Polymeric Drugs and Drug Delivery Systems

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Author :
Publisher : CRC Press
ISBN 13 : 9781420010251
Total Pages : 332 pages
Book Rating : 4.0/5 (12 download)

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Book Synopsis Polymeric Drugs and Drug Delivery Systems by : Raphael M. Ottenbrite

Download or read book Polymeric Drugs and Drug Delivery Systems written by Raphael M. Ottenbrite and published by CRC Press. This book was released on 2019-04-30 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric materials are now playing an increasingly important role in pharmaceuticals, as well as in sensing devices, in situ prostheses and probes, and microparticle diagnostic agents. This new volume consists of twenty-two recent research-based reports on the developments in these areas of pharmaceutical and biomaterials technology. The reports w

Radicals for Life

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Publisher : Elsevier
ISBN 13 : 0080489591
Total Pages : 444 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Radicals for Life by : Ernst van Faassen

Download or read book Radicals for Life written by Ernst van Faassen and published by Elsevier. This book was released on 2011-10-13 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radicals for Life: the Various Forms of Nitric Oxide provides an up-to-date overview of the role of nitrosocompounds and nitrosyl-iron complexes in physiology. Nitrosocompounds can be considered as stabilised forms of nitric oxide, one of the most important regulatory molecules in physiology today. Many nitrosocompounds share some of the physiological functions of nitric oxide, and may be formed inside living organisms. This is the first book to be published that is dedicated to the role of such nitrosocompounds in physiology, with particular emphasis on the nitrosocompounds that are endogenously formed in higher organisms and humans. Points of discussion include: physical and chemical properties of the compounds, the main chemical pathways in vivo, as well as the physiological effects that have been recognised to date. Each of the nineteen chapters is written by distinguished specialists in the field, well known for their original and important contributions to the subject. Also included are results from a wide range of studies in vitro, in cell cultures, animal models and human volunteers. Examples of alternative forms of nitric oxide, with special emphasis on their protective role against widespread human diseases like atherosclerosis, Alzheimer's disease, diabetes, sexual dysfunction, and renal insufficiency to stroke and ischemia are also included. - First monograph to consider and provide an overview of endogenous nitrosocompounds and nitrosyl-iron complexes - Extensive bibliographic references, written by specialists of human physiology - Providing high scientific quality with a focus on implications for human diseases

Biophysics of Electron Transfer and Molecular Bioelectronics

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Publisher : Springer Science & Business Media
ISBN 13 : 1475795165
Total Pages : 200 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Biophysics of Electron Transfer and Molecular Bioelectronics by : C. Nicolini

Download or read book Biophysics of Electron Transfer and Molecular Bioelectronics written by C. Nicolini and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 1997 International Workshop on Biophysics of Electron Transfer: Fundamental Aspects and Applications, held in Bressanone, Italy, October 8-10, 1997

Yarrowia lipolytica

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Publisher : Springer Science & Business Media
ISBN 13 : 3642385834
Total Pages : 273 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Yarrowia lipolytica by : Gerold Barth

Download or read book Yarrowia lipolytica written by Gerold Barth and published by Springer Science & Business Media. This book was released on 2013-08-19 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to various special physiological features and a genome that greatly differs in structure, gene content and organization from other yeasts, Y. lipolytica is widely used as a host system. With its characteristics, such as the ability to grow on lipids or grease, to accumulate oil and the high capacity for secretion of proteases and lipases, the yeast is of great interest for biotechnological applications. The main topics covered in this Microbiology Monograph are: expression and secretion of heterologous proteins; acid and alkaline extracellular proteases; genetics, production, biochemical characterization and biotechnological application of lipases; production and secretion of several organic acids and flagrances; as well as the functional expression of P450 systems and its use in steroid biotransformation.

Water-Insoluble Drug Formulation

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Publisher : CRC Press
ISBN 13 : 1498729428
Total Pages : 736 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Water-Insoluble Drug Formulation by : Ron Liu

Download or read book Water-Insoluble Drug Formulation written by Ron Liu and published by CRC Press. This book was released on 2018-03-12 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Properties and Formulation: From Theory to Real-World Application Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone or completely derail important new drug development. Even the much-needed reformulation of currently marketed products can be significantly affected by these challenges. More recently it was reported that the percentage increased to 90% for the candidates of new chemical entities in the discovery stage and 75% for compounds under development. In the most comprehensive resource on the topic, this third edition of Water-Insoluble Drug Formulation brings together a distinguished team of experts to provide the scientific background and step-by-step guidance needed to deal with solubility issues in drug development. Twenty-three chapters systematically describe the detailed discussion on solubility theories, solubility prediction models, the aspects of preformulation, biopharmaceutics, pharmacokinetics, regulatory, and discovery support of water-insoluble drugs to various techniques used in developing delivery systems for water-insoluble drugs. This book includes more than 15 water-insoluble drug delivery systems or technologies, illustrated with case studies and featuring oral and parenteral applications. Highlighting the most current information and data available, this seminal volume reflects the significant progress that has been made in nearly all aspects of this field. The aim of this book is to provide a handy reference for pharmaceutical scientists in the handling of formulation issues related to water-insoluble drugs. In addition, this book may be useful to pharmacy and chemistry undergraduate students and pharmaceutical and biopharmaceutical graduate students to enhance their knowledge in the techniques of drug solubilization and dissolution enhancement.

