Download or read book Comprehensive Asymmetric Catalysis written by Eric N. Jacobsen and published by Springer Science & Business Media. This book was released on 2003-09-22 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first supplement to the three volume reference work "Comprehensive Asymmetric Catalysis" critically reviews new developments to the hottest topics in the field written by recognised experts. Eleven chapters which are already in the major reference work have been supplemented and additionally five new chapters have been included. Thus the state-of-the art in this area is now re-established. Together with the basic three volume book set this supplement is not only the principal reference source for synthetic organic chemists, but also for all scientific researchers who use chiral compounds in their work (for example, in biochemical investigations and molecular medicine) as well as for pharmaceutical chemists and other industrial researchers who prepare chiral compounds.

Redox-Active Ligands

Author : Marine Desage-El Murr
Publisher : John Wiley & Sons
ISBN 13 : 3527348506
Total Pages : 373 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Redox-Active Ligands by : Marine Desage-El Murr

Download or read book Redox-Active Ligands written by Marine Desage-El Murr and published by John Wiley & Sons. This book was released on 2024-02-05 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Redox-Active Ligands Authoritative resource showcasing a new family of ligands that can lead to better catalysts and promising applications in organic synthesis Redox-Active Ligands gives a comprehensive overview of the unique features of redox-active ligands, describing their structure and synthesis, the characterization of their coordination complexes, and important applications in homogeneous catalysis. The work reflects the diversity of the subject by including ongoing research spanning coordination chemistry, organometallic chemistry, bioinspired catalysis, proton and electron transfer, and the ability of such ligands to interact with early and late transition metals, lanthanides, and actinides. The book is divided into three parts, devoted to introduction and concepts, applications, and case studies. After the introduction on key concepts related to the field, and the different types of ligands and complexes in which ligand-centered redox activity is commonly observed, mechanistic and computational studies are described. The second part focuses on catalytic applications of redox-active complexes, including examples from radical transformations, coordination chemistry and organic synthesis. Finally, case studies of redox-active guanidine ligands, and of lanthanides and actinides are presented. Other specific sample topics covered include: An overview of the electronic features of redox-active ligands, covering their historical perspective and biological background The versatility and mode of action of redox-active ligands, which sets them apart from more classic and tunable ligands such as phosphines or N-heterocyclic carbenes Preparation and catalytic applications of complexes of stable N-aryl radicals Metal complexes with redox-active ligands in H+/e- transfer transformations By providing up-to-date information on important concepts and applications, Redox-Active Ligands is an essential reading for researchers working in organometallic and coordination chemistry, catalysis, organic synthesis, and (bio)inorganic chemistry, as well as newcomers to the field.

Metal-Containing Enzymes

Author :
Publisher : Academic Press
ISBN 13 : 0128007885
Total Pages : 174 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Metal-Containing Enzymes by :

Download or read book Metal-Containing Enzymes written by and published by Academic Press. This book was released on 2014-11-24 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in metal-containing enzymes Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Biocatalysis

Author : Qayyum Husain
Publisher : Springer Nature
ISBN 13 : 3030250237
Total Pages : 341 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Biocatalysis by : Qayyum Husain

Download or read book Biocatalysis written by Qayyum Husain and published by Springer Nature. This book was released on 2019-09-03 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces readers to industrially important enzymes and discusses in detail their structures and functions, as well as their manifold applications. Due to their selective biocatalytic capabilities, enzymes are used in a broad range of industries and processes. The book highlights selected enzymes and their applications in agriculture, food processing and discoloration, as well as their role in biomedicine. In turn, it discusses biochemical engineering strategies such as enzyme immobilization, metabolic engineering, and cross-linkage of enzyme aggregates, and critically weighs their pros and cons. Offering a wealth of information, and stimulating further research by presenting new concepts on enzymatic catalytic functions in basic and applied contexts, the book represents a valuable asset for researchers from academia and industry who are engaged in biochemical engineering, microbiology and biotechnology.