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Author : Maria Pia Felli
Publisher : Frontiers Media SA
ISBN 13 : 2889719464
Total Pages : 291 pages
Book Rating : 4.8/5 (897 download)
Download or read book Targeting Developmental Pathways in Inflammation and Disease written by Maria Pia Felli and published by Frontiers Media SA. This book was released on 2022-01-05 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Selwin K. Wu
Publisher : Frontiers Media SA
ISBN 13 : 2889662179
Total Pages : 171 pages
Book Rating : 4.8/5 (896 download)
Download or read book Forces in Biology - Cell and Developmental Mechanobiology and Its Implications in Disease written by Selwin K. Wu and published by Frontiers Media SA. This book was released on 2020-12-11 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Concetta Bubici
Publisher : Frontiers Media SA
ISBN 13 : 2889630013
Total Pages : 128 pages
Book Rating : 4.8/5 (896 download)
Download or read book The Warburg Effect Regulation Under Siege: The Intertwined Pathways in Health and Disease written by Concetta Bubici and published by Frontiers Media SA. This book was released on 2019-10-17 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many cells, including immune, neuronal, cancer and stem cells, become dependent on aerobic glycolysis to escape apoptosis and accommodate their bioenergetics needs. How this metabolic change, also known as the Warburg effect, is regulated remains largely unknown. The Warburg effect has been widely investigated in cancer cells where it was first observed with the aim of decoding the molecular networks controlling its activation for therapeutic purposes. This Research Topic aimed to discuss and review all the intracellular signaling regulating the Warburg effect in cancerous and normal non-cancerous cells though original research articles, mini reviews and reviews.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309070864
Total Pages : 348 pages
Book Rating : 4.3/5 (9 download)
Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author : Rafael A. Fissore
Publisher : Frontiers Media SA
ISBN 13 : 2889459446
Total Pages : 145 pages
Book Rating : 4.8/5 (894 download)
Download or read book Molecular and Cellular Mechanisms in Reproduction and Early Development written by Rafael A. Fissore and published by Frontiers Media SA. This book was released on 2019-08-20 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Research Topic aims to support progress towards understanding the different sets of developmental processes that are absolutely required to complete all the steps essential for successful embryonic development, under physiological conditions. We sought contributions that dealt with single cells, interaction between cells as well as intra- and extracellular signal transduction. The Research Topic presents original studies covering experimental and theoretical approaches, descriptions of new methodologies, reviews and opinions.
Author : Robert A. Meyers
Publisher : Wiley-Blackwell
ISBN 13 : 9783527685905
Total Pages : 350 pages
Book Rating : 4.6/5 (859 download)
Download or read book Frontiers in Developmental Biology written by Robert A. Meyers and published by Wiley-Blackwell. This book was released on 2019-03-18 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dierk Scheel
Publisher : Oxford University Press
ISBN 13 : 9780199638796
Total Pages : 362 pages
Book Rating : 4.6/5 (387 download)
Download or read book Plant Signal Transduction written by Dierk Scheel and published by Oxford University Press. This book was released on 2002-03-28 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant growth and development is controlled by environmental cues (e.g. light, salinity) that are sensed by the plant via a variety of signal transduction pathways. This book gives an up-to-date summary of the large amount of information that is now available on the processes involved in the communication of plants with their environment.
Author : Jianfeng Feng
Publisher : Springer Science & Business Media
ISBN 13 : 1849961964
Total Pages : 411 pages
Book Rating : 4.8/5 (499 download)
Download or read book Frontiers in Computational and Systems Biology written by Jianfeng Feng and published by Springer Science & Business Media. This book was released on 2010-06-14 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological and biomedical studies have entered a new era over the past two decades thanks to the wide use of mathematical models and computational approaches. A booming of computational biology, which sheerly was a theoretician’s fantasy twenty years ago, has become a reality. Obsession with computational biology and theoretical approaches is evidenced in articles hailing the arrival of what are va- ously called quantitative biology, bioinformatics, theoretical biology, and systems biology. New technologies and data resources in genetics, such as the International HapMap project, enable large-scale studies, such as genome-wide association st- ies, which could potentially identify most common genetic variants as well as rare variants of the human DNA that may alter individual’s susceptibility to disease and the response to medical treatment. Meanwhile the multi-electrode recording from behaving animals makes it feasible to control the animal mental activity, which could potentially lead to the development of useful brain–machine interfaces. - bracing the sheer volume of genetic, genomic, and other type of data, an essential approach is, ?rst of all, to avoid drowning the true signal in the data. It has been witnessed that theoretical approach to biology has emerged as a powerful and st- ulating research paradigm in biological studies, which in turn leads to a new - search paradigm in mathematics, physics, and computer science and moves forward with the interplays among experimental studies and outcomes, simulation studies, and theoretical investigations.
