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Fast Facts For Patients Colorectal Cancer With Kras Mutation
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Book Synopsis Fast Facts for Patients: Colorectal Cancer with KRAS Mutation by : Rona Yaeger
Download or read book Fast Facts for Patients: Colorectal Cancer with KRAS Mutation written by Rona Yaeger and published by Karger Medical and Scientific Publishers. This book was released on 2024-03-20 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer (CRC) is cancer that begins in the colon or rectum of the digestive system. KRAS is a protein that sends signals to cells telling them to divide. In healthy cells, KRAS can be switched on and off. In some cancer cells, gene mutations cause changes in the KRAS protein that mean it is constantly switched on, driving cells to divide. KRAS mutation status can be used to guide treatment decisions. New treatments that target a KRAS mutation have been approved for non-small cell lung cancer and are now being tested for CRC. Other treatments are also being developed.
Book Synopsis Fast Facts for Patients: Non-small Cell Lung Cancer with KRAS Mutation by : A.-M. Baird
Download or read book Fast Facts for Patients: Non-small Cell Lung Cancer with KRAS Mutation written by A.-M. Baird and published by Karger Medical and Scientific Publishers. This book was released on 2023-03-09 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-small cell lung cancer (NSCLC) is one of two main types of lung cancer. Some lung cancers spread to other parts of the body before they are diagnosed. A cancer that has spread is called ‘metastatic’. New lung cancer treatments are being developed that directly target the gene mutations that control how cancers grow and spread. The most important gene mutations in cancer are called ‘driver mutations’. In NSCLC, this includes KRAS mutations, which can be used as targets for treatment. There are new treatments designed for lung cancers with a KRAS mutation that are already available. And more are being developed. Treatments in development are tested in clinical trials. There are several different phases of clinical trials that people with cancer can take part in. This booklet aims to help patients with NSCLC understand their options so that they can talk to their doctors, nurses, and medical team about their cancer and its treatment. Table of Contents: • What is non-small cell lung cancer? • How can lung cancer develop? • What is metastatic NSCLC? • More about genes and cancer • Oncogenes and cancer • Driver mutations and biomarkers • How your doctor knows your cancer is KRAS-positive • More about KRAS • What does having a KRAS-positive cancer mean for me? • Talking to your doctor about your treatment • About clinical trials and research • Finding further information and support
Author :Anne-Marie Baird Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318072494 Total Pages :39 pages Book Rating :4.3/5 (18 download)
Book Synopsis Fast Facts for Patients: Non-small Cell Lung Cancer with KRAS Mutation by : Anne-Marie Baird
Download or read book Fast Facts for Patients: Non-small Cell Lung Cancer with KRAS Mutation written by Anne-Marie Baird and published by Karger Medical and Scientific Publishers. This book was released on 2023-03-31 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-small cell lung cancer (NSCLC) is one of two main types of lung cancer. Some lung cancers spread to other parts of the body before they are diagnosed. A cancer that has spread is called ‘metastatic’. New lung cancer treatments are being developed that directly target the gene mutations that control how cancers grow and spread. The most important gene mutations in cancer are called ‘driver mutations’. In NSCLC, this includes KRAS mutations, which can be used as targets for treatment. There are new treatments designed for lung cancers with a KRAS mutation that are already available. And more are being developed. Treatments in development are tested in clinical trials. There are several different phases of clinical trials that people with cancer can take part in. This booklet aims to help patients with NSCLC understand their options so that they can talk to their doctors, nurses, and medical team about their cancer and its treatment. Table of Contents: • What is non-small cell lung cancer? • How can lung cancer develop? • What is metastatic NSCLC? • More about genes and cancer • Oncogenes and cancer • Driver mutations and biomarkers • How your doctor knows your cancer is KRAS-positive • More about KRAS • What does having a KRAS-positive cancer mean for me? • Talking to your doctor about your treatment • About clinical trials and research • Finding further information and support
Book Synopsis Fast Facts for Patients: Colorectal Cancer with KRAS Mutation by : Rona Yaeger
Download or read book Fast Facts for Patients: Colorectal Cancer with KRAS Mutation written by Rona Yaeger and published by Karger Medical and Scientific Publishers. This book was released on 2024-03-25 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer (CRC) is cancer that begins in the colon or rectum of the digestive system. KRAS is a protein that sends signals to cells telling them to divide. In healthy cells, KRAS can be switched on and off. In some cancer cells, gene mutations cause changes in the KRAS protein that mean it is constantly switched on, driving cells to divide. KRAS mutation status can be used to guide treatment decisions. New treatments that target a KRAS mutation have been approved for non-small cell lung cancer and are now being tested for CRC. Other treatments are also being developed.
