Fundamentals Of Antimicrobial Pharmacokinetics And Pharmacodynamics

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Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Author : Alexander A. Vinks
Publisher : Springer Science & Business Media
ISBN 13 : 0387756132
Total Pages : 466 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics by : Alexander A. Vinks

Download or read book Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics written by Alexander A. Vinks and published by Springer Science & Business Media. This book was released on 2013-11-23 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. The book will be designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Antimicrobial Pharmacodynamics in Theory and Clinical Practice

Author : Charles H. Nightingale
Publisher : CRC Press
ISBN 13 : 1420017136
Total Pages : 536 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Antimicrobial Pharmacodynamics in Theory and Clinical Practice by : Charles H. Nightingale

Download or read book Antimicrobial Pharmacodynamics in Theory and Clinical Practice written by Charles H. Nightingale and published by CRC Press. This book was released on 2007-06-15 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking readers from the research laboratory to the bedside, this Second Edition compiles essential information on the pharmacodynamics of all major classes of the antimicrobial armamentarium including penicillins, cephalosposorins, cephamycins, carbapenems, monobactams, aminoglycosides, quinolones, macrolides, antifungals, antivirals, and emerging

The Pharmacist's Guide to Antimicrobial Therapy and Stewardship

Author : Sarah M. Wieczorkiewicz
Publisher : ASHP
ISBN 13 : 1585285218
Total Pages : 263 pages
Book Rating : 4.5/5 (852 download)

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Book Synopsis The Pharmacist's Guide to Antimicrobial Therapy and Stewardship by : Sarah M. Wieczorkiewicz

Download or read book The Pharmacist's Guide to Antimicrobial Therapy and Stewardship written by Sarah M. Wieczorkiewicz and published by ASHP. This book was released on 2015-12-15 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: When a patient comes in with a suspected infectious disease, knowledge is power. Now this knowledge is simplified, comprehensive and easy to find. The Pharmacist's Guide to Antimicrobial Therapy and Stewardship puts all the necessary information in one place, including: Evaluating potentially infected patients Identifying the infection's suspected source and related organisms Comparing the range of anti-infectives Knowing the factors that impact treatment Developing an antimicrobial stewardship program A step-wise approach walks logically from overall key concepts to disease- and drug-specific information. Disease states are summarized for easy reference. Tables make it easy to evaluate recommended treatment options. In infectious disease management, when answers are seldom black and white, this guide helps pharmacists make confident decisions.

Essentials of Antimicrobial Pharmacology

Author : Paul H. Axelsen
Publisher : Springer Science & Business Media
ISBN 13 : 1592591221
Total Pages : 127 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Essentials of Antimicrobial Pharmacology by : Paul H. Axelsen

Download or read book Essentials of Antimicrobial Pharmacology written by Paul H. Axelsen and published by Springer Science & Business Media. This book was released on 2001-09-15 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paul H. Axelsen concisely summarizes all the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrates their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. This book provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice.

Antimicrobial Pharmacodynamics in Theory and Clinical Practice

Author : Nightingale
Publisher : CRC Press
ISBN 13 : 082474182X
Total Pages : 427 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Antimicrobial Pharmacodynamics in Theory and Clinical Practice by : Nightingale

Download or read book Antimicrobial Pharmacodynamics in Theory and Clinical Practice written by Nightingale and published by CRC Press. This book was released on 2001-09-25 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-the-minute reference explores the pharmacodynamics of antimicrobials as well as the absorption, distribution, metabolism, and elimination of the major classes of antimicrobials-covering new agents such as ketolide antibiotics and highlighting the pharmacodynamic relationship between drug concentration and antimicrobial activity, as well as the relationship of pharmacodynamics to bacterial resistance. Contains specific examples and practical applications for the design of effective dosing regimens! Written by recognized experts in the field, Antimicrobial Pharmacodynamics in Theory and Clinical Practice describes the pharmacodynamic properties of all major classes of antibiotics parameters for microbiological activity of antimicrobial agents such as minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) serum/tissue protein binding and penetration rates differences between in vivo and in vitro postantibiotic effects (PAE) and more! With nearly 1000 references, tables, drawings, and illustrations, Antimicrobial Pharmacodynamics in Theory and Clinical Practice is a state-of-the-art reference for infectious disease specialists, pulmonologists, pharmacists, pharmacologists, microbiologists, biological chemists, epidemiologists, internists, and students in these disciplines.