Author : Takaaki Matsui
Publisher : Frontiers Media SA
ISBN 13 : 2889456943
Total Pages : 122 pages
Book Rating : 4.8/5 (894 download)
Download or read book Cell Adhesion and Migration in the Development of Multicellular Organisms written by Takaaki Matsui and published by Frontiers Media SA. This book was released on 2019-01-24 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: During development, cells are generated at specific locations within the embryo and then migrate into their destinations. At their destinations, they assemble together through cell adhesions, eventually leading to the formation of tissues and organs. In some cases, orchestration of cell adhesion and migration produces the global movement of cell groups, called collective cell migration, which is also required for the development of basic tissue structures such as spheres, clusters, and vesicles in the morphogenetic processes of development. Therefore, individual regulation and orchestration of cell adhesion and migration are quite important for appropriate tissue/organ formation during development. However, how cell adhesion and migration are regulated, and orchestrated during development? How cell adhesion and migration affects tissue formation during development? To answer these questions, we assembled several review and research articles in this eBook. By assembling these articles, we could explore the presence of core regulatory mechanisms and deepen the current understanding of cell adhesion and migration during the development of multicellular organisms.
Author : Natalie K Gordon retired
Publisher : World Scientific
ISBN 13 : 9814740691
Total Pages : 784 pages
Book Rating : 4.8/5 (147 download)
Download or read book Embryogenesis Explained written by Natalie K Gordon retired and published by World Scientific. This book was released on 2016-09-15 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: The greatest mystery of life is how a single fertilized egg develops into a fully functioning, sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory of how embryos build themselves, and combines simple physics with the most recent biochemical and genetic breakthroughs, based on the authors' prediction and then discovery of differentiation waves. They explain their ideas in a form accessible to the lay person and a broad spectrum of scientists and engineers. The diverse subjects of development, genetics and evolution, and their physics, are brought together to explain this major, previously unanswered scientific question of our time. As a follow up on The Hierarchical Genome, this book is a shorter but conceptually expanded work for the reader who is interested in science. It is useful as a starting point for the curious layman or the scientist or professional encountering the problem of embryogenesis without the formal biology background. There is also material useful for the seasoned biologist caught up in the new rush of information about the role of mechanics in developmental biology and cellular level mechanics in medicine.
Author : Simon A. Levin
Publisher : Springer Science & Business Media
ISBN 13 : 3642501249
Total Pages : 637 pages
Book Rating : 4.6/5 (425 download)
Download or read book Frontiers in Mathematical Biology written by Simon A. Levin and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: From a mathematical point of view, physiologically structured population models are an underdeveloped branch of the theory of infinite dimensional dynamical systems. We have called attention to four aspects: (i) A choice has to be made about the kind of equations one extracts from the predominantly verbal arguments about the basic assumptions, and subsequently uses as a starting point for a rigorous mathematical analysis. Though differential equations are easy to formulate (different mechanisms don't interact in infinites imal time intervals and so end up as separate terms in the equations) they may be hard to interpret rigorously as infinitesimal generators. Integral equations constitute an attractive alternative. (ii) The ability of physiologically structured population models to increase our un derstanding of the relation between mechanisms at the i-level and phenomena at the p-level will depend strongly on the development of dynamical systems lab facilities which are applicable to this class of models. (iii) Physiologically structured population models are ideally suited for the for mulation of evolutionary questions. Apart from the special case of age (see Charlesworth 1980, Yodzis 1989, Caswell 1989, and the references given there) hardly any theory exists at the moment. This will, hopefully, change rapidly in the coming years. Again the development of appropriate software may turn out to be crucial.
