Molecular Biology of the Fission Yeast

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Author :
Publisher : Elsevier
ISBN 13 : 0323140068
Total Pages : 482 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Biology of the Fission Yeast by :

Download or read book Molecular Biology of the Fission Yeast written by and published by Elsevier. This book was released on 2012-12-02 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly researched yeast, which represents a system used by cell biologists, geneticists and molecular biologists, has been given only minimal coverage in the literature. Its properties make it an excellent organism for DNA and related biotechnology reseach. This book, which is the first attempt to collate existing information in one source, will be an invaluable aid to those initiating projects with this organism.

Fission Yeast

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Author :
Publisher :
ISBN 13 : 9781621820819
Total Pages : 0 pages
Book Rating : 4.8/5 (28 download)

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Book Synopsis Fission Yeast by : Iain Hagan

Download or read book Fission Yeast written by Iain Hagan and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fission yeast are unicellular, rod-shaped fungi that divide by medial fission. Studies using fission yeast were instrumental in identifying fundamental mechanisms that govern cell division, differentiation, and epigenetics, to name but a few. Their rapid growth rate, genetic malleability, and similarities to more complex eukaryotes continue to make them excellent subjects for many biochemical, molecular, and cell biological studies. This laboratory manual provides an authoritative collection of core experimental procedures that underpin modern fission yeast research. The contributors describe basic methods for culturing and genetically manipulating fission yeast, synchronization strategies for probing the cell cycle, technologies for assessing proteins, metabolites, and cell wall constituents, imaging methods to visualize subcellular structures and dynamics, and protocols for investigating chromatin and nucleic acid metabolism. Modifications to techniques commonly used in related species (e.g., budding yeast) are noted, as are useful resources for fission yeast researchers, including various databases and repositories. The well-studied fission yeast Schizosaccharomyces pombe is the focus throughout, but the emerging model S. japonicus-a larger, dimorphic species with several desirable characteristics-is also covered. This manual is an important reference for existing fission yeast laboratories and will serve as an essential start-up guide for those working with fission yeast for the first time.

The Molecular Biology of Schizosaccharomyces pombe

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662103605
Total Pages : 464 pages
Book Rating : 4.6/5 (621 download)

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Book Synopsis The Molecular Biology of Schizosaccharomyces pombe by : Richard Egel

Download or read book The Molecular Biology of Schizosaccharomyces pombe written by Richard Egel and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fission yeast Schizosaccharomyces pombe is the favoured tool of many productive research groups throughout the world, serving as a useful model for fundamental principles and mechanisms, such as genome organization, differential gene regulation, cell-cycle control, signal transduction, or cellular morphogenesis. This book collates the current state of knowledge derived from molecular studies in this simple eukaryotic microorganism. The entire sequence of its genome has been completed, emphasizing the comparative value and model status of this yeast. The individual chapters, highlighting up-to-date views on prominent aspects of molecular organization, were written by active research scientists, presenting the results of their investigations to other workers in neighbouring fields. This book intends to serve the fission yeast community as a handy source of reference for years to come. It will also be of particular value to the ever-increasing number of researchers starting to look into fission yeast affairs for comparative reasons from other platforms of molecular genetics and cell biology.

Foreign Gene Expression in Fission Yeast: Schizosaccharomyces pombe

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662034727
Total Pages : 239 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Foreign Gene Expression in Fission Yeast: Schizosaccharomyces pombe by : Yuko Giga-Hama

Download or read book Foreign Gene Expression in Fission Yeast: Schizosaccharomyces pombe written by Yuko Giga-Hama and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recombinant proteins, produced in cells or microorganisms, play an important role in basic research, medical science and the biotechnology industry. Many foreign gene expression systems using mammalian cells, E. coli, insect cells, yeast and other organisms as hosts have been developed. However, only recently has the expression system of Schizosaccharomyces pombe as a host become a subject of focus, as it is expected to be profitable for expressing foreign genes. The reason for this is that S. pombe is evolutionarily more advanced than other types of yeast. This book describes the use of S. pombe in basic research and industrial applications.

