Flux Of Skin

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Flux of Skin

Author : Kris Austen Radcliffe
Publisher : Six Talon Sign Fantasy & Futuristic Romance
ISBN 13 : 1939730481
Total Pages : 430 pages
Book Rating : 4.9/5 (397 download)

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Book Synopsis Flux of Skin by : Kris Austen Radcliffe

Download or read book Flux of Skin written by Kris Austen Radcliffe and published by Six Talon Sign Fantasy & Futuristic Romance. This book was released on 2017-09-05 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two millennia of battling malicious Fates, Shifters, and Burners have taken their toll. All Ladon wants is to leave his violence behind and to live a nice, quiet life with his Dragon and his beloved Rysa. We don’t always get what we want. When a vicious group of Shifters rains death down onto everyone Ladon loves, Rysa’s developing abilities turn into a raging cyclone. Her body — and his mind — rip apart. Violence edges back in. But Ladon needs to find the strength to save his family before his rupturing soul destroys everything…. Enter the explosive, genre-bending World on Fire universe where Science Fiction meets Urban Fantasy: Dragons, immortal warriors, family, love… and unknown science so advanced it’s indistinguishable from magic. Fate Fire Shifter Dragon World on Fire Series One Games of Fate Flux of Skin Fifth of Blood Bonds Broken & Silent All But Human Men and Beasts The Burning World

Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds

Author : Kenji Sugibayashi
Publisher : Springer
ISBN 13 : 4431565264
Total Pages : 428 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds by : Kenji Sugibayashi

Download or read book Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds written by Kenji Sugibayashi and published by Springer. This book was released on 2017-11-28 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews skin permeation and disposition of chemical compounds. Skin is utilized as an administration site for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Their usefulness is closely related to the permeation and disposition of entrapped active ingredients through and into the skin. Skin permeation, disposition, and metabolism of chemicals are first summarized in the general introduction. Then primary topical formulations are explained in the second part, “Basic Formulations Applied to Skin”. The explanation for the active compounds and formulations are of the most important parts required to fabricate these formulations. Skin absorption of chemicals is generally much lower than oral and the other mucosal absorptions, so that skin-penetration enhancement is a key issue to have good formulations topically applied. Part 3 presents “Skin Penetration Enhancement”. In addition, Part 4, “Selection of Topically Applied Chemical Candidates”, deals with selection methods of topically applied ingredients for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Parts 5 and 6, “Safety Assessment of Topically Applied Compounds“ and “Experimental Methods of Skin Permeation“, respectively, show safety issues and experimental methods for topical formulations. The final part consists of comments on therapeutic and cosmetic formulations by medical doctors and pharmacists. Their comments are especially helpful for pharmaceutical and cosmetic researchers who study dermatopharmacokinetics and topical formulations. This volume is particularly useful for those working in R&D, graduate students, and educators in the area of pharmaceutics, cosmetic sciences, dermatological sciences, pharmacology, toxicology, biopharmacy, pharmacokinetics, physical pharmacy, chemical engineering, and related fields.

Oxygen Transport to Tissue XXXVI

Author : Harold M. Swartz
Publisher : Springer Science & Business Media
ISBN 13 : 1493906208
Total Pages : 372 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Oxygen Transport to Tissue XXXVI by : Harold M. Swartz

Download or read book Oxygen Transport to Tissue XXXVI written by Harold M. Swartz and published by Springer Science & Business Media. This book was released on 2014-04-11 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the refereed contributions from the 41st annual meeting of ISOTT. The annual meetings of ISOTT bring together scientists from various fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. Traditionally, ISOTT conferences are a place, where an atmosphere of interaction is created, where many questions are asked after each presentation and lively discussions occur at a high scientific level. This vivid interaction is the main motivation for members to participate and gain new ideas and knowledge in the broad field of oxygen transport to tissue. The papers in this volume summarize some of the outstanding contributions from the 41st annual meeting. Special features in this volume include invited presentations from senior members of ISOTT for the theme “the wisdom of ISOTT” in which founders, past presidents and prize winners from previous meetings provided both cutting edge new knowledge and integrated overviews of critical aspects of the field. The presentations and manuscripts also include those provided by the special opportunity provided by having part of the ISOTT meeting overlap with the EPR-2013 meeting where both focused on preclinical and clinical measurements of oxygen, with a particular emphasis on cancer. Chapters 22, 24, 25 and 26 are open access under a CC BY 4.0 license via link.springer.com.