Author : Leonardo Reeves
Publisher : Callisto Reference
ISBN 13 : 9781641165600
Total Pages : 224 pages
Book Rating : 4.1/5 (656 download)
Download or read book New Frontiers in Developmental Biology written by Leonardo Reeves and published by Callisto Reference. This book was released on 2021-11-16 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the process through which animals and plants develop and grow is known as developmental biology. There are various aspects which are covered under developmental biology such as asexual reproduction, metamorphosis and the biology of regeneration. Some of the processes which are studied under this discipline are morphogenesis, cell differentiation and regional specification. Research in developmental biology makes use of a small number of model organisms. These non-human organisms are chosen with the aim that discoveries which are made in the study of these models will provide insights into the workings of other organisms. This book unfolds the innovative aspects of developmental biology which will be crucial for the progress of this field in the future. It presents researches and studies performed by experts across the globe. Those in search of information to further their knowledge will be greatly assisted by this book.
Author : Eumorphia Remboutsika
Publisher : Frontiers Media SA
ISBN 13 : 2889716600
Total Pages : 216 pages
Book Rating : 4.8/5 (897 download)
Download or read book Organoids as Model Systems for Human Development, Disease and Clinical Applications written by Eumorphia Remboutsika and published by Frontiers Media SA. This book was released on 2021-11-23 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Geetu Tuteja
Publisher : Frontiers Media SA
ISBN 13 : 2889719537
Total Pages : 163 pages
Book Rating : 4.8/5 (897 download)
Download or read book Multi-Omics Approaches to Study Placental Development and Disease written by Geetu Tuteja and published by Frontiers Media SA. This book was released on 2022-01-05 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert A. Meyers
Publisher : John Wiley & Sons
ISBN 13 : 352768591X
Total Pages : 837 pages
Book Rating : 4.5/5 (276 download)
Download or read book Frontiers in Developmental Biology written by Robert A. Meyers and published by John Wiley & Sons. This book was released on 2019-04-02 with total page 837 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieser aktuelle Band aus der renommierten enzyklopädischen Reihe ist der erste in vielen Jahren, der alle wichtigen Aspekte der Entwicklungsbiologie vereint, von der Morphogenese und Organogenese, über die epigenetische Regulation der Genexpression bis hin zur evolutionären Entwicklungsbiologie. Der Herausgeber hat ein herausragendes Team zusammengestellt, das diese Themen beleuchtet, und damit ein wegweisendes Werk für die kommenden Jahre geschaffen. Das Ergebnis ist ein einzigartiges, herausragendes Referenzwerk der Entwicklungsbiologie für Forscher, Studenten und Fachexperten.
Author : Colin Kleanthous
Publisher : Frontiers in Molecular Biology
ISBN 13 : 9780199637607
Total Pages : 370 pages
Book Rating : 4.6/5 (376 download)
Download or read book Protein-protein Recognition written by Colin Kleanthous and published by Frontiers in Molecular Biology. This book was released on 2000 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of Protein-Protein Recognition is to bring together concepts and systems pertaining to protein-protein interactions in a single unifying volume. In the light of the information from the genome sequencing projects and the increase in structural information it is an opportune time totry to make generalizations about how and why proteins form complexes with each other. The emphasis of the book is on heteromeric complexes (complexes in which each of the components can exist in an unbound state) and will use well-studied model systems to explain the processes of formingcomplexes. After an introductory section on the kinetics, thermodynamics, analysis, and classification of protein-protein interactions, weak, intermediate, and high affinity complexes are dealt with in turn. Weak affinity complexes are represented by electron transfer proteins and integrincomplexes. Anti-lysozyme antibodies, the MHC proteins and their interactions with T-cell receptors, and the protein interactions of eukaryotic signal transduction are the systems used to explain complexes with intermediate affinities. Finally, tight binding complexes are represented by theinteraction of protein inhibitors with serine proteases and by nuclease inhibitor complexes. Throughout the chapters common themes are the technologies which have had the greatest impact, how specificity is determined, how complexes are stabilized, and medical and industrial applications.
Author : Wenbo Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2889633454
Total Pages : 161 pages
Book Rating : 4.8/5 (896 download)
Download or read book Neuronal Development and Degeneration written by Wenbo Zhang and published by Frontiers Media SA. This book was released on 2020-01-23 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:
