Extracellular Nucleic Acids

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Publisher : Springer Science & Business Media
ISBN 13 : 3642126170
Total Pages : 239 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Extracellular Nucleic Acids by : Yo Kikuchi

Download or read book Extracellular Nucleic Acids written by Yo Kikuchi and published by Springer Science & Business Media. This book was released on 2010-07-23 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular nucleic acids have recently emerged as important players in the fields of biology and the medical sciences. In the last several years, extracellular nucleic acids have been shown to be involved in not only microbial evolution as genetic elements but also to have structural roles in bacterial communities, such as biofilms. Circulating DNA and RNA have been found in human blood and expected to be useful as non-invasive markers for the diagnosis of several diseases. In addition, extracellular nucleic acids have attracted attention as active modulators of the immune system of higher organisms, including humans. This book covers nearly all of the newly developing fields related to extracellular nucleic acids, including those of basic biology, ecology and the medical sciences, and provides readers with the latest knowledge on them.

Nucleic Acids and Proteins in Soil

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Publisher : Springer
ISBN 13 : 9783642067297
Total Pages : 0 pages
Book Rating : 4.0/5 (672 download)

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Book Synopsis Nucleic Acids and Proteins in Soil by : Paolo Nannipieri

Download or read book Nucleic Acids and Proteins in Soil written by Paolo Nannipieri and published by Springer. This book was released on 2010-02-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With millions of different bacterial species living in soil, the microbial community is extremely complex, varying at very small scales. Microbe-driven functions are essential for most processes in soil. Thus, a better understanding of this microbial diversity will be invaluable for the management of the various soil functions. Nucleic Acids and Proteins in Soil combines traditional approaches in soil microbiology and biochemistry with the latest techniques in molecular microbial ecology. Included are methods to analyse the presence and importance of nucleic acids and proteins both inside and outside microbial cells, the horizontal gene transfer which drives bacterial diversity, as well as soil proteomes. Further chapters describe techniques such as PCR, fingerprinting, the challenging use of gene arrays for structural and functional analysis, stable isotope probing to identify in situ metabolic functions, and the use of marker and reporter genes in soil microbial ecology.

Cell-Free Nucleic Acids

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Publisher : MDPI
ISBN 13 : 3039280740
Total Pages : 248 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Cell-Free Nucleic Acids by : Bálint Nagy

Download or read book Cell-Free Nucleic Acids written by Bálint Nagy and published by MDPI. This book was released on 2020-01-21 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The deficits of mammography and the potential of noninvasive diagnostic testing using circulating miRNA profiles are presented in our first review article. Exosomes are important in the transfer of genetic information. The current knowledge on exosome-associated DNAs and on vesicle-associated DNAs and their role in pregnancy-related complications is presented in the next article. The major obstacle is the lack of a standardized technique for the isolation and measurement of exosomes. One review has summarized the latest results on cell-free nucleic acids in inflammatory bowel disease (IBD). Despite the extensive research, the etiology and exact pathogenesis are still unclear, although similarity to the cell-free ribonucleic acids (cfRNAs) observed in other autoimmune diseases seems to be relevant in IBD. Liquid biopsy is a useful tool for the differentiation of leiomyomas and sarcomas in the corpus uteri. One manuscript has collected the most important knowledge of mesenchymal uterine tumors and shows the benefits of noninvasive sampling. Microchimerism has also recently become a hot topic. It is discussed in the context of various forms of transplantation and transplantation-related advanced therapies, the available cell-free nucleic acid (cfNA) markers, and the detection platforms that have been introduced. Ovarian cancer is one of the leading serious malignancies among women, with a high incidence of mortality; the introduction of new noninvasive diagnostic markers could help in its early detection and treatment monitoring. Epigenetic regulation is very important during the development of diseases and drug resistance. Methylation changes are important signs during ovarian cancer development, and it seems that the CDH1 gene is a potential candidate for being a noninvasive biomarker in the diagnosis of ovarian cancer. Preeclampsia is a mysterious disease—despite intensive research, the exact details of its development are unknown. It seems that cell-free nucleic acids could serve as biomarkers for the early detection of this disease. Three research papers deal with the prenatal application of cfDNA. Copy number variants (CNVs) are important subjects for the study of human genome variations, as CNVs can contribute to population diversity and human genetic diseases. These are useful in NIPT as a source of population specific data. The reliability of NIPT depends on the accurate estimation of fetal fraction. Improvement in the success rate of in vitro fertilization (IVF) and embryo transfer (ET) is an important goal. The measurement of embryo-specific small noncoding RNAs in culture media could improve the efficiency of ET.

Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring

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Publisher : Springer
ISBN 13 : 9401791686
Total Pages : 476 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring by : Peter B. Gahan

Download or read book Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring written by Peter B. Gahan and published by Springer. This book was released on 2014-11-18 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals. Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for treatment, treatment monitoring and clinical follow-up. In addition, the use in fetal medicine allows the early detection of fetal sex, Rh factor and aneuploid disorders as well as following both fetal and premature born infant development. This volume is intended as a primer for those who are interested in entering the field of circulating nucleic acids. The areas covered in this volume include: · Background and general biology of circulating nucleic acids · Methodology · Applications of circulating nucleic acids · Quality Assurance · Ethics

Vascular Biology, Haemostasis and Extracellular Nucleic Acids in Vascular Diseases and Immunity. A Tribute to Klaus T. Preissner

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Publisher : Frontiers Media SA
ISBN 13 : 2889742040
Total Pages : 156 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Vascular Biology, Haemostasis and Extracellular Nucleic Acids in Vascular Diseases and Immunity. A Tribute to Klaus T. Preissner by : Ritva Tikkanen

Download or read book Vascular Biology, Haemostasis and Extracellular Nucleic Acids in Vascular Diseases and Immunity. A Tribute to Klaus T. Preissner written by Ritva Tikkanen and published by Frontiers Media SA. This book was released on 2022-01-28 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editor Prof. Ritva Tikkanen Receives Research Funding From Neurogene Inc. and GC Pharma for Studies Unrelated to the Subject. Topic Editor Prof. Carl Blobel is Co-Inventor on a Patent Describing a Method of Identifying Agents for Combination With Inhibitors of iRhoms. He and the Hospital for Special Surgery (New York, USA) are Investigating Suitable Approaches to Identify iRhom Inhibitors, and are Co-Founders of a Small Company Called SciRhom in Munich to Pursue These Efforts. Topic Editor Dr. Sylvia Fischer Declares no Competing Interests With Regards to the Research Topic Subject.

Microbial Extracellular Polymeric Substances

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Publisher : Springer Science & Business Media
ISBN 13 : 3642601472
Total Pages : 266 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Microbial Extracellular Polymeric Substances by : Jost Wingender

Download or read book Microbial Extracellular Polymeric Substances written by Jost Wingender and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial extracellular polymeric substances (EPS) are the key components for the aggregation of microorganisms in biofilms, flocs and sludge. They are composed of polysaccharides, proteins, nucleic acids, lipids and other biological macromolecules. EPS provide a highly hydrated gel matrix in which microbial cells can establish stable synergistic consortia. Cohesion and adhesion as well as morphology, structure, biological function and other properties such as mechanical stability, diffusion, sorption and optical properties of microbial aggregates are determined by the EPS matrix. Also, the protection of biofilm organisms against biocides is attributed to the EPS. Their matrix allows phase separation in biofiltration and is also important for the degradation of particulate material which is of great importance for the self purification processes in surface waters and for waste water treatment.

Circulating Nucleic Acids in Serum and Plasma – CNAPS IX

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Author :
Publisher : Springer
ISBN 13 : 3319420445
Total Pages : 220 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Circulating Nucleic Acids in Serum and Plasma – CNAPS IX by : Peter B. Gahan

Download or read book Circulating Nucleic Acids in Serum and Plasma – CNAPS IX written by Peter B. Gahan and published by Springer. This book was released on 2016-10-17 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book will present the progress made since the last meeting in fall 2013 concerning the analysis of circulating extra-cellular nucleic acids. There are a modest number of laboratories involved in this field, nevertheless the number of papers published by researchers is extensive. The articles which will be published in this meeting report will be a valuable contribution for researchers and research students alike and will help them to stay on top of the developments in different research areas and to „cross borders“ between them.

