Fast Facts for Patients: Chronic Lymphocytic Leukemia

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Publisher :
ISBN 13 : 9783318072273
Total Pages : 0 pages
Book Rating : 4.0/5 (722 download)

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Book Synopsis Fast Facts for Patients: Chronic Lymphocytic Leukemia by : Kathryn Huntley

Download or read book Fast Facts for Patients: Chronic Lymphocytic Leukemia written by Kathryn Huntley and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is a slow-growing type of blood cancer and the most common form of leukemia in adults. CLL results in large numbers of abnormal B lymphocytes in the bone marrow and prevents the production of healthy blood cells. It is more commonly diagnosed in older people: almost 80% of cases are in people over 60 years old. Changes in chromosomes or genes in some patients affect how the disease develops and what treatment is prescribed. CLL cannot be completely cured but many people will have a normal lifespan and a good quality of life.

Fast Facts: Leukemia

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318069965
Total Pages : 138 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Leukemia by : Justin Loke

Download or read book Fast Facts: Leukemia written by Justin Loke and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-22 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukemia is a hematologic malignancy arising from hematopoietic stem cells (HSCs) in the bone marrow. Starting with a detailed description of hematopoiesis and what goes wrong in leukemia, this concise guide covers all aspects of the four most common subtypes of the disease. Although the incidence and prevalence of leukemia are rising worldwide, survival rates are also increasing. However, both the effects of the disease and the adverse effects of treatment remain complex challenges. Yet, as our understanding of the molecular landscape increases, therapeutic options are becoming more personalized. This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care. Table of Contents: • Understanding blood and its components • What is leukemia? • Epidemiology, etiology and risk factors • Diagnosis • Staging and general management • Supportive care • Emergencies in leukemia

Fast Facts: Chronic Lymphocytic Leukemia

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318069736
Total Pages : 74 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Chronic Lymphocytic Leukemia by : Toby A Eyre

Download or read book Fast Facts: Chronic Lymphocytic Leukemia written by Toby A Eyre and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-11 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. 'Fast Facts: Chronic Lymphocytic Leukemia' covers the epidemiology, etiology, diagnosis and staging of the disease, and the molecular and genetic aspects that underpin treatment and prognosis. It provides a concise overview of treatment options, in both the front-line and relapsed/refractory settings, with particular focus on the novel targeted agents that have overcome many adverse prognostic factors, improving overall survival. Table of Contents: • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions

Fast Facts for Patients: Chronic Lymphocytic Leukemia

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318072524
Total Pages : 52 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts for Patients: Chronic Lymphocytic Leukemia by : Kathryn Huntley

Download or read book Fast Facts for Patients: Chronic Lymphocytic Leukemia written by Kathryn Huntley and published by Karger Medical and Scientific Publishers. This book was released on 2023-07-05 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is a slow-growing type of blood cancer and the most common form of leukemia in adults. CLL results in large numbers of abnormal B lymphocytes in the bone marrow and prevents the production of healthy blood cells. It is more commonly diagnosed in older people: almost 80% of cases are in people over 60 years old. Changes in chromosomes or genes in some patients affect how the disease develops and what treatment is prescribed. CLL cannot be completely cured but many people will have a normal lifespan and a good quality of life.

Fast Facts: Acute Lymphoblastic Leukemia

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318069779
Total Pages : 108 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Acute Lymphoblastic Leukemia by : Bela Wrench

Download or read book Fast Facts: Acute Lymphoblastic Leukemia written by Bela Wrench and published by Karger Medical and Scientific Publishers. This book was released on 2022-06-30 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute lymphoblastic leukemia (ALL) is the most diagnosed childhood cancer worldwide. Although rare in adults, this aggressive cancer also shows a second smaller incidence peak in later middle age.

Modern genetic profiling techniques are providing a better understanding of the molecular biology of ALL, which, in turn, is leading to significant advances in diagnosis, prognostication and therapy selection. Ongoing refinement of risk-adapted frontline treatment protocols, use of novel targeted therapies and better supportive care are improving outcomes for patients with ALL.