Antibiotic Pharmacodynamics

Author : John C. Rotschafer
Publisher : Humana
ISBN 13 : 9781493933211
Total Pages : 0 pages
Book Rating : 4.9/5 (332 download)

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Book Synopsis Antibiotic Pharmacodynamics by : John C. Rotschafer

Download or read book Antibiotic Pharmacodynamics written by John C. Rotschafer and published by Humana. This book was released on 2016-03-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text offers state of the art contributions written by world renown experts which provide an extensive background on specific classes of antibiotics and summarize our understanding as to how these antibiotics might be optimally used in a clinical situation. The book explores pharmacodynamics methods for anti-infective agents, pharmacodynamics of antibacterial agents and non-antibacterial agents, as well as pharmacodynamic considerations and special populations. As part of the Methods in Pharmacology and Toxicology series, chapters include detailed insight and practical information for the lab. Comprehensive and cutting-edge, Antibiotic Pharmacodynamics serves as an ideal reference for scientists investigating advances in antibiotic pharmacodynamics now finding their way into the antibiotic development process used for licensing new antibiotics.

Fundamentals of Anaesthesia

Author : Colin Pinnock
Publisher : Cambridge University Press
ISBN 13 : 9780521690799
Total Pages : 990 pages
Book Rating : 4.6/5 (97 download)

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Book Synopsis Fundamentals of Anaesthesia by : Colin Pinnock

Download or read book Fundamentals of Anaesthesia written by Colin Pinnock and published by Cambridge University Press. This book was released on 2002-12 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.

Kucers' The Use of Antibiotics

Author : M. Lindsay Grayson
Publisher : CRC Press
ISBN 13 : 1498747965
Total Pages : 4894 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Kucers' The Use of Antibiotics by : M. Lindsay Grayson

Download or read book Kucers' The Use of Antibiotics written by M. Lindsay Grayson and published by CRC Press. This book was released on 2017-10-02 with total page 4894 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference. Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.

Anesthetic Pharmacology

Author : Alex S. Evers
Publisher : Cambridge University Press
ISBN 13 : 1139497022
Total Pages : pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Anesthetic Pharmacology by : Alex S. Evers

Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Oxford Textbook of Fundamentals of Surgery

Author : William E. G. Thomas
Publisher : Oxford University Press
ISBN 13 : 0199665540
Total Pages : 849 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Textbook of Fundamentals of Surgery by : William E. G. Thomas

Download or read book Oxford Textbook of Fundamentals of Surgery written by William E. G. Thomas and published by Oxford University Press. This book was released on 2016-07-28 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: A definitive, accessible, and reliable resource which provides a solid foundation of the knowledge and basic science needed to hone all of the core surgical skills used in surgical settings. Presented in a clear and accessible way it addresses the cross-specialty aspects of surgery applicable to all trainees.

Antibiotic Basics for Clinicians

Author : Alan R. Hauser
Publisher : Wolters kluwer india Pvt Ltd
ISBN 13 : 9389702658
Total Pages : pages
Book Rating : 4.3/5 (897 download)

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Book Synopsis Antibiotic Basics for Clinicians by : Alan R. Hauser

Download or read book Antibiotic Basics for Clinicians written by Alan R. Hauser and published by Wolters kluwer india Pvt Ltd. This book was released on 2020-04-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic Basics for Clinicians, South Asian Edition, simplifies the antibiotic selection process for the clinicians with up-to-date information on the latest and most clinically relevant antibacterial medications. This time-saving resource helps medical students master the rationale behind antibiotic selection for common

Fundamentals of Pharmacology for Children's Nurses

Author : Ian Peate
Publisher : John Wiley & Sons
ISBN 13 : 1119633230
Total Pages : 452 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Fundamentals of Pharmacology for Children's Nurses by : Ian Peate