Circulating Nucleic Acids in Plasma and Serum

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Publisher : Springer Science & Business Media
ISBN 13 : 9048193826
Total Pages : 279 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Circulating Nucleic Acids in Plasma and Serum by : Peter B. Gahan

Download or read book Circulating Nucleic Acids in Plasma and Serum written by Peter B. Gahan and published by Springer Science & Business Media. This book was released on 2010-10-08 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA and RNA fractions have been isolated from the whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and clinical patients. Recent developments are presented concerning the isolation, quantification and analysis of these molecules and their use in the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis.

The Nucleic Acids

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Publisher :
ISBN 13 :
Total Pages : 712 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Nucleic Acids by : Erwin Chargaff

Download or read book The Nucleic Acids written by Erwin Chargaff and published by . This book was released on 1955 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Spherical Nucleic Acids

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Publisher : CRC Press
ISBN 13 : 0429578067
Total Pages : 1806 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Spherical Nucleic Acids by : Chad A. Mirkin

Download or read book Spherical Nucleic Acids written by Chad A. Mirkin and published by CRC Press. This book was released on 2020-09-01 with total page 1806 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spherical nucleic acids (SNAs) comprise a nanoparticle core and a densely packed and highly oriented nucleic acid shell, typically DNA or RNA. They have novel architecture-dependent properties that distinguish them from all other forms of nucleic acids and make them useful in materials synthesis, catalysis, diagnostics, therapeutics, and optics/plasmonics. This book covers over two decades of Dr. Mirkin’s research on SNAs and their anisotropic analogues, including synthesis and fundamental properties, and applications in colloidal crystallization, adaptive matter, and nanomedicine, spanning extra- and intracellular diagnostics, gene regulation, and immunomodulation. It is a reprint volume that compiles 101 key papers from high-impact journals in this research area published by the Mirkin Group at Northwestern University, Illinois, USA, within the International Institute for Nanotechnology, and collaborators. Volume 1 provides an overview and a historical framework of engineering matter from DNA-modified constructs and discusses the enabling features of nucleic acid–functionalized nanomaterials. Volume 2 covers design rules for colloidal crystallization, building blocks for crystal engineering, and DNA and RNA as programmable bonds. Volume 3 discusses colloidal crystallization processes and routes to hierarchical assembly, dynamic nanoparticle superlattices, surface-based and template-confined colloidal crystallization, optics and plasmonics with nanoparticle superlattices, and postsynthetic modification and catalysis with nanoparticle superlattices. Volume 4 covers diagnostic modalities, and intracellular therapeutic and diagnostic schemes based upon nucleic acid–functionalized nanomaterials.

Progress in Nucleic Acid Research and Molecular Biology

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Publisher : Academic Press
ISBN 13 : 0080863485
Total Pages : 365 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Progress in Nucleic Acid Research and Molecular Biology by :

Download or read book Progress in Nucleic Acid Research and Molecular Biology written by and published by Academic Press. This book was released on 1998-06-02 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a forum for discussion of new discoveries, approaches and ideas in molecular biology Contributions from leaders in their fields Abundant references

Nucleic Acids and Proteins in Soil

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Publisher : Springer Science & Business Media
ISBN 13 : 354029449X
Total Pages : 468 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Nucleic Acids and Proteins in Soil by : Paolo Nannipieri

Download or read book Nucleic Acids and Proteins in Soil written by Paolo Nannipieri and published by Springer Science & Business Media. This book was released on 2006-09-22 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: With millions of different bacterial species living in soil, the microbial community is extremely complex, varying at very small scales. Microbe-driven functions are essential for most processes in soil. Thus, a better understanding of this microbial diversity will be invaluable for the management of the various soil functions. Nucleic Acids and Proteins in Soil combines traditional approaches in soil microbiology and biochemistry with the latest techniques in molecular microbial ecology. Included are methods to analyse the presence and importance of nucleic acids and proteins both inside and outside microbial cells, the horizontal gene transfer which drives bacterial diversity, as well as soil proteomes. Further chapters describe techniques such as PCR, fingerprinting, the challenging use of gene arrays for structural and functional analysis, stable isotope probing to identify in situ metabolic functions, and the use of marker and reporter genes in soil microbial ecology.