The Early Days of Yeast Genetics

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Author :
Publisher :
ISBN 13 : 9780879698744
Total Pages : 0 pages
Book Rating : 4.6/5 (987 download)

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Book Synopsis The Early Days of Yeast Genetics by : Michael N. Hall

Download or read book The Early Days of Yeast Genetics written by Michael N. Hall and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yeast genetics began with Winge's 1935 studies of S. cerevisiae in Copenhagen, and afterwards was pursued by Lindegren in the U.S. and Ephrussi in France. Genetic studies in S. pombe were pioneered by Leupold in the 1940s in Switzerland. Within four decades, not without controversies, both yeast species were recognized as essential models in eukaryotic molecular cell biology. In this remarkable volume, Hall and Linder have assembled the reminiscences of many early investigators whose pioneering studies in the years before 1975 brought yeast biology to its current maturity. These illustrated essays about the science, the events and the personalities involved capture a fascinating era, in the informal style made famous by Phage and the Origins of Molecular Biology. This is a book that all scientists interested in the development of modern genetics and molecular biology should have on their shelves.

The Rise of Yeast

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Author :
Publisher : Oxford University Press
ISBN 13 : 0190270713
Total Pages : 225 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis The Rise of Yeast by : Nicholas P. Money

Download or read book The Rise of Yeast written by Nicholas P. Money and published by Oxford University Press. This book was released on 2018 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: "[The author] argues that we cannot ascribe too much importance to yeast, and that its discovery and controlled use profoundly altered human history"--Amazon.com.

Guide to Yeast Genetics: Functional Genomics, Proteomics, and Other Systems Analysis

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Author :
Publisher : Academic Press
ISBN 13 : 9780123751737
Total Pages : 942 pages
Book Rating : 4.7/5 (517 download)

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Book Synopsis Guide to Yeast Genetics: Functional Genomics, Proteomics, and Other Systems Analysis by :

Download or read book Guide to Yeast Genetics: Functional Genomics, Proteomics, and Other Systems Analysis written by and published by Academic Press. This book was released on 2010-02-27 with total page 942 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated edition of the bestselling three-part Methods in Enzymology series, Guide to Yeast Genetics and Molecular Cell Biology is specifically designed to meet the needs of graduate students, postdoctoral students, and researchers by providing all the up-to-date methods necessary to study genes in yeast. Procedures are included that enable newcomers to set up a yeast laboratory and to master basic manipulations. This volume serves as an essential reference for any beginning or experienced researcher in the field. Provides up-to-date methods necessary to study genes in yeast. Includes proceedures that enable newcomers to set up a yeast laboratory and to master basic manipulations. This volume serves as an essential reference for any beginning or experienced researcher in the field.

Microbiology in Agriculture and Human Health

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535121448
Total Pages : 144 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Microbiology in Agriculture and Human Health by : Mohammad Manjur Shah

Download or read book Microbiology in Agriculture and Human Health written by Mohammad Manjur Shah and published by BoD – Books on Demand. This book was released on 2015-07-16 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiology involves the study of microscopic living organisms. Most of them are unicellular and all the life processes are performed by a single cell. They are associated with the health and welfare of human beings. Among the biological sciences, microbiology has established itself a place in the current century. Microorganisms also provide experimental models in various research activities, and an answer to numerous fundamental questions in genetics / metabolism, cell form and function. This book is presented in six chapters comprising of two sections. The first section deals with Microbiology and Agriculture and the second section deals with Microbiology and Human Health. The book is expected to attract wide audience from various fields of biological sciences in general, and microbiologists in particular.

Enzymes of Epigenetics

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Author :
Publisher : Elsevier
ISBN 13 : 0128119020
Total Pages : 440 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Enzymes of Epigenetics by :

Download or read book Enzymes of Epigenetics written by and published by Elsevier. This book was released on 2016-07-14 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes of Epigenetics: Part B, one of two new volumes in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods that are employed in the study of epigenetic regulation, including structural, biochemical, molecular, biological, cellular, computational, and systems approaches. Topics include chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies, and small molecule epigenetic regulators and biological connections. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Contains two new volumes that cover research methods in enzymes of epigenetics Covers such topics as chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies and small molecule epigenetic regulators, and biological connections

Fission Yeast

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Author :
Publisher :
ISBN 13 : 9781621820826
Total Pages : 0 pages
Book Rating : 4.8/5 (28 download)

