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Author : Frederick R. Adler
Publisher : Frontiers Media SA
ISBN 13 : 2889746151
Total Pages : 259 pages
Book Rating : 4.8/5 (897 download)
Download or read book From Ecology to Cancer Biology and Back Again written by Frederick R. Adler and published by Frontiers Media SA. This book was released on 2022-03-08 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jason A. Somarelli
Publisher : CRC Press
ISBN 13 : 1040027687
Total Pages : 306 pages
Book Rating : 4.0/5 (4 download)
Download or read book Cancer through the Lens of Evolution and Ecology written by Jason A. Somarelli and published by CRC Press. This book was released on 2024-05-29 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer cells exist in an ever-changing “ecology” and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1) how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity; 2) how scarce resources influence cancer therapy resistance; 3) how predator-prey dynamics are mirrored in immune-cancer cross-talk; 4) how cancer cells parallel niche construction theory; 5) how changing fitness landscapes enable cancer growth; and 6) how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms. Key Features Bridges disciplines exemplifying the ways disparate fields create new perspectives when integrated. Offers insights from leading scholars in cancer biology, ecology and evolutionary biology. Provides a timely recognition by oncologists that evolutionary paradigms are crucial for breakthroughs in cancer treatment. Integrates basic and applied sciences of oncology and evolutionary biology.
Author : Beata Ujvari
Publisher : Academic Press
ISBN 13 : 0128043806
Total Pages : 290 pages
Book Rating : 4.1/5 (28 download)
Download or read book Ecology and Evolution of Cancer written by Beata Ujvari and published by Academic Press. This book was released on 2017-02-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies
Author : Athena Aktipis
Publisher : Princeton University Press
ISBN 13 : 0691163847
Total Pages : 256 pages
Book Rating : 4.6/5 (911 download)
Download or read book The Cheating Cell written by Athena Aktipis and published by Princeton University Press. This book was released on 2020-03-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer’s ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn’t mean we should give up on treating cancer—in fact, evolutionary approaches offer new and promising options for the disease’s prevention and treatments that aim at long-term management rather than simple eradication. Looking across species—from sponges and cacti to dogs and elephants—we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future—and that we cannot win a war against evolution—treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer’s fundamental nature and our relationship to it.
Author : Ubaldo E. Martinez-Outschoorn
Publisher : Frontiers Media SA
ISBN 13 : 2889631753
Total Pages : 226 pages
Book Rating : 4.8/5 (896 download)
Download or read book Cancer Ecosystems written by Ubaldo E. Martinez-Outschoorn and published by Frontiers Media SA. This book was released on 2019-11-27 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Melvyn F. Greaves
Publisher :
ISBN 13 : 9780192628343
Total Pages : 294 pages
Book Rating : 4.6/5 (283 download)
Download or read book Cancer written by Melvyn F. Greaves and published by . This book was released on 2001 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day, 1500 Americans die of cancer, and yet for most of us this deadly disease remains mysterious. Why is it so common? Why are there so many different causes? Why does treatment so often fail? What, ultimately, is cancer? In this fascinating new book, a leading cancer researcher offers general readers clear and convincing answers to these and many other questions. Mel Greaves places cancer in its evolutionary context, arguing that we can best answer the big questions about cancer by looking through a Darwinian lens. Drawing on both ancient and more modern evolutionary legacies, he shows how human development has changed the rules of evolutionary games, trapping us in a nature-nurture mismatch. Compelling examples, from the King of Naples intestinal tumor in the 15th century, through the epidemic of scrotal skin cancer in 18th-century chimney sweeps, to the current surge of cases of prostate cancer illustrate his thesis. He also shows why the old paradigms of infectious diseases or genetic disorders have proved fruitless when trying to explain this complex and elusive disease. And finally, he looks at the implications for research, prevention, and treatment of cancer that an evolutionary perspective provides. Drawing on the most recent research, this is the first book to put cancer in its evolutionary framework. At a time when Darwinian perspectives on everything from language acquisition to economics are providing new breakthroughs in understanding, medicine seems to have much to gain from the insights provided by evolutionary biology. Written in an exceptionally lucid and entertaining style, this book will be of broad interest to all those who wish to know more about this dread disease.
Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
ISBN 13 : 1439170916
Total Pages : 624 pages
Book Rating : 4.4/5 (391 download)
Download or read book The Emperor of All Maladies written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2011-08-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
Author : Raymond Francis
Publisher : Health Communications, Inc.
ISBN 13 : 075731550X
Total Pages : 386 pages
Book Rating : 4.7/5 (573 download)
Download or read book Never Fear Cancer Again written by Raymond Francis and published by Health Communications, Inc.. This book was released on 2011-08-01 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most cancer research dollars have been wasted by asking the wrong questions, looking in the wrong places, and recycling the same failed approaches while expecting different results. Conventional cancer treatments damage health, cause new cancers, lower the quality of life, and decrease the chances of survival. In fact, most people who die from cancer are not dying from cancer, but from their treatments! That's the bad news. Here's the good news: We can end the cancer epidemic. In Never Fear Cancer Again, readers will gain a revolutionary new understanding of health and disease and will come to understand that cancer is a biological process that can be turned on and off, not something that can be surgically removed or destroyed with radiation or toxic chemicals. So whether cancer has already been diagnosed or if prevention is the concern, it is possible to turn off the wayward production of these malfunctioning cells once and for all by reading this book and implementing its strategies. The key to any disease has one simple cause: malfunctioning cells that are created by either deficiency or toxicity. By switching off the malfunctioning cells, you switch off the cancer. Never Fear Cancer Again guides readers along six pathways that cause deficiency or toxicity at the cellular level: nutritional path, genetic path, medical path, toxin path, physical path, and the psychological path. By making key lifestyle changes, people truly have the power to take control of cancer and transform their health. This radically different, yet holistic approach restored author Raymond Francis back to health just as it has helped thousands of others, many of whom were told they had no other options or that their cancer was incurable. Take back your health with this book and never fear cancer again.
Author : Jeffrey Jerome Cohen
Publisher : U of Minnesota Press
ISBN 13 : 1452955751
Total Pages : 464 pages
Book Rating : 4.4/5 (529 download)
Download or read book Veer Ecology written by Jeffrey Jerome Cohen and published by U of Minnesota Press. This book was released on 2017-12-15 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The words most commonly associated with the environmental movement—save, recycle, reuse, protect, regulate, restore—describe what we can do to help the environment, but few suggest how we might transform ourselves to better navigate the sudden turns of the late Anthropocene. Which words can help us to veer conceptually along with drastic environmental flux? Jeffrey Jerome Cohen and Lowell Duckert asked thirty brilliant thinkers to each propose one verb that stresses the forceful potential of inquiry, weather, biomes, apprehensions, and desires to swerve and sheer. Each term is accompanied by a concise essay contextualizing its meaning in times of resource depletion, environmental degradation, and global climate change. Some verbs are closely tied to natural processes: compost, saturate, seep, rain, shade, sediment, vegetate, environ. Many are vaguely unsettling: drown, unmoor, obsolesce, power down, haunt. Others are enigmatic or counterintuitive: curl, globalize, commodify, ape, whirl. And while several verbs pertain to human affect and action—love, represent, behold, wait, try, attune, play, remember, decorate, tend, hope—a primary goal of Veer Ecology is to decenter the human. Indeed, each of the essays speaks to a heightened sense of possibility, awakening our imaginations and inviting us to think the world anew from radically different perspectives. A groundbreaking guide for the twenty-first century, Veer Ecology foregrounds the risks and potentialities of living on—and with—an alarmingly dynamic planet. Contributors: Stacy Alaimo, U of Texas at Arlington; Joseph Campana, Rice U; Holly Dugan, George Washington U; Lara Farina, West Virginia U; Cheryll Glotfelty, U of Nevada, Reno; Anne F. Harris, DePauw U; Tim Ingold, U of Aberdeen; Serenella Iovino, U of Turin; Stephanie LeMenager, U of Oregon; Scott Maisano, U of Massachusetts, Boston; Tobias Menely, U of California, Davis; Steve Mentz, St. John’s U; J. Allan Mitchell, U of Victoria; Timothy Morton, Rice U; Vin Nardizzi, U of British Columbia; Laura Ogden, Dartmouth College; Serpil Opperman, Hacettepe U, Ankara; Daniel C. Remein, U of Massachusetts, Boston; Margaret Ronda, U of California, Davis; Nicholas Royle, U of Sussex; Catriona Sandilands, York U; Christopher Schaberg, Loyola U; Rebecca R. Scott, U of Missouri; Theresa Shewry, U of California, Santa Barbara; Mick Smith, Queen’s U; Jesse Oak Taylor, U of Washington; Brian Thill, Golden West College; Coll Thrush, U of British Columbia, Vancouver; Cord J. Whitaker, Wellesley College; Julian Yates, U of Delaware.
