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Author :
Publisher :
ISBN 13 :
Total Pages : 97 pages
Book Rating : 4.:/5 (92 download)
Download or read book Feasibility and Optimization of Compact Laser-driven Beam Lines for Proton Therapy written by and published by . This book was released on 2015 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tobias Ostermayr
Publisher : Springer
ISBN 13 : 303022208X
Total Pages : 166 pages
Book Rating : 4.0/5 (32 download)
Download or read book Relativistically Intense Laser–Microplasma Interactions written by Tobias Ostermayr and published by Springer. This book was released on 2019-07-16 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation covers several important aspects of relativistically intense laser–microplasma interactions and some potential applications. A Paul-trap based target system was developed to provide fully isolated, well defined and well positioned micro-sphere-targets for experiments with focused peta-watt laser pulses. The laser interaction turned such targets into microplasmas, emitting proton beams with kinetic energies exceeding 10 MeV. The proton beam kinetic energy spectrum and spatial distribution were tuned by variation of the acceleration mechanism, reaching from broadly distributed spectra in relatively cold plasma expansions to spectra with relative energy spread as small as 20% in spherical multi-species Coulomb explosions and in directed acceleration processes. Numerical simulations and analytical calculations support these experimental findings and show how microplasmas may be used to engineer laser-driven proton sources. In a second effort, tungsten micro-needle-targets were used at a peta-watt laser to produce few-keV x-rays and 10-MeV-level proton beams simultaneously, both measured to have only few-μm effective source-size. This source was used to demonstrate single-shot simultaneous radiographic imaging with x-rays and protons of biological and technological samples. Finally, the dissertation discusses future perspectives and directions for laser–microplasma interactions including non-spherical target shapes, as well as thoughts on experimental techniques and advanced quantitative image evaluation for the laser driven radiography.
Author : Thomas Tessonnier
Publisher : Frontiers Media SA
ISBN 13 : 2889766942
Total Pages : 198 pages
Book Rating : 4.8/5 (897 download)
Download or read book Next Evolutions in Charged Particle Therapy written by Thomas Tessonnier and published by Frontiers Media SA. This book was released on 2022-08-03 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marco Durante
Publisher : Frontiers Media SA
ISBN 13 : 288945391X
Total Pages : 650 pages
Book Rating : 4.8/5 (894 download)
Download or read book Charged Particles in Oncology written by Marco Durante and published by Frontiers Media SA. This book was released on 2018-01-31 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-energy charged particles represent a cutting-edge technique in radiation oncology. Protons and carbon ions are used in several centers all over the world for the treatment of different solid tumors. Typical indications are ocular malignancies, tumors of the base of the skull, hepatocellular carcinomas and various sarcomas. The physical characteristics of the charged particles (Bragg peak) allow sparing of much more normal tissues than it is possible using conventional X-rays, and for this reason all pediatric tumors are considered eligible for protontherapy. Ions heavier than protons also display special radiobiological characteristics, which make them effective against radioresistant and hypoxic tumors. On the other hand, protons and ions with high charge (Z) and energy (HZE particles) represent a major risk for human space exploration. The main late effect of radiation exposure is cancer induction, and at the moment the dose limits for astronauts are based on cancer mortality risk. The Mars Science Laboratory (MSL) measured the dose on the route to Mars and on the planet’s surface, suggesting that a human exploration missions will exceed the radiation risk limits. Notwithstanding many studies on carcinogenesis induced by protons and heavy ions, the risk uncertainty remains very high. In this research topic we aim at gathering the experiences and opinions of scientists dealing with high-energy charged particles either for cancer treatment or for space radiation protection. Clinical results with protons and heavy ions, as well as research in medical physics and pre-clinical radiobiology are reported. In addition, ground-based and spaceflight studies on the effects of space radiation are included in this book. Particularly relevant for space studies are the clinical results on normal tissue complications and second cancers. The eBook nicely demonstrates that particle therapy in oncology and protection of astronauts from space radiation share many common topics, and can learn from each other.