Principles of Biology

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Publisher :
ISBN 13 : 9781636350417
Total Pages : pages
Book Rating : 4.3/5 (54 download)

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Book Synopsis Principles of Biology by : Lisa Bartee

Download or read book Principles of Biology written by Lisa Bartee and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proteins: Sustainable Source, Processing and Applications

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Publisher : Academic Press
ISBN 13 : 012817286X
Total Pages : 358 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Proteins: Sustainable Source, Processing and Applications by : Charis M. Galanakis

Download or read book Proteins: Sustainable Source, Processing and Applications written by Charis M. Galanakis and published by Academic Press. This book was released on 2019-05-30 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins: Sustainable Source, Processing and Applications addresses sustainable proteins, with an emphasis on proteins of animal origin, plant-based and insect proteins, microalgal single cell proteins, extraction, production, the stability and bioengineering of proteins, food applications (e.g. encapsulation, films and coatings), consumer behavior and sustainable consumption. Written in a scientific manner to meet the needs of chemists, food scientists, technologists, new product developers and academics, this book addresses the health effects and properties of proteins, highlights sustainable sources, processes and consumption models, and analyzes the potentiality of already commercialized processes and products. This book is an integral resource that supports the current applications of proteins in the food industry, along with those that are currently under development. Supports the current applications of proteins in the food industry, along with those that are under development Connects the properties and health effects of proteins with sustainable sources, recovery procedures, stability and encapsulation Explores industrial applications that are affected by aforementioned aspects

Current Progress in Nucleic Acids Research

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Publisher : Syrawood Publishing House
ISBN 13 : 9781647403874
Total Pages : 0 pages
Book Rating : 4.4/5 (38 download)

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Book Synopsis Current Progress in Nucleic Acids Research by : Kaison Gibson

Download or read book Current Progress in Nucleic Acids Research written by Kaison Gibson and published by Syrawood Publishing House. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleic acids are large biomolecules that are necessary for all life forms including humans, animals and microorganisms. They are composed of a sugar molecule, nitrogen-containing base, and phosphate groups. Ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) are the two primary types of nucleic acids. Each kind of nucleic acid has a unique structure and performs different functions in the cells. Nucleic acids play an important role in the storage and expression of genomic data. Cell-free nucleic acids (cfNAs) are a mixture of small segments of DNA and RNA present in biological fluids such as blood, saliva and urine. The cfNAs have the potential to act as valuable biomarkers for the diagnosis and prognosis of several diseases including autoimmune diseases, cardiovascular diseases, and cancer. They can also be used for prenatal diagnosis of genetic diseases. This book provides comprehensive insights into the current progress in nucleic acids research. A number of latest researches have been included to keep the readers updated with the latest concepts in this area of study.

Design of Nanostructures for Versatile Therapeutic Applications

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Author :
Publisher : William Andrew
ISBN 13 : 0128136685
Total Pages : 690 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Design of Nanostructures for Versatile Therapeutic Applications by : Alexandru Mihai Grumezescu

Download or read book Design of Nanostructures for Versatile Therapeutic Applications written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-02-03 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design of Nanostructures for Versatile Therapeutic Applications focuses on antimicrobial, antioxidant and nutraceutical applications of nanostructured materials. Many books discuss these subjects, but not from a pharmaceutical point-of-view. This book covers novel approaches related to the modulation of microbial biofilms, antimicrobial therapy and encapsulate polyphenols as antioxidants. Written by an internationally diverse group of academics, this book is an important reference resource for researchers, both in biomaterials science and the pharmaceutical industry. Assesses the most recently developed nanostructures that have potential antimicrobial properties, explaining their novel mechanical aspects Shows how nanoantibiotics can be used to more effectively treat disease Provides a cogent summary of recent developments in nanoantimicrobial discovery, allowing readers to quickly familiarize themselves with the topic