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Book Synopsis Fission Yeast by : Iain Hagan

Download or read book Fission Yeast written by Iain Hagan and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fission yeast are unicellular, rod-shaped fungi that divide by medial fission. Studies using fission yeast were instrumental in identifying fundamental mechanisms that govern cell division, differentiation, and epigenetics, to name but a few. Their rapid growth rate, genetic malleability, and similarities to more complex eukaryotes continue to make them excellent subjects for many biochemical, molecular, and cell biological studies. This laboratory manual provides an authoritative collection of core experimental procedures that underpin modern fission yeast research. The contributors describe basic methods for culturing and genetically manipulating fission yeast, synchronization strategies for probing the cell cycle, technologies for assessing proteins, metabolites, and cell wall constituents, imaging methods to visualize subcellular structures and dynamics, and protocols for investigating chromatin and nucleic acid metabolism. Modifications to techniques commonly used in related species (e.g., budding yeast) are noted, as are useful resources for fission yeast researchers, including various databases and repositories. The well-studied fission yeast Schizosaccharomyces pombe is the focus throughout, but the emerging model S. japonicus-a larger, dimorphic species with several desirable characteristics-is also covered. This manual is an important reference for existing fission yeast laboratories and will serve as an essential start-up guide for those working with fission yeast for the first time.

Biological Field Emission Scanning Electron Microscopy, 2 Volume Set

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118654064
Total Pages : 741 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Biological Field Emission Scanning Electron Microscopy, 2 Volume Set by : Roland A. Fleck

Download or read book Biological Field Emission Scanning Electron Microscopy, 2 Volume Set written by Roland A. Fleck and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: The go‐to resource for microscopists on biological applications of field emission gun scanning electron microscopy (FEGSEM) The evolution of scanning electron microscopy technologies and capability over the past few years has revolutionized the biological imaging capabilities of the microscope—giving it the capability to examine surface structures of cellular membranes to reveal the organization of individual proteins across a membrane bilayer and the arrangement of cell cytoskeleton at a nm scale. Most notable are their improvements for field emission scanning electron microscopy (FEGSEM), which when combined with cryo-preparation techniques, has provided insight into a wide range of biological questions including the functionality of bacteria and viruses. This full-colour, must-have book for microscopists traces the development of the biological field emission scanning electron microscopy (FEGSEM) and highlights its current value in biological research as well as its future worth. Biological Field Emission Scanning Electron Microscopy highlights the present capability of the technique and informs the wider biological science community of its application in basic biological research. Starting with the theory and history of FEGSEM, the book offers chapters covering: operation (strengths and weakness, sample selection, handling, limitations, and preparation); Commercial developments and principals from the major FEGSEM manufacturers (Thermo Scientific, JEOL, HITACHI, ZEISS, Tescan); technical developments essential to bioFEGSEM; cryobio FEGSEM; cryo-FIB; FEGSEM digital-tomography; array tomography; public health research; mammalian cells and tissues; digital challenges (image collection, storage, and automated data analysis); and more. Examines the creation of the biological field emission gun scanning electron microscopy (FEGSEM) and discusses its benefits to the biological research community and future value Provides insight into the design and development philosophy behind current instrument manufacturers Covers sample handling, applications, and key supporting techniques Focuses on the biological applications of field emission gun scanning electron microscopy (FEGSEM), covering both plant and animal research Presented in full colour An important part of the Wiley-Royal Microscopical Series, Biological Field Emission Scanning Electron Microscopy is an ideal general resource for experienced academic and industrial users of electron microscopy—specifically, those with a need to understand the application, limitations, and strengths of FEGSEM.