Author : Harald Paganetti
Publisher : CRC Press
ISBN 13 : 1439836450
Total Pages : 691 pages
Book Rating : 4.4/5 (398 download)
Download or read book Proton Therapy Physics written by Harald Paganetti and published by CRC Press. This book was released on 2016-04-19 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.
Author : Antonio Giulietti
Publisher : Springer
ISBN 13 : 3319315633
Total Pages : 326 pages
Book Rating : 4.3/5 (193 download)
Download or read book Laser-Driven Particle Acceleration Towards Radiobiology and Medicine written by Antonio Giulietti and published by Springer. This book was released on 2016-05-04 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the new method of laser-driven acceleration for application to radiation biophysics and medicine. It provides multidisciplinary contributions from world leading scientist in order to assess the state of the art of innovative tools for radiation biology research and medical applications of ionizing radiation. The book contains insightful contributions on highly topical aspects of spatio-temporal radiation biophysics, evolving over several orders of magnitude, typically from femtosecond and sub-micrometer scales. Particular attention is devoted to the emerging technology of laser-driven particle accelerators and their application to spatio-temporal radiation biology and medical physics, customization of non-conventional and selective radiotherapy and optimized radioprotection protocols.
Author : Gerard Mourou
Publisher :
ISBN 13 : 9811217130
Total Pages : 269 pages
Book Rating : 4.8/5 (112 download)
Download or read book Beam Acceleration In Crystals And Nanostructures - Proceedings Of The Workshop written by Gerard Mourou and published by . This book was released on 2020 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309467721
Total Pages : 347 pages
Book Rating : 4.3/5 (94 download)
Download or read book Opportunities in Intense Ultrafast Lasers written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-01-31 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The laser has revolutionized many areas of science and society, providing bright and versatile light sources that transform the ways we investigate science and enables trillions of dollars of commerce. Now a second laser revolution is underway with pulsed petawatt-class lasers (1 petawatt: 1 million billion watts) that deliver nearly 100 times the total world's power concentrated into a pulse that lasts less than one-trillionth of a second. Such light sources create unique, extreme laboratory conditions that can accelerate and collide intense beams of elementary particles, drive nuclear reactions, heat matter to conditions found in stars, or even create matter out of the empty vacuum. These powerful lasers came largely from U.S. engineering, and the science and technology opportunities they enable were discussed in several previous National Academies' reports. Based on these advances, the principal research funding agencies in Europe and Asia began in the last decade to invest heavily in new facilities that will employ these high-intensity lasers for fundamental and applied science. No similar programs exist in the United States. Opportunities in Intense Ultrafast Lasers assesses the opportunities and recommends a path forward for possible U.S. investments in this area of science.
Author : Fernando Ferroni
Publisher : IOS Press
ISBN 13 : 1614991286
Total Pages : 286 pages
Book Rating : 4.6/5 (149 download)
Download or read book Laser-plasma Acceleration : Proceedings of the International School of Physics "Enrico Fermi", Varenna on Lake Como, Villa Monastero, 20-25 June 2011 written by Fernando Ferroni and published by IOS Press. This book was released on 2012 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impressive progress has been made in the field of laser-plasma acceleration in the last decade, with outstanding achievements from both experimental and theoretical viewpoints. Closely exploiting the development of ultra-intense, ultrashort pulse lasers, laser-plasma acceleration has developed rapidly, achieving accelerating gradients of the order of tens of GeV/m, and making the prospect of miniature accelerators a more realistic possibility.This book presents the lectures delivered at the Enrico Fermi International School of Physics and summer school: 'Laser-Plasma Acceleration', held in Varenna, Italy, in June 2011.