Advances in Drug Delivery Systems, 6

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Author :
Publisher : Elsevier
ISBN 13 : 1483161579
Total Pages : 373 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Advances in Drug Delivery Systems, 6 by : James M. Anderson

Download or read book Advances in Drug Delivery Systems, 6 written by James M. Anderson and published by Elsevier. This book was released on 2013-10-22 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Drug Delivery Systems, 6 focuses on the progress in drug delivery systems as manifested in the fields of international pharmaceutics, polymer science, biotechnology, molecular biology, and cell biology. The selection first tackles biologically engineered microstructures and approaches to targeting bioactive compounds. Discussions focus on therapeutic efficiency of fatty acylated antiviral antibodies; effect of artificial fatty acylation on protein binding and uptake; and controlled release of proteins from lipid microcylinders. The text then elaborates on mucosal delivery of macromolecules and targeted delivery of diagnostic agents by surface-modified liposomes. The book examines the factors on in vitro micelle stability of adriamycin-block copolymer conjugates; vaginal and reproductive system treatments using a bioadhesive polymer; and control of the disposition profiles of proteins in the kidney via chemical modification. The publication also takes a look at drug delivery using biodegradable microspheres; approaches to improved antibody- and peptide-mediated targeting for imaging and therapy of cancer; and biodegradable microspheres for the delivery of oral vaccines. The selection is a valuable source material for scientists and readers interested in the advances in the systems of drug delivery.

SEC Docket

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Publisher :
ISBN 13 :
Total Pages : 960 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis SEC Docket by : United States. Securities and Exchange Commission

Download or read book SEC Docket written by United States. Securities and Exchange Commission and published by . This book was released on 1992 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Old Turkic Word Formation

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Author :
Publisher : Otto Harrassowitz Verlag
ISBN 13 : 9783447030847
Total Pages : 432 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Old Turkic Word Formation by : Marcel Erdal

Download or read book Old Turkic Word Formation written by Marcel Erdal and published by Otto Harrassowitz Verlag. This book was released on 1991 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Polymeric Systems for Drug Delivery

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Author :
Publisher : CRC Press
ISBN 13 : 9782881249471
Total Pages : 170 pages
Book Rating : 4.2/5 (494 download)

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Book Synopsis Advances in Polymeric Systems for Drug Delivery by : Raymond Bonnett

Download or read book Advances in Polymeric Systems for Drug Delivery written by Raymond Bonnett and published by CRC Press. This book was released on 2002-03-07 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title examines new drug delivery strategies utilizing intelligent polymeric materials that perform sensing, processing and response functions. The authors demonstrate the design of polymers with integrated intelligent functions to achieve site specific and temporally controlled drug delivery, specifically for pharmaceutical applications. Using stimuli-responsive polymers as molecular devices for self-regulation and externally modulated drug delivery systems are reviewed from multi-disciplinary perspectives, employing materials science and bio-engineering as an important foundation.

Flavins and Flavoproteins

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Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3111521354
Total Pages : 960 pages
Book Rating : 4.1/5 (115 download)

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Book Synopsis Flavins and Flavoproteins by : R. C. Bray

Download or read book Flavins and Flavoproteins written by R. C. Bray and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-04-01 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: To celebrate the 270th anniversary of the De Gruyter publishing house, the company is providing permanent open access to 270 selected treasures from the De Gruyter Book Archive. Titles will be made available to anyone, anywhere at any time that might be interested. The DGBA project seeks to digitize the entire backlist of titles published since 1749 to ensure that future generations have digital access to the high-quality primary sources that De Gruyter has published over the centuries.

Oncolytic Virotherapy

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Publisher : Frontiers Media SA
ISBN 13 : 2832539424
Total Pages : 213 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Oncolytic Virotherapy by : Ahmed Majeed Al-Shammari

Download or read book Oncolytic Virotherapy written by Ahmed Majeed Al-Shammari and published by Frontiers Media SA. This book was released on 2023-11-20 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using viruses to treat cancer is an established concept, and many viruses have shown promising anti-tumor efficacies. Oncolytic viruses are safe and well-characterized pathogens with a stable genome. The outstanding clinical results for oncolytic virotherapy deserve serious attention and consideration to make it a treatment option alongside classical cancer therapeutics. Virotherapy uses replication-competent oncolytic viruses to replicate and destroy cancer cells selectively. The transformed nature of cancer cells offers a permissive environment for some viruses’ replication and to complement viral mutations. The in situ amplification and spread within the tumor mass is the key benefit of such replication-competent viruses. Oncolytic virotherapy is divided into two main groups, according to tumor specificity: naturally oncolytic viruses to replicate in human cancer cells; and gene-modified viruses engineered to accomplish selective oncolysis.