Download or read book Fundamentals of Pharmacology for Children's Nurses written by Ian Peate and published by John Wiley & Sons. This book was released on 2021-12-01 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Registered Nurses must have thorough knowledge of pharmacology, medicines administration, and the effects of medicines. Fundamentals of Pharmacology for Children's Nurses is written for nurses and allied health professionals involved in the care of children and young people (CYP) to focus exclusively on pharmacology. Filling a gap in current literature on the subject, this much-needed resource develops the competence and confidence required to prescribe, dispense, and administer medicines to children and young people. Emphasising the importance of patient-centered care to CYP, the text describes the role of the healthcare provider working with CYP and their families; explains how to use pharmaceutical and prescribing reference guides; discusses legal and ethical issues; examines pharmacodynamics and pharmacokinetics, and more. Helping readers respond appropriately and compassionately to the needs of those receiving care and their families, this textbook: Covers a wide range of medications used in diabetes, cancer, mental health, and other areas Features a wealth of full-colour images and numerous pedagogical tools including learning objectives, self-test questions, and reflective exercises to enable readers to contextualise and assess their knowledge Presents case studies to reinforce learning, and illustrate the application of theory to practice Provides authoritative and practical guidance on formulations, adverse drug reactions, analgesics, antibiotics, immunisations, and the medications most commonly used when providing care to CYP Includes access to a companion website with interactive MCQs, case studies, references, an image bank, and links to further reading and supplemental resources Fundamentals of Pharmacology for Children's Nurses is essential reading for undergraduate children's nursing students, trainee nursing associates, those undertaking healthcare programmes of study, as well as those seeking to better understand pharmacology.

Mechanism of Action of Antieukaryotic and Antiviral Compounds

Author : Fred E. Hahn
Publisher : Springer Science & Business Media
ISBN 13 : 3642464076
Total Pages : 484 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Mechanism of Action of Antieukaryotic and Antiviral Compounds by : Fred E. Hahn

Download or read book Mechanism of Action of Antieukaryotic and Antiviral Compounds written by Fred E. Hahn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Antibiotics I was published in 1967, the teleological view was held by some that" antibiotics" were substances elaborated by certain microorgan isms for the purpose of competing with other microorganisms for survival in mixed ecological environments. However, not only had J. EHRLICH and his associates shown 15 years earlier that chloramphenicol was produced by Strepto myces venezuelae in cultures of sterilized soils but not in parallel cultures of the same soils which were not sterilized, but operationally, the search for anti cancer antibiotics was actively under way (Antibiotics I reporting on numerous such substances), although the concept of antibiosis could not logically justify such undertakings. This editor hesitates to accept the use of the term "antibiotic" for anti microbial agents of non microbiological origins which is sometimes encountered, but neither does he subscribe to the view that antibiotics are in some fundamental manner different from chemotherapeutic substances of other origins. Modes and mechanisms of action of chemotherapeutic compounds are not systematic functions of their origins nor of the taxonomical position of the target organisms. Consequently, in the selection of topics for Antibiotics III (published in 1975), synthetic drugs and natural products of higher plants (alkaloids) were represented, along with antibiotics in the strict sense of the definition. We now present Antibiotics V, for whose assembly the same selection criteria were applied as for Antibiotics Ill. The aggregate length of the contributions rendered it impractical to place the entire text between the covers of one book.

Pharmacokinetics and Pharmacodynamics of Biotech Drugs

Author : Bernd Meibohm
Publisher : John Wiley & Sons
ISBN 13 : 3527609520
Total Pages : 426 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Pharmacokinetics and Pharmacodynamics of Biotech Drugs by : Bernd Meibohm

Download or read book Pharmacokinetics and Pharmacodynamics of Biotech Drugs written by Bernd Meibohm and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first ever coverage of the pharmacokinetic and pharmacodynamic characteristics of biopharmaceuticals meets the need for a comprehensive book in this field. It spans all topics from lead identification right up to final-stage clinical trials. Following an introduction to the role of PK and PD in the development of biotech drugs, the book goes on to cover the basics, including the pharmacokinetics of peptides, monoclonal antibodies, antisense oligonucleotides, as well as viral and non-viral gene delivery vectors. The second section discusses such challenges and opportunities as pulmonary delivery of proteins and peptides, and the delivery of oligonucleotides. The final section considers the integration of PK and PD concepts into the biotech drug development plan, taking as case studies the preclinical and clinical drug development of tasidotin, as well as the examples of cetuximab and pegfilgrastim. The result is vital reading for all pharmaceutical researchers.