Author :
Publisher :
ISBN 13 :
Total Pages : 1720 pages
Book Rating : 4.:/5 (3 download)
Download or read book Government Reports Annual Index written by and published by . This book was released on 1992 with total page 1720 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael C. Joiner
Publisher : CRC Press
ISBN 13 : 0429955405
Total Pages : 361 pages
Book Rating : 4.4/5 (299 download)
Download or read book Basic Clinical Radiobiology written by Michael C. Joiner and published by CRC Press. This book was released on 2018-08-28 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Builds on success and reputation of previous editions Draws on the considerable teaching experience of an international author team, most notably the US and European Editors The gold-standard European text for training, adopted by ESTRO as a course book, as a text for the Royal College of Radiologists' radiobiology exam and by courses in the US Highly illustrated with new, 2 colour illustrations Clear and concise style, appropriate for trainees and also practising radiation oncologists requiring a ready reference to the subject Includes new chapters on stem cells, tissue response and the meeting point of meeting point of radiotherapy, radiobiology and physics
Author : Michael Goitein
Publisher : Springer Science & Business Media
ISBN 13 : 0387726454
Total Pages : 333 pages
Book Rating : 4.3/5 (877 download)
Download or read book Radiation Oncology: A Physicist's-Eye View written by Michael Goitein and published by Springer Science & Business Media. This book was released on 2007-08-14 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers collected in this hugely useful volume cover the principle physical and biological aspects of radiation therapy and in addition, address practical clinical considerations in the planning and delivering of that therapy. The importance of the assessment of uncertainties is emphasized. Topics include an overview of the physics of the interactions of radiation with matter and the definition of the goals and the design of radiation therapy approaches.
Author : Stephen Myers
Publisher : Springer Nature
ISBN 13 : 303034245X
Total Pages : 867 pages
Book Rating : 4.0/5 (33 download)
Download or read book Particle Physics Reference Library written by Stephen Myers and published by Springer Nature. This book was released on 2020-01-01 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third open access volume of the handbook series deals with accelerator physics, design, technology and operations, as well as with beam optics, dynamics and diagnostics. A joint CERN-Springer initiative, the "Particle Physics Reference Library" provides revised and updated contributions based on previously published material in the well-known Landolt-Boernstein series on particle physics, accelerators and detectors (volumes 21A,B1,B2,C), which took stock of the field approximately one decade ago. Central to this new initiative is publication under full open access.
Author : Heinrich Schwoerer
Publisher : Springer Science & Business Media
ISBN 13 : 3540302719
Total Pages : 258 pages
Book Rating : 4.5/5 (43 download)
Download or read book Lasers and Nuclei written by Heinrich Schwoerer and published by Springer Science & Business Media. This book was released on 2006-05-22 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lasers and Nuclei describes the generation of high-energy-particle radiation with high-intensity lasers and its application to nuclear science. A basic introduction to laser--matter interaction at high fields is complemented by detailed presentations of state of the art laser particle acceleration and elementary laser nuclear experiments. The text also discusses future applications of lasers in nuclear science, for example in nuclear astrophysics, isotope generation, nuclear fuel physics and proton and neutron imaging.
Author :
Publisher :
ISBN 13 :
Total Pages : 976 pages
Book Rating : 4.:/5 (31 download)
Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1990 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lists citations with abstracts for aerospace related reports obtained from world wide sources and announces documents that have recently been entered into the NASA Scientific and Technical Information Database.
Author : J. Sigmond
Publisher : Springer Science & Business Media
ISBN 13 : 9781851662340
Total Pages : 242 pages
Book Rating : 4.6/5 (623 download)
Download or read book High-Power Lasers: Improvements and Applications written by J. Sigmond and published by Springer Science & Business Media. This book was released on 1988-05-31 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : C.K. Birdsall
Publisher : CRC Press
ISBN 13 : 1482263068
Total Pages : 504 pages
Book Rating : 4.4/5 (822 download)
Download or read book Plasma Physics via Computer Simulation written by C.K. Birdsall and published by CRC Press. This book was released on 2018-10-08 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Divided into three main parts, the book guides the reader to an understanding of the basic concepts in this fascinating field of research. Part 1 introduces you to the fundamental concepts of simulation. It examines one-dimensional electrostatic codes and electromagnetic codes, and describes the numerical methods and analysis. Part 2 explores the mathematics and physics behind the algorithms used in Part 1. In Part 3, the authors address some of the more complicated simulations in two and three dimensions. The book introduces projects to encourage practical work Readers can download plasma modeling and simulation software — the ES1 program — with implementations for PCs and Unix systems along with the original FORTRAN source code. Now available in paperback, Plasma Physics via Computer Simulation is an ideal complement to plasma physics courses and for self-study.