Frankia Symbiosis

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Publisher : Springer Science & Business Media
ISBN 13 : 9401716013
Total Pages : 236 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Frankia Symbiosis by : P. Normand

Download or read book Frankia Symbiosis written by P. Normand and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 12th meeting on Frankia and Actinorhizal Plants that took place in Carry-le-Rouet, France in June 2001 was the opportunity for scientists to communicate about latest developments on this symbiosis that concerns a wide range of dicotyledonous plants, initiates ecological successions and is used in a number of countries to protect crops from winds or improve soil status. Selected papers on plant ecology, Frankia's genetics or physiology, and host plants' genetics or physiology are published in this special Plant & Soil issue.

Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 4431658831
Total Pages : 395 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems by : Naoya Ogata

Download or read book Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems written by Naoya Ogata and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: First of all, I would like to share the great pleasure of the successful five-day symposium with every participant in the 5th Iketani Conference which was held in Kagoshima from April1S (Tuesday) to 22 (Saturday), 1995. Outstanding speakers enthusiastically presented their up-to-the-minute results. Relatively little time was allotted for each presentation to ensure asdnuch time· as possible for intensive discussions on the particular topics that had just been p~esented: I was delighted to see that the lectures were of high quality, and the discu,ssionswere lively, exciting, and productive in a congenial atmosphere. We also had 92 papers in the poster ·session, in which young (and relatively young) scientists made every effort to present the novel results of their research in advanced biomaterials and drug delivery systems (DDS). I believe some of the research is most promising and will become noteworthy in the twenty-first century. It was a privilege for me to deliver a lecture at the special session of the symposium. In my introductory remarks, I pointed out five key terms in multifaceted biomaterials research: materials design, concept or methodology, devices, properties demanded, and fundamentals. I am confident that innovative progress in device manufacturing for end-use, e.g., artificial organs, vascular grafts, and DDS, can be brought about only through properly designed advanced materials that exhibit the desired functionality at the interface with any living body.

Chemo-Radiation-Resistance in Cancer Therapy

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Publisher : Frontiers Media SA
ISBN 13 : 288976334X
Total Pages : 393 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Chemo-Radiation-Resistance in Cancer Therapy by : Zhe-Sheng Chen

Download or read book Chemo-Radiation-Resistance in Cancer Therapy written by Zhe-Sheng Chen and published by Frontiers Media SA. This book was released on 2022-06-06 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Journal of the National Cancer Institute

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Publisher :
ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Journal of the National Cancer Institute by :

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2010 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Noncarboxylic Acids—Advances in Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464993955
Total Pages : 388 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Noncarboxylic Acids—Advances in Research and Application: 2012 Edition by :

Download or read book Noncarboxylic Acids—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Noncarboxylic Acids—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Noncarboxylic Acids. The editors have built Noncarboxylic Acids—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Noncarboxylic Acids in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Noncarboxylic Acids—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Uses of Inorganic Chemistry in Medicine

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Publisher : Royal Society of Chemistry
ISBN 13 : 1847552242
Total Pages : 174 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Uses of Inorganic Chemistry in Medicine by : Nicholas P Farrell

Download or read book Uses of Inorganic Chemistry in Medicine written by Nicholas P Farrell and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-based drugs are a commercially important sector of the pharmaceutical business, yet most bioinorganic textbooks lack the space to cover comprehensively the subject of metals in medicine. Uses of Inorganic Chemistry in Medicine approaches an understanding of the topic in a didactic and systematic manner. The field of inorganic chemistry in medicine may usefully be divided into two main categories - drugs which target metal ions in some form, whether free or protein-bound, and secondly, metal-based drugs where the central metal ion is usually the key feature of the mechanism of action. This latter category can further be subdivided into pharmacodynamic and chemotherapeutic applications, as well as those of imaging. The book summarises the chemical and biological studies on clinically used agents of lithium, gold and platinum, as well as highlighting the research on prospective new drugs, including those based on vanadium and manganese. The coverage allows a clear distinction between pharmacodynamic and therapeutic properties of metal-based drugs and focuses not only on those clinical agents in current use, but also on new drugs and uses. This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will undoubtedly be of use to senior undergraduates and postgraduates, as well as being an invaluable asset for teachers and researchers in the discipline.