Author : Azra Raza
Publisher : Basic Books
ISBN 13 : 1541699505
Total Pages : 368 pages
Book Rating : 4.5/5 (416 download)
Download or read book The First Cell written by Azra Raza and published by Basic Books. This book was released on 2019-10-15 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the fascinating scholarship of The Emperor of All Maladies and the deeply personal experience of When Breath Becomes Air, a world-class oncologist examines the current state of cancer and its devastating impact on the individuals it affects -- including herself. In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must. A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear.
Author : Çagan H. Sekercioglu
Publisher : University of Chicago Press
ISBN 13 : 022638277X
Total Pages : 398 pages
Book Rating : 4.2/5 (263 download)
Download or read book Why Birds Matter written by Çagan H. Sekercioglu and published by University of Chicago Press. This book was released on 2016-08-24 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over one hundred years, ornithologists and amateur birders have jointly campaigned for the conservation of bird species, documenting not only birds’ beauty and extraordinary diversity, but also their importance to ecosystems worldwide. But while these avian enthusiasts have noted that birds eat fruit, carrion, and pests; spread seed and fertilizer; and pollinate plants, among other services, they have rarely asked what birds are worth in economic terms. In Why Birds Matter, an international collection of ornithologists, botanists, ecologists, conservation biologists, and environmental economists seeks to quantify avian ecosystem services—the myriad benefits that birds provide to humans. The first book to approach ecosystem services from an ornithological perspective, Why Birds Matter asks what economic value we can ascribe to those services, if any, and how this value should inform conservation. Chapters explore the role of birds in such important ecological dynamics as scavenging, nutrient cycling, food chains, and plant-animal interactions—all seen through the lens of human well-being—to show that quantifying avian ecosystem services is crucial when formulating contemporary conservation strategies. Both elucidating challenges and providing examples of specific ecosystem valuations and guidance for calculation, the contributors propose that in order to advance avian conservation, we need to appeal not only to hearts and minds, but also to wallets.
Author : National Cancer Institute (U.S.)
Publisher :
ISBN 13 :
Total Pages : 96 pages
Book Rating : 4.:/5 (3 download)
Download or read book The Nation's Investment in Cancer Research written by National Cancer Institute (U.S.) and published by . This book was released on 2000 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Charles J. Krebs
Publisher : Indo American Books
ISBN 13 : 9788189617431
Total Pages : 210 pages
Book Rating : 4.6/5 (174 download)
Download or read book The Message of Ecology written by Charles J. Krebs and published by Indo American Books. This book was released on 2007 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecology Is A Fascinating Subject. This Is A Book To Introduce You To It And The Problems Ecologists Try To Analyze. Above All It Is An Attempt To Present The Subject In A Direct, Simple Form Without Including The Detail That Is Necessary In A More Conventional Textbook And Without Burdening The Subject With Abstruse Definitions Or Voluminous Statistics. So Do Not View This Book As A Text But As Supplemental Reading Designed For An Introductory Biology Course Or For A First Course In Ecology.
Author : Sundas Fayyaz
Publisher : Springer
ISBN 13 : 3319715534
Total Pages : 308 pages
Book Rating : 4.3/5 (197 download)
Download or read book Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs written by Sundas Fayyaz and published by Springer. This book was released on 2018-03-07 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics. This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.
Author : Yang Kuang
Publisher : CRC Press
ISBN 13 : 1498752977
Total Pages : 291 pages
Book Rating : 4.4/5 (987 download)
Download or read book Introduction to Mathematical Oncology written by Yang Kuang and published by CRC Press. This book was released on 2018-09-03 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.
Author : Suzanne H. Reuben
Publisher : DIANE Publishing
ISBN 13 : 1437934218
Total Pages : 240 pages
Book Rating : 4.4/5 (379 download)
Download or read book Reducing Environmental Cancer Risk written by Suzanne H. Reuben and published by DIANE Publishing. This book was released on 2010-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.