Fast Facts: Acute Lymphoblastic Leukemia covers the epidemiology, etiology, diagnosis and classification of ALL as well as the measurement of minimal residual disease to determine prognosis. It provides guidance on frontline therapies and the treatment of relapsed and refractory ALL, including the use of newer targeted agents and the role of allogeneic stem-cell transplantation. Looking to the future, it also considers the approaches and refinements that are in development for ALL. Table of Contents:

  • Epidemiology, pathophysiology and etiology
  • Diagnosis
  • Prognostic factors
  • Treatment
  • Relapsed or refractory ALL
  • Future directions
  • Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318068349
    Total Pages : 54 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia by : S. Potluri

    Download or read book Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia written by S. Potluri and published by Karger Medical and Scientific Publishers. This book was released on 2021-01-26 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tyrosine kinase inhibitor (TKI) imatinib was the first treatment to specifically target cancer cells, rather than the relatively indiscriminate effects of conventional chemotherapy on any rapidly dividing cells. This concept of targeted treatment in cancer is one of the important advances in modern medicine in the last 30 years. Indeed, treatment with TKIs has transformed chronic myeloid leukemia (CML) from a cancer with a poor prognosis to one in which many patients can expect a normal lifespan. Success with the TKIs has prompted the question of whether it is desirable – or feasible – for patients to remain on treatment for long periods. While the TKIs are targeted, they are associated with considerable toxicity, and long-term treatment has important economic implications for health services and patients. Thus, the concept of treatment-free remission (TFR) has emerged for patients in deep clinical remission. Clinical research over the last decade has focused on whether treatment can be stopped, how to best monitor patients while off treatment, and how to intervene before a clinical relapse. As this research progresses, the tantalizing prospect of a cure for some patients seems increasingly feasible. This new Fast Facts title outlines this trail-blazing approach to the long-term management of patients living with CML in remission. It explains the concepts of molecular and hematologic relapse, the highly sensitive technologies that allow disease monitoring, and how TFR is best managed in practice. It is a concise educational resource, ideal for any healthcare professional involved in the treatment of patients with CML who wants to understand TFR, particularly clinical nurse specialists and pharmacists who increasingly help clinicians to run CML clinics. Table of Contents: • The concept of treatment-free remission • Measurement of disease burden • Clinical practice • Future directions

    Fast Facts: Chronic Lymphocytic Leukemia

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318071609
    Total Pages : 80 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Chronic Lymphocytic Leukemia by : Toby A. Eyre

    Download or read book Fast Facts: Chronic Lymphocytic Leukemia written by Toby A. Eyre and published by Karger Medical and Scientific Publishers. This book was released on 2023-05-23 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. Table of Contents • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions

    Fast Facts for Patients: Follicular Lymphoma

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    Author :
    Publisher :
    ISBN 13 : 9783318072952
    Total Pages : 0 pages
    Book Rating : 4.0/5 (729 download)

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    Book Synopsis Fast Facts for Patients: Follicular Lymphoma by :

    Download or read book Fast Facts for Patients: Follicular Lymphoma written by and published by . This book was released on 2024 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

    Fast Facts: Chronic Lymphocytic Leukemia

    Download Fast Facts: Chronic Lymphocytic Leukemia PDF Online Free

    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318069744
    Total Pages : 74 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Chronic Lymphocytic Leukemia by : T.A. Eyre

    Download or read book Fast Facts: Chronic Lymphocytic Leukemia written by T.A. Eyre and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-11 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. 'Fast Facts: Chronic Lymphocytic Leukemia' covers the epidemiology, etiology, diagnosis and staging of the disease, and the molecular and genetic aspects that underpin treatment and prognosis. It provides a concise overview of treatment options, in both the front-line and relapsed/refractory settings, with particular focus on the novel targeted agents that have overcome many adverse prognostic factors, improving overall survival. Table of Contents: • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions

    Fast Facts: Leukemia

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318069493
    Total Pages : 138 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Leukemia by : J. Loke

    Download or read book Fast Facts: Leukemia written by J. Loke and published by Karger Medical and Scientific Publishers. This book was released on 2022-03-02 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukemia is a hematologic malignancy arising from hematopoietic stem cells (HSCs) in the bone marrow. Starting with a detailed description of hematopoiesis and what goes wrong in leukemia, this concise guide covers all aspects of the four most common subtypes of the disease. Although the incidence and prevalence of leukemia are rising worldwide, survival rates are also increasing. However, both the effects of the disease and the adverse effects of treatment remain complex challenges. Yet, as our understanding of the molecular landscape increases, therapeutic options are becoming more personalized. This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care. Table of Contents: • Understanding blood and its components • What is leukemia? • Epidemiology, etiology and risk factors • Diagnosis • Staging and general management • Supportive care • Emergencies in leukemia

