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Free Radicals And The Liver
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Book Synopsis Free Radicals and the Liver by : Geza Csomos
Download or read book Free Radicals and the Liver written by Geza Csomos and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the results of the latest congress of the European Association for the Study of the Liver (EASL), this volume makes excellent reading since it explores in detail the role of free radical reactions in liver diseases. Studies in recent years using various methods have shown that free radicals play an important role in toxic liver disorders. For this reason, the current scientific knowledge is presented in this balanced, clinical portrayal. The account refers to the many observations, experiencesand evaluations that have been made both clinically and experimentally. Two major areas discussed concern the pathophysiological changes by free radicals and the therapeutic possibilities that have come to light.
Download or read book The Liver written by Vinood Patel and published by Academic Press. This book was released on 2018-01-03 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Liver: Oxidative Stress and Dietary Antioxidants takes a novel approach to the science of oxidative stress in liver disease by recognizing that diseases are multifactorial and oxidative stress is a single component. It highlights oxidative stress in relation to other processes, such as apoptosis, cell signaling and receptor mediated responses, and includes the therapeutic usage of natural antioxidants in the diet and food matrix, along with coverage of pharmacological and natural agents designed to counteract oxidative stress. Written for research scientists, gastroenterologists, food scientists, hepatologists and physicians, this trans-disciplinary guide will help advance medical sciences and enable new preventative and treatment strategies. Provides a framework for in-depth analysis of the basic processes of oxidative stress, from molecular biology, to whole organs in relation to the liver Bridges the trans-disciplinary divide between the basic science and mechanisms of liver disease and oxidative stress to advance medical sciences and enable preventative and treatment strategies Contains contributions from leading national and international experts, including those from world renowned institutions
Book Synopsis Free Radicals in the Pathogenesis of Liver Injury by : Giuseppe Poli
Download or read book Free Radicals in the Pathogenesis of Liver Injury written by Giuseppe Poli and published by Pergamon. This book was released on 1989 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. Since the first Congress on Free Radicals in Liver Injury took place in 1985, much research and development has taken place in this area of liver pathophysiology which is now considered to be of prime interest and importance in hepatology. In these Proceedings of the second Congress, held in Turin in June 1988, the most recent advances in the study of free radical mechanisms, from the organic to the molecular level in both acute and chronic liver injuries are discussed, in both experimental animals and man. The first section covers the remarkable advances that have been made in the clarification of biochemical mechanisms connecting oxidative insult to hepatocyte death. Stimulating new data on the role of free radicals and lipid peroxidation in the development of hepatocellular carcinoma and in liver regeneration appear in the second section. The papers in the third section investigate the involvement of oxidative species in the pathology of chr
Author :Joseph A. Knight Publisher :American Association for Clinical Chemistry, Incorporated ISBN 13 : Total Pages :404 pages Book Rating :4.E/5 ( download)
Book Synopsis Free Radicals, Antioxidants, Aging and Disease by : Joseph A. Knight
Download or read book Free Radicals, Antioxidants, Aging and Disease written by Joseph A. Knight and published by American Association for Clinical Chemistry, Incorporated. This book was released on 1999 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents information from significant peer-reviewed studies showing that increased oxidative stress has an important role in numerous medical disorders. Describes current concepts of life expectancy, the aging process, and the presence of free radicals in biological systems. Explores the relationship between free radical and increased oxidative stress in medical disorders, including atherosclerosis, ischemia/reperfusion injury, pulmonary diseases, liver and kidney disorders, cancer, and neurodegenerative disorders.
Book Synopsis Cytochromes P450 by : Costas Ioannides
Download or read book Cytochromes P450 written by Costas Ioannides and published by CRC Press. This book was released on 1996-09-06 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytochromes P450: Metabolic and Toxicological Aspects examines cytochrome P450 proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals. Studying the function of these proteins enables us to: Predict the pathways and outcome of chemical metabolism to rationalize species, sex, and age differences in toxicity Anticipate drug interactions Modify doses to fit the needs of patients Contributions from internationally acknowledged experts are organized into three sections. The first section provides an overview, the next profiles each of the cytochrome P450 families and subfamilies involved in chemical metabolism, and the last section discusses new issues and developments of current interest. This detailed and thorough examination of cytochrome P450 will be a useful source for research scientists, especially those working in the pharmaceutical industry, dealing with the safety evaluation of chemicals and the study of their metabolism, pharmacokinetics, and toxicological properties.
Book Synopsis Antioxidants in Therapy and Preventive Medicine by : Ingrid Emerit
Download or read book Antioxidants in Therapy and Preventive Medicine written by Ingrid Emerit and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty years ago, the enzyme superoxide dismutase which uses the superoxide radical anion as its specific substrate was reported. With this discovery was born a new scientific field, in which oxygen, necessary for aerobi c 1 ife on thi s planet, had to be cons i dered also in terms of its toxicity and stresses. This stimulated the search for knowledge of active oxygen species in biology and medicine. Superoxide and other reactive oxygen species are now implicated in many disease processes. Major advances have been achieved during these past years with respect to free radical generation and mechanisms of free radical action in causing tissue injury. In parallel, the possibil ity of influencing free radical related disease processes by antioxidant treatment was studied in various in vitro and in vivo systems. This was the unique theme of a conference organized in Paris by the Society for Free Radical Research (December 9-10, 1988) which brought together experts from basic sciences and clinicians in order to evaluate the current status of antioxidant therapy. The conference emphasized fundamental processes in antioxidant action. Among the major topics were superoxide dismutase (SOD) and low molecular weight substances with such activity, called SOD mimics. Other antioxidant enzymes were also considered. Antioxidant vitamins, in particular vitamins E and C, other naturally occurri ng antioxidants and vari ous synthet i c antioxidants were included in the presentations as there is now a rapidly developing series of compounds with potentially interesting clinical applications.