Basic Pharmacokinetics and Pharmacodynamics

Author : Sara E. Rosenbaum
Publisher : John Wiley & Sons
ISBN 13 : 1119143160
Total Pages : 576 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Basic Pharmacokinetics and Pharmacodynamics by : Sara E. Rosenbaum

Download or read book Basic Pharmacokinetics and Pharmacodynamics written by Sara E. Rosenbaum and published by John Wiley & Sons. This book was released on 2016-11-22 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. • Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner • Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules • Features interactive computer simulations, available online through a companion website at: https://web.uri.edu/pharmacy/research/rosenbaum/sims/ • Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications • Reviews of the 1st edition: “This is an ideal textbook for those starting out … and also for use as a reference book …." (International Society for the Study of Xenobiotics) and “I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD …. “ (British Toxicology Society Newsletter)

Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications

Author : Hartmut Derendorf
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496385896
Total Pages : 864 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications by : Hartmut Derendorf

Download or read book Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications written by Hartmut Derendorf and published by Lippincott Williams & Wilkins. This book was released on 2019-07-11 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.

Pharmacotherapeutics for Advanced Practice

Author : Virginia Poole Arcangelo
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496351843
Total Pages : 2245 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Pharmacotherapeutics for Advanced Practice by : Virginia Poole Arcangelo

Download or read book Pharmacotherapeutics for Advanced Practice written by Virginia Poole Arcangelo and published by Lippincott Williams & Wilkins. This book was released on 2016-06-09 with total page 2245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Be ready to prescribe and administer drugs safely and effectively—and grasp all the vitals of pharmacology—with the fully updated Pharmacotherapeutics for Advanced Practice, 4th edition. Written by pharmacology nursing experts, this easy-to-read text offers proven frameworks for treating more than 50 common diseases and disorders. Learn how to identify disorders, review possible therapies, then prescribe and monitor drug treatment, accurately. Based on current evidence and real-life patient scenarios, this is the perfect pharmacology learning guide and on-the-spot clinical resource. Absorb the key principles and practical methods for accurate prescribing and monitoring, with . . . NEW chapter on Parkinson’s disease, osteoarthritis, and rheumatoid arthritis NEW and updated therapies, and updated and additional case studies, with sample questions NEW content on the impacts of the Affordable Care Act Updated chapters on complementary and alternative medicine (CAM) and pharmacogenomics Updated evidence-based algorithms and drug tables – Listing uses, mechanisms, adverse effects, drug interactions, contraindications, and monitoring parameters, organized by drug class; quick access to generic and trade names and dosages Quick-scan format organizes information by body system Chapter features include: Brief overview – Pathophysiology of each disorder, and relevant classes of drugs Monitoring Patient Response section – What to monitor, and when Patient Education section – Includes information on CAM for each disorder Drug Overview tables – Usual dose, contraindications and side effects, and special considerations Algorithms – Visual cues on how to approach treatment Updated Recommended Order of Treatment tables – First-, second- and third-line drug therapies for each disorder Answers to Case Study Questions for each disorder – Strengthens critical thinking skills Selecting the Most Appropriate Agent section – The thought process for choosing an initial drug therapy Principles of Therapeutics unit – Avoiding medication errors; pharmacokinetics and pharmacodynamics; impact of drug interactions and adverse events; principles of pharmacotherapy for pediatrics, pregnancy/lactation, and geriatrics Disorders units – Pharmacotherapy for disorders in various body systems Pharmacotherapy in Health Promotion unit – Smoking cessation, immunizations, weight management Women’s Health unit – Including contraception, menopause, and osteoporosis Integrative Approach to Patient Care unit – Issues to consider when presented with more than one diagnosis Standard pharmacotherapeutics text for nurse practitioners, students, and physician assistants Ancillaries – Case Study answers, multiple choice questions and answers for every chapter, PowerPoints, Acronyms List