Systems of Nanovesicular Drug Delivery

Author : Amit Kumar Nayak
Publisher : Academic Press
ISBN 13 : 0323914225
Total Pages : 469 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Systems of Nanovesicular Drug Delivery by : Amit Kumar Nayak

Download or read book Systems of Nanovesicular Drug Delivery written by Amit Kumar Nayak and published by Academic Press. This book was released on 2022-07-16 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems of Nanovesicular Drug Delivery provides a thorough insight into the complete and up-to-date discussions about the preparation, properties and drug delivery applications of various nanovesicles. This volume discusses cubosomes, proniosomes and niosomes, dendrimerosomes and other new and effective approaches for drug delivery. It will be a valuable title and resource for academics and pharmaceutical scientists, including industrial pharmacists, analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailor-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource. Provides thorough insights and up-to-date discussions about the various systems of nanovesicular drug delivery Covers advanced trigger-assisted systems (such as iontophoresis, ultra-sound triggering, etc.) and how they have been used for improved drug delivery by nanovesicles Presents recent advances in drug delivery fields by global leaders and experts from academia, research, industry and regulatory agencies Includes an updated literature review of relevant key topics, good quality illustrations, chemical structures, attractive flow charts and well-organized tables

Flux of Skin

Author : Kris Austen Radcliffe
Publisher : Createspace Independent Pub
ISBN 13 : 9781502586520
Total Pages : 354 pages
Book Rating : 4.5/5 (865 download)

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Book Synopsis Flux of Skin by : Kris Austen Radcliffe

Download or read book Flux of Skin written by Kris Austen Radcliffe and published by Createspace Independent Pub. This book was released on 2014-10-04 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flux of Skin is book two of the Fate - Fire - Shifter - Dragon series and the sequel Games of Fate.Century after century, the need to do battle with malicious Fates, Shifters, and Burners always won. The world needed Ladon. So he fought. But now he's left his past, and his violence, behind. He found a new way: A quiet, modern life with his beloved Rysa.When a vicious group of Shifters rains death down onto everyone he loves, Rysa's developing abilities turn into a raging cyclone. Her body—and his mind—rip apart. Violence edges back in. But Ladon needs to find the strength to save his family before his rupturing soul destroys everything….

Advances in Heat Transfer

Author :
Publisher : Academic Press
ISBN 13 : 9780080575773
Total Pages : 470 pages
Book Rating : 4.5/5 (757 download)

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Book Synopsis Advances in Heat Transfer by :

Download or read book Advances in Heat Transfer written by and published by Academic Press. This book was released on 1993-07-22 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heat Transfer

Thermoregulation Part II

Author :
Publisher : Elsevier
ISBN 13 : 0444640754
Total Pages : 456 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Thermoregulation Part II by :

Download or read book Thermoregulation Part II written by and published by Elsevier. This book was released on 2018-11-17 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thermoregulation, Part II: From Basic Neuroscience to Clinical Neurology, Volume 155, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions. Presents a clear, logical pathway from the fundamental physiology of thermoregulation, through neurobiology, to clinical applications and disease Enables researchers and clinicians to better understand the value of temperature measurement in disease and the use of temperature as a therapy Integrates content from a broad field of research, including topics on the molecular physiology of temperature receptors, to the management of accidental hypothermia

Topical and Transdermal Drug Delivery

Author : Heather A. E. Benson
Publisher : John Wiley & Sons
ISBN 13 : 1118140494
Total Pages : 393 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Topical and Transdermal Drug Delivery by : Heather A. E. Benson

Download or read book Topical and Transdermal Drug Delivery written by Heather A. E. Benson and published by John Wiley & Sons. This book was released on 2012-02-03 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors' firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development. Topical and Transdermal Drug Delivery: Principles and Practice is divided into two parts: Part One, Current Science, Skin Permeation, and Enhancement Approaches, offers readers a fundamental understanding of the underlying science in the field. It describes the principles and techniques needed to successfully perform experimental approaches, covering such issues as skin permeation, enhancement, and assessment. Part Two, Topical and Transdermal Product Development, guides readers through the complete product development process from concept to approval, offering practical tips and cautions from experts in the field. This part also discusses regulations that are specific to the development of dermal drug products. The final chapter explores current and future trends, forecasting new development techniques and therapeutics. Throughout the book, the authors clearly set forth the basic science and experimental procedures, making it possible for researchers to design their own experimental approaches and accurately interpret their results. With contributions from experienced drug researchers, this text is highly recommended for all researchers involved in topical and transdermal product development who need to know both the state of the science and the standards of practice.