Book Synopsis Free Radicals in Biology and Medicine by : Barry Halliwell
Download or read book Free Radicals in Biology and Medicine written by Barry Halliwell and published by OUP Oxford. This book was released on 2015-08-21 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.
Book Synopsis Liver Pathophysiology by : Pablo Muriel
Download or read book Liver Pathophysiology written by Pablo Muriel and published by Academic Press. This book was released on 2017-03-02 with total page 917 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.
Book Synopsis Nutritional Antioxidant Therapies: Treatments and Perspectives by : Kaïs Hussain Al-Gubory
Download or read book Nutritional Antioxidant Therapies: Treatments and Perspectives written by Kaïs Hussain Al-Gubory and published by Springer. This book was released on 2018-03-10 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a collection of expert reviews on the use of plant-based antioxidant therapies in disease prevention and treatment. Topics discussed include the uses of plant and nutritional antioxidants in the contexts of reproductive health and prenatal development, healthcare and aging, noncommunicable chronic diseases, and environmental pollution. The text is complemented by a wealth of color figures and summary tables.
Book Synopsis Free Radicals: from Basic Science to Medicine by : POLI
Download or read book Free Radicals: from Basic Science to Medicine written by POLI and published by Birkhäuser. This book was released on 2013-03-11 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free radical-mediated reactions have been well known in chemistry and physical chemistry for many years. Applying this knowledge to living organisms, biochemists have shown that reactive free radicals are formed at many intracellular sites during normal metabolism, and they have started to suggest possible roles in various pathological processes and conditions, for example in radiation damage, in the metabolism of xenobiotics, in carcinogenesis and in metabolic disorders. At present, a large and relevant mass of experimental evidence supports the view that reactive free radicals are involved in the pathogenesis of several diseases and syndromes. This literature has captured the attention and interest of people involved in the biomedical field. Exciting developments in radical research are probable in the near future, establishing a greater interaction between basic science research and medicine. While the task of defining the involvement of free radicals in human pathology is difficult, it is nonetheless extremely important that such interaction be fulfilled as soon as possible. These were the considerations motivating us during the organization of the VI Biennial Meeting of the International Society for Free Radical Research held in Torino, Italy, in June 1992, and also during the preparation of this book. Experts in the various aspects of free radical research were invited to participate in the Torino Meeting and to contribute chapters for this volume.
Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash
Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Book Synopsis Antioxidants in Sport Nutrition by : Manfred Lamprecht
Download or read book Antioxidants in Sport Nutrition written by Manfred Lamprecht and published by CRC Press. This book was released on 2014-09-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Book Synopsis Free Radicals and the Liver by : Geza Csomos
Download or read book Free Radicals and the Liver written by Geza Csomos and published by Springer. This book was released on 1992-06-23 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the results of the latest congress of the European Association for the Study of the Liver (EASL), this volume makes excellent reading since it explores in detail the role of free radical reactions in liver diseases. Studies in recent years using various methods have shown that free radicals play an important role in toxic liver disorders. For this reason, the current scientific knowledge is presented in this balanced, clinical portrayal. The account refers to the many observations, experiencesand evaluations that have been made both clinically and experimentally. Two major areas discussed concern the pathophysiological changes by free radicals and the therapeutic possibilities that have come to light.
Book Synopsis Oxidants, Antioxidants And Free Radicals by : Steven Baskin
Download or read book Oxidants, Antioxidants And Free Radicals written by Steven Baskin and published by Routledge. This book was released on 2017-11-01 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collates articles investigating antioxidant, oxidant and free radical research. It examines the role of such research in health and disease, particulary with respect to developing greater understanding about the many interactions between oxidants and antioxidants, and how such substances may act as natural protectants and /or natural toxicants.
Book Synopsis Free Radicals in Medicine by : Radu Olinescu
Download or read book Free Radicals in Medicine written by Radu Olinescu and published by Nova Publishers. This book was released on 2002 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of reactive oxygen species and other free radicals in normal and disease processes has become a major area of interest in the medical scientific community. In the past 30 years, this area of study has advanced from outright rejection, to general acceptance, to intense study. While there is still some dispute as to the exact role of these highly reactive molecules in pathology, it is clear that they are present in and influence many biological processes. This book provides an overview of the possible biological effects of reactive oxygen species and other free radicals with an emphasis on pathology. The various types of free radicals that may affect the body are discussed along with the potential sources of free radicals, both internal and external to the body. The extensive defenses the body raises against the effects of these molecules in the form of enzymatic and non-enzymatic antioxidants is reviewed. A variety of conditions in which free radicals have been proposed to play a role are discussed. These include the physiological effects of oxygen stress in aging, exercise, and pregnancy. Pathologic conditions discussed include cancer, liver cirrhosis, respiratory problems, and others.
Book Synopsis Trace Elements, Micronutrients, and Free Radicals by : Ivor E. Dreosti
Download or read book Trace Elements, Micronutrients, and Free Radicals written by Ivor E. Dreosti and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses many of today's key issues pertaining to free radical damage and micronutrient production. A valuable guide for a variety of specialists concerned with nutrition and the prevention of free radical tissue injury.
Book Synopsis Liver damage due to free radicals and its antioxidant prevention: studies on liver regeneration and chemically induced hepatic prophyria by : HORVÁTH É. MÓNIKA.
Download or read book Liver damage due to free radicals and its antioxidant prevention: studies on liver regeneration and chemically induced hepatic prophyria written by HORVÁTH É. MÓNIKA. and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