Book Synopsis Fast Facts: Colorectal Cancer by : Irving Taylor
Download or read book Fast Facts: Colorectal Cancer written by Irving Taylor and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early detection is essential if patients are to be offered the best chance of survival from colorectal cancer. Many of the genetic and environmental factors that contribute to the development of this disease are now well recognized. In addition, new drug therapies have changed the way colorectal cancer is treated. 'Fast Facts: Colorectal Cancer' delivers concise and highly practical information on all aspects of this all too common disease. This fully updated third edition provides invaluable information for the primary care team, who are key to the screening and diagnosis of the disease, and essential to the provision of optimal support services. Written by three international specialists, this new edition has been substantially revised and expanded, and includes: • Discussion of the latest therapeutic developments in both the adjuvant and metastatic setting • Updated information on the genetic factors that contribute to development of the disease • Expert guidance on diagnosis, screening and treatments Contents: • Epidemiology and pathophysiology • Clinical presentation • Diagnosis and staging • Screening and surveillance • Treatment of the primary disease • Large bowel obstruction • Advanced and recurrent disease • Multidisciplinary management • Future trends • Useful Resources
Download or read book Fast Facts written by ProQuest and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Colorectal Cancer Screening Saves Lives by :
Download or read book Colorectal Cancer Screening Saves Lives written by and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fast Facts: Molecular Profiling in Solid Tumors by : P. Cheema
Download or read book Fast Facts: Molecular Profiling in Solid Tumors written by P. Cheema and published by Karger Medical and Scientific Publishers. This book was released on 2022-12-06 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identifying tumor-specific molecular aberrations via molecular profiling is vital for the use of targeted therapies. Understanding a patient’s unique tumor genetics provides predictive and prognostic information that enables a personalized care plan to be put in place, improving outcomes and minimizing ineffective treatments. 'Fast Facts: Molecular Profiling in Solid Tumors' provides a firm knowledge foundation of somatic molecular profiling methodologies, key information to help with the use of molecular profiling in daily practice and advice on communicating with patients about molecular testing and results. Table of Contents: • Molecular profiling: the basics • Rationale for testing • Sample collection • Test selection and process • Interpreting the report • Talking to patients • Challenges and opportunities
Book Synopsis Genetics of Colorectal Cancer by : John D. Potter
Download or read book Genetics of Colorectal Cancer written by John D. Potter and published by Springer. This book was released on 2008-12-08 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.
Author :Bernardo L. Rapoport Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318068187 Total Pages :109 pages Book Rating :4.3/5 (18 download)
Book Synopsis Fast Facts: Comprehensive Genomic Profiling by : Bernardo L. Rapoport
Download or read book Fast Facts: Comprehensive Genomic Profiling written by Bernardo L. Rapoport and published by Karger Medical and Scientific Publishers. This book was released on 2020-10-20 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: • Genetic mutations and biomarkers • Understanding next-generation sequencing • Elements of comprehensive genomic profiles • Role in precision oncology • Predictive and prognostic biomarkers • Overcoming barriers to genotype-directed therapy
Book Synopsis Rectal Cancer Treatment by : M.W. Büchler
Download or read book Rectal Cancer Treatment written by M.W. Büchler and published by Springer Science & Business Media. This book was released on 2005-10-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.