    Fast Facts: Leucemia

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318066338
    Total Pages : 140 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Leucemia by : J. Loke

    Download or read book Fast Facts: Leucemia written by J. Loke and published by Karger Medical and Scientific Publishers. This book was released on 2019-11-28 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aunque la incidencia y prevalencia de leucemia está aumentando a nivel mundial, los avances en el diagnóstico y el tratamiento indican que las tasas de supervivencia también están aumentando. Comenzando con una descripción detallada de la hematopoyesis y lo que está mal en caso de la leucemia, esta guía concisa abarca todos los aspectos de los cuatro subtipos más frecuentes de la enfermedad: leucemia mieloide aguda (AML), leucemia linfoblástica aguda (ALL), leucemia mieloide crónica (CML) y leucemia linfocítica crónica (CLL). Este libro considera las causas y factores de riesgo para cada subtipo de leucemia, las pruebas diagnósticas iniciales y confirmatorias (incluyendo métodos de citogenética y genética molecular) y las opciones de tratamiento más recientes. Tanto los efectos de la enfermedad como los efectos adversos del tratamiento siguen representando un desafío complejo y se considera el abordaje multidisciplinario necesario para una atención de apoyo efectiva. Por último, se examinan las complicaciones urgentes que requieren atención de emergencia. Diseñado como una guía integral para enfermeras especializadas, médicos de atención primaria y residentes de hematología/oncología, este recurso ayudará a quienes no son especialistas a identificar la leucemia en etapas tempranas y proporciona una comprensión detallada de la patología y la base genética de la enfermedad, las opciones de tratamiento y los abordajes efectivos a la atención de urgencia y cuidados de apoyo.

    Fast Facts: Lymphoma

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 1910797952
    Total Pages : 161 pages
    Book Rating : 4.9/5 (17 download)

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    Book Synopsis Fast Facts: Lymphoma by : C. Hatton

    Download or read book Fast Facts: Lymphoma written by C. Hatton and published by Karger Medical and Scientific Publishers. This book was released on 2018-10-16 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphoma affects all ages. Advances in diagnostic cellular and molecular techniques coupled with new treatment options are improving patient outcomes. This third edition of our bestselling 'Fast Facts: Lymphoma' distills the most important aspects of diagnosis and management into an up-to-date and highly accessible well-illustrated overview that includes: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and histology • a synopsis of current laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology, and updated to include the latest molecular genetic techniques • key aspects of staging and initial therapy • clearly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies and chimeric antigen receptor T cells (CAR T cells) • a practical overview of supportive care for the complications of lymphoma. Written by three lymphoma experts from the UK and USA, 'Fast Facts: Lymphoma' gives an interesting international perspective to this challenging disease. Its clarity and colorful format make it a valuable resource for senior health professionals seeking an accessible update in this area of hemato-oncology, trainee doctors and specialist nurses who are new to it, and individuals affected by lymphoma and seeking more information. Contents: • Epidemiology • Cellular and molecular aspects • Presentation, biopsy and diagnostic laboratory techniques • Staging and general management principles • Aggressive B-cell lymphomas • Indolent B-cell lymphomas • T-cell and natural-killer cell lymphomas • Immunocompromised and HIV-positive patients • Hodgkin lymphoma • Treatment modalities • Supportive care

    Childhood Acute Lymphoblastic Leukemia

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    Author :
    Publisher : Springer
    ISBN 13 : 3319397087
    Total Pages : 345 pages
    Book Rating : 4.3/5 (193 download)

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    Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora

    Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

    Fast Facts: Skin Cancer

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 1908541393
    Total Pages : 118 pages
    Book Rating : 4.9/5 (85 download)

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    Book Synopsis Fast Facts: Skin Cancer by : Karen L. Agnew

    Download or read book Fast Facts: Skin Cancer written by Karen L. Agnew and published by Karger Medical and Scientific Publishers. This book was released on 2015-09-16 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin cancer is both preventable and treatable, yet it is becoming alarmingly common. The key to successful treatment (other than education and prevention) is early recognition and swift referral. 'Fast Facts: Skin Cancer' has been written by three international experts to equip healthcare professionals with the necessary skills to save lives. Highlights include: • Expert presentation of the basic facts on epidemiology, causation, presentation and management • Over 100 color illustrations to assist with the identification of at-risk individuals and early lesions • Pull-out tables of cancer staging for cutaneous squamous cell carcinoma and melanoma • Advice to give patients on self-examination • A thorough overview of all treatment options: topical therapies, cryotherapy, curettage and electrosurgery, photodynamic therapy and lasers, radiotherapy, surgical excision and Mohs micrographic surgery • Discussion of preventive measures This fully updated second edition is a practical evidence-based resource, written from an international perspective to reflect national and international guidelines. It will assist clinical practice, education, training, audit and research, and is essential reading for generalists and specialists alike. Contents: • Epidemiology • Pathogenesis • Clinical features and diagnosis • Management • Prognosis • Prevention; Future trends