Theory and Applications of Heat Transfer in Humans, 2 Volume Set

Author : Devashish Shrivastava
Publisher : John Wiley & Sons
ISBN 13 : 1119127300
Total Pages : 897 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Theory and Applications of Heat Transfer in Humans, 2 Volume Set by : Devashish Shrivastava

Download or read book Theory and Applications of Heat Transfer in Humans, 2 Volume Set written by Devashish Shrivastava and published by John Wiley & Sons. This book was released on 2018-07-02 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative guide to theory and applications of heat transfer in humans Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author—a noted expert in the field—presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers. The book provides a basic framework that can be used to obtain ‘decent’ estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results. The book is arranged in three sections: The first section, named ‘Physics’, presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named ‘Physiology’, presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named ‘Applications’, presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow. This important text is the vital resource that: Offers a reference book in the field of heating and cooling of tissue, and associated damage. Provides a comprehensive theoretical and experimental basis with biomedical applications Shows how to develop and implement both, simple and complex mathematical models to predict tissue temperatures Includes simple examples and results so readers can use those results directly or adapt them for their applications Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage.

Man and His Thermal Environment

Author : R. P. Clark
Publisher : Hodder Education
ISBN 13 : 9780713144451
Total Pages : 253 pages
Book Rating : 4.1/5 (444 download)

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Book Synopsis Man and His Thermal Environment by : R. P. Clark

Download or read book Man and His Thermal Environment written by R. P. Clark and published by Hodder Education. This book was released on 1985 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics covered include: The thermal environment, Environmental and physiological measuring techniques, Skin temperature, Convection, Heat transfer by radiation, evaporation and conduction, Temperature and the circulation, Man is a tropical animal, Responses to cold, Perception and appreciation of the thermal environment, Clothing and The built environment.

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1440 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1990 with total page 1440 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transdermal and Intradermal Delivery of Therapeutic Agents

Author : Ajay K Banga
Publisher : CRC Press
ISBN 13 : 1439805105
Total Pages : 309 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Transdermal and Intradermal Delivery of Therapeutic Agents by : Ajay K Banga

Download or read book Transdermal and Intradermal Delivery of Therapeutic Agents written by Ajay K Banga and published by CRC Press. This book was released on 2011-05-16 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin, once thought to be an impenetrable barrier, is an extremely active organ capable of interacting with its environment. Advancements in science combined with the need for diverse drug delivery modalities have introduced a variety of transdermal and intradermal products for existing drugs at a fraction of the cost of new drug development. Commercialization of transdermal drug delivery requires technology from many disciplines beyond pharmaceutical sciences, such as polymer chemistry, adhesion sciences, mass transport, web film coating, printing, and medical technology. A comprehensive discussion of these technologies and practices, Transdermal and Intradermal Delivery of Therapeutic Agents: Application of Physical Technologies covers: Commercial development of devices and products based on transdermal physical enhancement technologies Selecting optimal enhancement technology for a specific drug molecule using case studies Physicochemical properties and practical commercial considerations related to cost, unmet clinical needs, marketing, or intellectual property protection Technologies such as microneedles, iontophoresis, electroporation, and sonophoresis, with examples for delivery of small molecules, cosmeceuticals, proteins, and vaccines Practical information on experimental procedures and challenges related to skin irritation and safety issues Up-to-date and accessible to researchers and industry experts, this book provides a comprehensive discussion of the physical approaches and practical considerations for the laboratory and marketplace.

Dermatotoxicology Methods

Author : Francis N. Marzulli
Publisher : CRC Press
ISBN 13 : 9781439805879
Total Pages : 420 pages
Book Rating : 4.8/5 (58 download)

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Book Synopsis Dermatotoxicology Methods by : Francis N. Marzulli

Download or read book Dermatotoxicology Methods written by Francis N. Marzulli and published by CRC Press. This book was released on 2019-05-07 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.

Electrical Insulation for Rotating Machines

Author : Greg C. Stone
Publisher : John Wiley & Sons
ISBN 13 : 0471682896
Total Pages : 391 pages
Book Rating : 4.4/5 (716 download)

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Book Synopsis Electrical Insulation for Rotating Machines by : Greg C. Stone

Download or read book Electrical Insulation for Rotating Machines written by Greg C. Stone and published by John Wiley & Sons. This book was released on 2004-09-21 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single comprehensive resource for the design, application, testing, and maintenance of rotating machines Filling a long-standing gap in the field, Electrical Insulation for Rotating Machines covers, in one useful volume, all aspects of the design, deterioration, testing, and repair of the electrical insulation used in motors and generators. Lucidly written by leading experts, this authoritative reference provides both historical background important to understanding machine insulation design and the most up-to-date information on new machines and how to select insulation systems for them. Coverage includes such key topics as: Types of rotating machines, windings, and rotor and stator winding construction Evaluating insulation materials and systems Stator winding and rotor winding insulation systems in current use Failure mechanisms and repair Testing and monitoring Maintenance strategies Detailing over 30 different rotor and stator winding failure processes and reviewing almost 25 different tests and monitors used to assess winding insulation condition, Electrical Insulation for Rotating Machines will help machine users avoid unnecessary machine failures, reduce maintenance costs, and inspire greater confidence in the design of future machines.

Thermal and Moisture Transport in Fibrous Materials

Author : N Pan
Publisher : Woodhead Publishing
ISBN 13 : 1845692268
Total Pages : 632 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Thermal and Moisture Transport in Fibrous Materials by : N Pan

Download or read book Thermal and Moisture Transport in Fibrous Materials written by N Pan and published by Woodhead Publishing. This book was released on 2006-10-30 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The transfer of heat and moisture through textiles is vital to the manufacture and design of clothing, technical and protective textiles. Continued advances in textile processing technology, the growth of manufactured nonwovens and the application of nanotechnology have resulted in a wealth of research in order to characterise the behaviour of these materials. Thermal and moisture transport in fibrous materials provides a comprehensive guide of the technological developments and scientific understanding in this area. The first section summarises the structure, geometry and stereology of fibrous materials. The fundamentals of wetting and its dynamics are also discussed. Part two analyses thermal and liquid interactions in textiles and offers insights into the thermodynamic behaviour of moisture as well as heat and moisture coupling. The book concludes with chapters on the human thermoregulatory system, interfacing between fibrous materials and the human body and innovative computer modelling simulations. Thermal and moisture transport in fibrous materials is an essential reference for all those involved in the textile industry, especially those concerned with the design and manufacture of technical textiles and protective clothing. Summarises the structure, geometry and stereology of fibrous materials Discusses the fundamentals of wetting and its dynamics Analyses thermal and liquid interactions in textiles

Capillary Fluid Exchange

Author : Joshua Scallan
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615040668
Total Pages : 86 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Capillary Fluid Exchange by : Joshua Scallan

Download or read book Capillary Fluid Exchange written by Joshua Scallan and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation

Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement

Author : Nina Dragicevic
Publisher : Springer
ISBN 13 : 3662450135
Total Pages : 341 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement by : Nina Dragicevic

Download or read book Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement written by Nina Dragicevic and published by Springer. This book was released on 2015-04-04 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This truly comprehensive reference, in a mini-series format with five volumes, offers a detailed description of both well-known and recently introduced methods for percutaneous penetration enhancement. The first three volumes are devoted to the broad range of chemical methods used to enhance the skin delivery of drugs, including the vast variety of chemical penetration enhancers, drug and vehicle manipulation strategies, nanocarriers, and many others. The fourth volume discusses the diverse physical methods used in penetration enhancement, such as sonophoresis, iontophoresis, electroporation, microporation, laser ablation, and microneedles. Determination of drug penetration is covered in the final volume, with a focus especially on mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. This edition of Percutaneous Penetration Enhancers will be an invaluable resource for researchers, pharmaceutical scientists, practitioners, and also students.