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Functional Characterization Of Rna Binding Protein Rbp1p And Its Interacting Proteins In Saccharomyces Cerevisiae
Download Functional Characterization Of Rna Binding Protein Rbp1p And Its Interacting Proteins In Saccharomyces Cerevisiae full books in PDF, epub, and Kindle. Read online Functional Characterization Of Rna Binding Protein Rbp1p And Its Interacting Proteins In Saccharomyces Cerevisiae ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Guide to Yeast Genetics: Functional Genomics, Proteomics, and Other Systems Analysis by :
Download or read book Guide to Yeast Genetics: Functional Genomics, Proteomics, and Other Systems Analysis written by and published by Academic Press. This book was released on 2010-02-27 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated edition of the bestselling three-part Methods in Enzymology series, Guide to Yeast Genetics and Molecular Cell Biology is specifically designed to meet the needs of graduate students, postdoctoral students, and researchers by providing all the up-to-date methods necessary to study genes in yeast. Procedures are included that enable newcomers to set up a yeast laboratory and to master basic manipulations. This volume serves as an essential reference for any beginning or experienced researcher in the field. - Provides up-to-date methods necessary to study genes in yeast - Includes proceedures that enable newcomers to set up a yeast laboratory and to master basic manipulations - Serves as an essential reference for any beginning or experienced researcher in the field
Book Synopsis Candida Albicans by : Rajendra Prasad
Download or read book Candida Albicans written by Rajendra Prasad and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Candida, which was discovered more than a century ago as a causative organism of oral thrush, is now thought to potentially infect almost every tissue of the human body. Although we still do not have a safe anti-candida drug, the growing pace of progess of research on Candida albicans holds promise that a breakthrough is imminent. Though many monographs and articles on candida and candidoses have appeared in recent years, they mostly cover the clinical aspects. This particular text, however, explains the more basic features of candida including the molecular genetics, molecular biology and immunology of the cell wall, the molecular basis of morphogenesis and the structure and function of the plasma membrane. The role of anti-candida drugs and their mechanism of action are also discussed.
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1930 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis Eukaryotic MRNA Processing by : Adrian Krainer
Download or read book Eukaryotic MRNA Processing written by Adrian Krainer and published by IRL Press. This book was released on 1997 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the major aspects of post-transcriptional mRNA processing in the nucleus of eukaryotic cells. Each of the described mRNA reactions is required for proper gene expression and can also serve as a control point for regulating the expression of many genes, for example duringembryonic development or in different cell types. The different chapters review the assembly of newly synthesized nuclear mRNA transcripts into hnRNP particles and catalytically active spliceosomes; the structure and mechanism of action of small nuclear ribonucleoprotein particles and proteinfactors that catalyse pre-mRNA splicing in mammalian cells and in yeast; the regulation of gene expression and generation of protein isoform diversity by alternative splicing; the mechanisms of 3' end cleavage and polyadenylation; the architecture of the cell nucleus in relation to these processesand to the localization of the relevant substrates and factors; the diverse mechanisms of RNA processing by ribozymes and their potential relevance for nuclear mRNA processing; the mechanism of spliced-leader addition by trans-splicing in nematodes and trypanosomes; and the process ofinsertion/deletion mRNA editing in kinetoplasmid protozoa. In each chapter, leading researchers have provided detailed, critical reviews of the history, experimental approaches, major advances, current ideas and models, as well as future directions, for each of these active areas of research.
Book Synopsis RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay by : Lynne E. Maquat
Download or read book RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay written by Lynne E. Maquat and published by Academic Press. This book was released on 2009-01-30 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. - Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway - Expert researchers introduce the most advanced technologies and techniques to identify mRNA processing, transport, localization and turnover, which are central to the process of gene expression - Offers step-by-step lab instructions, including necessary equipment and reagents
Book Synopsis The Eukaryotic RNA Exosome by : John LaCava
Download or read book The Eukaryotic RNA Exosome written by John LaCava and published by Springer Nature. This book was released on 2019-11-25 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a cross-section of RNA exosome research protocols, applied to a diversity of model organisms. Chapters guide readers through methods that e.g. delineate eukaryotic exosomes’ origins in prokaryotes, probe its RNA substrates, adapter complexes and macromolecular interaction of networks, and establish critical structural-function relationships. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, The Eukaryotic RNA Exosome: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 1996 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Functional Characterization of Ded1p, a DExD/H Box RNA Helicase, in Saccharomyces Cerevisiae by : Jean-Leon Chong
Download or read book Functional Characterization of Ded1p, a DExD/H Box RNA Helicase, in Saccharomyces Cerevisiae written by Jean-Leon Chong and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: The yeast DED1 protein (Ded1p) belongs to an evolutionarily conserved DExD/H-box protein family. Members of this family are involved in essentially all aspects of RNA metabolism, including pre-mRNA splicing, ribosomal biogenesis, RNA transport, and translation. They are often regarded as RNA helicases, or RNA unwindases, because some of them can couple ATP hydrolysis to unwinding short RNA duplexes in vitro. However, recent results suggest that, in vivo, DExD/H box proteins may dissociate specific RNA-binding proteins to remodel ribonucleoprotein complexes. Our lab previously found that Ded1p is a novel essential translation factor. However, Ded1p's mechanistic role in translation remains to be defined. To examine Ded1p's role further, I sought to identify its interacting proteins. In the first part of this dissertation (Chapter 1 to 4), I describe the unexpectedly finding that Ded1p binds to yeast L-A virus particles and accelerates the rate of L-A's negative-strand RNA synthesis in vitro. Viruses are intracellular parasites that must use the host machinery to multiply, because their genomes are very small. Thus, identification of the host factors that perform essential functions in viral replication is of crucial importance to the understanding of virus-host interactions. The findings in this dissertation and the fact that Ded1p is also required for translating the brome mosaic virus RNA2 in yeast thus raise an intriguing possibility that Ded1p is one of the key host factors favored by several evolutionarily related RNA viruses including the human hepatitis C virus. In the second part of this dissertation (Chapter 5), I show that Ded1p is associated with active spliceosomes and inactivation of Ded1p affects spliceosome formation. Moreover, data from our lab demonstrates that introns accumulate in ded1 mutant strains after being shifted to non-permissive temperature. These findings indicate that Ded1p is also involved in pre-mRNA splicing. A growing body of evidence has suggested that many proteins can function in different nuclear processes in gene expression, implying a close inter-dependent relationship among these processes. The observations in this dissertation and the fact that Ded1p is a translation factor suggest a possible intimate coordination in gene expression between the nucleus and the cytoplasm.