Author :Karthik Ramasamy Publisher :Karger Medical and Scientific Publishers ISBN 13 :1910797332 Total Pages :162 pages Book Rating :4.9/5 (17 download)
Book Synopsis Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias by : Karthik Ramasamy
Download or read book Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias written by Karthik Ramasamy and published by Karger Medical and Scientific Publishers. This book was released on 2017-01-09 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of multiple myeloma (MM) is growing at a formidable pace, particularly in terms of risk factors and potential drug targets. Minimal residual disease (MRD) negativity is set to become the new benchmark in treatment, and cytogenetic analysis is now paving the way for personalized therapies. This second edition of 'Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias' includes: - the new IMWG SLiM CRAB criteria - the latest advances in diagnostic tests and imaging - cytogenetics and genetic profiling - induction therapy prior to SCT - new lenalidomide- and bortezomib-based regimens - second-generation proteasome inhibitors, histone deacetylase inhibitors and monoclonal antibodies treatments. This Fast Facts handbook provides a comprehensive overview of MM and other plasma cell dyscrasias, from bench to bedside, presenting the pathogenesis, diagnosis and treatment in the context of daily clinical practice. Contents: • Epidemiology and etiology Predisposing conditions associated with MM • Pathophysiology of MM and MGUS • Diagnosis, staging and monitoring of multiple myeloma • Genetics and multiple myeloma • Treatment of newly diagnosed multiple myeloma • Stem cell transplantation in multiple myeloma • Relapsed and refractory multiple myeloma • Bone disease and renal complications • AL amyloidosis • Rare plasma cell dyscrasias • Supportive care
Book Synopsis Colorectal Cancer Liver Metastases by : Mauro Monteiro Correia
Download or read book Colorectal Cancer Liver Metastases written by Mauro Monteiro Correia and published by Springer Nature. This book was released on 2019-12-28 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.
Book Synopsis The Key Facts on Cancer by : Patrick W. Nee
Download or read book The Key Facts on Cancer written by Patrick W. Nee and published by Patrick W. Nee. This book was released on with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Key Facts on Cancer provides readers with essential, easy-to-read information on the life-threatening disease. Compiled in a simplified manner, this guide helps patients navigate this painful process without enduring the complicated nature of medical terminology. By making a patient-friendly manual to the causes, treatment, and ongoing research of cancer, one can easily determine what they are facing and how to live their life to the fullest.
Book Synopsis How Tobacco Smoke Causes Disease by :
Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Colorectal Cancer written by Jindong Chen and published by BoD – Books on Demand. This book was released on 2018-05-16 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: With international experts sharing their experience and knowledge on these different aspects in the management of colorectal cancer, this book has this opportunity to offer all physicians treating colorectal cancer, as well as researchers, updated information concerning the biology, diagnosis, screening, and treatment of colorectal carcinoma. This book provides a detailed evaluation of diagnostic modalities, in-depth analysis of screening for colorectal cancer, recent advances in treatment, and principles and trends in the management of colorectal cancer. This updated knowledge will be an interesting and informative read for any clinician involved in the management of patients with colorectal cancer. In addition, readers such as related physicians, researchers, and colorectal cancer patients are potential beneficiaries of this book.
Author :Kevin M. Haigis, Ph.D. Publisher :Springer Science & Business Media ISBN 13 :146148412X Total Pages :319 pages Book Rating :4.4/5 (614 download)
Book Synopsis Molecular Pathogenesis of Colorectal Cancer by : Kevin M. Haigis, Ph.D.
Download or read book Molecular Pathogenesis of Colorectal Cancer written by Kevin M. Haigis, Ph.D. and published by Springer Science & Business Media. This book was released on 2013-10-02 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.