Cell Cycle Checkpoint Control Protocols

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Author :
Publisher : Humana Press
ISBN 13 : 9781588291158
Total Pages : 376 pages
Book Rating : 4.2/5 (911 download)

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Book Synopsis Cell Cycle Checkpoint Control Protocols by : Howard B. Lieberman

Download or read book Cell Cycle Checkpoint Control Protocols written by Howard B. Lieberman and published by Humana Press. This book was released on 2003-11-14 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of cell cycle regulation is based on the observation that the life cycle of a cell progresses through several distinct phases, G1, M, S, and G2, occurring in a well-defined temporal order. Details of the mechanisms involved are rapidly emerging and appear extraordinarily complex. Furthermore, not only is the order of the phases important, but in normal eukaryotic cells one phase will not begin unless the prior phase is completed successfully. Che- point control mechanisms are essentially surveillance systems that monitor the events in each phase, and assure that the cell does not progress prematurely to the next phase. If conditions are such that the cell is not ready to progress—for example, because of incomplete DNA replication in S or DNA damage that may interfere with chromosome segregation in M—a transient delay in cell cycle progression will occur. Once the inducing event is properly handled— for example, DNA replication is no longer blocked or damaged DNA is repaired—cell cycle progression continues. Checkpoint controls have recently been the focus of intense study by investigators interested in mechanisms that regulate the cell cycle. Furthermore, the relationship between checkpoint c- trol and carcinogenesis has additionally enhanced interest in these cell cycle regulatory pathways. It is clear that cancer cells often lack these checkpoints and exhibit genomic instability as a result. Moreover, several tumor suppressor genes participate in checkpoint control, and alterations in these genes are as- ciated with genomic instability as well as the development of cancer.

Eukaryotic Genomic Databases

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Author :
Publisher : Humana Press
ISBN 13 : 9781493977369
Total Pages : 581 pages
Book Rating : 4.9/5 (773 download)

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Book Synopsis Eukaryotic Genomic Databases by : Martin Kollmar

Download or read book Eukaryotic Genomic Databases written by Martin Kollmar and published by Humana Press. This book was released on 2018-04-14 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores databases containing genome-based data and genome-wide analyses. This book covers databases from all eukaryotic taxa, except plants. The chapters describe database contents and classic use-cases, which assist in accessing eukaryotic genomic data and encouraging comparative genomic research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Eukaryotic Genomic Databases: Methods and Protocols is a valuable resource for geneticists and molecular biologists who are interested in the latest eukaryotic genomics data. The chapters 'PomBase: The Scientific Resource for Fission Yeast' and 'The Ensembl Genome Browser: Strategies for Accessing Eukaryotic Genome Data' are open access under a CC BY 4.0 license via link.springer.com.

Aging Research in Yeast

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Publisher : Springer Science & Business Media
ISBN 13 : 9400725612
Total Pages : 373 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Aging Research in Yeast by : Michael Breitenbach

Download or read book Aging Research in Yeast written by Michael Breitenbach and published by Springer Science & Business Media. This book was released on 2011-11-19 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined.

Cell Biology by the Numbers

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Author :
Publisher : Garland Science
ISBN 13 : 1317230698
Total Pages : 400 pages
Book Rating : 4.3/5 (172 download)

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Book Synopsis Cell Biology by the Numbers by : Ron Milo

Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Experiments with Fission Yeast

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Publisher :
ISBN 13 : 9780879694241
Total Pages : 186 pages
Book Rating : 4.6/5 (942 download)

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Book Synopsis Experiments with Fission Yeast by : Caroline Alfa

Download or read book Experiments with Fission Yeast written by Caroline Alfa and published by . This book was released on 1993-01-01 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: A lab manual based on a course at Cold Spring Harbor, in which schizosaccharomyces pombe the fission yeast, is used to investigate the genetic regulation of cell division and other aspects of cell and molecular biology. Presents 21 experiments on cell biology, classical genetics, and molecular genetics. Includes background information on the wee critters and a list of suppliers of equipment and material. No index. Plastic comb binding. Annotation copyright by Book News, Inc., Portland, OR

Structure, Function and Regulation of TOR complexes from Yeasts to Mammals

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Author :
Publisher : Academic Press
ISBN 13 : 9780123810069
Total Pages : 400 pages
Book Rating : 4.8/5 (1 download)

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Book Synopsis Structure, Function and Regulation of TOR complexes from Yeasts to Mammals by :

Download or read book Structure, Function and Regulation of TOR complexes from Yeasts to Mammals written by and published by Academic Press. This book was released on 2010-11-18 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of The Enzymes features high-caliber thematic articles on the topic of glycosylphosphatidylinositol (GPI) anchoring of proteins. Contributions from leading authorities Informs and updates on all the latest developments in the field