    Fast Facts: Lymphoma

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 1908541776
    Total Pages : 142 pages
    Book Rating : 4.9/5 (85 download)

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    Book Synopsis Fast Facts: Lymphoma by : Chris Hatton

    Download or read book Fast Facts: Lymphoma written by Chris Hatton and published by Karger Medical and Scientific Publishers. This book was released on 2014-10-31 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hodgkin lymphoma and the many different subtypes of non-Hodgkin lymphoma (NHL) have different responses to treatment, so accurate diagnosis and a rational approach to management are essential. 'Fast Facts: Lymphoma' distills the most important aspects of the diagnosis and management of these complex disorders into a highly accessible well-illustrated summary of the key facts. This fully updated second edition provides: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and basic histology • the latest laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology • key aspects of staging and initial therapy • superbly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies • a practical overview of supportive care for the complications of lymphoma Written by three experts in the field from the UK and USA, 'Fast Facts: Lymphoma' applies an international perspective to this challenging disease in a unique format within the context of clinical practice. It is a valuable resource for trainee doctors and specialist nurses working in the field of hemato-oncology. It will also be of interest to the inquiring patient or carer who wishes to know more about lymphoma. Contents: • Epidemiology • Cellular and molecular aspects • Presentation, biopsy and diagnostic laboratory techniques • Staging and general management principles • Aggressive B-cell lymphomas • Indolent B-cell lymphomas • T-cell and natural-killer cell lymphomas • Immunocompromised and HIV-positive patients • Hodgkin lymphoma • Treatment modalities • Supportive care

    Fast Facts: Rheumatoid Arthritis

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 1905832915
    Total Pages : 118 pages
    Book Rating : 4.9/5 (58 download)

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    Book Synopsis Fast Facts: Rheumatoid Arthritis by : John D. Isaacs

    Download or read book Fast Facts: Rheumatoid Arthritis written by John D. Isaacs and published by Karger Medical and Scientific Publishers. This book was released on 2011-05-01 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly updated second edition of 'Fast Facts: Rheumatoid Arthritis' provides an easy-to-read overview of how the condition is thought to develop and how it is diagnosed, monitored and treated. Written by two leading UK and US rheumatologists, it covers the many recent developments in this field, including: • Recently published classification criteria • The emerging role of anti-CCP autoantibodies • The latest developments in ultrasound and MRI • The association between RA and cardiovascular disease and lung disease • New concepts of undifferentiated arthritis and treatment to remission • The importance of early referral and new biological therapies 'Fast Facts: Rheumatoid Arthritis' provides a well-referenced international perspective on this condition. It is a 'must read' for all healthcare professionals caring for patients with this debilitating inflammatory joint disease. Contents: • The normal joint • Etiology • Pathogenesis • Epidemiology • Clinical features • Investigation • Assessment • Management - traditional measures • Management - biological therapies • Therapeutic developments

    Fast Facts: Medical Statistics

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 1912776677
    Total Pages : 110 pages
    Book Rating : 4.9/5 (127 download)

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    Book Synopsis Fast Facts: Medical Statistics by : Richard Kay

    Download or read book Fast Facts: Medical Statistics written by Richard Kay and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-17 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using real examples from oncology trials, but keeping it simple, this concise resource explains the basic principles of medical statistics so that you can better appraise clinical trial results. Key concepts covered in this book include: • hypothesis testing • Kaplan–Meier curves and other graphic representations of data • calculating the power of a study • the stopping rules for efficacy and futility. ' Fast Facts: Medical Statistics' is aimed at all clinicians, clinical scientists, medical writers and regulatory personnel who need a better understanding of the statistical terms and methods used in the planning of studies and the analysis of clinical trial data. If you have ever wanted to know what a type I error is, how an odds ratio is calculated or what a forest plot is really all about, then this is the book for you. Contents: • Statistical inference • Analysis of time-to-event endpoints • Power and sample size • Multiplicity • Interim analysis • Modeling • Graphical methods